LOCUS       LN831790               27945 bp    DNA     linear   BCT 17-JUN-2020
DEFINITION  Streptomyces leeuwenhoekii strain C34 (= DSM 42122 = NRRL B-24963)
            genome assembly, chromosome: chromosome.
ACCESSION   LN831790
VERSION     LN831790.1
KEYWORDS    .
SOURCE      Streptomyces leeuwenhoekii
  ORGANISM  Streptomyces leeuwenhoekii
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-02-26 04:50:55
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 5315120
            Orig. end    :: 5343065
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..27945
                     /aStool="rule-based-clusters"
                     /category="saccharide"
                     /contig_edge="False"
                     /core_location="[10000:17945]"
                     /cutoff="20000"
                     /detection_rule="minimum(2, [Alpha-amylase,
                     Alpha-amylase_C, Bac_transf, CBM_48, Capsule_synth,
                     DegT_DnrJ_EryC1, Epimerase_2, Glyco_tran_28_C,
                     Glyco_transf_28, Glyco_transf_8, Glyco_transf_8C,
                     Glyco_transf_9, Glycos_transf_1, Glycos_transf_2,
                     Glycos_transf_4, MannoseP_isomer, PIG-L, Poly_export,
                     Polysacc_synt, Polysacc_synt_2, RmlD_sub_bind, Wzy_C,
                     dTDP_sugar_isom])"
                     /neighbourhood="10000"
                     /product="saccharide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..17945
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="minimum(2, [Alpha-amylase,
                     Alpha-amylase_C, Bac_transf, CBM_48, Capsule_synth,
                     DegT_DnrJ_EryC1, Epimerase_2, Glyco_tran_28_C,
                     Glyco_transf_28, Glyco_transf_8, Glyco_transf_8C,
                     Glyco_transf_9, Glycos_transf_1, Glycos_transf_2,
                     Glycos_transf_4, MannoseP_isomer, PIG-L, Poly_export,
                     Polysacc_synt, Polysacc_synt_2, RmlD_sub_bind, Wzy_C,
                     dTDP_sugar_isom])"
                     /neighbourhood="10000"
                     /product="saccharide"
                     /protocluster_number="1"
     cand_cluster    1..27945
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(2, [Alpha-amylase,
                     Alpha-amylase_C, Bac_transf, CBM_48, Capsule_synth,
                     DegT_DnrJ_EryC1, Epimerase_2, Glyco_tran_28_C,
                     Glyco_transf_28, Glyco_transf_8, Glyco_transf_8C,
                     Glyco_transf_9, Glycos_transf_1, Glycos_transf_2,
                     Glycos_transf_4, MannoseP_isomer, PIG-L, Poly_export,
                     Polysacc_synt, Polysacc_synt_2, RmlD_sub_bind, Wzy_C,
                     dTDP_sugar_isom])"
                     /detection_rules="melC"
                     /kind="neighbouring"
                     /product="saccharide"
                     /product="melanin"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..27945
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="False"
                     /product="saccharide"
                     /product="melanin"
                     /region_number="33"
                     /rules="minimum(2, [Alpha-amylase, Alpha-amylase_C,
                     Bac_transf, CBM_48, Capsule_synth, DegT_DnrJ_EryC1,
                     Epimerase_2, Glyco_tran_28_C, Glyco_transf_28,
                     Glyco_transf_8, Glyco_transf_8C, Glyco_transf_9,
                     Glycos_transf_1, Glycos_transf_2, Glycos_transf_4,
                     MannoseP_isomer, PIG-L, Poly_export, Polysacc_synt,
                     Polysacc_synt_2, RmlD_sub_bind, Wzy_C, dTDP_sugar_isom])"
                     /rules="melC"
                     /tool="antismash"
     gene            355..1287
                     /gene="sle_45170"
     CDS             355..1287
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VW81"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VW81"
                     /gene="sle_45170"
                     /product="Integral Membrane Protein"
                     /protein_id="CQR63975.1"
                     /transl_table=11
                     /translation="MSPLTEPAARPGPPAGTGPTDGTAAASGPLAEAAPGYRPGRTLPL
                     RVELVRQLGRRRTLIMGAILAALPFVLLVAFAIGGEPDGPGDRVTLMDTATASGANFAA
                     VSLFVSAGFLLVIPVALFCGDTVASEANWSSLRYLLAAPVPRARLLVSKLAVGLGLSLA
                     AMVLLPLVALAVGTVAYGWGPLELPTGGSLDPGTAAGRLAVVVAYLFVSQWVTAGLAFW
                     LSTRTDAPLGAVGGAVGLTIAGNVLDAVTALGHWREFLPAHWQFAWADAVQPRPEWSGM
                     IQGAALSLTYALVLFALAFRGFARKDVVS"
     gene            1645..3570
                     /gene="sle_45180"
     CDS             1645..3570
                     /NRPS_PKS="Domain: AMP-binding (55-507). E-value: 3.5e-91.
                     Score: 297.6. Matches aSDomain:
                     nrpspksdomains_sle_45180_AMP-binding.1"
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W4M6"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="InterPro:IPR042099"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W4M6"
                     /gene="sle_45180"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     260.8; E-value: 3.2e-79)"
                     /gene_kind="biosynthetic-additional"
                     /product="Long-chain-fatty-acid--CoA ligase FadD15"
                     /protein_id="CQR63976.1"
                     /sec_met_domain="AMP-binding (E-value: 2.3e-86, bitscore:
                     288.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVRKELKRARQRGDLAARSRPEIVRDGGGTVREVRTAPLAPRPR
                     TGSTADIPFTNAAEDPGAVVLRRERAGTWQPVTAAEFAREVTAVAKGLIAAGLEPGGRV
                     AVMSRTRYEWTLLDFAIWAAGGQTVPVYPTSSAEQVEWIVRDSGAGHVVTETAEHTATV
                     LTGTAGHPGPPRTWQLDAGAIADLTALGRGLPDEEVTKRRTALTPDTVATICYTSGTTG
                     RPKGCVLTHANLHAEAANTVELLHPVFKAVTGRTASTLLFLPLAHILGRTLQIACLAAR
                     IELGHCPSIKPAELRPALKSFRPSFLVGVPYLFEKIHDTGRATAEKLGRGASFDRAHRV
                     AVRFGEAHLARFLGTGKGPGPGLYAAWALYDLLVYRRVRKELGGRTRYAISGGSPLDRD
                     LNLFFYAAGIVVYEGYGLTETTAAATLVPPLAPRPGTVGLPVPGTAVRIADDGEVHIKG
                     GIVFGSYRNDPEATDAVLDDGWFATGDLGSLDEDGYLTITGRKKDLLVTSGGKNVSPAV
                     LEDRLRSRPPVAQCVVVGDNRPFVAALITLDPEAVAHWLAVRKLPAGTPMSEVIRDPRM
                     RADVQKAVDHANEAVSRAESIRAFALVEGEFTEENGLLTPSLKVKRQAVATAYAAEIEA
                     LYAPGR"
     aSDomain        1810..3165
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sle_45180_AMP-binding.1"
                     /evalue="3.50E-91"
                     /label="sle_45180_AMP-binding.1"
                     /locus_tag="sle_45180"
                     /protein_end="507"
                     /protein_start="55"
                     /score="297.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="NAAEDPGAVVLRRERAGTWQPVTAAEFAREVTAVAKGLIAAGLEP
                     GGRVAVMSRTRYEWTLLDFAIWAAGGQTVPVYPTSSAEQVEWIVRDSGAGHVVTETAEH
                     TATVLTGTAGHPGPPRTWQLDAGAIADLTALGRGLPDEEVTKRRTALTPDTVATICYTS
                     GTTGRPKGCVLTHANLHAEAANTVELLHPVFKAVTGRTASTLLFLPLAHILGRTLQIAC
                     LAARIELGHCPSIKPAELRPALKSFRPSFLVGVPYLFEKIHDTGRATAEKLGRGASFDR
                     AHRVAVRFGEAHLARFLGTGKGPGPGLYAAWALYDLLVYRRVRKELGGRTRYAISGGSP
                     LDRDLNLFFYAAGIVVYEGYGLTETTAAATLVPPLAPRPGTVGLPVPGTAVRIADDGEV
                     HIKGGIVFGSYRNDPEATDAVLDDGWFATGDLGSLDEDGYLTITGRKKDLLVT"
     CDS_motif       2278..2337
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sle_45180_0001"
                     /evalue="5.50E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="sle_45180"
                     /protein_end="231"
                     /protein_start="211"
                     /score="25.1"
                     /tool="antismash"
                     /translation="ATICYTSGTTGRPKGCVLTH"
     CDS_motif       2998..3066
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sle_45180_0002"
                     /evalue="2.10E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="sle_45180"
                     /protein_end="474"
                     /protein_start="451"
                     /score="13.7"
                     /tool="antismash"
                     /translation="GEVHIKGGIVFGSYRNDPEATDA"
     gene            3753..3983
                     /gene="sle_45190"
     CDS             3753..3983
                     /codon_start=1
                     /db_xref="InterPro:IPR005528"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W2B6"
                     /gene="sle_45190"
                     /product="Hypothetical Protein sle_45190"
                     /protein_id="CQR63977.1"
                     /transl_table=11
                     /translation="MKRSAAVVTGTVVALGGSAAPAFADAVAEGAATGSSGGLTGQVVQ
                     VPVHIPINVCGNTVNGVGLLNPAYGNKCTND"
     gene            4192..4851
                     /gene="sle_45200"
     CDS             4192..4851
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VZE5"
                     /db_xref="InterPro:IPR005528"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VZE5"
                     /gene="sle_45200"
                     /product="Hypothetical Protein sle_45200"
                     /protein_id="CQR63978.1"
                     /transl_table=11
                     /translation="MNVPGASSGNTVQAPDHAPADPCGDTAHATDVLDTVFGDACADEP
                     EETSADHDPEPERDPDSHDSGPGDVVSELLGQAQAVASADEGSRSTVQITDEESGLFCG
                     ALADAMSTLSLVTCADEDGGYGDDGYGDGGYGDGATPPVDHTPKETPPPADDKVTPPAE
                     VKPPAADVEPPADDEDPPSLAETGAGALLSTAAVSTVLLAGGAVLYRRGRRTMPRQ"
     gene            complement(5107..6414)
                     /gene="sle_45210"
     CDS             complement(5107..6414)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VTV4"
                     /db_xref="InterPro:IPR011761"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VTV4"
                     /gene="sle_45210"
                     /product="Conserved Hypothetical Protein"
                     /protein_id="CQR63979.1"
                     /transl_table=11
                     /translation="MSLFDTGVPAVLLRIDRNPFHHGTLGAVRSLGRAGVAVHVVADCA
                     KSPVGASRFVRRVHTPPPPGASPAEIADVLRRVAARIARPAVLVTMDDASAIAVARMRA
                     ELAPAYLLPAAPGTLPGRVADKAELAGLCAALDVPHPVTVVPDSPAEAASAACRLGLPL
                     VAKWSRPWLLPADSGLRSTVLVRSAQQARELYLRSGEAGCRLLLQAFLPPGADRDWFAH
                     GYADRTGAVRAGGCGRKTRARPRGAGLTAAGCWTPNAEVQALTERITGALGYRGIFDLD
                     FRRCGSTGRYHLLDFNPRPGAQFRLFADGSGLDVVRALHLDLTHRPLPEGAPLPGRVFV
                     VENYAPLTVLRPAPGGRELAWHARDDRAPGRALWALWGRHAAGRLVRRSRRGEHPEAAA
                     CPAEGGVVPRAVRAPSVPGQAEPVEPAEPADLTGSR"
     gene            6628..8079
                     /gene="sle_45220"
     CDS             6628..8079
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VW84"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="InterPro:IPR017853"
                     /db_xref="InterPro:IPR022790"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VW84"
                     /gene="sle_45220"
                     /product="Secreted Protein"
                     /protein_id="CQR63980.1"
                     /transl_table=11
                     /translation="MSPQQPRARSGRLAFVAASVAASAVLAAGPGFAAGAGPARAAAPL
                     APAVAGPAADPVPGTPAIPAAPPVPQLTQAPPAANEPKDPKDPRDPKDPKDPRDPKDPK
                     DPRDPRDPRDPGDPKDPKDPKDPKDPRERTPAFGAYLHYGSPGVTRMDELSRWLGGAEL
                     RVGHTYLPGDRWSNIAGAPGFLDEWARWRNGKPDRIFVLNVPMLERNEEGVPDDEVRRL
                     LRAGAAGRFDHHFRALGERLVRLNAPDTVIVLGWEMNGITYTHRCGPDPAAWKTYWNRI
                     VTTMRSVPGQKFRFDFAPSRGRDAIPWTECYPGNDTVDIIGMDAYDQPRGMSFDEQVAE
                     PYGLRAHVEFAKAHGKPISYPEWGLFRNGDNAAYVQGMLAWMDEHQALYHTLTDYCPHG
                     VWQCDRNPRSAAAYRAVLSARTGDPGAPPAPVPAPAPLPVPTPAPAPQPSRPATGCSSL
                     SLGGWVERWLVGALCTRLDRWSRDG"
     gene            complement(8104..9222)
                     /gene="sle_45230"
     CDS             complement(8104..9222)
                     /codon_start=1
                     /db_xref="InterPro:IPR016181"
                     /db_xref="InterPro:IPR038740"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W4N0"
                     /gene="sle_45230"
                     /product="Conserved Hypothetical Protein"
                     /protein_id="CQR63981.1"
                     /transl_table=11
                     /translation="MRYPAYTTELVTGERAFAALAPEWSRLYRRCATATPFQSHAWLHS
                     WWLSYGRRGRLRLVLVREGGELAAAAPLMRVRRPLPALVPLGGCLSDYGDVLVDDEHGD
                     AAVAALTEALYAAARTALVDLREVRPGGAAERVHDRWRGPRRRLGDSLCLELPAVPMAE
                     LVARLPSAKAQQRVRAKLRKLDALGVKSRAVLPEEVDAALGRLLELHRLQWQGRKVTGE
                     HLKPRFREHLVRAVGPMVRSGDAVVTEFRMADEVVAVDVTLRSPALAGGYLYGAHPRLR
                     ECRADVAVMLLDACGRHVTGGERAGGTLSLLRGNEPYKHHWRPEPVVNQRLLLARRRTA
                     PLLAAAAGGDAARRRGKVALRRWRERGGGGGP"
     gene            complement(9219..10004)
                     /gene="sle_45240"
     CDS             complement(9219..10004)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W2C1"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W2C1"
                     /gene="sle_45240"
                     /product="Conserved Hypothetical Protein"
                     /protein_id="CQR63982.1"
                     /transl_table=11
                     /translation="MTENVTDDVTDDVTENWNENRSGTRTRGVRAAGAIGTGTARPALP
                     AASAAGRTRATVRARARTLPPWSVLAAGALAGGLLGGGYGLVRTPDYTATSYVVAVPAR
                     DADPASALGFAQAYGRVATQVAVLADAQVGAGVPAATLKRSVRTATSPDAPMVAVSATS
                     HRPDLAADMANAVSEALTRHAGNASGSTHVTLRSFARATRPTEPSSAPAGLAGLVGASA
                     GGLLGGLALLVRPRRAAAGSGRAAAVPAPATAADVRGQS"
     gene            complement(10001..11155)
                     /gene="sle_45250"
     CDS             complement(10001..11155)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VZE8"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="InterPro:IPR028098"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VZE8"
                     /gene="sle_45250"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     saccharide: Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 150.4;
                     E-value: 1.3e-45)"
                     /gene_kind="biosynthetic"
                     /product="D-inositol-3-phosphate glycosyltransferase"
                     /protein_id="CQR63983.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 2.2e-16,
                     bitscore: 58.6, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVLHVITGLGVGGAEQQLRLLLRHLPARCEVVTLTNPGPVADGL
                     RADGVPVVHLGMTGNRDLSALPRLTGLVRAGGYDLVHTHLYRACLYGRLAARLAGVRAV
                     VATEHSLGETQMEGRPLTAGVRALYLTGERLGSTTVAVSPTVAARLRRWGVPASRIEVV
                     PNGIDLARFRFDPVRRHRTRRRLGLPDDAFVVGGIGRLTPGKRFDVLVRALARLPGDCR
                     LLLVGGGPDEHVLRREAREAGVADRVLLTGERPGLPDGSPGPDLPSLACAMDVLASPSP
                     EEAFGLAAVEGLASGLPVLYAACPALEDLPPHTAPAARRVPGGAEEFGRALAEVRAAGP
                     GPRTAPKAARHYCITRSAARLMDVYATALARHSLSPAPQGVSSA"
     gene            complement(11168..11857)
                     /gene="sle_45260"
     CDS             complement(11168..11857)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VTY7"
                     /db_xref="InterPro:IPR002509"
                     /db_xref="InterPro:IPR011330"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VTY7"
                     /gene="sle_45260"
                     /product="Putative polysaccharide deacetylase yxkH"
                     /protein_id="CQR63984.1"
                     /transl_table=11
                     /translation="MYHSVGDCSDDPYRITVTPGRLDAQLGWLRRRGLRGVSLGELLAA
                     RARGEGRDLVGLTFDDGYADFVEHALPVLRRRGCGATLFVLPGRLGGVNAWDPLGPRKP
                     LLTADGIRRAAAEGVEIGSHGLTHVDLTRADDATLRAEVARSRALLTELTGTPVAGFCY
                     PYGTVDRRAADAVRDAGYTYGCAIDPGPLTGPYALPRVHVGQRDTAVRLLLKTRLHRLR
                     RRAAEGI"
     gene            complement(11979..13760)
                     /gene="sle_45270"
     CDS             complement(11979..13760)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VW88"
                     /db_xref="InterPro:IPR004268"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VW88"
                     /gene="sle_45270"
                     /product="Virulence factor mviN"
                     /protein_id="CQR63985.1"
                     /transl_table=11
                     /translation="MTVTPPRAGDAAAVPAPRTPTAPDAAGGERAAGSPRFLARAALLT
                     AALSVAASVLGLARDQALARLFGAGSETDAFLVAWTVPEFAATLLIEDGLAFALIPMFS
                     LALARRARGAPGDPVRALVTTTLPRLALAFSTVAALAVVLAPQLVRALAPGLPGHDLAV
                     ECTRLTATCVLSFGLAGYCSAALRAHRRFLAPAAIYVAYNTGIITAMVVLGDRLGVRSA
                     AVGVAAGGCLMVAAQLPSLLRQLRRRDDAGRPEAATDDGTCPPALALFATVLLFALCRQ
                     SQVLIERFLAAGLPAGAISHLNYAQKVAQIPMTLSLMLCTVTFPVVARALAEGDTARAR
                     ARVERDVALAACVVLLGAATVVACAPQIVEVLFQRGAFTAGDTAATAGVMRVYALGLLG
                     QTVVGALARSYFSAGRASWYPLGAMALGVAATAAIGACAAGPWGATGIAAANAAGITVT
                     AALLLAGMGERSVPIRVRRVLAGLGGPAGAAAGATAAGALAAGRCGPPALGLLVGAVTV
                     TAVFALLGRVLGVQGIAPAAGFLRSVVSRRHPHDCFPRSHRLQRFHRSQRFLHFLRFLR
                     FRGLLRSLRFLRFHRFR"
     gene            complement(13757..15304)
                     /gene="sle_45280"
     CDS             complement(13757..15304)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W4N5"
                     /db_xref="InterPro:IPR007016"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W4N5"
                     /gene="sle_45280"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     saccharide: Wzy_C"
                     /gene_kind="biosynthetic"
                     /product="Integral Membrane Protein"
                     /protein_id="CQR63986.1"
                     /sec_met_domain="Wzy_C (E-value: 6.1e-14, bitscore: 51.0,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHALPPHRPAHRCPPGPGARALPPVLAVVAVVALLAVEFAPGGA
                     GGPHPADAASALVVVYCAARLARDRRRPLTPAAAVVLALPVAGIALAALHAPSPAAGLT
                     GLVRYLQVFVLLPAAVALLVRERRDVRLLAWSLVGLALWQGAVGVHQYATATGASYQGE
                     PVRAVGTFGPQDVMGMATVVSLGLVAALGLALGHAPVRQRVVAAGCAVALLAPLAVSFS
                     RGAWIATAVACVVQLLLAGVRRALAVGAAVAACAVVLVGGLGLGTAMLQERLDSITRVA
                     DAPDQSVTDRYAMWAAAGGMWRERPLTGVGLKGFPEHRDAHASLALSSGSDTEGAGAAF
                     RRQPLLSPHNMYLLILAEQGLTGLLAFAGSWLALLVRGVREVRCRGAAARDCGLVACGL
                     LVWQLTDFAYADIGGPSTVLTAVSLGLAAWWAVGGGEDGDAAGPVTDGGTSAATGPGTG
                     GGGSLATGPGAGGRGGHRATAGAGAAGDCREGAAAGGTGGRAPSRAAGAGPQEAPAR"
     protocluster    15259..25813
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[20258:20813]"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      20259..20813
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="2"
     cand_cluster    15259..25813
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="melC"
                     /kind="single"
                     /product="melanin"
                     /protoclusters="2"
                     /tool="antismash"
     gene            complement(15310..16770)
                     /gene="sle_45290"
     CDS             complement(15310..16770)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W2C5"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W2C5"
                     /gene="sle_45290"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     saccharide: Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146:sugar transferase (Score: 252.5; E-value:
                     1.4e-76)"
                     /gene_kind="biosynthetic"
                     /product="Putative colanic biosynthesis UDP-glucose lipid
                     carrier transferase"
                     /protein_id="CQR63987.1"
                     /sec_met_domain="Bac_transf (E-value: 1.3e-58, bitscore:
                     196.1, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAESTVPSPAGQPRDLALSPLRILPPRTRGGGFALPARRPAARP
                     ASRLPLLAADGTAALLGSLTLTGAPDRPLLAAPLVAATLLLRPRGLPPVPAGVLDELPS
                     VCGRIAVAWLALAALLAAYTPHQALSADSLLLGFTVQAAAGCAGRGAVHWRRRTTLRNR
                     PRAALVIGPAGVAQRVAAAVLRHPRCGVRPVGVVTGGPFGSSLLGGPGTGAAGLPVLGT
                     EEEVRRAVARNGVREVLVVHPSVRTRQAPLLRALAASGCAVWEVDPRSPSSGSRDEIAG
                     FSRRRLEAGAGRPGGALGKRVLDVVVSGVLLLAAGPLLLACAVVLRVSEGPGVVFRQVR
                     VGQDGKPFTLLKFRTHRPVDEHESATRWSVADERRMPWFCRFLRRTSLDELLQLWNVFR
                     GDMSLVGPRPERPYFVTKFSETYPGYAARHRMPAGITGLAQIHGLRGDTSIEDRARFDN
                     AYIDNWSLWQDVCILLRTAVTLVRPTGS"
     gene            complement(16767..17945)
                     /gene="sle_45300"
     CDS             complement(16767..17945)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VZF1"
                     /db_xref="InterPro:IPR028098"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VZF1"
                     /gene="sle_45300"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     saccharide: Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 205.4;
                     E-value: 2.7e-62)"
                     /gene_kind="biosynthetic"
                     /product="Uncharacterized glycosyltransferase MJ1607"
                     /protein_id="CQR63988.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 7.8e-34,
                     bitscore: 115.4, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHLPATGPAPRVLHLTQPVDGGVARIVTDLARAQLAAGWDITVAC
                     PDGPLAASLRSLGAEVRPWPATRSPGPSLPAETWRLARIVEDVRPDLVHAHSAKAGLAG
                     RLAVRARIPTVFQPHAWSFEAVGGVPAVLALGWERWAARWAARVVCVSEAERRRGVSAG
                     IRGRWAVVPNGVDPDHFRPGPAVRPPLLADLGPRARLVVCVGRLCRQKGQDVLIAAWDR
                     IAERVPDARLVLVGDGPERARLRALAPASVRFTGAVADAAPWYRAADVVVLPSRWEGIA
                     LAPLEAMACGRPVVLTDVDGAREVLPPALAPHCLVPPTDPAALAGAVSALLLDPALRAS
                     TARQGRAHVLSAHDVRRTARAVAAVYGELLGGGPDAAGPAVVPTEYRESIQS"
     gene            18190..18501
                     /gene="sle_45310"
     CDS             18190..18501
                     /codon_start=1
                     /db_xref="InterPro:IPR005528"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VTZ2"
                     /gene="sle_45310"
                     /product="Hypothetical Protein sle_45310"
                     /protein_id="CQR63989.1"
                     /transl_table=11
                     /translation="MTLRRAFARMVVNPKEHLSMSRIAKGLVLTSVAAGAVTGTTGVAV
                     AADAGAGAGAKATAADSPGGLAGSAVQVPVYVPVNVCGNTVDVGGLLNPAFGNKCKNA"
     gene            18781..19638
                     /gene="sle_45320"
     CDS             18781..19638
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VW90"
                     /gene="sle_45320"
                     /product="Secreted Protein"
                     /protein_id="CQR63990.1"
                     /transl_table=11
                     /translation="MRLPARRIAASAFCATLLLAVTGPAATAADGDSVRERTSAASRAP
                     LPDVGALTAQVQSLSGLGGVVAPVSDLLGAVLKADDGRLTKEQAEQFSKAVEDALAKAQ
                     ATGMPIAPEAAAPGTTTPDTATPGTTAPGVGTPAQPPVALQPPAVAQPNDDAPATTLPA
                     PLAPAPLAPAPLAPAPAAPAAVAPAADESGTASTGLIGAALDALRKSIETLIGASTSAQ
                     PEQVSPAAAGVVTDVVNVVAATLFGGGLPAPDLAGLPPLPAAPNGTTPANTPADTPVNA
                     PATP"
     gene            19928..20209
                     /gene="sle_45330"
     CDS             19928..20209
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W4N8"
                     /gene="sle_45330"
                     /product="Hypothetical Protein sle_45330"
                     /protein_id="CQR63991.1"
                     /transl_table=11
                     /translation="MKPLKAAAAVAGSLALAGAAGPAYAHNDVAELTHAVDHVAGVVTE
                     EPVIGLPVESKPGESRTEDKSSALRTVKTLIDEVGSVGALLGGLPARG"
     gene            20259..20813
                     /gene="sle_45340"
     CDS             20259..20813
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W2D0"
                     /db_xref="InterPro:IPR010928"
                     /db_xref="InterPro:IPR023199"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W2D0"
                     /gene="sle_45340"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     melanin: melC"
                     /gene_kind="biosynthetic"
                     /product="Tyrosinase Co-Factor"
                     /protein_id="CQR63992.1"
                     /sec_met_domain="melC (E-value: 6.7e-40, bitscore: 135.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVSEREAARDAGREPADPAGGGPADATRRRLARRLLVPALAAAF
                     VPVAAAPGSPRPAKSAGDSKAARTDRRGTAGRARTATRPLAAPDDGAFDETYLGRRIRG
                     VRTPDAAGGPGSWHVTVDGRPLHLMRRADGTWMSMVDHSRSYPTPLEAARAAVDALPPG
                     QRLSGTGGGHGHGGGRHGVHA"
     gene            20797..21663
                     /gene="sle_45350"
     CDS             20797..21663
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VZF4"
                     /db_xref="InterPro:IPR002227"
                     /db_xref="InterPro:IPR008922"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VZF4"
                     /gene="sle_45350"
                     /product="Tyrosinase"
                     /protein_id="CQR63993.1"
                     /transl_table=11
                     /translation="MVYTRKDVSTLTRAERQRFVRALLEVKRRGEYDEFVRMHIEYFVP
                     DGEDGLRVAHMTPSFLPWHRQFLLELERALQRVDASVTVPYWDWTKDRRATSVPWTADL
                     LGGNGRSSDHQVTTGPFAYREGNWTLRYNITDTRFLTRDLGRRRAPIQLPTKSDLEWAL
                     KDPVYDAAPWDSTSSKGFRNKLEGWGPGRGSTSWRNHNRVHRWVGGVMVGGASVNDPVF
                     WLLHAFVDLQWSRWQRRHRTTRYLPAQPPGESNPQHGRIIARHQKLPPWDVTPDQLEDL
                     SHIYRYG"
     gene            complement(21770..21961)
                     /gene="sle_45360"
     CDS             complement(21770..21961)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VU14"
                     /gene="sle_45360"
                     /product="Hypothetical Protein sle_45360"
                     /protein_id="CQR63994.1"
                     /transl_table=11
                     /translation="MSPAPVLGLLPTEPGPVAGCATCQGLAREREAARAARDGSRVSDC
                     NVLIRAHPHGPRASGRGE"
     gene            22028..22270
                     /gene="sle_45370"
     CDS             22028..22270
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VW91"
                     /gene="sle_45370"
                     /product="Conserved Hypothetical Protein"
                     /protein_id="CQR63995.1"
                     /transl_table=11
                     /translation="MEGNTVTGTWTEQTAPDGYYRGARYFGALQMLVEPTGRRMAGKWV
                     GFGKEFDVNTGPWELRLMDTSTSKATLEAYSRPPE"
     gene            complement(22352..23245)
                     /gene="sle_45380"
     CDS             complement(22352..23245)
                     /codon_start=1
                     /db_xref="InterPro:IPR025668"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W4P3"
                     /gene="sle_45380"
                     /product="Transposase"
                     /protein_id="CQR63996.1"
                     /transl_table=11
                     /translation="MTTELDTLLTALYVHIDDHLKTPRRRGRPPKLTDAELITLAVAQA
                     MPGFHCEARWLRFAHAHLHGMFPCLPQRPAYNKRLRAALGLVKQAIRSLAADTDLWLDD
                     VWIVDSTPVECACSRETVKRSDLAGWAGYGYCRSHSRFYWGLKLHLVCTPAGLPVTWAL
                     ADPKIDERQILAALIDNEPHLAAHRPGLLILANKGYTATELDRFLAARGISLLRPSYRN
                     RTPRPGEALLKTVRQLIESVNDTLKGQLDLEQHGGRTIEGVGVRVAQRILAMTCAIWHN
                     RTIGAPVTRSLIACDH"
     misc_feature    complement(23231..23233)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(23413..23991)
                     /gene="sle_45390"
     CDS             complement(23413..23991)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W2D5"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR041583"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W2D5"
                     /gene="sle_45390"
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 55.9; E-value: 1.2e-16)"
                     /gene_kind="regulatory"
                     /product="TetR Family Transcriptional Regulator"
                     /protein_id="CQR63997.1"
                     /transl_table=11
                     /translation="MVRRNDQRRAALVDAAIEVLAREGARGLTFRAVDAEAAVPAGTAS
                     NYFASRDDLFTEAGARVYERLQPDEATIARQRAADRHRGTYAELMRELVGRIASFRTGY
                     LALLELRLEATRRPELRKVLTERVRADVDANVAYHEASGLPGDATAVKLLMLTLNWLIV
                     EQLTLPDVFTEEEREQLVTAAVERIVAAE"
     gene            24061..24654
                     /gene="sle_45400"
     CDS             24061..24654
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VZF7"
                     /db_xref="InterPro:IPR002734"
                     /db_xref="InterPro:IPR024072"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VZF7"
                     /gene="sle_45400"
                     /product="Dihydrofolate Reductase"
                     /protein_id="CQR63998.1"
                     /transl_table=11
                     /translation="MRKLVYYIGVSLDGRIAGPGGEFDFFPQGDEQQAAAYSTWMNALY
                     PETIPTAYRAAVGVADAPNRRFDTVVMGLGTYRLSVDNGITSPYAHLRQYVVSSTLKPD
                     TDPAVTVVPSDPRALIRELKGEMAAGPDIWLCGGGRLAGTLLPEIDELLIKTYPVVAGT
                     GILVVDGAFDPTVFNVAERTAFPNGVTLTRLTRR"
     gene            complement(24666..24965)
                     /gene="sle_45410"
     CDS             complement(24666..24965)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VU21"
                     /db_xref="InterPro:IPR025668"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VU21"
                     /gene="sle_45410"
                     /gene_functions="other (smcogs) SMCOG1097:transposase
                     (Score: 102.6; E-value: 3.9e-31)"
                     /gene_kind="other"
                     /product="Transposase"
                     /protein_id="CQR63999.1"
                     /transl_table=11
                     /translation="MVLADKAYSSRAIRAHLHKRGIRAVIPVPAGQQAHRQRRGSQGGR
                     PPAFDRDAYKQRNAVERCINRLKQWRGIATRYEKTATIYLAGLHIAGIFFWSAR"
     gene            complement(25118..25417)
                     /gene="sle_45420"
     CDS             complement(25118..25417)
                     /codon_start=1
                     /db_xref="InterPro:IPR025161"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VW92"
                     /gene="sle_45420"
                     /gene_functions="other (smcogs) SMCOG1097:transposase
                     (Score: 82.6; E-value: 5.2e-25)"
                     /gene_kind="other"
                     /product="Transposase"
                     /protein_id="CQR64000.1"
                     /transl_table=11
                     /translation="MINAIAFKFQTGTQWVHLPEKYGNWRGVYNRLRMWAVDGTWERVF
                     TALIAQADAEEDLNWAVSVDSTIVRAHQHAAGARKKGPRSASPTTTPSAGPAAD"
     gene            25661..26623
                     /gene="sle_45430"
     CDS             25661..26623
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W4P6"
                     /db_xref="InterPro:IPR001584"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR012337"
                     /db_xref="InterPro:IPR024967"
                     /db_xref="InterPro:IPR036397"
                     /db_xref="InterPro:IPR038965"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W4P6"
                     /gene="sle_45430"
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 78.1; E-value: 1.1e-23)"
                     /gene_kind="other"
                     /product="Uncharacterized protein yagA"
                     /protein_id="CQR64001.1"
                     /transl_table=11
                     /translation="MSHRNAPLTPTGRLRLARCVVDEGWPLRRAAERFQVSHTTAARWA
                     GRYRQLGEAGMQDRSSRPHHSPRRTPATVEQQVLRLRREHRIGPVRLAARCGIAASTAH
                     RILVRHHLPALATLDRATGEPVRRYERSRPGELVYIDVKKLGRIPDGGGHKVLGRAAGS
                     PNKDRRNGAGYAYLHTALDDHSRLAYTEDLPDETAATCAGFLTRAVAWFAARGVTVERV
                     LTDNAWAYTKNTWRQTCHELGISPRWTRPWRPQTNGKVERFNRTLLDEWAYARPYRSET
                     ERREAFPQWLHSYNHHRGHTALKGQPPASRVPNLTGQYT"
     gene            complement(26620..27474)
                     /gene="sle_45440"
     CDS             complement(26620..27474)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W2D9"
                     /gene="sle_45440"
                     /product="Hypothetical Protein sle_45440"
                     /protein_id="CQR64002.1"
                     /transl_table=11
                     /translation="MHNTRCAGRQKRCTIRTCLRLSGSLHRTSTSSHGGEATGTGSREP
                     YPCPRRRHGSATTAPRRRPPPQAPVAQWIEQAPSKRLAAGSSPAGGASLRPPARSGGLF
                     AGQDVRGAKRRSPGRLSMTKDGLQGRTAVTGFSQVPVACVNVPDRKRSANARHLRLLEA
                     TRGFQSPLEIRQLPVDAPGIARRPVRPDDVRVPGRRQAAAVVHELEAVRPHRRHACRPS
                     RGGAARRSGCRENRRTAIGITVDHAVEQPEPRQATAEEATLLSTQKLVRQFGELMRAEL
                     QEG"
     gene            complement(27199..27271)
                     /gene="sle_45445"
     tRNA            complement(27199..27271)
                     /gene="sle_45445"
                     /product="tRNA-Arg"
     misc_feature    complement(27412..27414)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 catcgtctcc agccatctgc tcgccgaggt cgagcagtcc tgcacccacc tcgtcgtcat
       61 ggaccggggc cggctcgtcc aggcgggccc ggtcggcgag atcatcggct ccggcgacac
      121 gctcctgatc ggcaccggcg tgcccgtggc ggagccgctc gccgagaagg tcgccgccct
      181 gccgggcgtc gcctccgtcg tgcacaccga cgacgggctg ctgatccgcc tcggcgccga
      241 gggcaccgcc tccgccctgg tcgccgaact ggtccggttg gaggtgccgg tggagtcggt
      301 cggcccgcac cgccgcctgg aggacgcctt cctcaccctg atcggaggct ccgcatgagc
      361 ccgctgaccg agcccgccgc gcgccccggc ccgcccgcgg gcaccggccc cacggacggc
      421 acggcggccg cctcggggcc cctcgccgag gccgcccccg gttaccggcc gggccgcacc
      481 ctgccgctgc gggtcgagct ggtccgccaa ctggggcgcc gccgcacgct gatcatgggg
      541 gcgatcctcg cggccctccc cttcgtcctg ctggtcgcct tcgcgatcgg cggcgagccg
      601 gacgggcccg gcgaccgggt gacgctgatg gacacggcga ccgcgtccgg cgccaacttc
      661 gccgccgtca gcctcttcgt ctccgccggc ttcctcctgg tcatccccgt cgccctgttc
      721 tgcggcgaca ccgtcgcctc ggaggcgaac tggtcctccc tgcgctatct gctggccgcc
      781 ccggtgccgc gcgcccggct gctggtgtcc aagctcgccg tcgggctcgg cctcagcctg
      841 gccgcgatgg tgctgctgcc gctggtcgcg ctcgccgtcg gcacggtcgc ctacggctgg
      901 ggccccctgg agctccccac cggcggctcg ctcgacccgg ggacggcggc ggggcggctg
      961 gccgtggtcg tggcgtacct cttcgtctcc cagtgggtca ccgccgggct cgcgttctgg
     1021 ctgtcgacga ggaccgacgc cccgctcggc gcggtgggcg gcgcggtcgg cctgaccatc
     1081 gccggcaatg tgctggacgc cgtcaccgcc ctcggccact ggcgcgagtt cctgcccgcg
     1141 cactggcagt tcgcctgggc cgacgccgtc cagccgcgcc cggagtggtc cggcatgatc
     1201 cagggagcgg cgctctccct cacctacgcg ctggtgctgt tcgccctggc cttccgcggt
     1261 ttcgcccgca aggacgtggt gtcctgagcc cccgccccgc ccacgccccc cccgctaggg
     1321 cctctcgttt ggatcatgcc gggctcgcgg ggcctggcac cccgcctcgc cgcgttgtcg
     1381 tcggttgcca tggctccgcc atggcgccct cctccgcctt gcgatgcacg gcaccagacc
     1441 ccgctccctg atccggcctg atccaaacga aagaccctag cgccgcgacc gccgttacct
     1501 cccacgaccg cgtgaccgcg gtgaccaccg tgcccggaga gcccgtcccc ggcgccccat
     1561 tgacctttcc ttacgcatga gtaagtttac tttggagtaa gtaggtacgg cagcacgtca
     1621 gtccccccgc gaccgggagc cgtcatgggc gtacgcaagg agctgaaacg ggcgaggcag
     1681 cgcggcgacc tggccgcccg gtcccgcccc gagatcgtcc gggacggcgg cggcaccgtg
     1741 cgcgaggtcc gcaccgcccc cctcgcgccc cgcccccgca ccggcagcac ggccgacatc
     1801 cccttcacca acgccgccga ggaccccggt gccgtggtcc tgcgccggga gcgcgccggc
     1861 acctggcagc cggtgaccgc cgccgagttc gcccgcgaag tgaccgccgt cgccaagggg
     1921 ctgatcgccg ccggtctcga accgggcggc cgggtcgccg tgatgtcccg cacccgctac
     1981 gagtggacgc tcctggactt cgcgatctgg gccgccggcg ggcagaccgt ccccgtctac
     2041 cccacctcct ccgccgagca ggtggagtgg atcgtccgcg actccggtgc cggccacgtg
     2101 gtcaccgaga ccgccgagca caccgccacc gtcctgaccg gcacggccgg ccaccccggc
     2161 ccgccgcgca cctggcagct cgacgcgggc gcgatcgccg acctcaccgc cctcggccgg
     2221 ggcctgcccg acgaggaggt caccaagcgc cgtaccgcgc tgacccccga caccgtggcc
     2281 accatctgct acacctcggg caccaccggc cgccccaagg gctgtgtgct gacccacgcc
     2341 aacctgcacg ccgaggccgc caacaccgtc gagctgctcc accccgtctt caaggcggtc
     2401 accggccgga cggcctccac cctcctcttc ctccccctcg cccacatcct cggccgcacc
     2461 ctccagatcg cctgcctggc ggcccggatc gagctgggcc actgcccgag catcaagccc
     2521 gccgaactcc gcccggcgct gaagtcgttc cgcccgtcct tcctcgtcgg cgtcccctac
     2581 ctcttcgaga agatccacga caccggccgc gccaccgccg agaagctggg ccgcggcgcc
     2641 tccttcgacc gcgcgcaccg cgtcgccgtc cgcttcggcg aggcgcacct ggccaggttc
     2701 ctcggcaccg gcaagggccc cggccccggt ctgtacgccg cctgggccct gtacgacctg
     2761 ctggtctacc gccgcgtccg caaggagctc ggcggccgga cgcgttacgc catcagcggc
     2821 ggctccccgc tcgaccgcga cctgaacctg ttcttctacg ccgccgggat cgtcgtctac
     2881 gaggggtacg ggctgaccga gaccaccgcc gccgccaccc tcgtcccgcc cctcgcgcca
     2941 cgccccggta cggtcggcct cccggtcccc ggcacggcgg tgcgcatcgc ggacgacggc
     3001 gaggtgcaca tcaagggcgg catcgtcttc ggttcctacc ggaacgaccc cgaggccacg
     3061 gacgcggtcc tcgacgacgg ctggttcgcc accggcgacc tgggctccct cgacgaggac
     3121 ggctacctca ccatcaccgg ccgcaagaag gacctcctcg tcacctccgg cggcaagaac
     3181 gtctccccgg ccgtcctgga ggaccgcctg cgcagccgcc cgccggtcgc ccagtgcgtc
     3241 gtcgtcggcg acaaccgccc cttcgtcgcc gccctgatca ccctcgaccc ggaggccgtc
     3301 gcccactggc tggccgtccg caagctgccg gccggcaccc cgatgtccga ggtgatccgg
     3361 gacccgcgga tgcgcgccga tgtccagaag gccgtcgacc acgccaacga ggccgtctcc
     3421 cgcgccgagt cgatccgcgc cttcgccctg gtcgagggcg aattcacgga ggagaacggg
     3481 ctgctgaccc cgtcgctgaa ggtcaagcgc caggcggtgg cgacggcgta cgccgcggag
     3541 atagaagcgc tctacgcgcc cggccgctga cacccggacg ctcccgcgct ctgggacatt
     3601 cgagtgaaat ctactgtgtc gtcccttcgg tgaggtttct tcagaggcct gcttctcgtt
     3661 ggcagcctgc gggtcatggt gcgagccgtc catgtcgtgc tcgcgcggtt ccgtccgtcg
     3721 tctcaggcat gaccgcagag aaggggaagt ccatgaagag gagcgccgca gtcgtcacgg
     3781 gcacggtcgt cgccctgggc ggctctgccg ccccggcctt cgccgacgcg gtggccgagg
     3841 gcgccgccac cggttcgtca ggtggcctga ccggccaagt cgtgcaggtc ccggtacaca
     3901 ttccgatcaa tgtgtgcggt aacaccgtga acggcgtcgg cctcctgaat ccggcgtacg
     3961 gcaacaagtg caccaacgac tgaggtcgtc ccgcaccagc ctcccggctg cgccacggcc
     4021 ggcctcggcc cccgtacgcg gaccagggca ggctttccca tcaccaccag caggaagaca
     4081 acgagagtgc gacagaccct gagcagggga gtgttcgccg tcgctgcgac gagcgttctg
     4141 tccctgtgcg gcagttccgc ccttgccgac acgcaggcgg atggcagtgc catgaatgtg
     4201 ccgggcgcct cgtccggcaa caccgtccag gccccggacc acgcgccggc ggacccgtgc
     4261 ggcgacacgg cccacgcgac cgacgtgctg gacacggtgt tcggcgacgc gtgcgccgac
     4321 gagccggagg aaacctccgc cgaccacgac ccggagcccg agcgggaccc ggacagtcac
     4381 gactccggac ccggcgacgt ggtgtccgaa ctcctcgggc aggcccaggc cgtggcctcg
     4441 gccgacgaag gctcgcgcag caccgtgcag atcaccgacg aggagtcggg gctgttctgc
     4501 ggcgccctgg ccgacgcgat gagcacgctg agcctggtca cctgtgccga cgaggacggc
     4561 ggttacggcg acgacggtta cggcgacggc ggttacggcg acggggcgac gccccccgtg
     4621 gaccacacgc cgaaggagac cccgccgccc gccgacgaca aggtgacgcc gccggcggag
     4681 gtgaagcccc cggcggccga cgtggagccg cccgccgacg acgaggaccc gccgtcgctg
     4741 gccgagacgg gcgccggtgc gctcctgtcc accgcggccg tgagcaccgt gcttctcgcc
     4801 ggcggagcgg tgctgtaccg ccgcgggcgg cgcacgatgc cgcgccagta gaacggctcc
     4861 gcaccggccc ggtaccgccg cggccggtgc accgccccgc cggtcctgac ggcaccggca
     4921 ccacccccag ggggcgcatg ccggaacggc cttcacgacc cgtcgtggtc gtgaaggccg
     4981 tcgtcgttcc cgcgcctccc tcatgcctcc ccgcgattcc cttcaccggg gcgtcggcgg
     5041 cgcgggcacg caccgccgcc gacgccccgc ccgcgcatca cggcgccccg ggggacaggg
     5101 tgtcgctcag cgactgcccg tcagatcggc cggttcggcc ggttcgaccg gctccgcctg
     5161 cccgggcacg gagggcgccc tgaccgcccg cggcaccacg ccgccctccg ccgggcaggc
     5221 cgccgcctcc gggtgctccc cgcgccgtga ccgccgtacc agccgccccg ccgcatgacg
     5281 gccccacagg gcccacagcg cccggccggg cgcccggtcg tcccgcgcgt gccaggccag
     5341 ttcgcgcccc ccgggcgccg ggcgcaggac ggtcagcggc gcgtagttct ccaccacgaa
     5401 cacccgcccc ggcagcggcg cgccctccgg cagcggccgg tgcgtcagat ccaggtggag
     5461 ggcgcgtacg acgtccaggc cggagccgtc ggcgaacagc cggaactggg cgcccggacg
     5521 cggattgaaa tccagcaggt gatagcgccc cgtcgagccg cagcggcgga agtccaggtc
     5581 gaagatgccc cggtagccca gcgctccggt gatccgctcg gtgagcgcct gcacctcggc
     5641 gttgggcgtc cagcacccgg ccgccgtcag acccgcgccg cgcggccggg cacgggtctt
     5701 gcggccgcaa ccgcccgcgc gcaccgcacc ggtgcggtcg gcgtacccgt gggcgaacca
     5761 gtcacggtcc gcacccggcg gcaggaacgc ctgcagcagc agccggcagc ccgcctcgcc
     5821 ggaccgcagg tacaactccc gtgcctgctg cgccgagcgc accagcacgg tgctgcgcag
     5881 cccgctgtcc gcgggcagca gccagggccg gctccacttc gccaccagcg gcagtccgag
     5941 ccggcaggcg gccgaggcgg cctccgccgg gctgtccggc accaccgtca ccgggtgcgg
     6001 gacgtccagg gccgcgcaga gaccggccag ttccgccttg tcggcgacgc gcccgggcag
     6061 cgtgcccggc gccgcgggca gcagataggc gggcgccagt tccgcgcgca tccgggccac
     6121 ggcgatggcg ctcgcgtcgt ccatcgtgac caggacggcg ggacgcgcga tccgggcggc
     6181 gacccggcgc agcacgtccg cgatctcggc cggggacgcc ccgggcgggg gcggtgtgtg
     6241 cacccgccgt acgaaacggg aggcccccac gggacttttc gcgcagtcgg cgaccacgtg
     6301 caccgccact cccgcccggc cgagcgagcg cacggcaccc agcgttccgt ggtgaaaggg
     6361 attccggtcg atccgcagca gtacggcggg aacgccggtg tcgaacagcg acacgggatt
     6421 tcttctttcg ggtcggacgg gtgccggttc accggtgcgg gcgaccggga cacccgaaag
     6481 ccgtagcggc ggtggcgtga ttgtctttca tatgactgag tgtcagtgag gaacaggaga
     6541 gaggtttccg gtgggcggcg gcagacgtcg gaatccgccg gtgggagaag tcgaattcgg
     6601 cagtacgaga acgggaagag gagccgcatg tccccacagc agccacgggc gcggtccggc
     6661 cggctggcgt tcgtcgcggc gtcggtcgcg gcgtcggccg tgctggccgc gggcccggga
     6721 ttcgcggcgg gcgcgggccc ggcccgggcc gccgcgccgc tcgccccggc cgtggccggg
     6781 cccgcggcgg acccggtccc cgggacgccc gccatccctg cggcaccacc ggttccgcag
     6841 ctcacccagg ccccaccggc cgcgaacgag ccgaaggacc ccaaggaccc gagagacccc
     6901 aaggacccca aggacccgag agacccgaag gacccgaagg accccaggga ccccagggac
     6961 cccagggacc ccggagaccc gaaggacccg aaggacccga aggaccccaa ggacccgaga
     7021 gagcggaccc ccgccttcgg cgcctacctc cactacggct cgcccggtgt gacccggatg
     7081 gacgagctca gccgctggct gggcggggcc gagctgcgcg tcggccacac ctacctcccg
     7141 ggcgaccgtt ggagcaacat cgcgggcgcc cccggcttcc tcgacgagtg ggcccggtgg
     7201 cggaacggga agcccgaccg gatcttcgtc ctcaacgtgc cgatgctgga gcgcaacgag
     7261 gagggcgtcc cggacgacga ggtgcgccgg ctgctgcgcg cgggcgccgc cggccggttc
     7321 gatcaccact tccgggctct cggcgagcgg ctggtccggc tgaacgcgcc cgacacggtg
     7381 atcgtgctcg gctgggagat gaacggcatc acgtacaccc atcgctgcgg gccggacccg
     7441 gcggcctgga agacgtactg gaacaggatc gtcaccacca tgcgttcggt gccgggccag
     7501 aaattccggt tcgacttcgc gccgagccgc ggccgggacg ccattccgtg gacggagtgc
     7561 tatccgggga acgacaccgt cgacatcatc ggcatggacg cgtacgacca gccgcgcggc
     7621 atgtccttcg acgaacaggt ggcggagccc tacggactcc gggcgcacgt cgaattcgcg
     7681 aaagcccacg gcaagcccat ttcctatcct gaatggggcc tctttcgcaa cggtgacaac
     7741 gccgcatacg tgcagggaat gctcgcatgg atggacgagc accaagccct ttaccacacg
     7801 ctgacggatt actgcccgca cggtgtgtgg cagtgcgacc ggaatccccg gtccgccgcg
     7861 gcctaccggg ccgtcctctc cgcccgcacc ggcgaccccg gcgcgccgcc ggccccggtc
     7921 cccgcccccg ctccgctccc cgtccccacg ccggccccgg ctccgcagcc gagccggccc
     7981 gcgaccggct gctcgtcgct gagcctgggc ggctgggtcg agcgctggct ggtcggcgcg
     8041 ctctgcacgc gtctggaccg gtggtcgcgc gacgggtgac cccccgggcg gcggcgggcc
     8101 tcgtcacggc ccgccgccgc ccccgcgctc ccgccaccgc cgcagcgcca ccttgccccg
     8161 ccgccgcgcc gcgtccccgc cggccgccgc cgccagcagc ggtgccgtgc gccgccgggc
     8221 cagcagcagc cgctggttca ccaccggctc cggacgccag tggtgcttgt acggctcgtt
     8281 gccgcgcagc aggctcagcg tgccgcccgc ccgctccccg cccgtgacgt gcctgccgca
     8341 ggcgtccagc agcatcaccg ccacgtccgc cctgcactcc cgcagccggg gatgggcgcc
     8401 gtagagatag ccgcccgcga gcgccggtga ccgcagggtg acgtccacgg ccaccacctc
     8461 gtcggccatc cggaactcgg tgaccaccgc gtcccccgag cggaccatcg gccccacggc
     8521 ccgcaccaga tgctcgcgga agcgcggctt cagatgctcg cccgtcacct tgcgcccctg
     8581 ccactgcaac cggtgcagct ccagcagccg ccccagggcc gcgtccacct cctccggcag
     8641 gacggcgcgg ctcttcaccc cgagggcgtc cagcttgcgc agcttggcgc ggacccgctg
     8701 ctgcgccttc gccgacggca gccgggcgac cagctcggcc atcggcacgg cgggcagctc
     8761 caggcacagc gagtcgccca gccggcgccg cggcccgcgc cagcggtcgt ggacgcgctc
     8821 ggccgcgccg ccgggccgga cctcgcgcag gtcgaccagg gcggtgcggg cggcggcgta
     8881 cagggcctcg gtgagcgcgg ccacggccgc gtccccgtgc tcgtcgtcca ccagcacgtc
     8941 cccgtagtcg gagagacacc cgccgagcgg caccagcgcc gggagcgggc gccgcacccg
     9001 catcagcggc gccgcggcgg ccagttcgcc gccctcccgg accagcacca gccgcagccg
     9061 gccgcgacgg ccgtacgaca gccaccacga gtgcagccag gcgtggctct ggaacggggt
     9121 cgccgtcgcg caccgccggt acagccggga ccactcgggc gccagcgcgg cgaaggcacg
     9181 ctcgccggtg accagttcgg tggtgtacgc cgggtacctc acgactgccc gcgcacgtcg
     9241 gcggcggtgg cgggcgccgg tacggcggcg gcccggccgg agccggcggc ggcccggcgc
     9301 ggccgcacca gcagcgcgag tccgccgagc aggccgcccg cgctcgcgcc gaccagaccg
     9361 gccaggccgg ccggggccga ggacggctcg gtgggccggg tggcgcgcgc gaacgagcgg
     9421 agggtgacat gggtggagcc ggaggcgttg cccgcgtgcc gggtcagcgc ctcggagacg
     9481 gcgttggcca tgtcggcggc cagatcgggc cggtgggagg tggcgctgac cgcgaccatc
     9541 ggcgcgtccg gcgaggtcgc cgtccgtacg ctccgcttca gcgtcgcggc cggtacgccc
     9601 gcccccacct gggcgtcggc gagcaccgcc acctgtgtgg cgacccggcc gtaagcctgt
     9661 gcgaagccca gggcggacgc cgggtcggcg tcccgcgccg ggacggcgac gacgtaactc
     9721 gtcgccgtgt agtccggcgt cctgaccagg ccgtagccgc cgccgagcag gccgccggcg
     9781 agggcgccgg cggccaggac cgaccagggc ggcagggtcc gggcgcgggc ccggacggtg
     9841 gcgcgggtgc ggccggcggc ggatgcggcg ggcagggccg ggcgcgcggt gccggttccg
     9901 atggcgccgg ccgcccggac gccgcgggtc cgggtcccgg acctgttctc gttccagttc
     9961 tcggtcacgt cgtcggtcac gtcgtcggtc acgttctcgg tcatgcggag ctgactccct
    10021 ggggtgccgg ggacaacgag tgccgcgcca gggcggtggc gtagacgtcc atcagccggg
    10081 cggcgctgcg ggtgatgcag tagtggcggg cggccttcgg tgccgtgcgc gggccgggac
    10141 ccgccgcgcg gacctcggcc agcgcgcggc cgaactcctc ggcgccgccg gggacgcgcc
    10201 gggcggcggg cgcggtgtgc gggggcaggt cctccagcgc cgggcaggcg gcgtacagca
    10261 ccggcagccc cgaggccagg ccctccaccg cggccagtcc gaacgcctcc tcgggggacg
    10321 gcgaggcgag cacgtccatc gcgcaggcca gcgacggcag gtcggggccc ggggagccgt
    10381 cggggaggcc ggggcgttcc ccggtgagca gcacccggtc ggcgaccccg gcctcgcggg
    10441 cctcgcgccg cagcacgtgt tcgtccgggc cgccgccgac cagcagcagc cggcagtcgc
    10501 cgggcagccg ggccagggcg cggacgagga cgtcgaaccg cttgccgggg gtgagccggc
    10561 cgatgccgcc cacgacgaac gcgtcgtcgg gcagccccag ccggcgccgg gtgcggtgcc
    10621 gccggaccgg gtcgaagcgg aagcgggcca ggtcgatgcc gttggggacg acctcgatcc
    10681 gggaggcggg cacgccccag cgccgcagcc gggcggcgac ggtcggggag acggcgaccg
    10741 tggtggagcc cagccgctct ccggtcagat acagggcgcg cacccccgcg gtcagcgggc
    10801 ggccctccat ctgggtctcg cccagggagt gctcggtggc gacgaccgcg cggacgcccg
    10861 ccaggcgcgc ggcgaggcgg ccgtagaggc aggcccggta gaggtgggtg tgcacgaggt
    10921 cgtagccgcc ggcgcggacg agaccggtca ggcgcggcag cgcggacagg tcgcggttgc
    10981 cggtcatgcc gaggtggacg accggcaccc cgtcggcacg gaggccgtcg gcgaccgggc
    11041 ccgggttggt gagcgtcacc acctcgcacc gcgcgggaag gtgccgcagc agcagtcgta
    11101 gctgctgctc ggcgccgccg acgccgaggc ccgtgatgac gtgcaggacc ttcacgcgga
    11161 ccccacctca gatcccctcc gccgcgcgtc ggcgcagccg gtgcagccgc gtcttcagca
    11221 gcagccgcac ggcggtgtcc cgctgcccga cgtgcacccg cggcagggcg tacggtccgg
    11281 tcagcgggcc cgggtcgatg gcgcagccgt aggtgtaccc ggcgtcccgt acggcgtcgg
    11341 cggcccgccg gtcgaccgtg ccgtacgggt agcagaaacc ggcgaccggg gtgccggtca
    11401 gctcggtgag cagcgccctg ctccgagcga cctcggcgcg cagggtggcg tcgtccgccc
    11461 gcgtcaggtc cacgtgggtc agtccgtgcg acccgatctc cacgccctcg gcggcggccc
    11521 gccggatgcc gtcggcggtc agcagcggct tgcgcgggcc cagcgggtcc caggcgttga
    11581 cgccgccgag gcggcccggc aggacgaaca gggtggcccc gcacccccgg cgccgcagca
    11641 ccggcagcgc gtgctcgacg aagtcggcgt agccgtcgtc gaaggtcagt ccgaccaggt
    11701 cccggccctc gccccgggcg cgcgcggcga gcagctcgcc cagggacacc ccgcgcagcc
    11761 cgcgccgccg cagccagccg agctgcgcgt ccaggcggcc gggcgtgacc gtgatccggt
    11821 acgggtcgtc ggagcagtcg ccgacggagt ggtacatcgc cacccagggc acggggccgg
    11881 ggcggcgccc cgcgcggctg ccggaccggg gacgcgggag ggcggcggcg cggctcgcgg
    11941 ggcccgcgga ggccgccgcg ctcgcggcgc ccgcgcggtc agcggaaccg gtggaaccgg
    12001 aggaaccgga gggaccggag cagcccgcgg aaccgcagga accgcaggaa gtgcaggaat
    12061 cgctgggacc ggtggaaccg ctggagccgg tgggatcgag ggaagcagtc atgcggatgc
    12121 cttcgggaga cgacggaacg gaggaaaccg gcagcgggcg cgatgccctg gacgcccagg
    12181 acccggccga gcagggcgaa gacggccgtg acggtcacgg cacctacgag gaggccgagg
    12241 gcgggcggcc cgcaccggcc cgcggccagc gcgcccgccg cggtggcgcc cgctgccgcc
    12301 cccgccggcc cgcccagccc ggccaggacg cgccgcacgc ggatggggac gctccgctcg
    12361 cccatcccgg cgagcagcag cgcggcggtc acggtgatgc cggccgcgtt ggccgcggcg
    12421 atgcccgtcg cgccccaggg cccggcggcg cacgcgccga tggcggcggt ggccgcgacg
    12481 ccgagggcca tcgcgccgag cgggtaccaa ctggcccggc ccgccgagaa gtacgagcgg
    12541 gccagcgcgc ccaccacggt ctggccgagc agccccaggg cgtacacgcg catgacgccc
    12601 gccgtcgccg cggtgtcccc ggcggtgaac gcgccccgct ggaagagcac ctcgacgatc
    12661 tgcggggcgc aggccacgac cgtggccgcg cccagcagga ccacgcacgc ggccagcgcc
    12721 acgtcccgct ccacccgggc gcgggcccgc gcggtgtcgc cctcggccag ggcccgcgcc
    12781 accaccggga aggtgaccgt gcacagcatc agcgacagcg tcatcgggat ctgggcgacc
    12841 ttctgcgcgt agttgaggtg cgagatggca ccggcgggca gcccggcggc gaggaaccgt
    12901 tcgatgagca cctgggactg gcggcacagc gcgaagagca gcacggtggc gaacagggcg
    12961 agggcaggcg ggcacgtccc gtcgtccgtc gccgcctccg gccgcccggc gtcgtcccgc
    13021 cgccgtagct gacgcagcag cgacggaagc tgggccgcca ccatcaggca gccgcccgcc
    13081 gcgacgccca ccgccgccga ccgcacgccc agccggtcgc cgagcacgac catcgcggtg
    13141 atgatgccgg tgttgtaggc gacgtagatg gccgccggcg ccaggaaccg gcggtgggcc
    13201 cgcagggcgg cggagcagta cccggccagg ccgaagctca gcacacaggt cgcggtgagc
    13261 cgggtgcact ccacggcgag gtcgtggccg ggcagtcccg gggcgagggc ccggaccagt
    13321 tggggcgcga ggacgacggc cagcgcggcg accgtggaga aggcgagcgc cagccggggc
    13381 agggtggtgg tgaccagggc gcggaccggg tcgcccgggg cgccccgggc gcggcgggcc
    13441 agggccaggc tgaacatcgg gatcagcgcg aaggccagcc cgtcctcgat cagcagcgtg
    13501 gcggcgaact cgggcaccgt ccacgccacc aggaacgcgt ccgtctcgct ccccgccccg
    13561 aacagccggg ccagcgcctg gtcccgggcg agaccgagga cggacgcggc gacggacagg
    13621 gcggcggtga gcagggccgc gcgggcgagg aagcgcgggg agccggcggc ccgttcgccg
    13681 ccggcggcgt ccggcgcggt gggggtccgg ggggccggca ccgccgccgc gtcgccggcc
    13741 cggggaggcg tcaccgtcat cgcgccggtg cctcctgcgg cccggccccg gcggcccggg
    13801 acggggcccg cccgccggta ccgcccgccg cggccccctc ccggcagtcc ccggccgccc
    13861 ccgcccccgc cgtggccctg tgccctccgc ggccgcccgc gccgggtccc gtcgccaggc
    13921 tccccccgcc accggtaccg ggtccggtcg cggcactcgt cccgccgtcc gtgaccggtc
    13981 ccgcggcgtc cccgtcctcg ccgccgccga ccgcccacca ggcggccagc ccgaggctca
    14041 ccgcggtcag cacggtcgac gggccgccga tgtcggcgta ggcgaagtcg gtgagctgcc
    14101 acaccagcag cccgcacgcg accagcccgc agtcccgcgc ggcggcgccg cggcatctga
    14161 cctcgcgcac cccgcgcacc agcagcgcga gccagctccc ggcgaacgcg agcagtccgg
    14221 tcaggccctg ttcggcgagg atgagcaggt acatgttgtg cggcgagagc agcggctgcc
    14281 tgcggaaggc cgcgcccgcg ccctcggtgt cgctgcccga ggacagcgcg agggaggcgt
    14341 gcgcgtcccg gtgttcggga aagcccttga gcccgacgcc ggtcagcggc cgctcgcgcc
    14401 acatgccgcc ggccgccgcc cacatggcgt accggtcggt gaccgactgg tcgggggcgt
    14461 cggcgacccg ggtgatgctg tccaggcgct cctggagcat cgccgtgccg agccccagcc
    14521 cgcccaccag gacgaccgcg caggcggcca cggccgcccc caccgccagc gcccgccgca
    14581 ccccggccag cagcagttgc accacgcacg ccaccgccgt ggcgatccac gccccccggc
    14641 tgaaggagac cgcgagcggc gccagcagcg ccaccgcgca tccggcggcc acgacccgct
    14701 gccgcaccgg cgcgtggccc agcgcgagac cgagcgccgc caccagcccc agggagacga
    14761 ccgtcgccat ccccatcacg tcctgcggac cgaaggtgcc caccgcccgg accggctccc
    14821 cctggtacga ggcgccggtc gcggtggcgt actggtgcac gccgaccgcc ccctgccaca
    14881 gcgccagccc caccagcgac caggccagca gccgtacgtc gcgccgctcg cgcaccagca
    14941 gggcgacggc cgccgggagc agcacgaaga cctggaggta gcggaccagc ccggtcagcc
    15001 cggcggcggg ggacggcgcg tgcagggcgg ccagggcgat cccggccacg ggcagggcga
    15061 gcaccacggc cgccgcaggg gtaagggggc gccgccggtc ccgcgccagc cgggccgcgc
    15121 agtacaccac gaccagcgcg gaggccgcgt cggcgggatg cggcccgccc gccccgcccg
    15181 gcgcgaactc caccgcgagc agggcgacca cggcgaccac ggccaggacg ggcggcagcg
    15241 cccgcgcgcc gggcccgggg ggacaccggt gcgcgggccg gtgcgggggc agcgcgtggc
    15301 tcaccgcggt cagctcccgg tggggcgcac gagcgtgacg gccgtgcgca gcaggatgca
    15361 cacgtcctgc cacagcgacc agttgtcgat gtaggcgttg tcgaagcggg cccggtcctc
    15421 gatggaggtg tcaccgcgca gcccgtggat ctgggcgagc ccggtgatgc cggccggcat
    15481 ccggtgccgg gccgcgtaac cgggataggt ctcgctgaac ttggtgacga agtaggggcg
    15541 ttcgggccgc ggcccgacca ggctcatgtc gccgcggaac acgttccaca actggagcag
    15601 ctcgtccagc gaggtgcggc gcaggaagcg gcagaaccac ggcatccgcc gctcgtccgc
    15661 cacactccac cgggtcgccg actcgtgctc gtccaccggc cggtgggtgc ggaacttcag
    15721 cagcgtgaac ggtttcccgt cctggccgac gcgcacctgc cggaacacca cccccggccc
    15781 ctcgctgacc cgcagcacca ccgcgcacgc cagcagcagc ggaccggccg ccagcagcag
    15841 caccccggac accaccacgt ccagcacccg cttgcccagg gcgccgcccg gccgccccgc
    15901 ccccgcctcc agccgccggc gggagaaccc ggcgatctcg tcgcggctcc ccgacgacgg
    15961 ggaccgcggg tcgacctccc agaccgcgca gccggacgcg gcgagcgccc gcagcagcgg
    16021 cgcctgccgc gtccgtaccg agggatgcac caccagcacc tcccgcaccc cgttccgggc
    16081 gaccgcccgc cggacctcct cctccgtgcc cagcacgggc agccccgccg cgcccgtccc
    16141 gggcccgccg agcagggagg acccgaacgg cccgccggtc accacaccca ccgggcgcac
    16201 cccgcagcgc gggtggcgca gcaccgccgc ggccacgcgc tgcgccaccc cggccggccc
    16261 gatgacgagc gcggcgcgcg gccggttgcg cagcgtcgta cggcgccgcc agtgcaccgc
    16321 gccgcggccc gcgcagcccg ccgccgcctg cacggtgaaa ccgagcagca ggctgtcggc
    16381 ggacagcgcc tggtgcgggg tgtacgccgc cagcagcgcg gccagcgcga gccaggcgac
    16441 ggcgatccgg ccgcacacgg agggcagttc gtccaggaca ccggccggta cggggggaag
    16501 cccacgcggg cgcagcagca gcgtcgccgc caccagcggg gccgcgagga gcgggcggtc
    16561 cggggcaccg gtgagcgtca gggagcccag cagggccgcg gtgccgtccg cggcgagcag
    16621 cggcagccgg gaggccgggc gcgccgcggg gcgccgggcg ggaagcgcga acccgccccc
    16681 ccgcgtgcgc ggcggcagga tccggagggg ggagagggcc aggtcccgcg gttgccctgc
    16741 gggggagggg acggtgcttt ccgcggtcac gactggatgg actccctgta ctcggtgggg
    16801 acgacggccg gacccgctgc gtccggcccg ccgccgagga gttcgccgta cacggcggcc
    16861 acggcccggg ccgtgcgccg aacgtcgtgg gcggacagga catgggcccg cccctggcga
    16921 gccgtcgagg cgcgcagtgc cgggtcgagc agcagcgcgc tgacggcgcc cgccagcgcc
    16981 gcggggtccg tgggcggcac gaggcagtgc ggcgcgagcg cgggcggcag gacctcccgg
    17041 gcgccgtcca cgtcggtcag caccacgggc cgcccgcagg ccatggcctc cagcggggcc
    17101 agcgctatgc cctcccagcg cgagggcagt acgaccacgt cggcggcccg gtaccagggg
    17161 gcggcgtcgg cgacggcccc cgtgaaccgc acggacgccg gggccagcgc ccgcagccgc
    17221 gcccgctccg gcccgtcccc gaccagcacc agccgggcgt ccgggacccg ctcggcgatc
    17281 cggtcccagg cggcgatcag gacgtcctgc cccttctgcc ggcacagccg ccccacgcag
    17341 accacgagcc gggcccgcgg accgaggtcc gcgagcagcg gcggccgtac ggcggggccg
    17401 ggccggaaat ggtccgggtc gacaccgttc ggcaccaccg cccaccgccc gcggatcccc
    17461 gccgacaccc cccggcggcg ctccgcctcg ctgacgcaca ccacccgcgc ggcccatcgc
    17521 gccgcccacc gctcccagcc gagcgccagg acggcgggga ccccgccgac cgcctcgaac
    17581 gaccacgcgt gcggctggaa cacggtcggg atccgcgccc ggacggcgag ccgccccgcc
    17641 agacccgcct tcgcgctgtg cgcgtgcacc agatcgggcc gtacgtcctc gacgatccgc
    17701 gcgagccgcc atgtctcggc ggggagcgac ggccccggcg agcgcgtcgc gggccacggc
    17761 cgcacctccg cgcccagcga acgcagcgac gcggcgaggg gaccgtcggg gcaggcgacc
    17821 gtgatgtccc acccggcggc gagctgtgcc cgtgccaggt ccgtcacgat ccgggcgacc
    17881 ccgccgtcca cgggctgggt gaggtgcagg acccgcggcg caggtccggt cgctggcagg
    17941 tgcatgcgcg cttcctcgct cacggatggt gctcgggacg ggcgggaacg cgccgcggag
    18001 ggccgcccga atgtgatgcg ccggcaccgg ggcgccggca tcggaggtgc gtcggacggt
    18061 gtgtcaccct agccgcaaga cgtagctaat actgcgaaac cggataagtg tgtcggatcg
    18121 ggtgacaaag cgggccgggt tgcatgttcg tcacccggtt ggtggcgcaa ccggtggggg
    18181 gaccatgcgt tgacactgcg ccgggcgttc gcccggatgg tcgtcaaccc caaggagcac
    18241 ctctccatgt cgcgtatcgc gaaaggcctg gtcctgacct ctgtcgccgc cggagcggtg
    18301 acgggcacca cgggcgtcgc cgtcgccgcc gacgccggcg cgggcgccgg tgcgaaggcg
    18361 accgccgcgg actccccggg gggactggcc ggcagtgccg tgcaggtccc cgtgtacgtc
    18421 ccggtgaacg tctgcggcaa cacggtcgac gtcggcggcc tgctgaaccc ggccttcggc
    18481 aacaagtgca agaacgcctg aggccctttc cccttctcct gccgtccgtc cggcccgcgg
    18541 ctcgtccgtg gcggcggcga ccggcggccg tgtgcgcgag accgcccggc gttcgcccgt
    18601 tgccccgaat gggggtggtg cgaacggccc ggcgcgctgg ccccgtcacc cggtctgagc
    18661 aggtgcggac ggctcgcggc gacggccgga cggcaacgct gggcaaggga tcggttgcag
    18721 agcgcgaggg cggcttccac ggtggcagta cgaccctgca caccaccgaa aggaaccctc
    18781 atgcgtctgc ccgcacggcg tatcgccgcc tccgcgttct gcgccaccct cctgctcgcg
    18841 gtcaccgggc cggcggcgac ggcggccgac ggcgactcgg tccgggagcg gaccagcgcg
    18901 gcgtcccggg cgccgctgcc cgacgtcggc gcgctcaccg cccaggtcca gtcgctcagc
    18961 ggtctgggcg gcgtggtcgc gccggtcagc gatctgctcg gcgcggtgct caaggccgac
    19021 gacggccgcc tcaccaagga gcaggcggag cagttctcca aggccgtgga ggacgccctc
    19081 gccaaggcac aggcgacggg gatgccgatc gcaccggagg cggcggcgcc gggcaccacc
    19141 acgccggaca ccgccacgcc cggcaccacg gcccccggcg tcggcacgcc ggcccagccg
    19201 ccggtggcgc tccagccgcc cgccgtcgcc cagccgaacg acgacgcgcc ggccaccacg
    19261 ctgccggccc cgctcgcccc cgccccgctc gcccctgctc cgctcgcccc ggccccggct
    19321 gcgcccgccg cggtcgcccc cgccgcggac gagtccggca cggcgtcgac cggtctcatc
    19381 ggtgcggcgc tggacgcgct gcggaagtcg atcgaaaccc tgatcggggc cagtacgtcg
    19441 gcccagcccg agcaggtgag cccggcggcc gccggcgtcg tgaccgacgt cgtcaacgtg
    19501 gtcgcggcca ccctgttcgg cggcgggctg cccgcccccg acctggccgg cctgcccccg
    19561 ctgcccgccg ccccgaacgg cacgacgccg gcgaacaccc cggcggacac cccggtgaac
    19621 gcaccggcga ccccctgacg gtcccgcccc accgggccgc cgcacccgcc ttccgggcgg
    19681 gtgcggcggc cttttcgcgt ctcgcccccg ttccggcgcg cacaggaccc ggtacgcatt
    19741 ctcatccgat ttccgttacg ggtcctgata tgaggatgag aaacacgggt gagacacacc
    19801 gttcgttcgg gtgggtcacg gaaaggtcgc ggcactcggg gtttccggtc cgggcggcac
    19861 tcgttaggca cggcaccacc cctttccgct tttgcgcggt gagggattcg ccgaagaaag
    19921 gaagacgatg aagcccctga aggccgccgc cgcagttgcc ggatccctgg ccctggccgg
    19981 agccgccggg cccgcgtacg cccacaacga cgtcgccgaa ctcacgcacg ccgtcgacca
    20041 cgtcgcgggc gtggtcaccg aggagccggt gatcggcctg ccggtggagt ccaagcccgg
    20101 ggagtcccgc accgaggaca agtcgtccgc cctgcgcacc gtgaagaccc tgatcgacga
    20161 ggtgggctcc gtgggcgccc tgctcggcgg cctgccggcg cggggctgaa ccccgttcgc
    20221 catcaccgac ggacggacac cggacgagga gcacgatcat ggccgtcagc gagcgcgagg
    20281 cagcccggga cgcggggcgg gaaccggcgg acccggccgg aggcggcccc gccgacgcca
    20341 cccgccgccg gctggcgcgc cggctgctcg tccccgccct ggccgcggcg ttcgtccccg
    20401 tggccgccgc ccccgggtcc ccccggcccg cgaaatccgc gggggattcg aaagccgcac
    20461 ggacggaccg gcgcggcacg gccggccgcg cgcggacagc gacccgcccc ctggccgccc
    20521 cggacgacgg cgcgttcgac gagacctacc tcggccggcg catccgcggc gtcaggacgc
    20581 cggacgcggc cggcggcccc ggcagctggc acgtcacggt ggacgggcgc ccgctgcacc
    20641 tgatgcgccg cgccgacggc acctggatga gcatggtcga ccactcccgc tcgtacccca
    20701 ccccgctgga ggcggcccgc gcggccgtcg acgcactccc gccggggcag cggctgagcg
    20761 ggacgggcgg cggacacggg cacgggggag gccgccatgg tgtacacgcg taaggacgtc
    20821 agcaccctga cccgcgccga gcggcagcgg ttcgtacggg ccctgctgga ggtcaaacgc
    20881 cggggcgagt acgacgagtt cgtgcgcatg cacatcgagt acttcgtccc cgacggggag
    20941 gacggactgc gcgtggccca catgaccccg tccttcctgc cctggcaccg gcagttcctg
    21001 ctggaactgg agcgggcgct gcagcgggtg gacgcctcgg tcaccgtgcc ctactgggac
    21061 tggaccaagg accgccgcgc cacctccgtg ccctggaccg ccgacctgct cggcggcaac
    21121 ggccggtcct cggaccacca ggtgacgacc gggccgttcg cctacaggga gggcaactgg
    21181 accctccggt acaacatcac cgacacccgg ttcctcaccc gggacctcgg ccgccgccgc
    21241 gcccccatcc aactgcccac caagagcgac ctggaatggg cgctgaagga ccccgtctac
    21301 gacgccgcgc cctgggactc gacgtcctcc aaggggttcc gcaacaagct ggagggctgg
    21361 ggacccgggc ggggcagcac ctcctggcgc aaccacaacc gggtgcaccg ctgggtcggc
    21421 ggggtcatgg tcggcggcgc ctccgtgaac gaccccgtct tctggctgct gcacgccttc
    21481 gtcgacctcc agtggtcccg ctggcaacgc cgccaccgca ccacccgcta ccttccggcc
    21541 caaccacccg gcgagagcaa cccccaacac ggacgcatca tcgcccgcca ccagaaactc
    21601 cccccgtggg acgtgacccc ggatcagttg gaggacctca gccacattta ccggtacggg
    21661 tgaggcaggg accggagcta aagcccagcc cccgtaagcc ggaatggcct gccgggccgg
    21721 ggatttctcc ttcggtcggg agctatcgaa gcgtcgggtg ctccgagggt cattcaccgc
    21781 ggccgctggc ccgggggccg tggggatggg cgcggatgag gacgttgcag tccgagacgc
    21841 gcgagccgtc ccgtgcggcc cgtgcggcct cccgctcccg ggcgaggccc tggcaggtcg
    21901 cgcaccccgc caccgggccg ggctcggttg ggagcagccc caggacgggg gccgggctca
    21961 tggtggtacg gggaatctgc cgaacgcctc cctcaacccg agcagccctc tgacgctcga
    22021 tcttcagttg gagggcaaca ccgtcaccgg cacatggacc gaacagaccg caccggacgg
    22081 gtactaccgt ggcgcccggt acttcggcgc gctccagatg ctcgtcgagc cgaccggccg
    22141 gcgcatggcg ggcaagtggg tcggcttcgg caaggaattc gacgtgaaca ccgggccgtg
    22201 ggaattgcgg ctcatggaca catcgaccag caaggcgacg ttggaggcgt acagtcgccc
    22261 acccgagtga cgcccggagg tgacggttcg ctccctgcac ggaacccgct cgccgtggca
    22321 cccggggcta gacgagtagt tccgatgtgg ctcagtggtc gcaggcgatc agtgagcggg
    22381 tgacgggtgc gccgatggtg cggttgtgcc agatcgcgca ggtcatcgcc aggatccgct
    22441 gagccacgcg gacaccgacg ccttcgatcg tgcgtccgcc gtgttgttcc aggtcgagct
    22501 ggcccttgag ggtgtcgttg accgactcga tcaactgccg caccgtcttg agcagggctt
    22561 ctcccggccg cggggtgcgg ttgcggtagg agggccgcag cagactgatg ccgcgggcgg
    22621 ccaggaagcg gtcgagttcg gtggcggtat agcccttgtt cgccaggatc agcaggccgg
    22681 gccggtgggc ggccaggtgc ggttcgttgt cgatgagggc ggccaggatc tgacgttcgt
    22741 cgatcttggg gtcggccagg gcccaggtga ccggcagtcc ggccggggtg cataccaggt
    22801 gcagcttcag gccccagtag aagcgcgagt gggatcggca gtagccgtag ccggcccagc
    22861 cggccaggtc ggagcgtttg acggtctcgc gggagcaggc gcattcgacg ggggtggagt
    22921 ccacgatcca tacgtcgtcc agccatagat cggtgtcggc ggccagcgat cggatggcct
    22981 gtttgaccag gcccagagcg gctcgcagcc gtttgttgta ggccgggcgc tgaggcaggc
    23041 aggggaacat cccgtgcagg tgggcgtggg cgaagcgcag ccagcgggcc tcgcagtgga
    23101 aacccggcat ggcctgggcc acagccagag tgatcagttc cgcgtcggtc agcttcggcg
    23161 gccggccacg ccgtcgcggg gtcttcaaat ggtcgtcgat atgcacgtac agtgccgtca
    23221 agagggtgtc taactcggtc gtcacaaccc gatgttggac accctcccta cgtctgagaa
    23281 ccccgcattc ggaactactc gtctaggccg tttctttcgg atcagcgtag ggaagcaagg
    23341 gcgggcacat gccgaggccg gtccggtctg cttccgctgc gccgggcggc gtcatttgtg
    23401 gggccaagcc ctctactccg cggccacgat gcgctccact gcggccgtca ccagttgttc
    23461 acgctcttcc tctgtgaaga cgtccggcag ggtgagctgc tcaacgatca gccagttcag
    23521 cgtcagcatg agcagcttga ccgccgtggc gtcgccaggg aggccggaag cctcgtgata
    23581 ggcgacattg gcgtcgacat cggcccggac tcgctcagtg aggaccttgc gcagttcggg
    23641 gcggcgggtg gcctcaaggc ggagttccag cagcgcgagg taaccggtgc ggaaggaggc
    23701 gatgcggccg acgagctcgc gcatcagttc ggcgtaggtc ccccggtggc ggtcggccgc
    23761 ccgctggcgg gcgatcgtgg cctcgtcggg ctggagtcgc tcgtaaaccc gggcgccggc
    23821 ctcagtgaac aggtcgtcgc ggctggcgaa gtagttggac gccgtgccgg cgggaacggc
    23881 tgcctcggca tccacagccc ggaaagtcag gccgcgtgcg ccttctcggg ccagcacctc
    23941 gatcgccgcg tcaacgaggg ccgcgcgccg ctggtcgttc cgtctcacca ttgacaccac
    24001 tccaggtgta gtactacgtt caaaccactt cagtcatagt actacgtgtg ggggatcact
    24061 atgcgaaagc tcgtgtacta catcggcgtc tcgctcgacg gccgcatcgc cggccccggc
    24121 ggcgaattcg acttcttccc gcagggcgac gagcagcagg ccgctgccta ctcgacctgg
    24181 atgaacgcgc tgtacccgga gaccatcccg accgcttacc gcgcggctgt cggcgtcgcc
    24241 gacgcaccta accggcgttt cgacaccgtc gtcatgggcc tcggcaccta ccgcctctcc
    24301 gtcgacaacg ggatcaccag cccgtacgcg cacctgcgcc agtacgtcgt gtccagcacc
    24361 ctcaagccgg acaccgaccc agccgtcacc gtcgtgccga gcgacccgcg cgccctcatc
    24421 cgcgagctca aaggcgagat ggccgctggc ccagacatct ggctctgcgg gggcggaagg
    24481 ctcgcgggca ccctgttgcc cgagattgac gagctgctga tcaagaccta tccggtcgtt
    24541 gccggtaccg gaattttggt agtcgacggt gccttcgacc ccaccgtctt caacgtcgcc
    24601 gaacgcaccg ccttccccaa cggggtcacc ctcacccgcc tcacccgccg ctaggcagtt
    24661 tcggttcagc gggcggacca gaagaagatg cccgcgatat ggagtccggc caggtagatg
    24721 gtcgctgtct tctcgtagcg ggtggcgata ccgcgccact gcttgaggcg gttgatgcac
    24781 cgctcgacgg cgttgcgctg cttgtaggcg tcgcggtcga aggccggtgg cctgccgcct
    24841 tggctgccgc gccgctgccg gtgggcctgc tggcccgccg ggacagggat cactgcgcgg
    24901 atcccgcgct tgtgaaggtg ggcgcggatc gcgcgcgagg agtacgcctt gtccgccaga
    24961 accacatctg gcctggtgcg gggccgtccg cgtcggcgcg gaacacgcag acgtgccatc
    25021 acctgcgcga atgcgggtgc gtcgccggcc tgcccggcgg tgagatgaaa ggccaggggc
    25081 cggcagctgc cgtcggcggc gaggtggatc ttcgtggtca atccgccgcg ggaccggccg
    25141 atggcgtggt cgtcgggctc gccgaccggg gccccttttt gcgggccccg gccgcatgct
    25201 ggtgagcgcg cacgatcgta gagtccaccg acacggccca attgaggtcc tcctccgcgt
    25261 cggcctgggc gatcagcgcg gtgaacaccc gctcccaggt gccgtcgacg gcccacatcc
    25321 gcagccggtt gtagacgcct cgccagttgc cgtacttctc cggcaggtgc acccactgcg
    25381 ttccggtctg gaacttgaag gcgatcgcgt tgatcacctc acggtgatcc cgccagcggc
    25441 caccccgctt cggtgtccgg tcgggaagta gtggctcgat ccgcgcccac tgcgcatcag
    25501 tcaacggcac gccgggacca acgatccgat gatccaaacg aaacggccgt tgtgctgtcc
    25561 cgggacgttg gtgacacgcg tgctgggtgc ttgaacgggt gagggccttc tgggttcggt
    25621 gtggattgcg acatctaccg ccgaccgcca ggaggccctc gtgtcccacc gtaacgcccc
    25681 gctgaccccg accggcaggc tgcgtctggc ccggtgtgtc gtggacgaag gctggccgtt
    25741 gcggcgggcc gcggaacgct tccaggtcag ccacaccacc gccgcccgct gggccggccg
    25801 ctaccgacag ctgggcgagg ccggcatgca ggaccgttcc agccgcccgc accacagccc
    25861 gcgccggacg cctgccaccg tcgagcagca ggtcctgcgg ctgcggcgcg agcaccggat
    25921 cggtccggtg cggctggccg cccgctgcgg catcgccgcg tccaccgctc accgcatcct
    25981 cgtccggcac cacctgcccg ccctggccac gctggaccgg gccaccggcg aacccgtgcg
    26041 ccgctacgaa cgctcacggc ccggggaact ggtctacatc gacgtcaaga agctcggccg
    26101 cattcccgac ggcggcggtc acaaggtcct cggccgggcg gccggcagcc cgaacaagga
    26161 ccgccgcaac ggcgcgggat acgcctacct gcacaccgcc ctggacgacc actcccgcct
    26221 cgcctacacc gaagacctgc ccgacgaaac cgccgccacc tgcgcgggct tcctcacccg
    26281 agccgtggcc tggttcgccg cacgcggcgt caccgtcgag cgggtcctga ccgacaacgc
    26341 ctgggcctac accaagaaca cctggcgcca gacctgccac gagctgggca tcagcccgcg
    26401 ctggacccgg ccctggcggc cgcagaccaa cggcaaggtc gaacgcttca accgcaccct
    26461 gctggacgag tgggcctacg cacggcccta ccggtcagag accgaacgcc gcgaagcgtt
    26521 cccacagtgg ctgcactcct acaatcacca ccgcggacac accgcgctga aagggcaacc
    26581 acccgccagc cgcgtcccca acctcacagg gcaatacacc tagccttctt ggagctcagc
    26641 ccgcatgagt tccccgaact gcctgacgag tttctgggtg ctcaggagtg tcgcctcctc
    26701 ggcagtcgcc tgccgcggtt ccggctgctc cacggcgtgg tcgacggtga tgccgatcgc
    26761 ggtcctgcgg ttttcacgac acccgctccg gcgtgcggct ccccctcggg aaggacgaca
    26821 agcgtgccgc cggtgaggcc gtacggcttc cagctcgtgg acgactgcgg cggcctgccg
    26881 tcggccagga actcgcacgt cgtccggacg cacaggtcgc ctggcgatgc caggtgcatc
    26941 gacgggcagt tgccggatct cgagcggcga ctggaagccg cgggtggcct ccaggaggcg
    27001 gaggtgccgg gcgttggctg atcttttccg gtcggggaca ttgacacacg ccacgggcac
    27061 ctgcgaaaac ccggtgacgg ccgtacggcc ctggagtccg tccttggtca tcgagaggcg
    27121 tccggggctt cgccgcttcg ccccgcgcac atcctgacca gcgaaaagcc ctcccgagcg
    27181 agcgggaggg cggagactgg cgcccccggc aggactcgaa cctgcggcca agcgcttaga
    27241 aggcgcctgc tctatccact gagctacggg ggcctggggt ggtggccttc gtcgcggggc
    27301 cgtggtggct gatccgtgac gtcgccgggg acaaggatag ggctcccggc tccctgtccc
    27361 ggttgcttcc cctccgtggc tcgatgtgga ggttcggtga agcgatcctg ataatcgcag
    27421 gcaggtgcga atcgtgcacc gcttttggcg ccccgcgcat cgggtgttgt gcactcgtta
    27481 tgcctgggcc gtgtcggcgt cccactcgcc ccttgtgccc cttgtgtcct gtcggcgcgc
    27541 agacatgctc atatgcttca gaattcccct aaaattgggc attcttcgca tgtggtgacc
    27601 ttggacgtac ggcctcagct gctcgacgca ctctccgccc tgcgcgaccg tgtcgcggcc
    27661 gcacgcttcc cgctgcccct ggcaggggcc ccacgcgcgc gtgccaaccg ggacgaactg
    27721 ctcgcgcagc tcgacgacta tctggtgccc cggctgaagg agcccgaggc cccgctgctc
    27781 gccgtcatcg gcgggtccac cggggcgggc aagtccacgc tgctgaactc gctcgtgggg
    27841 cgccgggtca gcgaggcggg ggtcctgcgt ccgacgaccc ggacgccggt cctggtctgc
    27901 catccggagg accaccactg gttcagcggc acgcggatcc tgccc
//
