LOCUS       reptomyces_RBGC_681010 16890 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_681010
VERSION     Streptomyces_RBGC_681010
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000816465.3
  ORGANISM  GCF_000816465.3
            .
FEATURES             Location/Qualifiers
     CDS             2..255
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4221969"
                     /pseudo=False
                     /translation="MTEQDGWERKFDHRWANSAEHKEPSARARMLAARWKENPPGPVPF
                     RADPGPVPRRSSWASTAVVLGCVIVVMVLIGIVELGSSR*"
     CDS             complement(318..1345)
                     /protein_domains="PF00891"
                     /protein_domains="PF16864"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4221970"
                     /pseudo=False
                     /translation="MAAAPQLPPHVQLMGLVAGKWMSQPLYVLAELGVADLLADKPRTA
                     AELAVVLEVHPDALGRCMRVAAALGVLAEEPGGRFSLRPMGEALRSDVPCSIRDFTILL
                     GSEPTWASFGAIMHTVRTGAPSFPQVHGTDLFTYLADHPDLARAYQGAWASLTDELAPE
                     AAEAYDFGRYPVIADIGGGHGRMLYHLLGAAPAARGVLMDRPEVLEAARAALAGTPAYE
                     RITFFPGTLPESTPPEADAYLLKNTLHCFADTDARAMLRPLAEALRGRSDARVLVLDTI
                     VPDDASYHWSKFIDIEVMVNNGGRERRLDEWTALFDSAGLRLVSVTPVTPPQSLLEVAA
                     AR*"
     CDS             1491..1675
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4221971"
                     /pseudo=False
                     /translation="MRAPWKGDPAERARQRAAQVEKQREQARRQEDQRLAQELREQQRA
                     AEEREREARRAERDGR*"
     CDS             complement(1718..2433)
                     /protein_domains="PF02909"
                     /protein_domains="PF00440"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4221972"
                     /pseudo=False
                     /translation="MTVRRPRAAAPAGRRPSVTRSALVAAALDVVESEGLDALSMRRLA
                     EQLGVQAASLYWHVQSKEQVLDLLADELLTRVLTEALPADLDRVATGEKAWTDALRETA
                     VNYRAFLRCRRDAARIIAGRFVGGVSLARLLEPILGVLRAGGLSSHDAAYAVYTIIVYV
                     QGFVLHESSPLSASNAEGMERSDALRGVKAAIGALPHDEFPYLAESVDALTEANLDERF
                     RFGLDRLIDGLTAYVR*"
     CDS             2533..4142
                     /protein_domains="PF07690"
                     /protein_domains="TIGR00711"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4221973"
                     /pseudo=False
                     /translation="MSSLPSPAPSAVRRRLILLTLCVSLFMAMLDNTVVNTALPTIERK
                     LGAGISDLQWIVDGYSLALSALMLTASTVGDMFGRRRAFVAGLALFAVGSTVCALSRDV
                     NVLISGRVLQGAGAAAFMPGTLSIIRQVYADERERSTAIGIWAGVSGLGLGLGPLVGGP
                     LVDHFGWPSVFWINVPVGMAGLIAGMLLIPESKDRAGRGLDITGQLLAVAGIGAGVYAT
                     IEGPVRGWSDPAVTGLYIGAGVVLLLFVLVERRSRTPMLDLGFFRDRIFAGSVLAGLFL
                     YLGMFSVLYFLSLWLQVVLGWSPTGAGLVIMPAMVVVACVTPLAGWLTGRIGGGWPMAA
                     GLVCSAFALYGLTRYGTGASYRHFWWLLPVIGMGMGLTITPITATVLDRVPAARAGMAS
                     AVSNTARELGGVLGVAVLGSVLSSRMAERLRERLTAAGVPASERDRLVAATTGGTGRPQ
                     AGLGAGARLSHAVNGAFVDGLHLAELSGCAILLAGALLAVALVRGGRGPAPGSRGGKSG
                     ELDTSDAHDDTDGRATVAT*"
     CDS             complement(4174..5237)
                     /protein_domains="PF00296"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4221974"
                     /pseudo=False
                     /translation="MKHGISLLPDCRPARRSANAYFRDVLALSRFADAAGIDYVKMTEH
                     YLRDYGGYCPDPLSFLSAVAASTSRIRLMTGCLQAAFHHPVQLAAHTAMVDALSGGRLE
                     VGFARAWLPYEFAAFGVPLDESRARFQATIEAVLRLWTEEKVAEDTPFFSYRDATSLPR
                     PTQAPHPPVWCAAVRSRQSFAWIGEAGHGLFVTPPPRREELARTKDMVEVYLDTFREEH
                     AGTDRQPKVAVSIPLYVAETDEQAFATADPFLREYLNVWAESAEDWTGVSSSDYPAYSQ
                     MALSLRNLRIDDFRSVGTAIVGSPQRVVDRILELGEYLSADTFLWQVDYGGQDYASMES
                     SLRLFVDRVLPKLP*"
     CDS             complement(5270..6324)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4221975"
                     /pseudo=False
                     /translation="VTGGVTGGLIGVATVTAGYLLAGRLRCRIRAPRTGREVVDALWAT
                     CTAGAAVLMLLGAGALGFVAPGPGRLLHTLACSRADLLLVPAGLLLGTGEFAAACLLAV
                     VTADAVALLRARVRRRPRMPGRAGTARGGPRSGSGTRAPSWSGRLGPRSGAASPPGSAG
                     DDGAGPGSGRPSGSGVGPGVRRPFRAGAEGRAPLGPAPGSGALAAGGGAEGRGRSPSAG
                     RVMASASSGGSNWLGLARTSWAGRVRGLAGTLPWPALVAVLAAQPLVEELALRGGLVLA
                     LKPLGAVAGLLAAAVATLLVGSLPAVRRSGPAAVTGVAVIATVNSLLFLHTPDVLASAA
                     AQWSFFLLAGA*"
     CDS             complement(6322..6659)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4221976"
                     /pseudo=False
                     /translation="MTRAHGAGAAPVVAGDGVGLRPARAVTGSGTVDVPPGGWAGFLPR
                     SGTGSPPRRAVGEIGAGAPTAVPGPAGTAVPAEPRSRARARAASVGAGTRASLAPVTSP
                     AAEPGGPR*"
     CDS             complement(6657..7447)
                     /protein_domains="PF02517"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4221977"
                     /pseudo=False
                     /translation="MTPIPTHDARLWALAWLALTAASGTTLASHLHVRRLDARGVRMVP
                     VHVSVLAVTAGCGLLLLGPGWLWRGGPGAARAVAAVGAGLLLGAVVVRADGWISRTAAR
                     RPPAVARTPASGEGAAPGRLRPVGLGGTVAPLRSAAHTGADRRWTPTRRDTDLNLALGW
                     LLATAVAEECVFRGVLLRLAVQLDTPVARATGVVAAVAAFALSHVFFGWRQVLAKLPLS
                     VLATVATLALGTVLAAALGHALFNWHVWRHRPVVVQPGATR*"
     CDS             complement(7426..8795)
                     /protein_domains="PF02624"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4221978"
                     /pseudo=False
                     /translation="MTDTLSTEPVALDLRLLRDEDERATALRSRMHSPLCGVLTSMGFL
                     SRTRTGPRMLIASGDLAGVHVLQGRPAPKPGSFHLGGSGTVPFESHIRVLAESLERYAG
                     HAVVAEGRFPARRATWAELSEAGEPTLPLDAFGLFTPEQYARDGFPYQPFTPDAPLDWV
                     RLRSLLGEDDCWVPAQWFLLGHLPDTGELWLQSAVTTGTAAHTDPGRALCAALEEVVQL
                     DSAMGHWHGALRSVRIELDERTRHLTRILEQRFPDTPVDPEFHLLPNADLPGFSVACLL
                     RQPEGLLPRVAIGLGSGARLVPAMYRALLEAAGVQWLAAWVAIEERARGGPSEAADNDF
                     YDLEANVGHYAGAQGSRLVERRFADCDRATAADLPPDTQGTPKEVVRSLVAAFRDSGKR
                     LYWADLSTVDIEDLGFSVQRVWSPDTLSLPLPSAPPAAHRRFEQYGGFRRYDPHPYP*"
     CDS             complement(8789..9825)
                     /protein_domains="TIGR03882"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4221979"
                     /pseudo=False
                     /translation="MASAINPRVRKAFTVIGHSPDVVELRTGVWNPRSFTLTDETEGGK
                     LFNIVSGLDGSLSRRDLAKREGVSRADVEAVVDHLYGLGVIEETPTGALDAYVEQVATI
                     GAAAEAPRFADRLLLLGDPRITEQIEAQSGGALRIPVSRPGAADPLWKRFTELEPAALH
                     DGLDVAALAEEFAPWRDSFAVLAESTIRPLRFRAFNRLAQELNITWIHGALDGPFVFVG
                     PTVVPHRSACWECFETRVTMNLREASSYLTYKNALAKGDVLAGEAPVLPALTGLLASHL
                     GLETVNYLHSGSTFSIDKVLGVYLPTMEIAYNEVLRMPGCRGCAPVPERDDTSLVFDPR
                     TWLDD*"
     CDS             complement(9953..10875)
                     /protein_domains="PF00881"
                     /protein_domains="TIGR03605"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4221980"
                     /pseudo=False
                     /translation="VGDTPVDSDLILSSVASTARRTISPGLAGVGLRTHALRLDNLSSD
                     RFPRPAEEFLLASRLRRCDRETLLSIASYGADCEVVTRSRTDREPEAGADLLPLAPSSP
                     LEAGLTAAVASRRSVRTWSGEPVRQEELAAVVRHAASVTAEGVADLMTGGTVPVALRAA
                     PSAGGLYPVQLWVAVRRVAGMDPGVLRYLPDRDALARHAGPEAVDTLLASFDVQDGTVE
                     LDRAAAVLLLVARPWRAMRKYGPRGMRFVFHEAGAIAQNAHLAVTALGLGAVDFSGFYD
                     DESNNALDIDGVYECLVHTVIVGTPR*"
     CDS             complement(10957..11105)
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_4221981"
                     /pseudo=False
                     /translation="MKLTAKVVTEHRSRSAQPALEAFGAAGNQAVLVPGACCCCSGAVV
                     RPRG*"
     CDS             11493..12733
                     /protein_domains="PF00067"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4221982"
                     /pseudo=False
                     /translation="VPEQPIDVPDLPAPFGAADAADPYPSYDRLRASGGMRRIRIRPGL
                     APWIVSRYEDVREVLGDERLSTDPATTTEEVRAAIRRGRAEEQVALLGRNLLSVDPPDH
                     TRMRRVMSRALTARRAADLEKPVTRLADELLDELGRRSEADLLADYTLPVAVSVVCRII
                     GIPERDHGLFRGWGRALVRAELEDMTAFDRVSDEMAEYFVPFILGKRRSPGDDLVSVLA
                     SARDEERLDDHELISLVYQLFFAGHESSAYFMANAVLTLLRHPAELARLRADPELLPGA
                     IEELLRYEGSVKVPTWRFAKQDLVIAGTAVARGEPVLALLASAGRDPERHPEGAGALRI
                     DRVDTAHLAFSHGIHHCMGAAVGRLESRVAVSRLLDRFPDLRLSVPEDSLRWRVNLMMR
                     GVRELPVTVGRPAL*"
     CDS             12901..13820
                     /protein_domains="PF01435"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4221983"
                     /pseudo=False
                     /translation="MQSRFRNDRRLTMRMGFTMFLLGLLYVGFIAALIVLLKSWLLVVV
                     LIGAMFVAQFWFSDRIAMFAMRGRVVEREEYPELHAVVDRLCAIADMPKPVVAVSDMDM
                     PNAFATGRNPDHAVVCVTTGLLRRLEPAELEGVLAHELSHVAHKDVAVITIASFLGVIA
                     GLIVRFAFYSQLFGGGRRDQNTAVIFAAVMGVSAAVYAISFLLIRALSRYRELAADRAA
                     AHLTGRPSALAAALTKVTGDIARIPTKDLRTAQAFNAFYFTPATGREPGIERYFSTHPT
                     LEQRLDQLGRISTELGEAATPEQAD*"
     CDS             13854..14437
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4221984"
                     /pseudo=False
                     /translation="LGLLDILLGRTKPVAPNLDQLFALPSAAVALEAAAGFTPTGCGAV
                     CFATVEGAAFEQTHREVQALLDADTDRTGPPVELRQDDYGYSWLVSRRAPDQLPQLVND
                     LHAVNSSMEVNGFGPQLLCSLAVFTDDAGRKLALVYLYKRGTYYPFAPLPGTGERRDNA
                     LELRVKAALADDLRIEQDLGRWFPVWGAPGL*"
     CDS             complement(14600..15939)
                     /protein_domains="PF10009"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4221985"
                     /pseudo=False
                     /translation="MSTPEDRAQLGKGARKRVSRSAHGRWLASAERNDPVAVLERQGRD
                     RLPELLAIRYGRMAASPLAFLRGAAAVMAADLAAQPHTGLTVQLCGDAHLLNFGLCASP
                     ERALLFDLNDFDETFPGPFEWDVKRLAASVAVAARENGHSEGEAHAAAQAAVHGYRAAM
                     RRLAGLGELHVWYERVDADSLLPLIRSSRGRRRAESSLTRARRRTSLQALGKLTEVVDG
                     QRRIIHDPPLLEPAGAPDTACLRKIFSDYRSTLSEERRQLLDRYRFVDAARKVVGVGSV
                     GLRCFIVLLAGRDTDDPLFLQIKEARTAVLEEHLPSGPFIHPGHRVVAGQRLLQSASDI
                     FLGWMTGPQGRAFYWRRLRDGRKSADVAGMNPAGLLAYARLCGTTLARAHARSGDRIAI
                     AAYLGGANTFDRAVADFALAYADQTVTDHATLGAAIAAGVVTAAPGV*"
     CDS             16151..16890
                     /protein_domains="PF06224"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4221986"
                     /pseudo=False
                     /translation="VASRRSADEPRLSEQFVYAAGKSYEGLHTVSSRLLRVLGVEGKVV
                     RGRPLGSWTSSRFRWAPAPEHPELDTAEAQARLLGRWLGVCGPATEADLKWWTGWRVTE
                     VRRALAAVGAWEVSLDEGTGYVCADDLAPVPDPGEPWAALLPALDPTAMAWRQRDWYLP
                     AQLRPLLFDRSGNVGPTVWWNGRVVGGWAQRADGEIAWRIPEEAARREAAAAVASAAER
                     LHGWLGTTRVTPRFRTPLERELSA*"
ORIGIN
        1 atgacggaac aggacggctg ggagcggaag ttcgatcacc gctgggcgaa ttccgccgag
       61 cacaaggaac cctcggcccg ggcccggatg ctcgccgcgc gctggaagga gaacccgccg
      121 ggaccggtgc ccttccgcgc cgatcccggt ccggtgccgc gccggtcgtc gtgggcgtcc
      181 acggccgtgg tcctcggctg cgtgatcgtg gtcatggtgc tgatcggaat cgtggagctg
      241 ggctcctccc ggtagggagg acggaccacg cgggacccga cgggggatgc gggtcccgcg
      301 tggcgttctc ggggtgtcac ctcgccgccg cgacctccag cagggactgc ggaggcgtca
      361 ccggggtgac ggacaccagc cgcaggcccg cggagtcgaa cagcgcggtc cactcgtcga
      421 ggcggcgttc ccggcctccg ttgttcacca tgacctcgat gtcgatgaac ttgctccagt
      481 ggtaggaagc gtcgtcgggg acgatcgtgt ccagcaccag gacccgtgcg tccgaccgtc
      541 cgcgcagcgc ctcggcgagc ggccgcagca tggcgcgggc gtccgtgtcg gcgaagcagt
      601 gcagggtgtt cttgagcagg taggcatccg cctcgggggg tgtgctctcg ggcagggtgc
      661 ctgggaagaa ggtgatgcgt tcgtacgccg gggtgccggc cagggcggct cgggccgcct
      721 ccagtacctc cgggcggtcc atcagcacgc ctcgcgcggc gggggccgcg ccgagcaggt
      781 ggtacagcat ccgcccgtgg ccaccgccga tgtccgcgat caccgggtac cggccgaagt
      841 cataggcttc ggccgcttcc ggggccagtt cgtcggtgag actggcccac gcgccctggt
      901 atgcgcgggc gaggtccggg tggtcggcca ggtaggtgaa gagatcggtt ccgtgcacct
      961 gcgggaagga cggcgcaccg gtgcgcacgg tgtgcatgat cgcgccgaac gaagcccagg
     1021 tcggctccga tccgagcagg atggtgaagt cccggatgct gcacggcacg tcggaacgga
     1081 gcgcttcccc catggggcgc agcgagaaac ggcctcccgg ttcctcggcc aggacgccga
     1141 gcgcggccgc gacacgcatg cagcggccca gtgcgtccgg gtgcacttcc aggaccacgg
     1201 cgagctcggc ggccgttcgg ggcttgtcgg cgagcaggtc ggcgacgccg agttcggcca
     1261 ggacgtagag gggctgggac atccacttgc cggcgaccaa acccatcagc tgtacgtgcg
     1321 gcggcagttg cggtgcggcg gccatcgacc ccactccctc cttaacggcg ttaggtgtac
     1381 tctaacggtg ttagggaaac ggtgcaggcg gaatctcgcc aaaaggcggg cactccgcgg
     1441 cgcgaggcac gaggcgtccg cagcggacgc cgaaggaggt gtccgggcaa tgcgagctcc
     1501 atggaagggc gatcccgccg aacgggcgcg ccagcgcgct gcgcaggtcg aaaagcagcg
     1561 cgaacaggcc cgcaggcagg aggaccaacg gctcgcgcag gaactgcgcg agcaacagcg
     1621 cgcggcggaa gaacgcgagc gcgaggcacg gcgagccgaa cgggacggtc ggtgacgctc
     1681 ctcccgccgc atccggtgcg ggaggagcgg gccggctcag cgcacgtagg ccgtcagccc
     1741 gtcgatgagc cggtccagac cgaaccggaa ccgctcgtcg aggttggcct cggtgagcgc
     1801 gtcgacggac tccgcgaggt acgggaactc atcgtgcggc agcgccccga tcgccgcctt
     1861 caccccgcgc agcgcgtcgg agcgctccat gccctcggcg ttggaggcgg acagcgggga
     1921 actctcgtgc aggacgaagc cctgcacgta gacgatgatc gtgtagacgg cgtaggcggc
     1981 gtcgtgggac gacaggccgc ccgcgcggag cacgccgagg atcggctcca gcagccgggc
     2041 cagcgagacg ccaccgacga accggccggc gatgatgcgc gccgcgtcac ggcgacaccg
     2101 caggaaggcg cggtagttca cggcggtctc gcgcagggcg tccgtccagg ccttctcacc
     2161 ggtggccaca cggtccaggt cggccggcag ggcctcggtc aggacccggg tcagcagctc
     2221 gtccgccagc agatcgagca cctgctcctt gctctgcacg tgccagtaca gcgacgcggc
     2281 ctgtacaccg agctgctcgg ccagccgccg catcgacagg gcgtccaacc cctcgctctc
     2341 caccacgtcg agggccgcgg ccacgagggc cgacctggtc acagaggggc ggcgcccggc
     2401 cggagctgcc gccctgggcc gacgcaccgt cattcgtcca cctccgtcag cggcttgaaa
     2461 catagcacgc ccctcaccga ccacctgtaa cgggcggtgc ccgtcccgcc cgaccgatga
     2521 ggagtcccgc catgagttca ctgccgagcc ccgcgccgtc agctgtgcgc cgccggctca
     2581 ttctgctcac cctgtgcgtg tccttgttca tggccatgct ggacaacacg gtggtgaaca
     2641 ccgcgctgcc gaccatcgaa cggaagctcg gagcgggcat cagcgatctg cagtggatcg
     2701 tcgacggcta cagcctcgca ctctccgctc tcatgctgac cgccagcacg gtcggggaca
     2761 tgttcggtcg acgccgggcg ttcgtggcgg ggctcgccct cttcgcggtc gggtcgacgg
     2821 tgtgtgcgct gtcacgggac gtgaacgtcc tgatcagcgg acgggtgctg cagggcgccg
     2881 gtgccgcggc cttcatgccc ggcacgctgt cgatcatccg gcaggtgtat gccgacgaac
     2941 gggaacggag tacggccatc gggatctggg cgggcgtgtc ggggctcggc ctggggctcg
     3001 gcccgctggt cggcgggccc ctggtggacc acttcggctg gccgagcgtg ttctggatca
     3061 acgtaccggt gggcatggcc gggctgatcg ccgggatgct gctcatcccg gagtccaagg
     3121 accgggcggg ccgcggcctg gacatcacgg gccagctgct ggcggtggcc ggcatcggcg
     3181 ccggggtgta tgccacgatc gagggcccgg tacgcggctg gtcggacccg gcggtcaccg
     3241 gcctgtacat cggcgcgggt gtggtgctgc tgctcttcgt gctggtcgag cgccgcagcc
     3301 ggacaccgat gctggacctc ggcttcttcc gggaccggat cttcgcgggc tcggtgctcg
     3361 ccgggctctt cctctacctc ggcatgttct cggtgctgta cttcctcagc ctgtggctcc
     3421 aggtggtgct cggctggtcg cccaccggag cgggactcgt gatcatgccg gccatggtgg
     3481 tggtcgcctg cgtgaccccc ctggcgggct ggctgaccgg gcggatcggc ggcggctggc
     3541 ccatggcggc cggcctggtc tgctcggcct tcgcgctcta cggcctgacc cggtacggca
     3601 ccggtgcctc ctaccggcac ttctggtggc tgctgccggt gatcggcatg ggcatggggc
     3661 tcaccatcac tccgatcacg gccaccgtcc tggaccgggt cccggcggcc cgggccggca
     3721 tggcctcggc agtcagcaac accgcccggg aactgggcgg ggtgctcggc gtggcggtgc
     3781 tcggctcggt gctgagcagc cggatggcgg agcggctccg ggagcggctc acggccgcgg
     3841 gcgtgccggc gtccgaacgg gaccggctgg tcgcggccac gaccggcggc accggacgac
     3901 cgcaggccgg gctcggcgcg ggagcccggc tgtcgcacgc ggtgaacggc gccttcgtgg
     3961 acgggttgca cctggccgaa ctgtcgggtt gcgcgatcct gctggccggc gccctgctgg
     4021 cggtggccct ggtgcgcggc ggccggggcc cggctccggg gtcccgcggt ggcaagtcgg
     4081 gagagctcga cacctccgac gcgcacgacg acaccgacgg ccgcgccacg gtggccacct
     4141 gagtgggccc cggccgtgcc caccgtgggc ggtcacggca acttgggcag cacccggtcg
     4201 acgaagaggc gcaggctgga ctccatgctt gcgtagtcct gaccgccgta gtcgacctgc
     4261 cacaggaagg tgtcggcgct caggtactcg cccagttcga ggatccggtc gaccacccgc
     4321 tgcggggagc cgacgatcgc ggtgcccacg ctgcggaagt cgtcgatgcg caggttccgc
     4381 agggagagcg ccatctgact gtaggccgga tagtccgacg aggacacccc cgtccagtcc
     4441 tcggcggact cggcccacac gttgaggtac tcgcgcagga acgggtcggc cgtggcgaat
     4501 gcctgttcgt ccgtctcggc cacgtacagc gggatgctga ccgccacctt gggctggcgg
     4561 tccgtgcccg cgtgttcctc gcggaaggtg tccaggtaca cctccaccat gtccttggtg
     4621 cgggcgagtt cctcgcggcg cggcggcgga gtgacgaaga gcccgtgtcc ggcctcaccg
     4681 atccaggcga agctctgccg ggagcgcacc gcggcgcacc acaccggagg atgcggcgcc
     4741 tgggtcgggc ggggcaggga ggtggcgtcg cggtaggaga agaagggggt gtcctcggcg
     4801 accttctcct ccgtccacag gcgcagcacg gcctcgatgg tggcctggaa ccgggcccga
     4861 ctctcgtcca gcgggacgcc gaaggccgcg aactcgtacg gcagccaggc gcgggcgaag
     4921 ccgacctcga gacggccgcc gctgagcgcg tccaccatcg ccgtgtgtgc ggcgagttgc
     4981 acggggtggt ggaaggcagc ctggagacag ccggtcatga gccggatccg ggacgtactc
     5041 gccgcgaccg cggacaggaa ggacagcggg tcggggcagt agccgccgta gtcgcgcagg
     5101 tagtgctcgg tcatcttgac gtagtcgatg ccggccgcgt cggcgaaccg gctcagggcg
     5161 agtacgtcgc ggaagtaggc gttggcggac cggcgggcgg gccggcagtc cggcagcagc
     5221 gagattccgt gcttcatgcg cacctcacgg gttggagagg gggttcggtc aggcaccggc
     5281 aaggaggaag aaggaccact gcgcggcggc ggacgcgagg acgtccggcg tgtgcaggaa
     5341 cagcagggag ttgacggtgg cgatcacggc gacgccggtg accgccgcgg gaccggaccg
     5401 gcggacggcc ggcagcgagc cgacgagcag cgttgccacg gccgcggcca gcaagccggc
     5461 cacggcacca agtggcttca gggcgaggac cagtccgccg cgcagagcca gttcctcgac
     5521 aagcggctgg gcggccagca cggccaccag agctggccag ggcagggtcc cggccagccc
     5581 ccgcacccga ccggcccacg aggtgcgagc cagtcctagc cagttgctgc ccccggaact
     5641 ggcggaagcc atgacgcgtc ccgcggacgg gctccggccg cggccctcgg caccgccccc
     5701 ggcagcaaga gctccggacc ccggagcggg cccgaggggc gcgcgaccct cggcaccggc
     5761 tcggaagggg cgtcggacgc cgggaccgac accggagccg gaggggcgtc cggagccggg
     5821 accggcgccg tcgtcgcccg cggatccggg cggggaggcg gccccggaac ggggtcccag
     5881 gcgcccggac caagacggtg cacgggtgcc gctgcccgat cgaggcccgc cgcgcgcggt
     5941 cccggctcgc cccggcatgc gtgggcgcct ccgcacacgc gcgcgcagca gggccacagc
     6001 gtccgcggtg accactgcga ggagacaggc ggcagcgaac tcgccggtgc cgagcagcag
     6061 tccggcgggg acgagaagca ggtcggcccg ggagcaggcc agggtgtgga gcaaccgtcc
     6121 gggtcccggg gccacgaagc caagggcgcc ggcaccgagg agcatcagga ccgcagcgcc
     6181 ggccgtgcac gtggcccaca gcgcgtccac gacctcccgg ccggtgcgcg gggcgcggat
     6241 ccggcagcgc agacggccgg ccagcagata cccggcggtg accgtcgcga cgccgatgag
     6301 cccgccggtc acgccgccgg tcaccgcggg ccccctggct cggccgccgg gctcgtcacc
     6361 ggcgcgagag acgcccgggt cccggccccc accgaggccg cgcgcgcacg cgcgcggctc
     6421 cgcggctcgg ccgggacagc ggtcccggcc ggtcccggca cggcggtggg cgccccggca
     6481 ccgatctccc ccacggcgcg gcgcggcggg gaccctgtcc cggagcgggg gaggaaaccg
     6541 gcccagcccc ccggcggcac gtcgaccgtg ccggaaccgg tcaccgcccg cgccggccgc
     6601 aggccgacgc cgtctccagc cactaccggc gccgcgcccg cgccgtgggc ccgggtcatc
     6661 gggttgctcc cggttggacg acgaccgggc ggtgacgcca gacgtgccag ttgaacaggg
     6721 cgtgccccag ggcggcggcg aggaccgtgc cgagtgcgag ggtcgccacc gtggcgagga
     6781 cggaaagcgg cagtttggcc aggacctggc gccagccgaa gaacacgtgc gacagggcga
     6841 aggccgccac cgccgcgacc actcccgtcg cgcgggcgac tggggtgtcc agttgcacgg
     6901 ccagccgcag cagcacgccc cggaagacgc actcctcggc gaccgcggtg gccaggagcc
     6961 agccgagggc gaggttcaga tccgtgtcgc ggcgggtggg tgtccacctc cggtcggcgc
     7021 ccgtgtgcgc ggccgaccgg aggggagcca ccgtgccgcc cagcccgacc ggccgcagcc
     7081 ggcccggtgc cgccccctcc ccggaggccg gcgtgcgcgc caccgcgggc gggcggcggg
     7141 ccgccgtccg gctgatccag ccgtcggccc gcacgaccac ggccccgagc agcagtcccg
     7201 cgccgacggc cgccaccgcg cgggcggccc ctggcccgcc ccgccacagc catcccggcc
     7261 cgagcaggag cagcccgcag cccgccgtga cggcgagcac ggacacgtgc accggcacca
     7321 tccgcacccc acgcgcgtcc agccggcgca catggagatg cgaggcgagg gtcgtcccgg
     7381 aggcggcggt cagggccagc caggccagcg cccacagccg tgcgtcatgg gtagggatgg
     7441 gggtcatacc gccggaatcc tccgtactgc tcgaaacggc ggtgggccgc cgggggcgcg
     7501 ctgggcagtg gcaggctgag cgtgtccggc gaccagaccc gctgcacgct gaagccgagg
     7561 tcctcgatat ccacggtcga caggtcggcc cagtacaggc gcttgcccga atcccggaag
     7621 gccgcgacca gggaccgtac gacctccttc ggcgtgccct gggtgtccgg gggcaggtcg
     7681 gcggcggtcg cccggtcgca gtcagcgaac cggcgttcga ccaggcggct tccctgggct
     7741 cccgcgtagt ggccgacgtt ggcctccagg tcgtagaagt cgttgtcggc cgcctcgctg
     7801 gggccgcccc gggcgcgctc ctcgatggcc acccaggcag cgagccactg cacgcccgcg
     7861 gcttccagca gcgcccggta catcgcgggc accagccggg ctccgctgcc caggccgatg
     7921 gcgacgcggg gcagcagtcc ctccggctgg cgcagtaggc aggccacgct gaagccgggc
     7981 aggtccgcgt tgggcaacag gtggaactcg gggtcgaccg gggtgtccgg gaagcgctgc
     8041 tccaggatgc gggtcaggtg gcgggtccgt tcgtccagtt cgatgcgtac gctgcgcagg
     8101 gcgccgtgcc agtggcccat cgcggagtcg agctggacga cctcctccag cgcggcgcac
     8161 agggcgcggc cggggtcggt gtgggcggcg gtcccggtgg tgacggccga ctgcagccac
     8221 agttcgccgg tgtccgggag gtggccgagc aggaaccact gggcgggcac ccagcagtcg
     8281 tcctcgccca gcagggacct cagccgcacc cagtccaggg gcgcgtcggg ggtgaacggc
     8341 tggtagggga agccgtcgcg ggcgtactgc tcgggggtga acaggccgaa cgcgtcgaga
     8401 ggcagggtgg gttcgccggc ctcggacagc tccgcccagg tggcccggcg ggccgggaac
     8461 cggccttcgg cgaccacggc gtggccggcg taccgttcca gggactcggc gagcacccgg
     8521 atgtggcttt cgaacggtac ggtgcccgag ccgcccagat ggaagctgcc gggtttgggt
     8581 gcgggccggc cctgcaggac gtggacgccg gccaggtcac cgctggcgat caacatgcgg
     8641 gggccggtgc gggtgcggct gaggaagccc atcgaggtga gcaccccgca caacgggctg
     8701 tgcatccggg agcgcagggc cgtggcccgc tcgtcctcgt cgcgcagcag ccgcaggtca
     8761 agggccaccg gttcggtgct cagggtgtca gtcatccagc cacgtcctcg ggtcgaagac
     8821 gaggctcgtg tcgtcacgct cgggcaccgg ggcgcagccg cggcagccgg gcatgcgcag
     8881 cacctcgttg taggcgatct ccatcgtcgg caggtagacg ccgaggacct tgtcgatgct
     8941 gaaggtgctg ccggagtgca ggtagttgac ggtctccagg cccaggtggg aggcgagcag
     9001 accggtgagc gcaggcagca cgggcgcctc gccggccagg acgtcaccct tggcaagggc
     9061 gttcttgtag gtcaggtagg aggacgcctc gcgcaggttc atggtgaccc gggtctcgaa
     9121 acactcccag caggccgagc ggtgcgggac gacggtgggg ccgacgaaga cgaagggccc
     9181 gtcgagtgca ccgtggatcc aggtgatgtt cagctcctgg gcgagccggt tgaacgcgcg
     9241 gaacctgagg ggccggatgg tgctctcggc gaggacggcg aaggagtctc gccagggggc
     9301 gaactcctcg gccagggcgg cgacgtcgag cccgtcgtgg agggcggcgg gctccaactc
     9361 ggtgaagcgt ttccacagcg ggtcggcggc gccgggccgg ctgaccggaa tgcgcagcgc
     9421 accgccggac tgggcctcga tctgctcggt gatccggggg tcaccgagca gcagcagccg
     9481 gtcggcgaag cggggtgcct cggccgcggc accgatggtc gccacctgct ccacataagc
     9541 gtcgagggcg ccggtcggcg tctcctcgat aacaccgagg ccgtagaggt gatcgacgac
     9601 cgcctccaca tcggcacggc tgacgccttc acgtttggcc agatctcgac gactgagcga
     9661 gccatccagg cccgagacga tgttgaagag ttttcccccc tcggtctcgt cagtgagcgt
     9721 gaatgatctc ggattccaca cgccggtccg caattccacg acgtcggggc tgtgcccgat
     9781 gaccgtgaac gcttttcgga cacgcgggtt tattgcgctt gccattcctt ctccccgatg
     9841 catcggaaca gtacggcacc gccctgccgg agtcgcgttc cgcaagaaga tggaaagtgg
     9901 cagcgcggaa caggcagacg tgccgaaatc cggaagtctt taccgaaccc gtcagcgcgg
     9961 agtacccacg atcacggtat gcactaggca ttcatagacg ccgtcaatat cgagcgcatt
    10021 gttggactcg tcgtcgtaga agcccgagaa gtccacggcg ccgaggccga gggccgtgac
    10081 ggcgaggtgc gcgttctggg cgatcgcacc ggcctcgtgg aagacgaagc gcataccgcg
    10141 cgggccgtac ttgcgcatgg cccgccaggg ccgggcgacc agcagcagca cggcggcggc
    10201 gcgatcgagt tccacggtgc cgtcctgcac gtcgaaggag gcgagcaggg tgtcgacggc
    10261 ctcgggaccg gcgtgccgag caagggcgtc acggtccggg aggtagcgca ggacgccggg
    10321 gtccatgccg gccacccgcc gcacggccac ccacagctgt acggggtaca ggccaccggc
    10381 gctcggtgcg gcgcgcaggg ccaccggcac cgtgccgccg gtcatcaggt cggcgacgcc
    10441 ctcggcggtc acggaggcgg cgtgacgcac cacggcggcc agttcctcct gccgcacggg
    10501 ctcgcccgac caggtgcgca cgctgcgccg ggaggcgaca gccgcggtca gaccggcctc
    10561 cagcgggctg gacggggcaa ggggcagcag gtcggcgccg gcctcgggtt cgcggtcggt
    10621 gcgggagcgg gtgacgacct cgcagtcggc gccgtaggag gcgatggaca gcagggtctc
    10681 gcggtcgcag cggcgcagcc gggaggcgag caggaactcc tcggcggggc gtggaaaccg
    10741 gtcggaggag aggttgtcca ggcgtaacgc gtgggtgcgc agacccactc cggccaggcc
    10801 cggactgatc gtgcggcgcg cggtggacgc cacggaggac aggatgaggt cggagtcgac
    10861 tggggtgtcg cccactggcg ggaatccctt cttcacgccc tgggtggagc cgggcgggcc
    10921 gcatgcggcc cgacccgacc ccagggctgc ggatgtcagc cgcgcgggcg gacgacggca
    10981 ccggagcagc agcagcacgc accgggcacg agaacggcct ggttgccggc cgcgccgaac
    11041 gcctcaaggg ccggctgcgc ggaacggctg cggtgctcgg tgacgacctt cgccgtgagc
    11101 ttcatgatga cctccgaatt ctggacgaca ggtttgctgt acaggcccgg gaagatcggg
    11161 cttccggctg gaggatcact tgctggcgga acggaccctt caggaaaacc gcgttcccgg
    11221 ccgtcacaac gtgggccctt cggtgtgacg cgacgaacct aacaccattt ggctggaacc
    11281 agtcaacccc caatcgatga acaagatgag ggaccgcgca atactctgga aacacaccaa
    11341 taaaccggat ggccgccctc cgatttacct gacggcaaca aataagcagg agcagctctt
    11401 ttctgtttct tttacctcct tttccttgtt gtaccgggcg ggccgccttt agtttctggt
    11461 ggcctgcggt ggacgcggag aaggagatga cgtgcccgag cagccgatcg acgtacccga
    11521 cctgcccgcc cccttcggcg ccgccgacgc ggccgacccg tacccgtcgt acgaccggct
    11581 gcgcgcgtcg ggcggcatgc ggaggatccg gatccggccg gggctcgcac cctggatcgt
    11641 ctcccggtac gaggacgtgc gcgaggtgct cggagacgaa cgactgagca cagatccggc
    11701 caccaccacc gaggaggtgc gcgccgccat ccggagaggc cgggcggagg agcaggtcgc
    11761 cctgctcggg cgcaacctgc tcagcgtgga cccgccggac cacacgcgga tgcgccgcgt
    11821 gatgtcccgc gcgctcaccg cccggcgcgc cgccgatctg gagaaacccg tcacccggct
    11881 ggccgacgaa ctcctcgacg agctcggacg acgcagcgag gcggacctcc tggccgacta
    11941 cacgctgccg gtcgccgtga gcgtcgtctg ccggatcatc gggatacccg agcgggacca
    12001 cggactcttc cggggctggg ggcgggccct ggtgcgcgcc gaactggagg acatgaccgc
    12061 gttcgaccgc gtcagcgacg agatggcgga gtacttcgtc ccgttcatcc tcggcaagcg
    12121 gcgctccccc ggcgacgacc tggtcagcgt gctggcctcg gcgcgggacg aggagcggct
    12181 cgacgaccac gagctgatct ccctcgtcta ccaactcttc ttcgccgggc acgagagcag
    12241 cgcctacttc atggccaacg ccgtgctcac gctgctgcgg catcccgccg agctcgcccg
    12301 actgcgcgcg gacccggaac tactgcccgg ggcgatcgag gagctgctgc gctacgaggg
    12361 ctcggtcaag gtgccgacct ggcgtttcgc caaacaggac ctggtgatcg cgggtacggc
    12421 cgtcgccagg ggcgaaccgg tcctggccct cctggcgtcc gcgggccgcg accccgagcg
    12481 ccaccccgag ggtgccggcg cgctgcgcat cgaccgtgtc gacaccgcac acctggcctt
    12541 cagccatggc atccaccact gcatgggtgc cgcggtcggc agactggagt cccgggtcgc
    12601 cgtctcccgg ctgctcgacc gcttcccgga cctgcggctg tccgtgccgg aagactcgct
    12661 gcgctggcgg gtcaacctga tgatgcgggg tgtccgcgag ctcccggtca ccgtgggcag
    12721 gccggcgctc tgaccgcttc ccccagcgga tcagcgccct gacccggtca ccggccgtcc
    12781 ccggatcccg accctcaggt acgttttgcc gcgcctaggg ccgttcggga cctcctcatg
    12841 ggacgcggca ggtgcacact ggacaccggg aagagagcct gactgcgggg tgatgcaaga
    12901 tgcagagccg cttccggaac gaccggcggc tgaccatgcg tatgggtttc acgatgtttc
    12961 tgctcgggtt gctgtacgtg gggttcatcg cggcgttgat cgtgctgctg aagtcgtggc
    13021 tgctggtcgt cgtcctgatc ggcgcgatgt tcgtggcgca gttctggttc tccgaccgga
    13081 tcgccatgtt tgcgatgcgc gggcgggtcg tggagcggga agagtatccc gagctgcacg
    13141 cggtggtgga ccggctgtgc gcgatcgcgg acatgccgaa gccggtggtc gccgtttcag
    13201 acatggacat gccgaacgcc ttcgcgaccg gacgcaaccc cgatcacgcc gtggtctgcg
    13261 tgaccaccgg actgctgcgc cgactggagc ccgccgagct ggagggcgtg ctggcgcacg
    13321 agctgtcgca cgtggcgcac aaggacgtcg ccgtgatcac catcgcatcg ttcctcgggg
    13381 taatcgccgg gctgatcgta cggttcgcct tctactcgca gctcttcggc ggcggccgca
    13441 gggaccagaa caccgccgtc atcttcgccg cggtgatggg agtctcggcg gccgtgtacg
    13501 cgatcagctt cctcctgatc cgggccctgt cccggtaccg ggaactggca gccgaccggg
    13561 ccgccgcgca tctgaccggc cggccctccg cgctcgcggc ggcgctcacc aaggtcacgg
    13621 gggacatcgc ccgtattccg accaaggacc tgcgcacggc ccaggcgttc aacgcgttct
    13681 atttcacccc ggcgaccggc agggaacccg gcatcgagcg ctacttctcc acccatccga
    13741 ccctggagca gcggctggac cagctgggcc ggatctcgac ggagctgggc gaggccgcca
    13801 ccccggagca ggcggactga ggaccatgga actgcggaag gcggactgag cgttgggcct
    13861 gctggacatt ctgctggggc gtacgaagcc ggtcgcgccc aatctcgacc agttgttcgc
    13921 gctgccctca gctgcggtcg ccctggaggc ggcggccgga ttcacaccga ccggatgcgg
    13981 agcggtgtgc ttcgccacgg tggagggcgc ggccttcgag cagacccatc gggaggtaca
    14041 ggccctgctg gatgcggaca ccgaccgcac cggccctccg gtggagctgc gacaggacga
    14101 ctacggatac tcctggctgg tgtcccggcg ggctcccgac cagctcccgc agctcgtcaa
    14161 cgacctgcac gcggtgaaca gctccatgga ggtcaacggc ttcggaccgc agctgctgtg
    14221 ctccctggcg gtgttcacgg acgacgccgg gcggaagctg gccctggtct atctctacaa
    14281 gcgcggcacc tattacccgt tcgcgcccct gcccggtacc ggcgagcggc gggacaacgc
    14341 gctggagctg cgggtgaagg cggccctcgc ggacgacctg cggatcgagc aggacctcgg
    14401 ccgctggttc ccggtgtggg gcgcacccgg cctgtgactc ggggggctct ggcccaccgg
    14461 ttctcctccc gccctgacgc cggcccggca cctggccccg aagggcgttc ccccggtctg
    14521 ccgcccggta ccggcgcccg cggggtacgc ccggtggtgc tcgttcaagc gcctccgcac
    14581 ccggtgaccg gcagccggtc acactccggg cgcggccgtc accacacccg ccgcgatggc
    14641 cgcgcccagg gtggcgtggt cggtgacggt ctggtcggcg taggcgaggg cgaagtcggc
    14701 gacggcccgg tcgaaggtgt tggcgccgcc gaggtaggcg gcgatggcga tgcggtcgcc
    14761 ggagcgggcg tgggcccgcg cgagggtggt accgcacagg cgggcgtagg cgaggagccc
    14821 tgcggggttc atgccggcga cgtccgccga tttcctcccg tcacgcagtc ggcgccagta
    14881 gaaggcacgg ccctgcggtc ccgtcatcca gcccaggaag atgtccgagg cggactgcag
    14941 cagccgctgc ccggcgacga cccggtgccc ggggtggatg aacggcccgc tcggcaggtg
    15001 ttcctccagc accgccgtgc gcgcctcctt gatctgcagg aacagcgggt cgtcggtgtc
    15061 gcgcccggcg agcagcacga tgaaacagcg caggccgacg ctgccgacgc cgacgacctt
    15121 gcgggcggcg tcgacgaagc ggtagcggtc gagcagctgg cggcgctcct cggagagggt
    15181 ggaacgatag tcactgaaga tcttccgtag gcaggccgtg tcgggagcac cggcgggttc
    15241 gaggagcggc gggtcgtgga tgattcggcg ctggccgtcg acgacctcgg tcagcttgcc
    15301 gagggcctgg aggctggtgc ggcgacgggc acgggtgagg ctggactcgg ctcggcgccg
    15361 gccgcgcgac gaccggatga ggggcagcag gctgtcggcg tcgacccgct cgtaccagac
    15421 gtgcagttca ccgagcccgg ccagccgccg catggcggcg cggtagccgt gcacggcggc
    15481 ctgcgctgcc gcgtgtgcct cgccctcgct gtgcccgttc tcccgggcgg cgacggcgac
    15541 gctggccgcg aggcgtttga cgtcccattc gaagggaccg gggaaggttt cgtcgaagtc
    15601 gttgaggtcg aagagcagag cgcgttccgg ggaggcacac agcccgaagt tcaacaggtg
    15661 ggcgtcaccg cagagctgca cggtcagacc ggtgtgcggc tgggcggcca ggtcggcggc
    15721 catcacggcg gcggcaccgc gcaggaaggc gagcggtgag gcggccatcc tgccgtacct
    15781 gatcgccagc aactcgggca accggtcgcg tccctgccgc tccagcaccg cgacgggatc
    15841 gttccgctcg gcggacgcga gccagcggcc gtgcgcggag cgcgagacgc gcttgcgggc
    15901 gcctttgccg agttgggccc ggtcctctgg ggtgctcata cggcggcctc tttccggatc
    15961 gctcccgtca cctcctgatc gcagtcaagg acaggtgggc gccacggcgc atgcgcagtc
    16021 cggcgaacgg gtgacgggaa caacgggtga cggagcccgg gaggggcacg gagacgaacg
    16081 cggacctggg cgaaggcctg agccgggacc gatagtcagt ggcgtcggcg accatgctga
    16141 caggatgtgg tggcatcgag gaggtcggcg gacgagcccc ggttgagcga gcagttcgtg
    16201 tacgcggctg ggaagagcta cgagggcctg cacacggtct cctcccgcct gctgcgggtg
    16261 ctcggtgtcg aaggcaaggt ggtccggggc cgcccgctcg gctcctggac gtccagccgg
    16321 ttccgctggg cacctgcgcc cgagcacccg gaactggaca ccgccgaggc ccaggcgcgg
    16381 ctgctgggcc gctggctggg ggtgtgcggc ccggcgacgg aggcggacct gaagtggtgg
    16441 acgggctggc gggtgaccga ggtacgccgg gccctggcag cggtcggagc gtgggaggtt
    16501 tccctggacg agggcaccgg gtacgtctgc gcggacgacc tggccccggt cccggacccg
    16561 ggggaaccct gggcggccct gctcccggcc ctcgacccga cggcgatggc ctggcggcag
    16621 cgggactggt acctccccgc gcagctgcgc ccgctcctct tcgaccgcag cggcaacgtg
    16681 ggaccgacgg tgtggtggaa cggccgggtg gtgggcggct gggcacagcg cgcggacggc
    16741 gagatcgcgt ggcggatccc cgaggaggcc gcacggcgag aggctgctgc ggcggtggcg
    16801 tcggcggctg aacggttgca cgggtggctg gggacgaccc gggtgacgcc gcggttccgg
    16861 acgccgctgg aacgggagct gtccgcttga
//
