LOCUS       LN831790               27291 bp    DNA     linear   BCT 17-JUN-2020
DEFINITION  Streptomyces leeuwenhoekii strain C34 (= DSM 42122 = NRRL B-24963)
            genome assembly, chromosome: chromosome.
ACCESSION   LN831790
VERSION     LN831790.1
KEYWORDS    .
SOURCE      Streptomyces leeuwenhoekii
  ORGANISM  Streptomyces leeuwenhoekii
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-02-26 04:50:55
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 3666108
            Orig. end    :: 3693399
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     cand_cluster    1..27291
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="Trp_halogenase"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="neighbouring"
                     /product="halogenated"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..27291
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="halogenated"
                     /product="RiPP-like"
                     /region_number="28"
                     /rules="Trp_halogenase"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     protocluster    1..21284
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11284]"
                     /cutoff="5000"
                     /detection_rule="Trp_halogenase"
                     /neighbourhood="10000"
                     /product="halogenated"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11284
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="Trp_halogenase"
                     /neighbourhood="10000"
                     /product="halogenated"
                     /protocluster_number="1"
     cand_cluster    1..21284
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="Trp_halogenase"
                     /kind="single"
                     /product="halogenated"
                     /protoclusters="1"
                     /tool="antismash"
     gene            complement(411..2915)
                     /gene="sle_30640"
     CDS             complement(411..2915)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VRX3"
                     /db_xref="InterPro:IPR000283"
                     /db_xref="InterPro:IPR001041"
                     /db_xref="InterPro:IPR006656"
                     /db_xref="InterPro:IPR006657"
                     /db_xref="InterPro:IPR006963"
                     /db_xref="InterPro:IPR009010"
                     /db_xref="InterPro:IPR010228"
                     /db_xref="InterPro:IPR019574"
                     /db_xref="InterPro:IPR036010"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VRX3"
                     /gene="sle_30640"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134:flavodoxin (Score: 125.5; E-value: 3.4e-38)"
                     /gene_kind="biosynthetic-additional"
                     /product="NADH-quinone oxidoreductase subunit G"
                     /protein_id="CQR62525.1"
                     /sec_met_domain="Fer2_4 (E-value: 3.4e-19, bitscore: 67.3,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVTTSAPSSGGEAARPPEDLVTLTIDGIEISVPKGTLVIRAAEQ
                     LGIEIPRFCDHPLLDPAGACRQCIVEVEGQRKPMASCTITCTDGMVVKTHLTSPVAEKA
                     QKGVMELLLINHPLDCPVCDKGGECPLQNQAMSHGNAESRFEGRKRTYEKPVPISTQVL
                     LDRERCVLCARCTRFSNQIAGDPMIELVERGALQQVGTGEGDPFESYFSGNTIQICPVG
                     ALTSAAYRFRSRPFDLVSSPSVCEHCSGGCATRTDHRRGKVMRRLAAHDPEVNEEWICD
                     KGRFAFRYAQQRDRLRTPLVRNAEGELEPASWPDALQIAAQGLLASRGRTGVLTGGRLT
                     VEDAYAYSKFARVALDTNDIDFRARVHSGEEADFLAARVAGRGRDLDGAGVTYTALEKA
                     PAVLLAGFEAEEEAPGVFLRLRKAWRGHGQQVFALATHATRGLEKAGGTLLPAAPGTET
                     EWLDALAAGVGLDEDGSRAAEALRAEGAVIVVGERLAGVAGGLTAAVRAAAATGAHLAW
                     IPRRAGERGAVEAGALPSLLPGGRPATDPRAREEVAAVWGVAGLPHRYGRDTGQIIEAA
                     ATGELQALLVAGVEVADLPDPARARAALAEAGFLVSLELRPSEVSALADVVLPVAAVAE
                     KAGTFLNWEGRVRLFEAALKPDQMAHRLPPTDARVLQMLADAMDVHLGLPDLRTVRAEL
                     DRLGVWDGPRATEPLETAGPLPRPAAGEAVLAGHRLLLDQGLLQQGDEALAGTRHAAHA
                     RVSPATAAEVGVEDGDVLAVTGPAGSVALPLRVTEMPDRVVWLPLNSTGGGVAADTGAL
                     PGSLVRIGPAKSAAEAPQEVEA"
     gene            complement(2912..4261)
                     /gene="sle_30650"
     CDS             complement(2912..4261)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W0N4"
                     /db_xref="InterPro:IPR001949"
                     /db_xref="InterPro:IPR011537"
                     /db_xref="InterPro:IPR011538"
                     /db_xref="InterPro:IPR019554"
                     /db_xref="InterPro:IPR019575"
                     /db_xref="InterPro:IPR037207"
                     /db_xref="InterPro:IPR037225"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W0N4"
                     /gene="sle_30650"
                     /product="NADH-quinone oxidoreductase subunit F"
                     /protein_id="CQR62526.1"
                     /transl_table=11
                     /translation="MTVATEIKDTSPEKLLAPVLSAFWDEERSWTLDVYRRHEGYEGLR
                     KALAMSPDDVIAYVKDSGLRGRGGAGFPTGMKWQFIPQGDGKPHYLVVNADESEPGTCK
                     DIPLLFANPHSLIEGIVIACYAIRSSHAFIYLRGEVVPVLRRLHEAVREAYAAGYLGTD
                     ILGSGLDLELTVHAGAGAYICGEETALLDSLEGRRGQPRLRPPFPAVAGLYACPTVVNN
                     VESIASVPAIMHRGKEWFRSMGSEKSPGFTLYSLSGHVASPGQYEAPLGITLRQLLEMS
                     GGMRPGHRLKFWTPGGSSTPMFTDEHLDVPLDYEAVGAAGSMLGTKALQCFDETTCVVR
                     AVTRWTEFYAHESCGKCTPCREGTYWLVQLLRDIEAGKGVMSDLDKLNDIADNINGKSF
                     CALGDGAASPIFSSLKYFREEYEEHITGRGCPFDPAKSTAWADHRTEVNA"
     gene            complement(4261..5121)
                     /gene="sle_30660"
     CDS             complement(4261..5121)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VYD0"
                     /db_xref="InterPro:IPR002023"
                     /db_xref="InterPro:IPR036249"
                     /db_xref="InterPro:IPR041921"
                     /db_xref="InterPro:IPR042128"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VYD0"
                     /gene="sle_30660"
                     /product="NADH-quinone oxidoreductase subunit E"
                     /protein_id="CQR62527.1"
                     /transl_table=11
                     /translation="MTTSSSERGVSLGMPELPAPEYPDDVRARLEADAREVIARYPDSR
                     SALLPLLHLVQSEEGHVTRTGMRFCADMLGLTTAEVTAVATFYTMYRRRPSGDYQVGVC
                     TNTLCAVMGGDAIFEELQEHLGVGNGETTDDGKVTLEHIECNAACDYAPVVMVNWEFFD
                     NQTPASAKRLVDDLRAGRAVTPTRGAPLCTFKETARILAGFPDEREGAVEAGGSAGPAS
                     LVGLKLAKGESAPARVVHPRGAASAGAPPHEPSPAEHLSSHDAPQDTSASDPAHPAGPT
                     AEEGE"
     gene            complement(5118..6452)
                     /gene="sle_30670"
     CDS             complement(5118..6452)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VVP7"
                     /db_xref="InterPro:IPR001135"
                     /db_xref="InterPro:IPR014029"
                     /db_xref="InterPro:IPR022885"
                     /db_xref="InterPro:IPR029014"
                     /db_xref="InterPro:IPR038290"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VVP7"
                     /gene="sle_30670"
                     /product="NADH-quinone oxidoreductase subunit D 1"
                     /protein_id="CQR62528.1"
                     /transl_table=11
                     /translation="MSTHTPPSSASARETTEGTVYTVTGGDWDEVVQTAARADDERLIV
                     NMGPQHPSTHGVLRLILEIDGETVTEARCGIGYLHTGIEKNLEYRTWTQGTTFVTRMDY
                     LTPFFNETAYCLGVEKLLGIEDEVPDRASIIRVLLMELNRMSSHLVCIATGGMELGATT
                     IMIYGFRDRELILDIYELITGLRMNHAYIRPGGLAQDLPPGAVDRIREFVKQMKKNLPE
                     YDKLATGNPIFKARMQDIGYLDLAGCMALGATGPILRSTGLPHDLRKAQPYCGYETYDF
                     EVPTADTCDAYGRFLIRLEEMRQSLRIIEQCLDRLQPGPVMVADKKIAWPAQLALGPDG
                     LGNSLDHIKKIMGTSMEALIHHFKLVTEGFRVPPGQAYAAVESPKGELGAHVVSDGGTR
                     PYRVHFRDPSFTNLQAMAAMCEGGQVADVIVAVASIDPVMGGVDR"
     gene            complement(6449..7195)
                     /gene="sle_30680"
     CDS             complement(6449..7195)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VQ87"
                     /db_xref="InterPro:IPR001268"
                     /db_xref="InterPro:IPR010218"
                     /db_xref="InterPro:IPR037232"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VQ87"
                     /gene="sle_30680"
                     /product="NADH-quinone oxidoreductase subunit C"
                     /protein_id="CQR62529.1"
                     /transl_table=11
                     /translation="MSDAHQDADGVNPEKALSADNLPGQRGQGGEEIRVQRGMFGANNG
                     GDTSGYGGLVRSVRLPGPASRPYGGWFDEVADELEGALEEQGLLPGNAIEKTVVDRGEL
                     TFHIEREHLVRVARTLRDDPALRFELCTGVSGVHYPNDKGRELHAVYHLRSITHNRVIR
                     LEVSCPDGDPHIPSLFSVYPTNDWHERETYDFFGIVFDGHPALTRIMMPDDWQGHPQRK
                     DYPLGGIPVEYKGAQIPAPDQRRSYS"
     gene            complement(7192..7746)
                     /gene="sle_30690"
     CDS             complement(7192..7746)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VRX6"
                     /db_xref="InterPro:IPR006137"
                     /db_xref="InterPro:IPR006138"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VRX6"
                     /gene="sle_30690"
                     /product="NADH-quinone oxidoreductase subunit B 1"
                     /protein_id="CQR62530.1"
                     /transl_table=11
                     /translation="MGLEEKLPSGFLLTTVEQAAGWVRKSSVFPATFGLACCAIEMMTT
                     GAGRYDLARFGMEVFRGSPRQADLMIVAGRVSQKMAPVLRQVYDQMPNPKWVISMGVCA
                     SSGGMFNNYAIVQGVDHIVPVDIYLPGCPPRPEMLMDAILKLHHKIQNSKLGVNAEEAA
                     REAEEAALKALPTIEMKGLLR"
     gene            complement(7760..8119)
                     /gene="sle_30700"
     CDS             complement(7760..8119)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W0N7"
                     /db_xref="InterPro:IPR000440"
                     /db_xref="InterPro:IPR023043"
                     /db_xref="InterPro:IPR038430"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W0N7"
                     /gene="sle_30700"
                     /product="NADH-quinone oxidoreductase subunit A"
                     /protein_id="CQR62531.1"
                     /transl_table=11
                     /translation="MNAYAPILVLGALGAGFAIFSVVMATLIGPKRYNRAKLEAYECGI
                     EPTPTPAGGGRFPIKYYLTAMLFIIFDIEIVFLYPWAVSFDALGIFGLVEMLLFVLTVF
                     VAYAYVWRRGGLEWD"
     gene            8867..9739
                     /gene="sle_30710"
     CDS             8867..9739
                     /codon_start=1
                     /db_xref="InterPro:IPR000064"
                     /db_xref="InterPro:IPR038765"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VYD2"
                     /gene="sle_30710"
                     /product="Uncharacterized protein cgR_2070"
                     /protein_id="CQR62532.1"
                     /transl_table=11
                     /translation="MSHTAHIRSHRKPRRSASTIAMRAGVAGGVLSTLAVAGASGSANA
                     AEPVTQTLELPTLTADLAAQIAQSADATQQAAANYELQAERDAAAAQAAKEAKADLAEA
                     KKKAAEKKRKAEEAARKAAAERASRDAERAALSASVEISSESGSNSGSGSGSASASVGA
                     SAGVSTSTASGSAAAVVSFVQAQVGDAYVSGGTGPNSWDCSGLVQAAFRQVGIDLPRVS
                     QAQSTAGTQVSLSNLQPGDILYWGGAGSAYHVGVYVGDGMFVGAQNPSTGVALKSLSYD
                     PPSGAVRVL"
     gene            complement(10001..11284)
                     /gene="sle_30720"
     CDS             complement(10001..11284)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VVQ2"
                     /db_xref="InterPro:IPR002938"
                     /db_xref="InterPro:IPR011777"
                     /db_xref="InterPro:IPR036188"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VVQ2"
                     /gene="sle_30720"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     halogenated: Trp_halogenase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1161:oxidoreductase (Score: 221.2; E-value: 3.6e-67)"
                     /gene_kind="biosynthetic"
                     /product="Digeranylgeranylglycerophospholipid reductase"
                     /protein_id="CQR62533.1"
                     /sec_met_domain="Trp_halogenase (E-value: 1.8e-07,
                     bitscore: 29.0, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 2e-09, bitscore: 36.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEPLSDNTADVIVVGAGPAGSTTAYHLARAGLDVLLLEKSEFPR
                     EKVCGDGLTPRAVKQLVAMGIDISEEAGWLRNKGLRIVGGGVRLQLDWPELASFPDYGV
                     VRKRDDFDEQLARQAQKAGARLHERCNVGAPIVDDRTGRITGVRAKLGEDKREVTFHAP
                     LVVAADGNSTRLSLAMGLHRREDRPMGVAVRTYFTSPRHDDNYLESWLELWDRRGPQDR
                     LLPGYGWIFGMGDGTSNVGLGVLNTSDSFKELDWREVLKTWCASMPEDWGYTPENMTGP
                     IRGAALPMAFNRQPHYTRGLLLVGDAGGLVNPFNGEGIAYAMESGQIAADVIVQAHARS
                     TPAGREAALQRYPRVLKDTYGGYYTLGRAFVKLIGNPKVMQIAAQRGLTHPLLMKFTLK
                     LLANLTDPSGGDAMDRIINGLAKVAPKA"
     gene            11334..11885
                     /gene="sle_30730"
     CDS             11334..11885
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VQ89"
                     /db_xref="InterPro:IPR000182"
                     /db_xref="InterPro:IPR016181"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VQ89"
                     /gene="sle_30730"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111:GCN5-related N-acetyltransferase (Score: 93.4;
                     E-value: 2.5e-28)"
                     /gene_kind="biosynthetic-additional"
                     /product="Acetyltransferase"
                     /protein_id="CQR62534.1"
                     /transl_table=11
                     /translation="MGSLFSVTDHRLKGCPVNRALPVVRLRVPTHEDAVAWHRVFDHPD
                     VMEFHGGRSAELSVYEELTARQRRHDAERGFCLWTVLDEAGDVIGFTGAQPWPWEWGPT
                     GEIEIGWRLGRTHWGKGYVTAAARETLRRVRAAGVPGVVAMVDARNARSIAVTRRLGMN
                     LAEVYTTPSRREGHCYRLAL"
     gene            complement(11924..12619)
                     /gene="sle_30740"
     CDS             complement(11924..12619)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VRX8"
                     /db_xref="InterPro:IPR004033"
                     /db_xref="InterPro:IPR023576"
                     /db_xref="InterPro:IPR029063"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VRX8"
                     /gene="sle_30740"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 90.7; E-value:
                     1.8e-27)"
                     /gene_kind="biosynthetic-additional"
                     /product="Demethylmenaquinone methyltransferase"
                     /protein_id="CQR62535.1"
                     /transl_table=11
                     /translation="MTRASLDKQPHEVASMFDDVAERYDLTNDVLSLGHARLWRKEVAR
                     AVDARPAQKVLDLAAGTATSSLPFARTGAYVVPCDFSLGMLRVGKQRHSWLPFTAGDAT
                     RLPFKDDTFDAVTISFGLRNVHDTDAALRELHRVTRPGGRVVICEFSHPTWAPFRTVYT
                     EYLMRALPPVARAVSSNPDAYVYLAESIRAWPDQPALAARLGGAGWTKVAWRNLTGGVV
                     ALHRGFKAG"
     gene            complement(12650..13765)
                     /gene="sle_30750"
     CDS             complement(12650..13765)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W0P0"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W0P0"
                     /gene="sle_30750"
                     /product="Integral Membrane Protein"
                     /protein_id="CQR62536.1"
                     /transl_table=11
                     /translation="MGRHRKAAAPPAPAAPARAPHSPGPPDTAGRDRYFDALRAAALVR
                     VVTYHTFGWAWAGLVFPSMGIMFALAGTLMAKSLRRPAPGVIRRRLRRLLPPFWFWGAF
                     VVAAMLVHGWRPGGEIVHWIVPLGDPPGEAWAEQAWEIAWYLRTYLWFVLLSPLLLRLF
                     RRAPVPVLLGSLAPVVVFTFAWQPPENRLGGALTDLATYLFCWLLGFAHHDGVLRRARP
                     AAAVALSAAALACGLWYALAHQAEYGTYDLDENPLAQALWSAGFVTLLLYAKARRGTDL
                     AGLARVRWLDRLVTVLNARAVTVYLWHEIALILAVPLTDLLWRVPACAAYLPLGSQWFL
                     FGVCWLLLAALVPLCGWVEDLAARRKPRLLP"
     gene            complement(13765..16011)
                     /gene="sle_30760"
     CDS             complement(13765..16011)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VYD6"
                     /db_xref="InterPro:IPR002509"
                     /db_xref="InterPro:IPR011330"
                     /db_xref="InterPro:IPR029044"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VYD6"
                     /gene="sle_30760"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 112.1; E-value: 6e-34)"
                     /gene_kind="biosynthetic-additional"
                     /product="Poly-beta-1,6-N-acetyl-D-glucosamine synthase"
                     /protein_id="CQR62537.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.8e-35,
                     bitscore: 120.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTTPSRGRRRAPSRIERAAGKAAALQRPRVLLALLLLLALTSV
                     LLLDGYLRAEVGDDQRVRAGAGADDVPEDVLEGGPILTFPGGRATTVSVPDKTIVLTFD
                     DGPDPTWTPQVLKILEKHDVPGTFFVVGSMVARHPDIVRDMVEQGDEVGVHTFTHVDLS
                     YQSESRVTRELEQTQLALAGAAGITTTLFRAPYSSQTDAIDDYSWPVYQQLGEDGYTSV
                     FIDTDSDDWKEPGVSKIVQWATPEDGEGASVLFHDAGGDRSQTIAALPKYIEKMKAKGY
                     TFTTVSGAMEQQQQEAAGAAQGGTPPGAAAAGTGRGLQAAHHRATGTTLWEGRALVAAV
                     AVAEWTVPALSAGLVVVGVAVLGRFGLMLVLARRHHRRRNRRRFGWGPPVTRPVSVIVP
                     AYNEKECIANTLRSLARSTHPIEIIVVDDGSTDGTAEIAESLGLPDVRVVRQANAGKPA
                     ALNNGVRHARHDIVVMMDGDTVFEPETVRQLVQPFADPSVGAVAGNAKVGNRRTLIGAW
                     QHIEYVMGFNLDRRMYDLLRCMPTIPGAIGAFRREAVLQAGGMSEDTLAEDTDITIALH
                     RAGWRVVYQEHARAWTEAPGSLKQLWSQRYRWSYGTMQALWKHRGALTDRGPSGRFGRV
                     GLPLVVLFQILTPLFAPLIDVFTAYSMIFIDFRAALLAWLAVLAVQMLCAAYAFRLDGE
                     KYRYLLMMPLQQLAYRQMMYLVLIHSCVTALTGGRLRWQKLKRTGEVGTPAGTA"
     gene            complement(16031..16468)
                     /gene="sle_30770"
     CDS             complement(16031..16468)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VVQ6"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VVQ6"
                     /gene="sle_30770"
                     /product="Hypothetical Protein sle_30770"
                     /protein_id="CQR62538.1"
                     /transl_table=11
                     /translation="MHSEPAFESRAAVRGRRRKRGNGSAEGPVFVDTSGRRARLLRRLG
                     LLLGVVCLGYATVLGLAFMGIGTSVSPSSLLPFGGGRDDGRAPGAETRPGNGAPTGAPP
                     AGAQPPGQAPAPTGGASAAPSAPSTPSAPSATYAPSASATD"
     gene            16682..17758
                     /gene="sle_30780"
     CDS             16682..17758
                     /codon_start=1
                     /db_xref="InterPro:IPR017853"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VQ94"
                     /gene="sle_30780"
                     /product="Probable bifunctional chitinase/lysozyme"
                     /protein_id="CQR62539.1"
                     /transl_table=11
                     /translation="MRSTRTPRSTGGTRSARSARGTTHVRHPAAGLALLLVLATAGCAA
                     RDGAADAADAAPSASPSASAAPATGYAPYVSATTASDLDTAGSPTTYNLAFVVSSGSGC
                     VPRWGGTQAVDDPAVAARVAELKESGATVRVSFGGASGKELAATCDSAAELAEAYGAAL
                     DAAGSTRADFDIEGDELTDSASVALRSQAIALLQRERSGLEVSFTLPVMPSGLDADSLA
                     LLESANDHGVQVSTVNLMTMNYGESWTGDMGDYAVTSAEAAHTQLQRVFGLSDAAAWKG
                     MALTSMIGVNDVAGETFTLSDAAQVRAFATGKGIAWVSAWASFRDRRCGDDSAGEDAST
                     ECSGVEQEDGAFAQAFSG"
     protocluster    17091..27291
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[22090:22291]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      22091..22291
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
     cand_cluster    17091..27291
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="2"
                     /tool="antismash"
     gene            complement(17790..18395)
                     /gene="sle_30790"
     CDS             complement(17790..18395)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VRY5"
                     /db_xref="InterPro:IPR011059"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VRY5"
                     /gene="sle_30790"
                     /product="Conserved Hypothetical Protein"
                     /protein_id="CQR62540.1"
                     /transl_table=11
                     /translation="MLTIHADSRGRALAVEGAWIAEAGPLEEVAAARPGARLRRWPGIL
                     TPGLVNPYGDELLEGAYHPDPREADELGTEPLTGRALAALAPDEARWGASARRGLQRML
                     SHGTVAVACGELRIRAVRDAVHRSGLAVVGRIGRPGGVPSLDPYACGAPVTFAPPRERG
                     SAARFAVFDVPDEAALAERGAAACVATVVAGRLVYRRR"
     gene            complement(18404..19600)
                     /gene="sle_30800"
     CDS             complement(18404..19600)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W0P3"
                     /db_xref="InterPro:IPR006638"
                     /db_xref="InterPro:IPR007197"
                     /db_xref="InterPro:IPR013785"
                     /db_xref="InterPro:IPR020050"
                     /db_xref="InterPro:IPR022431"
                     /db_xref="InterPro:IPR034405"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W0P3"
                     /gene="sle_30800"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /product="FO synthase subunit 2 2"
                     /protein_id="CQR62541.1"
                     /sec_met_domain="PF04055 (E-value: 1.5e-17, bitscore: 63.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEKADLQPILDRAAAGGRITPDEALALYRDAPLHALGAAADAVR
                     RRRYAGTEHIATYIIERNINYTNVCVTACKFCAFYAPPKSDKGWTRDLDDILRRCAETV
                     ELGGTQIMFQGGHHPDFGVEYYEKHFAAIKKEFPQLVIHSLGASEVEHMARISGVSVEE
                     AITRIRDAGLDSFAGAGAELLPERPRKAIAPLKESGERWLEIMEIAHRLGVESTSTMLM
                     GTGETNAERIEHLRMIRDVQDRTGGFRAFIPYTYQPENNHLKGRTQATIFEYLRMIAIA
                     RLFLDNVAHIQGSWLTTGKEVGQLSLHYGADDLGSIMLEENVVSSAGARHRSNRLEIID
                     LIRKAGRVPAQRSTTYEHLVVHDDPANDPVDDRVVSHISSTAIEGGTAHPELKLLASN"
     gene            complement(19671..20516)
                     /gene="sle_30810"
     CDS             complement(19671..20516)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VYD9"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VYD9"
                     /gene="sle_30810"
                     /product="Integral Membrane Protein"
                     /protein_id="CQR62542.1"
                     /transl_table=11
                     /translation="MQTSNDMGTGRHRRPAEAFTGHLMPPDWNWDPAEELAFMLRDALE
                     EQPPGDPYPEASVTAPAPGTPLGNLQEITAELPPLKDSPKGHRKVREPRRINGRRAVSH
                     FLAASVAAIACAVSVFGGVFSYESLLRSAASRTGSDMVSWWPFLVYGPWMVASLSVLRA
                     ALYQRRAVHSWSVVLFFSCMAMLLCVAQLPVTLVDAATATLPGLASLACFQQLVRQITL
                     TRPPRRVIPRHRLRPMPVPDPGEPARTTARESASLPKQRTSAMVRGGEERVRRTGLGGA
                     "
     gene            complement(20578..20793)
                     /gene="sle_30820"
     CDS             complement(20578..20793)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VVR0"
                     /gene="sle_30820"
                     /product="Hypothetical Protein sle_30820"
                     /protein_id="CQR62543.1"
                     /transl_table=11
                     /translation="MLGPYTYFPAPAHSVRTAGRTPTRDGLPVTLQVTEPIPRHFPTVT
                     TELESESDPARRWGTPQDASALSSAE"
     gene            complement(20995..21804)
                     /gene="sle_30830"
     CDS             complement(20995..21804)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VQ97"
                     /db_xref="InterPro:IPR000045"
                     /db_xref="InterPro:IPR014032"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VQ97"
                     /gene="sle_30830"
                     /product="Type 4 prepilin-like proteins leader
                     peptide-processing enzyme"
                     /protein_id="CQR62544.1"
                     /transl_table=11
                     /translation="MSVLPAVVAAALWGAATGALLPRAAYRFSVPPDESWRTECPAGHP
                     VRGWLGPARCGPCAAAGAPPQAPPGAPPGSGTGPSYGPGAPAFATATLVVCAALAAATG
                     PRPELAVWLLLAPAGVLLAAVDLRVRRLPDLLTLPLAGAALALLGLAARVPGHAGGWTT
                     ALLGSLALGGGYFVLFLLNPEGMGFGDVKLALGAGAVLGWYGWATLALGAVAGLLLGAL
                     YGWALVAVRRGGRGTAVPYGPFLIAGALLGVLAGACRHGPFPFLVPA"
     gene            complement(22091..22291)
                     /gene="sle_30840"
     CDS             complement(22091..22291)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VRY8"
                     /gene="sle_30840"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: strepbact"
                     /gene_kind="biosynthetic"
                     /product="Hypothetical Protein sle_30840"
                     /protein_id="CQR62545.1"
                     /sec_met_domain="strepbact (E-value: 1.3e-14, bitscore:
                     53.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLTPQVETAEMSEADLDNIAGGLAAGASAGVFAEVDAVAAVCAG
                     VGVGVNVEGVSADVVAHVAAL"
     gene            complement(22515..22721)
                     /gene="sle_30850"
     CDS             complement(22515..22721)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W0P6"
                     /gene="sle_30850"
                     /product="Hypothetical Protein sle_30850"
                     /protein_id="CQR62546.1"
                     /transl_table=11
                     /translation="MVARPGGNPPARLAAVPENPTDLHTVHRCLISELNASQLRDSLPD
                     LPRPVRAGIAGHPPAGSAGPRTV"
     misc_feature    complement(22605..22607)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    22771..22786
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            complement(22783..23631)
                     /gene="sle_30860"
     CDS             complement(22783..23631)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VYE2"
                     /db_xref="InterPro:IPR003773"
                     /db_xref="InterPro:IPR030868"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VYE2"
                     /gene="sle_30860"
                     /product="Hypothetical"
                     /protein_id="CQR62547.1"
                     /transl_table=11
                     /translation="MDNSRTRPRVGHIQFLNCLPLYWGLARTGTLLDFELTKDTPEKLS
                     EQLVRGDLDIGPITLVEFLKHADRLVAFPDIAVGCDGPVMSCVIVSQVPLERLDGARVA
                     LGSTSRTSVRLARLLLEERIGVRPDYYTCPPDLGLMMREAEAAVLIGDAALRANMLDGP
                     RYGLDVHDLGALWKEWTGLPFVFAVWAARRDYLEREPVITRKVHEAFLASRNLSLQEVD
                     KVAEQAARWEAFDEGTLARYFKTLDFRFGAPQLEAVAEFARRVGPTTGFPADVKVELLQ
                     P"
     gene            23933..24136
                     /gene="sle_30870"
     CDS             23933..24136
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VVR5"
                     /db_xref="InterPro:IPR002059"
                     /db_xref="InterPro:IPR011129"
                     /db_xref="InterPro:IPR012156"
                     /db_xref="InterPro:IPR012340"
                     /db_xref="InterPro:IPR019844"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VVR5"
                     /gene="sle_30870"
                     /gene_functions="regulatory (smcogs) SMCOG1255:cold-shock
                     DNA-binding domain protein (Score: 103.5; E-value:
                     8.1e-32)"
                     /gene_kind="regulatory"
                     /product="Cold shock-like protein 7.0"
                     /protein_id="CQR62548.1"
                     /transl_table=11
                     /translation="MATGTVKWFNAEKGFGFIAQEGGGPDVFVHYSAINASGFRSLEEN
                     QQVSFDVTQGPKGPQAENVTPV"
     gene            complement(24273..24848)
                     /gene="sle_30880"
     CDS             complement(24273..24848)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VQA1"
                     /db_xref="InterPro:IPR001387"
                     /db_xref="InterPro:IPR010982"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VQA1"
                     /gene="sle_30880"
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 97.6; E-value: 1.8e-29)"
                     /gene_kind="other"
                     /product="Uncharacterized HTH-type transcriptional
                     regulator ydcN"
                     /protein_id="CQR62549.1"
                     /transl_table=11
                     /translation="MPDDAAALPSRLPLDWIAASLRRERTRAGLSLSELAKRAGIAKST
                     LSQLEAAGGNPSMETIWALAVALGVPFSALVEPPVSSVQVIRAGEGPQVTSERASFVGT
                     LLAACPPGARRDIYRMRAEPGPARESDPHIPGTVEHLVVSTGRMKAGPRGESVELGPGD
                     YMAYRGDVPHTYQALEPGTTFVLIMQHV"
     gene            25040..25651
                     /gene="sle_30890"
     CDS             25040..25651
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VRZ4"
                     /db_xref="InterPro:IPR011606"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VRZ4"
                     /gene="sle_30890"
                     /product="AzlC Family Protein"
                     /protein_id="CQR62550.1"
                     /transl_table=11
                     /translation="MSFGAISVAGGLPVWVPVVMSLVVYAGSAQFSAVGVLLAGGGPLA
                     AAATGLLLNTRLAAFSLAVAGILGRGWPSRLLGAHLVTDETVAFALAQQDPGRRRAAFW
                     LSGCALFALWNVGVLAGALAGTALGDTAVYGLDAAFPAVLAALVLPALREDASLRRAAL
                     PGAALALAVTPVVPAGVPVLLALAGLLLHRGGARPEGRPA"
     gene            25648..25962
                     /gene="sle_30900"
     CDS             25648..25962
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W0Q0"
                     /db_xref="InterPro:IPR008407"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W0Q0"
                     /gene="sle_30900"
                     /product="Hypothetical Protein sle_30900"
                     /protein_id="CQR62551.1"
                     /transl_table=11
                     /translation="MNATVAVILALAAGTYVLRLAGPVLHGRVTLPARVRELLSAGAVV
                     LLVALLATGALTEGGGFAGWARPAGVLAGAVLAWRRAPFAVVVLGAAGVAALLRAVGVE
                     "
     gene            26060..26695
                     /gene="sle_30910"
     CDS             26060..26695
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VYE4"
                     /db_xref="InterPro:IPR029063"
                     /db_xref="InterPro:IPR041698"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VYE4"
                     /gene="sle_30910"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 96.5; E-value: 3e-29)"
                     /gene_kind="biosynthetic-additional"
                     /product="Methyltransferase"
                     /protein_id="CQR62552.1"
                     /transl_table=11
                     /translation="MTDTDHLTATRTFYDAIAEDYAEHFRGQVAGAPQDLEVLAAFARL
                     VGPGAEVADLGCGPGRVTAHLAGLGLRVFGLDLSASMLAVARRENPHLRFEQGSMLELD
                     RPDGSLAGVVSWYSSIHTPAEELPDLFAEFRRVLAPGGHLLLAFQAGDAPLRLDRPFDR
                     PVGLDFQRRRPERMAGLLQDAGFTLHSRTLREPGETESAPQAFLIARR"
     misc_feature    26981..26995
                     /note="TFBS match to ZuR, Zinc-responsive repressor,
                     confidence: weak, score: 20.21"
                     /tool="antismash"
ORIGIN
        1 gatgtacagc atcgcgatcg gcaggtcggt gagctgcatc gtggtgcgct ggccgaagat
       61 ggagatctcg ttgccggacg ggccgaaggg gatcaccgcg atcgccatga aggccgggat
      121 ggccgcgacg atcggcgcga ggacgtacac cgccttgtcc gcgcgcttga cgacgacgtc
      181 ctccttgagc atcagcttga tgccgtcggc gagcgactgg agcaagcccc aggggccgtg
      241 ccggttgggg ccgatgcgca actgcatcca ggcgacgacc ttgcgctcca tgacgatggc
      301 gatcagcacg gtcaccatca ggaaggcgaa gcagaacacc gccttgacgg cgatcagcca
      361 ccacgggtcg cggccgaaca tcgagaggtc ttcagcggcg aggtacgggc tcatgcctcc
      421 acctcctggg gagcctcggc ggcggatttc gccgggccga tgcggacgag ggagccgggc
      481 agcgccccgg tgtcggcggc gacgccgccg ccggtggagt tcagcgggag ccacaccacg
      541 cggtcgggca tctcggtgac ccgcagcggg agggcgacgg agccggcggg gccggtcacc
      601 gcgaggacgt cgccgtcctc gacccccacc tcggcggccg tggcgggcga cacgcgcgcg
      661 tgtgcggcgt gacgggtccc ggcgagcgcc tcgtcgccct gctggagcag gccctggtcg
      721 agcaggagcc ggtgcccggc gagcacggcc tccccggcgg ccggccgagg cagcggcccc
      781 gccgtctcca ggggttcggt ggcccgcggg ccgtcccaga cgccgagccg gtccagttcc
      841 gcgcgcacgg tccgcaggtc gggcaggccc aggtggacgt ccatggcgtc ggcgagcatc
      901 tgcagcaccc gcgcgtcggt gggcggcagg cggtgcgcca tctggtcggg cttgagcgcg
      961 gcctcgaaga ggcggacccg gccctcccag ttgaggaagg tcccggcctt ctccgcgacc
     1021 gccgccacgg gcagcaccac gtcggcgagc gcgctgacct cgctgggccg cagctccagc
     1081 gagaccagga aaccggcctc ggcgagcgcg gcacgcgcgc gtgccgggtc cggcaggtcg
     1141 gccacctcca cgcccgccac cagcagggcc tggagttcgc ccgtggcggc ggcctcgatg
     1201 atctggccgg tgtcgcggcc gtagcggtgc ggcagtccgg ccacgcccca gacggcggcg
     1261 acctcctccc gcgcgcgcgg gtcggtggcc gggcgcccgc ccggcaacag ggacggcagc
     1321 gctcccgcct cgaccgcgcc gcgctcgccc gcccggcgcg ggatccacgc caggtgggcg
     1381 ccggtcgcgg cggcggcccg cacggccgcg gtgagaccgc cggcgacgcc cgccaggcgc
     1441 tcaccgacga cgatcacggc gccctcggcg cgcagcgcct cggcggcccg gctgccgtcc
     1501 tcgtccaggc cgacaccggc ggcgagcgcg tccagccact cggtctcggt gccgggcgcg
     1561 gccggcagca gcgtgccccc ggccttctcc agaccgcggg tggcgtgggt ggccagcgcg
     1621 aacacctgct gtccgtgccc ccgccacgcc ttgcgcagcc gcaggaagac gccgggcgcc
     1681 tcctcctcgg cctcgaagcc ggccagcagc acggcgggcg ccttctccag cgcggtgtag
     1741 gtgacaccgg cgccgtcgag gtcgcgtccg cgtccggcga cccgggcggc caggaagtcg
     1801 gcctcctcgc cgctgtgcac acgggcgcgg aagtcgatgt cgttggtgtc gagcgccacg
     1861 cgcgcgaact tgctgtacgc gtaggcgtcc tccacggtga gccgcccgcc ggtcaggacg
     1921 ccggtgcggc cccgggaggc gagcagcccc tgtgcggcga tctgcagcgc gtccggccag
     1981 gaggccggtt ccagctcgcc ctccgcgttg cgcaccagcg gcgtccggag acggtcccgc
     2041 tgttgcgcgt accggaacgc gaagcgcccc ttgtcgcaga tccactcctc gttgacctcg
     2101 gggtcgtggg cggccaggcg ccgcatgacc ttgccgcgcc ggtggtcggt gcgggtggcg
     2161 cagccgccgg agcagtgctc gcacaccgac ggcgaggaga ccaggtcgaa gggacgggag
     2221 cggaaccggt acgccgccga ggtcagcgcg ccgaccgggc agatctggat ggtgttgccg
     2281 gagaagtacg actcgaacgg gtcgccctcg ccggtgccga cctgctggag cgcgccccgc
     2341 tcgaccagct cgatcatcgg gtcgccggcg atctggttgg agaagcgggt gcagcgcgcg
     2401 cacagcacgc accgctcccg gtcgagcagc acctgcgtgg agatcggcac gggcttctcg
     2461 tacgtgcgct tcctgccctc gaagcgggac tcggcgttgc cgtgcgacat cgcctggttc
     2521 tgcagcgggc actcgccgcc cttgtcgcac accgggcagt ccagcgggtg gttgatgagc
     2581 agcagctcca tcacaccctt ttgggccttc tccgcgaccg gcgaggtgag gtgggtcttg
     2641 accaccatcc cgtcggtgca ggtgatggtg caggacgcca tgggcttgcg ctggccctcg
     2701 acctcgacga tgcactggcg gcaggcgccg gccggatcga ggagcgggtg gtcgcagaac
     2761 cgggggatct cgatgccgag ctgctcggcg gcccggatga ccagggtgcc cttgggcacg
     2821 ctgatctcga tgccgtcgat cgtcagggtc acgaggtctt ccggcgggcg tgccgcctcg
     2881 ccccccgagg agggagcgct ggtggtcaca gtcatgcgtt cacctccgta cggtgatcgg
     2941 cccaggccgt ggacttggcg gggtcgaacg ggcagccgcg gcccgtgatg tgctcctcgt
     3001 actcctcgcg gaagtacttg agggaggaga agatcggcga ggcggcgccg tcgccgaggg
     3061 cgcagaagga cttgccgttg atgttgtcgg cgatgtcgtt cagcttgtcg aggtcggaca
     3121 tgacgccctt gccggcctcg atgtcgcgca gcaactgcac cagccagtac gtgccctcgc
     3181 ggcagggcgt gcacttgccg caggactcgt gggcgtagaa ctcggtccag cgggtgacgg
     3241 cccggacgac gcaggtcgtc tcgtcgaagc actggagggc cttcgtgccg agcatggagc
     3301 ccgcggcacc cactgcctcg tagtcgagcg ggacgtcgag gtgctcgtcg gtgaacatcg
     3361 gggtcgagga gccccccggc gtccagaact tcaggcggtg cccggggcgc atgccgccgc
     3421 tcatctccag gagctggcgc agcgtgatcc cgagcggcgc ctcgtactgg ccggggctcg
     3481 cgacgtggcc ggagagggag tagagcgtga agcccgggga cttctcgctc cccatcgagc
     3541 ggaaccactc cttgccccgg tgcatgatcg cgggaaccga ggcgatcgac tcgacgttgt
     3601 tcaccacggt ggggcacgcg tacaggcccg cgacggcggg gaagggggga cgcagccgcg
     3661 gctgtccgcg ccggccctcg agcgagtcca gcagcgcggt ctcctcaccg cagatgtacg
     3721 cgcccgcgcc cgcgtgcacg gtgagttcga ggtcgagtcc gctgccgagg atgtccgtgc
     3781 cgaggtagcc cgccgcgtac gcctcgcgca cggcctcgtg cagccgccgc aggacgggga
     3841 cgacctctcc ccgcagatag atgaaggcgt gcgacgaccg gatggcgtag cacgcgatca
     3901 cgatgccctc gatgaggctg tgcgggttgg cgaagaggag cgggatgtcc ttgcaggtgc
     3961 ccggctccga ttcgtcggcg ttgaccacca ggtagtgggg cttgccgtcc ccttgcggga
     4021 tgaactgcca cttcatgccc gtggggaagc cggcgccgcc gcgtccgcgc agaccggagt
     4081 ccttcacgta ggcgatcacg tcgtccggtg acatggccag cgccttgcgg agcccctcgt
     4141 acccctcgtg ccgccggtag acgtcgagcg tccaggacct ctcctcgtcc cagaaggccg
     4201 acagcacggg tgcgagcagc ttctccgggc tggtgtcctt gatctcggtc gccacggtca
     4261 tcactccccc tcctcggcgg tgggcccggc ggggtgcgcg gggtcggagg ccgaggtgtc
     4321 ctggggcgcg tcgtgcgagc tcaggtgctc ggccggggac ggctcgtgcg gcggcgcgcc
     4381 ggcggaggcc gcgccgcgcg ggtgcaccac gcgcgcggga gcgctctcgc ccttggccag
     4441 cttcaggccg acgagggagg cgggcccggc gctgccgccc gcctcgacgg cgccctcccg
     4501 ctcgtcgggg aagccggcca ggatccgcgc cgtctccttg aaggtgcaca gcggcgctcc
     4561 gcgcgtcggg gtgaccgcgc gtcccgcgcg caggtcgtcg acgaggcgtt ttgcgctggc
     4621 gggcgtctgg ttgtcgaaga actcccagtt gaccatcacg accggcgcgt agtcgcaggc
     4681 cgcgttgcac tcgatgtgct ccagggtgac cttgccgtcg tcggtggtct cgccgttgcc
     4741 gacgcccagg tgctcctgga gctcttcgaa gatggcgtcg ccgcccatga cggcgcacag
     4801 ggtgttggtg cagacgccga cctggtagtc gccgctgggc cggcgccggt acatggtgta
     4861 gaaggtggcg accgcggtca cctcggccgt ggtcaggccg agcatgtccg cgcagaaccg
     4921 catgccggtg cgggtgacgt ggccctcctc cgactgcacc aggtgcagca gcggcagcag
     4981 ggcggagcgg gagtccgggt agcgggcgat gacctcgcgc gcgtcggcct ccagccgggc
     5041 gcggacgtcg tccgggtatt cgggcgcggg cagttcgggc atgcccaggc tgacgccccg
     5101 ctccgaggaa ctggtggtca ccggtcgacg cctcccatca cggggtcgat ggacgcgacg
     5161 gcgacgatga cgtcggcgac ctggccgccc tcgcacatcg ccgccatggc ctgaaggttg
     5221 gtgaaggacg ggtcgcggaa gtggacccgg taggggcggg tgccgccgtc ggagacgacg
     5281 tgcgccccga gctcgccctt gggcgattcg accgccgcgt acgcctgtcc cggcgggacg
     5341 cggaagccct cggtgaccag cttgaagtgg tggatcagag cctccatgga ggtgcccatg
     5401 atcttcttga tgtggtcgag ggagttgccg agcccgtccg gtcccagggc gagctgggca
     5461 ggccaggcga tcttcttgtc ggcgaccatg accgggccgg gctggagccg gtccaggcac
     5521 tgctcgatga tccgcaggga ctggcgcatc tcctccaggc ggatcaggaa gcggccgtag
     5581 gcgtcgcagg tgtcggcggt cggcacctcg aagtcgtacg tctcgtagcc gcagtacggc
     5641 tgcgccttgc gcaggtcgtg cggcagtccg gtggagcgca ggatcggccc ggtggcgccg
     5701 agggccatgc agccggccag gtccaggtag ccgatgtcct gcatgcgggc cttgaagatg
     5761 gggttcccgg tggcgagctt gtcgtactcc gggaggttct tcttcatctg cttcacgaac
     5821 tcgcggatcc ggtccaccgc gccgggcggc aggtcctggg cgagtccgcc ggggcggatg
     5881 taggcgtggt tcatccgcag gccggtgatc agctcgtaga tgtcgaggat cagttcacgg
     5941 tcgcggaagc cgtagatcat gatcgtggtg gcgccgagct ccatgccgcc ggtggcgatg
     6001 cacaccaggt gcgacgacat ccggttcagc tccatcagca gcacccggat gatcgaggcc
     6061 cggtccggca cctcgtcctc gatgcccagc agcttctcga cgcccaggca gtacgccgtc
     6121 tcgttgaaga acggcgtcag gtagtccatg cgcgtcacga acgtggtgcc ctgggtccac
     6181 gtgcggtact cgaggttctt ctcgatgccg gtgtgcaggt agccgatgcc gcagcgggcc
     6241 tcggtgaccg tctcgccgtc gatctccagg atcaggcgga gcacgccgtg cgtggacggg
     6301 tgctgcgggc ccatgttgac gatcagccgc tcgtcgtcgg cgcgggccgc ggtctggacg
     6361 acctcgtccc agtcgccgcc ggtgaccgtg tagacggtgc cctcggtggt ctcgcgggcc
     6421 gaggccgagg agggaggagt gtgcgtgctc atgagtacga cctccgctgg tccggagccg
     6481 ggatctgggc gcccttgtac tcgacgggga tgccgccgag ggggtagtcc ttgcgctgcg
     6541 gatggccctg ccagtcgtcc ggcatcatga tccgcgtcag ggcggggtga ccgtcgaaga
     6601 cgatgccgaa gaagtcgtag gtctcgcgct cgtgccagtc gttggtcggg taaacggaga
     6661 acagcgacgg gatgtgcgga tcgccgtccg ggcagctcac ctccaggcgg atcacccggt
     6721 tgtgggtgat cgagcgcagg tggtagacgg cgtgcagctc gcgccccttg tcgttcgggt
     6781 agtggacgcc gctgacgccg gtgcacagct cgaagcgcag ggccgggtcg tcgcgcaggg
     6841 tgcgggcgac gcggaccagg tgctcgcgct cgatgtggaa ggtcagctcg ccgcggtcga
     6901 cgaccgtctt ctcgatggcg ttgccgggca gcaggccctg ctcctccagc gcgccctcca
     6961 gctcgtcggc gacctcgtcg aaccagccgc cgtacggcct gctcgccggc cccgggagtc
     7021 ggaccgagcg gaccaggccc ccgtagccgg aggtgtcgcc gccgttgttc gcgccgaaca
     7081 tgccgcgctg gacgcggatc tcctcgccgc cctggccgcg ctggccgggg aggttgtcgg
     7141 cggagagcgc cttctcgggg ttgacgccgt ctgcgtcctg gtgcgcgtcg ctcatcgcag
     7201 cagccccttc atctcgatcg tgggcagggc cttgagcgcc gcctcctccg cctcgcgggc
     7261 cgcctcctcg gcgttcacgc ccagcttgga gttctggatc ttgtggtgga gcttgaggat
     7321 ggcgtccatc agcatctcgg gccgcggcgg gcagccgggg aggtagatgt cgaccgggac
     7381 gatgtggtcg accccctgga cgatcgcgta gttgttgaac atgccgcccg aggaggcgca
     7441 cacgcccatg gagatcaccc acttggggtt cggcatctgg tcgtagacct gccgcagcac
     7501 cggcgccatc ttctggctga cccggcccgc gacgatcatc aggtccgcct ggcgcggcga
     7561 cccgcggaag acctccatgc cgaagcgcgc caggtcgtag cggccggcgc cggtggtcat
     7621 catctcgatg gcgcagcagg cgaggccgaa cgtggcgggg aagaccgacg acttccgcac
     7681 ccagcccgcg gcctgctcga cggtggtgag caggaatccg ctcggcagct tttcttcgag
     7741 tcccatgact aaaggcccct cagtcccatt ccaggccgcc gcgccgccat acgtacgcgt
     7801 acgcgacgaa gacggtgagc acgaagagca gcatctccac gagcccgaaa atccccaggg
     7861 cgtcgaagct gacggcccag gggtagagga agacgatctc gatatcgaag atgatgaaga
     7921 gcatcgccgt caggtagtac ttgatcggga agcgcccgcc gccggccggc gtgggggtcg
     7981 gctcgatacc gcactcgtag gcctcgagct tggcccggtt gtaccgcttc ggaccgatca
     8041 acgtggccat gaccacggag aagatcgcaa agcctgcccc gagggctccc agtacgagga
     8101 tgggcgcata cgcgttcacc gctcctcgct cctctcagtc ggcactgact ggtggcggtt
     8161 ctgcgtcggg ctcacagccg ccccggcagt cccacgagcc ccgctggtcc cccgacgaag
     8221 atcgcgaaca tgtgaagcag gtcacaagcc caactgcctc gcatcttatg cctgccgctc
     8281 tgtgatctgc gacacggggt tccccatgag ctttgtgatc tccaccacct gacgaaggat
     8341 catgaagtcg gatgagcagc gatcttcata caggaagcat ccgagcaatc acgatatgtg
     8401 acatatcagc ttgtccatgc tggtcaggcg gatcgtctca ctatcaagag agttcccgtg
     8461 catgcaaatt cgcgctggac ttgatctctt gatagggggc gcctgcacgc atttgcgggg
     8521 gcacaggaag ggcggcggcg cgtgcacgcg ttcacgaact ccgcccggtc cggggtgcgc
     8581 gcgtccgacg cggccgtggc ggtaatcgtt ccgtgacctc cgccacattc atgagagctc
     8641 catgaaagcg ggggttggcc atctgcccca accagtggta agtgaggggc aattcgggcg
     8701 tatcgacgaa agtccgtgat cacagggggg tcacgccgcg cccgcaatgt ccgttagggc
     8761 gtcaataaac gccgacacgc ccgggattcg gggggtcgga cgggcaactg tggcggacga
     8821 cacgtttctt gaaggtatga aggagcccct ggtaccgctt gtactcatgt cccacaccgc
     8881 tcacatacgc agccaccgga agccccgccg cagcgcgtcg accatcgcca tgcgggccgg
     8941 agttgccggt ggcgtcctca gcaccctggc agtggccggg gcgtccggtt cggccaacgc
     9001 ggccgagccg gtgacgcaga ccctcgagct gcccaccctg acggccgacc tggccgccca
     9061 gatcgcccag tccgcggacg ccacccagca ggccgccgcc aactacgagc tgcaggccga
     9121 gcgcgacgcg gccgccgccc aggccgccaa ggaggccaag gcggacctgg ccgaggccaa
     9181 gaagaaggcc gcggagaaga agcggaaggc cgaggaggcc gcccgcaagg ccgccgccga
     9241 gcgcgcctcg cgcgacgccg agcgggccgc gctcagcgcc tccgtggaga tctcctccga
     9301 gtccgggtcg aactccggct ccggctccgg ctccgcttcc gcgagcgtcg gtgcgagcgc
     9361 cggcgtgagc acctccaccg cgtccggctc ggccgccgcg gtggtctcct tcgtccaggc
     9421 gcaggtcggc gacgcctacg tctccggcgg caccggcccg aactcctggg actgctccgg
     9481 cctggtgcag gccgccttcc gccaggtcgg catcgacctg ccgcgtgtct cgcaggccca
     9541 gtcgaccgcg ggcacccagg tgtcgctgag caacctccag ccgggcgaca tcctgtactg
     9601 gggcggcgcg ggcagcgcct accacgtggg cgtgtacgtc ggcgacggca tgttcgtcgg
     9661 cgcccagaac ccgtccaccg gcgtcgccct caagtcgctg tcgtacgacc cgccgagcgg
     9721 cgcggtgcgc gtgctgtagg acgcgcgcac gtccctacgc cgtccctgtg ccgcggacac
     9781 gtccgtacgc cgcggacacg tccgtacgcg gccgagacac ccgtacgccg cggacacatg
     9841 cgtacgaagg gccgcacccg cttccagggg tgcggccctt cgcgctttcc ggtcggggcg
     9901 agccggccgc ggacctggcg gccggtcagg ccggggtccg ggccgccgcg cgggtccggc
     9961 cctggcctga ccggcggccg cggtggccgg cggggtccgg tcacgccttc ggcgccacct
    10021 tggccaggcc gttgatgatg cggtccatcg cgtcgccgcc gctcgggtcg gtcaggttgg
    10081 ccaggagctt gagcgtgaac ttcatcagca gcgggtgggt gaggccgcgc tgggccgcga
    10141 tctgcatgac cttcgggttg ccgatgagct tcacgaaggc gcggccgagc gtgtagtagc
    10201 cgccgtaggt gtccttcagg acgcgcgggt agcgctgcag ggccgcctcg cgcccggcgg
    10261 gcgtcgagcg cgcgtgggcc tggacgatga cgtcggcggc gatctggccg gactccatgg
    10321 cgtacgcgat gccctcgccg ttgaaggggt tcaccaggcc gccggcgtcg cccacgagga
    10381 gcaggccgcg ggtgtagtgg ggctggcggt tgaaggccat ggggagggcg gcgccgcgga
    10441 tcgggccggt catgttctcc ggggtgtagc cccagtcctc gggcatggag gcgcaccacg
    10501 tcttcaggac ctcgcgccag tccagctcct tgaaggagtc ggaggtgttg aggacgccga
    10561 ggccgacgtt ggaggtgccg tcgcccatgc cgaagatcca gccgtatccg ggcagcagcc
    10621 ggtcctgggg gccgcggcgg tcccacagct ccagccagga ctccaggtag ttgtcgtcgt
    10681 ggcgcgggga ggtgaagtag gtgcggaccg cgacgcccat cgggcggtcc tcgcggcggt
    10741 gcaggcccat cgccagggag agccgggtgg agttgccgtc ggcggcgacg accagcggcg
    10801 cgtggaaggt gacctcccgc ttgtcctcgc cgagcttggc gcgcacaccg gtgatgcggc
    10861 cggtgcggtc gtcgacgatc ggcgcgccga cgttgcagcg ctcgtggagg cgggcgcccg
    10921 ccttctgggc ctgccgggcg agctgctcgt cgaagtcgtc gcgcttgcgg acgactccgt
    10981 agtcggggaa ggaggcgagt tccggccagt cgagctggag gcggacgccg ccgccgacga
    11041 tgcgcaggcc cttgttgcgc agccagccgg cctcctcgga gatgtcgatg cccatggcca
    11101 cgagctgctt gacggcgcgc ggggtgagtc cgtcgccgca gaccttctcc cgcgggaact
    11161 ccgatttctc cagcagcagt acgtcgagcc ctgccctggc caggtggtac gcggtcgtgg
    11221 agccggctgg gcccgcgccc acgacgatca catcggcggt gttgtcggag aggggctcgg
    11281 tcacggcggg atctccccag aactcgaaat ctgcgtgccg accggcactg gacatgggca
    11341 gtctattcag cgtcaccgat caccggctga agggctgccc cgtgaaccga gctctccccg
    11401 tggtacggct ccgcgtcccc acccatgagg acgcggtcgc ctggcaccgg gtgttcgacc
    11461 acccggacgt catggagttc cacggcggca ggtccgccga actgtccgtc tacgaggagc
    11521 tgaccgcccg ccagcgccgg cacgacgccg agcgcggctt ctgcctgtgg accgtgctgg
    11581 acgaggccgg ggacgtcatc ggcttcacgg gagcccagcc ctggccgtgg gagtggggcc
    11641 cgacgggcga gatcgagatc ggctggcggc tggggcggac ccactggggc aagggctacg
    11701 tcacggcggc ggcccgggag acgctgcggc gggtgcgcgc cgcgggcgtg ccgggcgtgg
    11761 tggccatggt cgacgcccgc aacgcccgct ccatcgcggt cacccggcgg ctgggcatga
    11821 acctggcgga ggtctacacg acgccgtccc ggcgggaggg gcactgctac cggctcgccc
    11881 tgtgacgccg cgtgcccgag gggccggagg ccccacgggg tcctcagccc gccttgaacc
    11941 cccggtgcag cgccaccacg ccgccggtga ggttgcgcca cgccaccttc gtccagccgg
    12001 ccccgcccag gcgcgcggcg agcgcgggct ggtccggcca ggcgcggatg gactcggcga
    12061 ggtagacgta ggcgtccggg ttggaggaga ccgcgcgggc caccggcggc agcgcccgca
    12121 tcaggtactc ggtgtagacg gtgcggaacg gcgcccaggt ggggtgggag aactcgcaga
    12181 tgaccacgcg tccgccgggc cgcgtcaccc ggtgcagctc gcgcagcgcg gcgtcggtgt
    12241 cgtggacgtt gcgcagcccg aaggagatcg tcaccgcgtc gaaggtgtcg tccttgaagg
    12301 gcagccgggt ggcgtcgccg gcggtgaacg gcagccagga gtgccgctgc ttgccgaccc
    12361 gcagcatgcc gagggagaag tcgcagggca cgacgtaggc gccggtgcgg gcgaagggga
    12421 gcgacgaggt cgccgtgccg gcggccaggt ccagcacctt ctgcgccgga cgggcgtcga
    12481 cggcccgggc gacctccttg cgccacagcc gggcatggcc gagcgagagc acgtcgttgg
    12541 tcaggtcgta ccgttccgcc acgtcgtcga acatcgaggc gacttcgtgc ggctgcttgt
    12601 ccagggaggc gcgggtcacg ggcccattgt ggcagcaagg ggtgcggcat cacggcagca
    12661 gcctcggctt ccgccgcgcc gccaggtcct ccacccaccc gcacagcggc accagcgcgg
    12721 cgagcagcag ccagcagacg ccgaacagga accactggct gcccagcggc aggtacgccg
    12781 cgcaggcggg cacccgccag agcaggtcgg tcagcgggac ggccaggatc agcgcgatct
    12841 cgtgccacag gtagaccgtg acggcccgcg cgttgagcac ggtcaccagc cggtccagcc
    12901 accgcacccg ggcgagcccg gcgaggtccg tgccgcgccg ggccttggcg tacagcagca
    12961 gcgtcacgaa accggccgac cacagggcct gggcgagcgg gttctcgtcg aggtcgtagg
    13021 tgccgtactc ggcctggtgg gccagggcgt accagaggcc gcaggcgagc gcggccgccg
    13081 acagggccac ggccgcggcg ggccgtgcgc ggcgcagcac cccgtcgtgg tgggcgaagc
    13141 cgagcagcca gcagaacagg taggtcgcga ggtccgtcag cgcgccgccg aggcggttct
    13201 ccggcggctg ccaggcgaac gtgaacacca cgaccggggc gagggagccc agcagcaccg
    13261 gcacgggcgc ccgccggaac aggcgcagca gcagcgggga gagcaggacg aaccacagat
    13321 aggtccgcag gtaccaggcg atctcccacg cctgctcggc ccacgcctcg cccggcgggt
    13381 cgccgagcgg cacgatccag tggacgatct ccccgcccgg ccgccagccg tgcaccagca
    13441 tggcggcgac cacgaaggcg ccccagaacc agaacggcgg cagcaggcgc cggagcctgc
    13501 gccggatcac cccgggcgcg ggccgccgca gcgacttcgc catcagggtg ccggccaggg
    13561 cgaacatgat ccccatcgac gggaagacca gcccggccca ggcccagccg aaggtgtggt
    13621 acgtgacgac gcggaccagg gcggcggcgc gcagggcgtc gaagtagcgg tcccggcccg
    13681 cggtgtccgg gggccccggg gagtgcgggg cgcgggccgg ggcggcgggc gcgggcggcg
    13741 ccgccgcctt gcggtgcctg cccatcaggc ggttcccgcc ggtgtgccca cttcccccgt
    13801 ccgtttcagt ttctgccagc gcagccggcc gccggtgagg gcggtgacgc aggagtggat
    13861 gaggacgagg tacatcatct ggcggtaggc gagctgctgg agcggcatca tcagcaggta
    13921 gcggtacttc tccccgtcga ggcggaaggc gtacgccgcg cagagcatct gcacggccag
    13981 caccgccagc cacgccagca gcgccgcacg gaagtcgatg aagatcatcg agtaggcggt
    14041 gaacacatcg atgagcgggg cgaagagcgg ggtgaggatc tggaagagga ccaccagcgg
    14101 cagcccgacc cggccgaagc ggcccgaggg cccccggtcg gtcagcgccc cgcggtgctt
    14161 ccacagggcc tgcatggtgc cgtaggacca gcggtagcgc tgggaccaca gctgtttcag
    14221 cgatcccggc gcctcggtcc aggcccgggc gtgctcctgg tagacgaccc gccagcccgc
    14281 gcggtgcagg gcgatggtga tgtcggtgtc ctcggcgagg gtgtcctcgc tcatgccgcc
    14341 ggcctggagg acggcctcgc ggcggaaggc gccgatggcg ccggggatgg tcggcatgca
    14401 gcgcagcagg tcgtacatgc ggcggtcgag gttgaagccc atcacgtact cgatgtgctg
    14461 ccaggcgccg atgagggtgc gccggttgcc gaccttggcg ttgcccgcga ccgcgccgac
    14521 ggacgggtcg gcgaagggct gcacgagctg ccgtacggtc tccggctcga agacggtgtc
    14581 gccgtccatc atcacgacga tgtcgtggcg ggcgtgccgg acgccgttgt tgagggcggc
    14641 gggcttgccc gcgttcgcct gccggacgac gcggacgtcc ggcaggccga gggactcggc
    14701 gatctccgcg gtgccgtccg tggagccgtc gtccacgacg atgatctcga tcgggtgggt
    14761 gctgcgcgcc agcgaccgga gggtgttggc gatgcactcc ttctcgttgt acgccgggac
    14821 gatcacgctc accggccggg tgacgggcgg tccccagccg aaccggcgcc tgttgcgccg
    14881 ccggtggtgg cggcgggcga ggaccagcat caggccgaag cggcccagga cggccacgcc
    14941 cacgaccacc agcccggccg agagcgccgg taccgtccac tcggcgacgg cgacggccgc
    15001 gacgagggcc ctgccctccc acagggtcgt gccggtggcc cggtggtggg cggcctggag
    15061 gccgcggccg gtgccggcgg cggcagcgcc ggggggcgtg ccgccctggg cggcaccggc
    15121 cgcctcctgc tgctgctgct ccatggcgcc gctgacggtg gtgaaggtgt agcccttcgc
    15181 cttcatcttc tcgatgtact tcggcagtgc cgcgatggtc tgcgaccggt cgccgccggc
    15241 gtcgtggaag agcacggagg cgccctcgcc gtcctcgggc gtggcccact ggacgatctt
    15301 ggagacgccc ggctccttcc agtcgtcgct gtcggtgtcg atgaagacgc tggtgtagcc
    15361 gtcctcgccg agttgctggt agacgggcca gctgtagtcg tcgatggcgt cggtctggga
    15421 ggagtacggc gcccggaaga gcgtggtggt gatgccggcc gcgcccgcga gggcgagctg
    15481 ggtctgctcc agctcacggg tgacgcggga ctcgctctgg taggagaggt cgacgtgggt
    15541 gaaggtgtgg acgcccacct cgtcgccctg ctcgaccatg tcccgcacga tgtccgggtg
    15601 gcgcgcgacc atcgagccga ccacgaagaa cgtgccgggc acgtcgtgct tctccaggat
    15661 cttcaggacc tgtggcgtcc aggtggggtc ggggccgtcg tcgaaggtga gcacgatcgt
    15721 cttgtcgggg acggagacgg tcgtggcccg cccgcccggg aaggtgagga tcggcccgcc
    15781 ttcgaggacg tcctccggta cgtcgtcggc gccggcgccg gcgcgtacgc gctggtcgtc
    15841 gccgacttcc gcgcgcagat agccgtcgag gaggagtacc gaggtcagcg cgagcagcag
    15901 gagcagggcg agcaggaccc gcggccgctg gagcgcggcg gccttgcccg cggcccgctc
    15961 gatccgggag ggggcgcggc ggcggcctcg tgagggtgtg gtcgtggtca tggaagcggc
    16021 ggcgtcccgg tcagtcggtg gcggatgcgg agggcgcgta cgtagcggag ggcgcggagg
    16081 gggtggaagg cgcggagggt gcggcggagg cgccgccggt cggtgcgggc gcctgcccgg
    16141 gcggctgcgc gccggcgggg ggagcaccgg tgggggcgcc gtttcccggg cgcgtctcgg
    16201 cgcccggcgc ccggccgtcg tcccgcccgc cgccgaaggg cagcagtgag gacgggctga
    16261 ccgaggtgcc gatgcccatg aaggccaggc ccagcacggt cgcgtaaccg agacagacga
    16321 ctccgaggag caggccgagc cggcgcagca gcctggcccg gcgcccggag gtgtcgacga
    16381 acacgggccc ctccgcggac ccgttgccgc gcttgcggcg gcggccgcgc acggcggcgc
    16441 ggctttcgaa ggcaggctcg gaatgcattc cccggaggct agggagcttt gcctgccgag
    16501 aactcgggct tcgctgtgcg gtcccgatga aaaacgcccc agtctgtccg ctgcctggga
    16561 gaacccggaa tttcgcgctc cgtgctcagg gaagacccag ccacgcgtgc gaggttcact
    16621 cctccggcca ggagaaacgg gccacaggaa cgggccgcca cgaggaacgg gagcgtacgc
    16681 catgaggagc acgaggactc cgaggagtac cgggggcacg aggagtgcga ggagtgcgag
    16741 gggcacgacg catgtccggc acccggcggc ggggctggcc ctgctgctcg tgctggccac
    16801 cgcgggatgc gccgcgcggg acggcgcggc ggacgcggcg gacgcggcgc cctccgcctc
    16861 cccctccgcc tccgctgctc cggccaccgg ctacgccccc tacgtcagcg ccaccaccgc
    16921 ctccgacctg gacaccgcgg gctcccccac gacgtacaac ctggcgttcg tggtctcctc
    16981 cggcagcggc tgcgtcccgc gctggggcgg cacccaggcc gtcgacgacc cggcggtggc
    17041 cgcccgtgtc gcggagctga aggagtccgg cgccaccgtc cgggtctcct tcggcggcgc
    17101 ctccggcaag gagctggcgg ccacctgcga cagcgcggcg gagctggccg aggcgtacgg
    17161 cgcggcgctg gacgcggccg ggtccacgcg ggcggacttc gacatcgagg gcgacgagct
    17221 gaccgactcc gcctcggtcg ccctgcggtc gcaggcgatc gcgctgctcc agcgggaacg
    17281 gagcggcctg gaggtctcct tcacccttcc ggtgatgccc tccggcctcg acgccgactc
    17341 cctggcgctg ctggagtccg ccaacgacca cggcgtccag gtctccacgg tcaacctcat
    17401 gaccatgaac tacggcgagt cctggaccgg ggacatgggc gactacgccg tcacctccgc
    17461 cgaggccgcc cacacccagc tgcagcgggt cttcggcctg tccgacgcgg cggcctggaa
    17521 gggcatggcc ctcacctcga tgatcggcgt caacgatgtc gccggggaga ccttcaccct
    17581 ctccgacgcg gcgcaggtgc gcgccttcgc caccgggaag gggatcgcct gggtgtcggc
    17641 ctgggcctcc ttccgcgacc ggcggtgcgg cgacgactcg gccggggagg acgcgtccac
    17701 cgagtgcagc ggggtggagc aggaggacgg ggcgttcgcc caggcgttct cggggtgagc
    17761 ggtacgggcc ccgacgggac ccggcccgtt cagcgccgcc ggtacaccag gcgccccgcg
    17821 acgacggtcg ccacgcaggc cgcggccccg cgttcggcga gcgcggcctc gtcggggacg
    17881 tcgaagacgg cgaaccgggc cgcggagcca cgctccctcg ggggtgcgaa cgtcaccggc
    17941 gcaccgcagg cgtacgggtc gagcgagggc accccgccgg ggcgtccgat ccggccgacc
    18001 accgcgagcc cggagcggtg cacggcgtcg cgcaccgcgc ggatgcgcag ttcgccgcag
    18061 gccaccgcca ccgtcccgtg gctcagcatg cgttgcagcc cgcgccgggc gctggctccc
    18121 cagcgggcct cgtcgggtgc cagggcggcc agcgcccggc cggtcagcgg ttcggtaccc
    18181 agctcgtcgg cctcgcgcgg gtcggggtgg taggcgccct ccagcagctc gtcgccgtac
    18241 gggttgacga gcccgggggt gaggatgccg ggccaccggc gcagcctggc ccccgggcgg
    18301 gcggcggcga cttcctccag ggggccggcc tcggcgatcc aggcgccttc gacggcgagc
    18361 gcccggcccc tggagtccgc gtggatcgtc agcacgggcg gggtcagttg gaggcgagca
    18421 gcttcagctc ggggtgcgcg gtcccgccct cgatcgccgt ggaggagatg tgcgagacca
    18481 cccggtcgtc gacggggtcg ttcgccgggt cgtcgtggac gacgaggtgc tcgtacgtcg
    18541 tggaccgctg ggccgggacg cggcccgcct tgcggatcag gtcgatgatc tccaggcggt
    18601 tggaccggtg cctggcgccg gccgaggaca ccacgttctc ctccagcatg atggagccga
    18661 ggtcgtcggc gccgtagtgc agggagagct ggccgacctc cttgcccgtg gtgagccagg
    18721 agccctggat gtgggccacg ttgtcgagga acaggcgggc gatcgcgatc atccgcaggt
    18781 actcgaagat ggtcgcctgc gtacggccct tcagatggtt gttctcgggc tggtaggtgt
    18841 acgggatgaa ggcgcggaag ccgcccgtgc ggtcctgtac gtcgcggatc atgcgcaggt
    18901 gctcgatgcg ctcggcgttg gtctcgccgg tgcccatcag catggtggag gtcgactcca
    18961 cgcccagccg gtgcgcgatc tccatgatct ccagccagcg ttcgccggac tccttcagcg
    19021 gcgcgatggc cttgcgcggc cgctcgggca gcagctccgc gccggccccg gcgaaggagt
    19081 cgagcccggc gtcgcggatg cgggtgatcg cctcctcgac gctcaccccg gagatccggg
    19141 ccatgtgctc gacctcgctc gcccccaggc tgtggatgac gagctgcggg aactccttct
    19201 tgatggcggc gaagtgcttc tcgtagtact cgacgccgaa gtcggggtgg tggccgccct
    19261 ggaacatgat ctgcgtaccg cccagttcga cggtctcggc gcagcggcgc aggatgtcgt
    19321 cgaggtcgcg ggtccagccc ttgtcgctct tgggcggggc gtagaaggcg cagaacttgc
    19381 acgccgtgac gcacacgttc gtgtagttga tgttccgctc gatgatgtac gtcgcgatgt
    19441 gctcggtccc ggcgtaccgg cggcggcgta cggcgtcggc ggcggcgccc agcgcgtgca
    19501 gcggggcgtc gcggtacagc gcgagcgcct cgtccggggt gatccgccca ccggcggcag
    19561 cacggtcgag gatgggctga aggtcggcct tctcggtcac cgggcgtccc tttcgtaagg
    19621 gttgtggacg gaccgaacca gcctacgcca gcccttttcc ggggccgacg tcaggcgccg
    19681 ccgagcccgg tccgccggac ccgttcctcg ccgccgcgga ccatggcgct ggtgcgctgc
    19741 ttgggcagcg aggcgctctc gcgggcggtc gtccgggccg gctccccggg gtccgggacc
    19801 ggcatcggcc gcaggcggtg gcgggggatc acccgccggg gcgggcgggt cagggtgatc
    19861 tggcgtacga gctgctggaa gcaggccagg gaggcgagcc ccggcagggt cgccgtcgcc
    19921 gcgtcgacga gcgtgacggg caactgggcg acgcacagga gcatcgccat gcaggagaag
    19981 aagaggacga cggaccagga gtggaccgcg cgccgctggt acagcgcggc gcgcagcacg
    20041 gagagggagg cgaccatcca cggcccgtag accaggaagg gccaccagga gaccatgtcg
    20101 ctcccggtcc gggacgcggc ggaccgcagc agggactcgt acgagaacac cccgccgaac
    20161 acgctgacgg cgcaggcgat ggccgccacc gaggcggcga ggaagtggct gaccgcccgg
    20221 cggccgttga tcctcctggg ctcgcgcacc ttgcggtgcc ccttcgggga gtccttcagc
    20281 gggggcagtt ccgccgtgat ctcctggagg ttgcccaggg gcgtgccggg ggcgggggcg
    20341 gtgaccgacg cctccgggta ggggtcgccc gggggctgct cctccagggc gtcccgcagc
    20401 atgaaggcca gctcttcggc ggggtcccag ttccagtcgg gcggcatcag atgaccggtg
    20461 aacgcttcgg cgggtcgccg gtgccggccg gtgcccatgt cgttggacgt ctgcatgttg
    20521 gtggccgagt gctctcgtcg tgggtcgatt cgtccgtggt acatgacacg cggcccgtca
    20581 ttccgccgac gagagggcgg atgcgtcctg gggggtgccc catcgccggg cgggatcgga
    20641 ttcggattcc agctccgtcg tcaccgtcgg aaaatgccgc ggaatgggtt cggtcacctg
    20701 tagcgtgacg gggagcccgt cccgggtcgg agttctaccg gcagtgcgta cggagtgcgc
    20761 cggggcggga aagtaggtgt acgggcccag catgaccgcg ggccctgtac tcctgttccc
    20821 tcggtgcggg ctggagatca gacccaggag accgtccctg gctgccttcg tcatatcccg
    20881 actaacgccg ccccactcca ccggatgcgc ggcaaatggg tgaacgatta cctgtataag
    20941 taatctcttc gcagggtcgt tcaggcggga tatgcggata gcggaacagc ccatctacgc
    21001 cggtacgagg aacgggaacg ggccgtggcg gcaggcgccg gccagcaccc cgagcaaggc
    21061 cccggcgatc aggaacggcc cgtacgggac ggcggtcccg cgtccgcccc gccgcacggc
    21121 gaccagcgcc cagccgtaca gcgcgccgag caggagaccg gccacggcgc ccagcgccag
    21181 cgtcgcccag ccgtaccagc cgaggacggc gcccgcgccg agggcgagtt tcacatcgcc
    21241 gaagcccatg ccctccgggt tgaggaggaa gagcacgaag tagccgccgc cgagggcgag
    21301 gctgcccagc agggcggtgg tccaccctcc ggcgtgtccc ggcacccgcg cggccaggcc
    21361 gaggagggcg agtgcggcac cggcgagcgg gagggtgagg aggtcgggca gccgccgcac
    21421 ccggaggtcg acggcggcca gcagcacacc ggcgggggcg agcagcagcc agacggcgag
    21481 ttcggggcgg gggccggtgg cggcggcgag ggcggcgcag accaccaggg tggcggtggc
    21541 gaaggcgggg gcgcccggac cgtacgacgg tcccgtcccg gagccgggcg gcgctcccgg
    21601 cggtgcttgg ggcggtgctc cggccgccgc gcacggcccg caccgcgccg ggccgagcca
    21661 gccgcggacc gggtgcccgg ccgggcactc cgtccgccag gattcgtcgg gcggtacgga
    21721 gaaccggtag gcggcgcgcg gcagcagcgc gcccgtcgcc gcgccccaca gcgcggcggc
    21781 gacgacggcc ggcaggacgc tcatcccgct gccgcgccac cgtcgcgccg ggtcggcggg
    21841 gcgggcggga cgcgttcggg cccgccctca cggggccggt gcgggcgggc ggtgcggcgt
    21901 cgcggcatgg cgggcttcct ggcgggtccg gggcgagggg ccggcgggcg cgccgagcct
    21961 actgccccgg caccggacgg ccagggggaa agccgggagc accgcgcacg ggcgatggcg
    22021 tacccggccg gacgccccgg aaaacggcga ggccccggtc cgtgaaggga ccggggcctg
    22081 gcacgactcg tcagagagcg gcgacgtggg cgaccacatc cgccgagaca ccctcgacgt
    22141 tcacaccgac gccgacaccg gcgcacacgg cggcgacggc gtcgacctcc gcgaaaacgc
    22201 ccgcggaagc accggccgcg aggccaccgg cgatgttgtc caggtccgcc tcggacatct
    22261 cggccgtctc aacctggggg gtgaggttca cgacgcacaa ttcccttcgt agaaacaaat
    22321 tgacaacggc ggatctcgcc gaggttcacg aatttctcgg attcccgaac ggggctcgtc
    22381 gccggcgttc cgcgtgccga gatcaaagca cgacgccgga gagacggcca gtcaccgggt
    22441 gtccgtgccc ggattcaccg ggtaaccaat ttcaccagcg tgaggaaaac atcaccgaat
    22501 acccccggtt tccttcacac cgtccggggc cccgcggaac cggcgggcgg gtggccggcg
    22561 atcccggcgc ggacgggtcg tggcaaatcg ggcagcgagt cccgtaattg actggcgttc
    22621 agttcggaga tgaggcaccg gtgaacagtg tgcagatccg tcggattttc cgggacggcg
    22681 gcgaggcggg cgggcggatt cccgcccggg cgggccacca tcggcccccc cggctcccgg
    22741 cgggacccac cgggacccgc ccgctccccc gtcacggctg ggtcacggct ggagcagctc
    22801 caccttcacg tccgccggga agcccgtcgt cgggccgacc cggcgggcga actcggcgac
    22861 cgcctcgagc tgcggggccc cgaagcggaa gtccagggtc ttgaagtacc gggcgagggt
    22921 cccctcgtcg aacgcctccc agcgggccgc ctgctcggcg accttgtcga cctcctggag
    22981 ggagaggttg cgcgaggcga ggaacgcctc gtgcaccttg cgcgtgatga ccggctcgcg
    23041 ctccaggtag tcgcgccggg ccgcccagac cgcgaagacg aacggcaggc ccgtccactc
    23101 cttccacagc gcgcccaggt cgtgcacgtc caggccgtag cgcgggccgt cgagcatgtt
    23161 ggcgcgcagc gccgcgtcgc cgatcaggac ggccgcctcg gcctcccgca tcatcaggcc
    23221 caggtcgggc gggcaggtgt agtagtcggg ccgtacgccg atccgctcct ccagcagcag
    23281 ccgggcgagc cggacggagg tgcgcgaggt cgagcccagc gcgacccggg cgccgtccag
    23341 gcgctccagc gggacctgcg agacgatcac gcacgacatc accgggccgt cgcagccgac
    23401 ggcgatgtcg gggaaggcga cgagccggtc ggcgtgcttg aggaactcga ccagggtgat
    23461 cggcccgatg tcgaggtccc cccgcacgag ctgctcgctg agcttctccg gggtgtcctt
    23521 ggtcagctcg aagtcgagga gcgtgcccgt tctcgcgagc ccccagtaca ggggcaggca
    23581 gttcaggaac tggatgtggc cgacacgcgg ccgggtgcga gaattgtcca catcgcgagg
    23641 ctagccctcg tcccccgcgg tccggcgccg gcccggcagc ggcccggccg tccgccgggc
    23701 gggtggaacg ttcaaacatt cgggtgacgt gatcttgacc tctattgctt tccggtgccc
    23761 gcgtgctacg ctcacagcaa gttgcagttt ggtttccctt gcagtacaga gcctgcggag
    23821 catgtgaccg cgggctctcg tcgttcttgg acgtatgcag ttgtgcagaa ttcaactctt
    23881 cacacttgct ggttctggag cagggcaacc cttttgagcc caaggagggc ttatggctac
    23941 cggaaccgtt aagtggttca acgccgaaaa gggctttggt ttcatcgccc aggagggcgg
    24001 cggccccgac gtcttcgtcc actactccgc gatcaacgcg tccggtttcc ggtcgcttga
    24061 ggagaaccag caggtgtcct tcgacgtcac gcagggtccg aagggcccgc aggctgagaa
    24121 cgtcaccccg gtctgataag cagtacccaa ggagccccgc gccgttccgg cgacggggct
    24181 cctgcccttt cccgccgctt tccggggccg ccccgtccgc ttccggcccg tccctcgggc
    24241 cgccgccccg gtgaattccc ggcgaattct tctcatacgt gctgcatgat cagtacgaac
    24301 gtcgtccccg gttccagcgc ttggtaggtg tgcggcacat ctccgcgata cgccatgtag
    24361 tccccgggcc ccagctctac gctctcgccc cgaggccccg ccttcatccg tcccgtactg
    24421 acgacgagat gctcgaccgt ccccggaatg tgcgggtccg attcccgtgc cgggcccggc
    24481 tcggcccgca tgcggtagat gtcccgccgg gcgccgggcg ggcaggcggc cagcagcgtg
    24541 ccgacgaagc tcgcccgttc cgacgtgacc tggggcccct ccccggcccg gatcacctgg
    24601 accgacgaca ccggcggctc caccagggcg ctgaacggca cccccagcgc caccgcgagc
    24661 gcccagatgg tctccatgct cgggttgccg cccgccgcct ccagctgcga cagggtggac
    24721 ttggcgatgc cggcccgctt ggccagctcg gacagcgaca gcccggcccg ggtccgttcg
    24781 cggcgcaggg aggcggcgat ccagtcgagg ggcaggcggg acgggagggc ggcggcgtca
    24841 tccggcatgt cgttcgctcc atcggtacga tcgttcgtct tgacgaacag gggtctcgct
    24901 gtccatcgta gaaaacatgc gttcggcaca gcgaacaagc gggaactccg cctccccgcc
    24961 gcctcctccc tcgcccgccc gtgatcccga gcttctccgg gacgtcgtcc tcgtcggtct
    25021 cgccggtggg atcgtcggcg tgtcgttcgg cgccatctcc gtcgcgggcg ggctgccggt
    25081 gtgggtgccc gtggtgatgt cactggtggt gtacgcgggt tcggcccagt tcagcgcggt
    25141 cggcgtgctg ctcgccgggg gcggtccgct cgccgcggcg gcgacgggcc tgctgctcaa
    25201 cacccggctg gcggccttca gcctggcagt cgccgggatt ctcggccggg gatggccgtc
    25261 gcggctgctg ggagcccatc tggtcaccga cgagacggtg gcgttcgcgc tcgcccagca
    25321 ggacccgggg cgccgccggg cggcgttctg gctctccggc tgcgcgctgt tcgcgctgtg
    25381 gaacgtgggc gtcctggccg gggcgctggc cggtaccgcc ctcggcgaca cggccgtcta
    25441 cggtctggac gccgccttcc ccgccgtcct ggccgccctg gtgctccctg cgctccgcga
    25501 ggacgcaagc ctgcgccggg ccgccctgcc cggtgccgcg ctggcgctgg cggtgacccc
    25561 ggtcgtcccg gcgggggtgc cggtgctgct ggcgctggcg gggctcctcc tccaccgcgg
    25621 tggcgcccgg cccgaggggc ggcctgcgtg aacgcgacgg tggcggtgat cctggcgctg
    25681 gcggccggga cgtacgtcct gcggctggcc ggcccggtgc tgcacggccg ggtcaccctc
    25741 ccggcgcggg tgcgggagct gctgtccgcc ggggcggtgg tgctgctggt cgcgctgctg
    25801 gccaccgggg cgctgaccga gggcgggggc ttcgcgggct gggcgcgtcc ggccggggtg
    25861 ctggcggggg ccgtactggc ctggcggcgg gcgccgttcg cggtcgtcgt cctgggcgcg
    25921 gcgggcgtgg cggcgctgct gcgggcggtg ggggtggagt gaggacggaa atgagtaccc
    25981 ggcccggccg tcggtggcgg ccggggggtg ggcgggggcg cggcccggct gtcggtggcg
    26041 gccggtaggg tccgcgccca tgaccgacac cgatcacctc accgccaccc gcaccttcta
    26101 cgacgccatc gccgaggact acgccgagca cttccgcggt caggtggccg gcgcgcccca
    26161 ggacctggag gtgctcgccg ccttcgcccg gctcgtcgga ccgggggccg aggtcgccga
    26221 cctgggctgc gggcccggcc gggtgaccgc tcacctggcc gggctggggc tgcgcgtctt
    26281 cggcctggac ctgtccgcct cgatgctcgc cgtcgcccgc cgcgagaacc cgcacctgcg
    26341 cttcgaacag ggctcgatgc tggagctgga ccggccggac gggtcactgg cgggcgtggt
    26401 ctcctggtac tccagcattc acaccccggc ggaggaactc ccggacctgt tcgccgagtt
    26461 ccggcgggtg ctggcgcccg gcgggcatct gctgctcgcc ttccaggccg gtgacgcgcc
    26521 gctccgcctc gaccggccct tcgaccgccc ggtcggcctc gacttccagc ggcggcggcc
    26581 ggagcgcatg gccgggctgc ttcaggacgc cggtttcacc cttcactcgc ggacgctgcg
    26641 ggaaccgggc gagacggagt cggctccgca ggctttcctg atcgcccgcc gctgagctcg
    26701 ggcaccaggg tggccaggcc caccagggcc agggcggcgc ccagccagag gggagcgcgc
    26761 aggccccaca cgtcgatccc gacggccccg agcgaggagc cgacgatgat gccgagggtg
    26821 atgaaggagg agtggacggt gttcaccagc gggccggcgt tgccggtccg ctggacccgg
    26881 gtgatcatcg ccgggttcat ggtcacgccg accaggccga tgcccagcat gcacagcacg
    26941 gccggtgccg gcagatcggc gaggagggcg aagcccgcca ggaacatcgt gttcaggacc
    27001 agaccggcgg ccaggaccgg gacggcgtac cggtcggcga ggcggccgac gacggtgttg
    27061 ccgaccacgg tggcggcgcc gtaggcgatg agcagcaggg ggacggtgcc cgcggagaag
    27121 ccggtgacct ccgtgaggat cgggttgagg tagctgaagg cggagaaggt ggcgccgatg
    27181 accagcatgc tggtggagag caccagccac agcttcgggt tgcggaagac accgatctcc
    27241 tgccggaagc cgccctcgct cgcggcggct tccaggcgcg gcacgcccac c
//
