LOCUS       LN831790               29273 bp    DNA     linear   BCT 17-JUN-2020
DEFINITION  Streptomyces leeuwenhoekii strain C34 (= DSM 42122 = NRRL B-24963)
            genome assembly, chromosome: chromosome.
ACCESSION   LN831790
VERSION     LN831790.1
KEYWORDS    .
SOURCE      Streptomyces leeuwenhoekii
  ORGANISM  Streptomyces leeuwenhoekii
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-02-26 04:50:55
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 5455247
            Orig. end    :: 5484520
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..29273
                     /aStool="rule-based-clusters"
                     /category="saccharide"
                     /contig_edge="False"
                     /core_location="[10000:19273]"
                     /cutoff="20000"
                     /detection_rule="minimum(2, [Alpha-amylase,
                     Alpha-amylase_C, Bac_transf, CBM_48, Capsule_synth,
                     DegT_DnrJ_EryC1, Epimerase_2, Glyco_tran_28_C,
                     Glyco_transf_28, Glyco_transf_8, Glyco_transf_8C,
                     Glyco_transf_9, Glycos_transf_1, Glycos_transf_2,
                     Glycos_transf_4, MannoseP_isomer, PIG-L, Poly_export,
                     Polysacc_synt, Polysacc_synt_2, RmlD_sub_bind, Wzy_C,
                     dTDP_sugar_isom])"
                     /neighbourhood="10000"
                     /product="saccharide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..19273
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="minimum(2, [Alpha-amylase,
                     Alpha-amylase_C, Bac_transf, CBM_48, Capsule_synth,
                     DegT_DnrJ_EryC1, Epimerase_2, Glyco_tran_28_C,
                     Glyco_transf_28, Glyco_transf_8, Glyco_transf_8C,
                     Glyco_transf_9, Glycos_transf_1, Glycos_transf_2,
                     Glycos_transf_4, MannoseP_isomer, PIG-L, Poly_export,
                     Polysacc_synt, Polysacc_synt_2, RmlD_sub_bind, Wzy_C,
                     dTDP_sugar_isom])"
                     /neighbourhood="10000"
                     /product="saccharide"
                     /protocluster_number="1"
     cand_cluster    1..29273
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(2, [Alpha-amylase,
                     Alpha-amylase_C, Bac_transf, CBM_48, Capsule_synth,
                     DegT_DnrJ_EryC1, Epimerase_2, Glyco_tran_28_C,
                     Glyco_transf_28, Glyco_transf_8, Glyco_transf_8C,
                     Glyco_transf_9, Glycos_transf_1, Glycos_transf_2,
                     Glycos_transf_4, MannoseP_isomer, PIG-L, Poly_export,
                     Polysacc_synt, Polysacc_synt_2, RmlD_sub_bind, Wzy_C,
                     dTDP_sugar_isom])"
                     /kind="single"
                     /product="saccharide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..29273
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="saccharide"
                     /region_number="35"
                     /rules="minimum(2, [Alpha-amylase, Alpha-amylase_C,
                     Bac_transf, CBM_48, Capsule_synth, DegT_DnrJ_EryC1,
                     Epimerase_2, Glyco_tran_28_C, Glyco_transf_28,
                     Glyco_transf_8, Glyco_transf_8C, Glyco_transf_9,
                     Glycos_transf_1, Glycos_transf_2, Glycos_transf_4,
                     MannoseP_isomer, PIG-L, Poly_export, Polysacc_synt,
                     Polysacc_synt_2, RmlD_sub_bind, Wzy_C, dTDP_sugar_isom])"
                     /tool="antismash"
     gene            769..5280
                     /gene="sle_46370"
     CDS             769..5280
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VWE1"
                     /db_xref="InterPro:IPR003029"
                     /db_xref="InterPro:IPR004659"
                     /db_xref="InterPro:IPR012340"
                     /db_xref="InterPro:IPR019307"
                     /db_xref="InterPro:IPR022967"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VWE1"
                     /gene="sle_46370"
                     /product="Ribonuclease E"
                     /protein_id="CQR64095.1"
                     /transl_table=11
                     /translation="MLEPTEPTQGSEPNTPSDSLPPRRRRRAASRPAGPPVASSDTPVE
                     TVTPAIPAAGSDALAQAQVTADADAVGDEEESAAQEAVAQQAAAPDAEEPAPAGRRRRR
                     VVRRASAPAGAPASAETAETVLPAAPAAEAAPAAVTGAPEAAEAVQAPEAAESAAPRRT
                     RRRATRTVTSPSATGQPAQSADAAQSAEAAPAVEPAPAAAPAGTADETPDTPGTPDTAG
                     TPAAESAGEEAAAPRRTRRRATRRVSAPAGAPETAASSAEAPAQAPVQAEAPAQDEAPA
                     QAEAAAPARTRRGRKDTAVTQAPEAPAAEAPEQAAQAEQADQAAQAAPAEEPAPRRTRR
                     RTVRKAATGFAEPARPAGASDSEADAPRRPARPAVAVFQPPVFAEPKFQTPERAAAEAA
                     AVAAGAERVEETEDTEAAEATEEFTQEQATGSRRRRRRRGAAADERPEPVADEEPEAPE
                     ARETEAPEEPEAEEPEESEDEDAEGAEGAEGAEEGGSRRRRRRGGRRRRRGESGEGADA
                     DSEELAAEQAAQDAEDTAEQVEEDTEEGTDEDGADEHAFAGNGTSSSRRRRRRRRRAGD
                     TSADTEPSADDPERTVVKVREPRKPAEPSDEVQSIKGSTRLEAKKQRRREGREQGRRRV
                     PIITEAEFLARREAVERVMVVRQHGDRTQIGVLEDGVLVEHYVNKEQSTSYVGNVYLGK
                     VQNVLPSMEAAFIDIGKGRNAVLYAGEVNFEALGMSGGPRRIESALKSGQSVLVQVTKD
                     PIGHKGARLTSQVSLPGRYLVYVPEGSMTGISRKLPDTERARLKTILKKIVPEDAGVIV
                     RTAAEGASEDELRRDVERLQAQWEEIQKKAKNGNAPTLLYGEPDMTVRVVRDIFNEDFS
                     KVIVSGDDAWQTIHGYVSHVAPDLAERLQRWTSEVDVFATYRIDEQLAKALDRKVWLPS
                     GGSLVIDRTEAMVVIDVNTGKFTGQGGNLEETVTRNNLEAAEEIVRQLRLRDLGGIIVI
                     DFIDMVLESNRDLVLRRLLECLGRDRTKHQVAEVTSLGLVQMTRKRVGQGLLESFSETC
                     VHCNGRGVIVHLDQPSAAAGGGKRRKRARAGAGEQPHEHEAVAVETAETAEQEAEAESE
                     AEVAAEAAEPAALPAPDFAPDEELYSSIAEAEAAAGRGRTRRRTSRRASAPAGAPRGEA
                     APAGKGRAEKPRKAAAEQPQDEKAVVAASAEQGAGAEVPTAQDVTAEQEAARPVRQESA
                     AEALAEPAAVEDAVVAAPAPEAPAAEAAVTEEEAAPKGRTRRRATRRASAPAGSPAGAE
                     AAVVTVPESAPAAPEAAPQAEEAAPAASAEQPETAAEPAAPARPRRRAVRKAAAPTAPA
                     EAAVVVLPAATEPAAEPEAPAQEAPVQEAAASEAPAAEPAAEGPEAAEAAASEAPAAEP
                     AAEGPEAAEAAEEAVAAKKTARKTAKKATAKKAATKKTAATKKTAATKAATAKKTAAKK
                     TTAKKAAAKKTATKTAARKTAAKKTAAAEQTAPSVSASTDEV"
     gene            5407..6159
                     /gene="sle_46380"
     CDS             5407..6159
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W4Z4"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR029044"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W4Z4"
                     /gene="sle_46380"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 68.2; E-value:
                     1.1e-20)"
                     /gene_kind="biosynthetic-additional"
                     /product="Nucleotidyl Transferase"
                     /protein_id="CQR64096.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 6.8e-10, bitscore:
                     38.1, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLILAAGAGRRLRPYTDTLPKALVPVGPEGAEDSLTVLDLTLG
                     NFAEVGLTEAAIIVGYRKEAVYARKEALEAKYGLKLTLIDNDKAEEWNNAYSLWCGREA
                     LKDGVILANGDTVHPVSVEKTLLAARGDGKKIILALDTVKQLAEEEMKVVVDPAKGVRR
                     ITKLMDPAEATGEYIGVTLIEGEAAAELADALKATFERDPQLYYEDGYQELVDRGFTVD
                     VAPIGDVRWVEIDNHDDLAKGREIACRY"
     gene            6147..7208
                     /gene="sle_46390"
     CDS             6147..7208
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W2M5"
                     /db_xref="InterPro:IPR016205"
                     /db_xref="InterPro:IPR032837"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W2M5"
                     /gene="sle_46390"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181:dehydrogenase (Score: 79; E-value: 5.4e-24)"
                     /gene_kind="biosynthetic-additional"
                     /product="Glycerol-1-phosphate dehydrogenase [NAD(P)+]"
                     /protein_id="CQR64097.1"
                     /sec_met_domain="Fe-ADH (E-value: 1.8e-19, bitscore: 68.4,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLLTRLIPAPVVVDIRAGALDDLTSVLADQRISQSGRLAVAVSG
                     GSGARLRERLAPALPGAEWFEVGGGTIDDAVRLADAMKGGRYDAVVGLGGGKVIDCAKY
                     SAARVGLPMVAVATNLSHDGICSPVSILDNDAGRGSYGVPTPIAILVDLAVIREAPIRF
                     VRSGIGDAVSNISAVADWELAHRVNGEKVDGLAAAMARQAGEAVLRHPGGCGDDGFLTV
                     LTEGLVLSGIAMSIAGHTRPSSGACHEISHALDLLYPRRAASHGEQVGLGAAFAMHLRG
                     DHEGSRLMAGVLRRHGLPVLAEEIGFDDDEFVRAVEFAPQTRPGRYTILEHLELSPARI
                     REAYADYAASVDD"
     gene            7399..7719
                     /gene="sle_46400"
     CDS             7399..7719
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VZS9"
                     /db_xref="InterPro:IPR001787"
                     /db_xref="InterPro:IPR018258"
                     /db_xref="InterPro:IPR028909"
                     /db_xref="InterPro:IPR036164"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VZS9"
                     /gene="sle_46400"
                     /product="50S ribosomal protein L21"
                     /protein_id="CQR64098.1"
                     /transl_table=11
                     /translation="MYAIVRSGGRQHKVAVGDIVEVDKISTAKVGDTVELSTLLVVDGD
                     SVTSDPWVLAGIKVQAEVVDHHKGQKIDILRYKNKTGYRRRQGHRQQYTAIKVTEIPTA
                     AK"
     gene            7734..7988
                     /gene="sle_46410"
     CDS             7734..7988
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VU95"
                     /db_xref="InterPro:IPR001684"
                     /db_xref="InterPro:IPR018261"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VU95"
                     /gene="sle_46410"
                     /product="50S ribosomal protein L27"
                     /protein_id="CQR64099.1"
                     /transl_table=11
                     /translation="MAHKKGASSTRNGRDSNAQRLGVKRFGGQVVNAGEILVRQRGTHF
                     HPGSGVGRGGDDTLFALQAGSVQFGTHRGRKVVNIVPVA"
     gene            8185..9621
                     /gene="sle_46420"
     CDS             8185..9621
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VWE5"
                     /db_xref="InterPro:IPR006073"
                     /db_xref="InterPro:IPR006074"
                     /db_xref="InterPro:IPR006169"
                     /db_xref="InterPro:IPR014100"
                     /db_xref="InterPro:IPR015349"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="InterPro:IPR031167"
                     /db_xref="InterPro:IPR036346"
                     /db_xref="InterPro:IPR036726"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VWE5"
                     /gene="sle_46420"
                     /product="GTPase obg"
                     /protein_id="CQR64100.1"
                     /transl_table=11
                     /translation="MTTFVDRVELHVAAGNGGHGCASVHREKFKPLGGPDGGNGGRGGD
                     VILTVDQSVTTLLEYHHSPHRKATNGKPGEGGHRSGKDGQDLVLAVPDGTVVLDKAGNV
                     LADLVGHGTSYVAAQGGRGGLGNAALASARRKAPGFALLGEPGDVCEIVLELKTVADVA
                     LVGYPSAGKSSLISVLSAAKPKIADYPFTTLVPNLGVVTAGSTVYTIADVPGLIPGASQ
                     GKGLGLEFLRHVERCSVLVHVLDTATLESDRDPVSDLDVIEEELRQYGGLDNRPRLVVL
                     NKIDVPDGRDLAEMVRPDLQARGYRVFEVSAVAHTGLKELSFALAELVAAARAARPKEE
                     ATRIVIRPKAVDDAGFTVTREEDGLFRVRGEKPERWVRQTDFNNDEAVGYLADRLNRLG
                     VEEELMKAGARAGDGVAIGPEENAVVFDWEPSVMAGAEMLGRRGEDHRLEAPRPAAQRR
                     RDRQAERDDAQREFDDFEPF"
     misc_feature    8198..8211
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.64"
                     /tool="antismash"
     gene            10001..12034
                     /gene="sle_46430"
     CDS             10001..12034
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W4Z8"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W4Z8"
                     /gene="sle_46430"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     saccharide: Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 165.3;
                     E-value: 4.1e-50)"
                     /gene_kind="biosynthetic"
                     /product="Exopolysaccharide phosphotransferase SCO2592"
                     /protein_id="CQR64101.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 2.5e-40,
                     bitscore: 136.5, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAFLVRDLCHMGGVVSATQNLAGALADRHEVEIVALRKVRDES
                     YFPLDPRVSVRVLSDLRPHSPVSDLDDPLVEKWPLVYPPNTGAKKPVVSRLAERRLLEY
                     LATTDADVVVSSSPRNTIMLAQAPGTYLKVAQEHSMPSIYAKDIKERLFPAYLSLDALT
                     ALTPEEVESIGRQVPAVRDRLAVMPNCVPASPIRSKGTNKVVVCAGHLTDNKNHALLVE
                     AFAKVHAQAPDWTLRIYGSGAEKARLRARIEELGLSNSILLMGQTAPVTPEFGKGSIFV
                     LPSKREAFGNVIVEAMAAGLPVVSTDADHGPRNILTPGEDGLLVPRGDVEEMARAILRL
                     VQDDELRQKMAANAVRGAERFHETASRERFEAILERALARKALPRHATARVDDRGSVHI
                     EVGPLPERARGAELVLRRSGKNGEEHRFPLSDSGEALVAWDAGLPHGTWEAALASPSGG
                     EVPLTTDGYGCDTRDLLAVELPRPHGHPLALLLPHRHDDGRLRVRSALRAVHAEVGPVR
                     VDDQAVRLRAELWGATLGRGAVVEAVHRRDKERVLTFEARDAGDGAFEAVVDCAALARE
                     HGEEDGKEAIWDFWIRPEEGAPRAALAKLATDVLKPIDVFTFPRPVLTSGAVARPSVVR
                     RAARRARRSLGATPAALPRPVRTELRPYYTALSQFAVKTVRL"
     gene            complement(12143..15703)
                     /gene="sle_46440"
     CDS             complement(12143..15703)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W2N0"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="InterPro:IPR007554"
                     /db_xref="InterPro:IPR029044"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W2N0"
                     /gene="sle_46440"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     saccharide: Glycos_transf_2"
                     /gene_kind="biosynthetic"
                     /product="CDP-glycerol:poly(glycerophosphate)
                     glycerophosphotransferase"
                     /protein_id="CQR64102.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.5e-37,
                     bitscore: 127.0, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPRLSVIVPIYDVERYLPACLDSLAAQTFRDFEVLMVDDGSPDD
                     SASIAAAYAERDPRFKLIRKENGGLGAARNTGIAHMSPQAEYVTFVDSDDLIPPDAYRL
                     MVSSLDESGSDFATGNVFHLKGEKTWQVPLLRMLAGEARRATHISRYGKLVADRIACNK
                     VFRRTFWEKHGFAFPEGRLYEDTPVTMRAHYLADAVDVISEPCYYWRLREGESAPSITQ
                     RRTDPAGVRDRVTSVLEISAFLAEQPGEMFARLKEEYDTRVLKDDLRLFLNVVPDGDEE
                     YRAEFLRSANRFLDRIDPKVVMALPAQLRVQWLLVRKHKLDELITLLAGQRRKEAVEVS
                     GLVRKYASFPSLADADLDFPRKALRIDQDLRMRAPLQEVTWSEGKLVLSGNAWIDKIDL
                     ASKHSSVKVLQLRKDKSRRRILLPARNIHRPECTTNSGQDRYNYDWAGWEVTIDPARLR
                     KGGEWQEGLWHVGLGLYASGLVRRAAVQSSGGAACNFPPYHWLSPDFRLLPSVERGALK
                     IRIERVRALITGRTVEGDRIVVTGEIRVPLAAGENVVLRVRNQKGADVHEYPVTVTDEG
                     GTHRFSVEVPVADVALVFHDGVDAKAQPENRTWSTALIARDPQGAERQFSTVLQEGLPD
                     ARFNLPASLGERAELCELAIVAGHTGYLKFAGRTRRATIDRVGVEDGRITIAAHTDPRL
                     TGARFLLKPRNRFEERFVEARWSEDGRFEVAFDPSTLGGGGNVPLRAGRWNLWLRPEDG
                     APDVPFVTDRLAADQFPLRAELNGRRYWLENRWADFPQLNCRSELSDLERGPFRQKQLR
                     RDLYQPLRRQPLRDQVFYLSYNGKQFSDSPKAMYQELVRRGSDLKHLWAVRDGQVILPE
                     GVEPVRMWGTEWYEALATSRYIVTNGHLPDWIERRPGQVIVQTWHGTMLKKIGHDIDTL
                     HFDRRYQEKLALEAKQWSLVVSSNRFSTPILKRAFSYDGEILEAGYPRNDYLYSPDKDR
                     IAERVKKQLGLPEGKKVVLYAPTWRDDLSHSAGQYLFDLRIDLEDAQRRLGDDHVLLIR
                     RHSNVVDAVPGAGNGFVWDVSEYPDIADLYLAADVMITDYSSVMFDYAHLRRPMLFFTY
                     DLEHYRDTLRGFYFDFEQDSPGPLIATSKELVDALRDIDQVSAEYQERFERFHHLFCDL
                     DDGNASTRVVDRMLEQSREL"
     gene            complement(15727..17958)
                     /gene="sle_46450"
     CDS             complement(15727..17958)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VZT4"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="InterPro:IPR007554"
                     /db_xref="InterPro:IPR029044"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VZT4"
                     /gene="sle_46450"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     saccharide: Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 69; E-value: 8.3e-21)"
                     /gene_kind="biosynthetic"
                     /product="CDP-glycerol:poly(glycerophosphate)
                     glycerophosphotransferase"
                     /protein_id="CQR64103.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.1e-36,
                     bitscore: 124.0, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKLSLVVPVYKVQGYLPECLDSVLGQDYTDFEIIAVDDCSPDGS
                     GAILDEYARRDARIHVIHLTENVGLGRARNAGLEKAQGEYVLFLDSDDTLSDGALTAIS
                     ERLAATGDPEILVFDYARTYWDGQVRPNQRADLLKSDGPEVFRLAERPQLLDLLQIVWN
                     KAYRRDFITRTGLTFPPGYYEDAPWTFCSLISAERIAVLDRVCVLYRQRREGGNILKTV
                     SRKHFDVFDQYRRVFDFLDAHEELDRWRGPLFRKMVDHYLTVLERPGRLPREARAEFFH
                     RASADYRARLPKGFQKPAGGRGHKYAMLERDAYAAMMSASTAVKLRRTVRKRTRDALNR
                     SKRSAMGVHYQSQLRLPLDENLVLFSAYWSRSVSCNPAAIDAELARLAPHLRRVWAIRP
                     DAVDQVPKGVEYVRVGSRAYWTALARAKYLVNNVNFADAVVKREGQIHLQTHHGTPLKT
                     MGLDQQKYPASTDMNFEKLLERCDRWDYSISSNRFSTAIWERVYPCSYVSLETGYPRND
                     VLVNAGAEEVRRARAALGLADGAKAFLYMPTHREYQPGFTPSLDLARLAEELGPDVTLL
                     LRGHYFYGSSPHIAELRRSGRIVDVSGHPRVEELYLAADALITDYSSAMFDYAVLDRPI
                     IVYAPDWDIYSAVRGTYFDLLQEPPGAVATSQAELIRLLGSGDYDSRDAAGRRDAFRRR
                     FCEFDDGHAAERVVRRVFLGDQTPLPFVPFDERSHAPTPAQALEPVERA"
     gene            18302..19273
                     /gene="sle_46460"
     CDS             18302..19273
                     /NRPS_PKS="Domain: NAD_binding_4 (65-209). E-value:
                     4.8e-10. Score: 30.8. Matches aSDomain:
                     nrpspksdomains_sle_46460_NAD_binding_4.1"
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VU98"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR005886"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VU98"
                     /gene="sle_46460"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     saccharide: RmlD_sub_bind"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     saccharide: Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     261.4; E-value: 2e-79)"
                     /gene_kind="biosynthetic"
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="CQR64104.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 7e-16, bitscore:
                     56.8, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 5.1e-13,
                     bitscore: 47.4, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSWLVTGGAGYIGAHVVRAMAAGGERVVVYDDLSTGSADRVPDGV
                     PLVVGSVLDASLLARAIRDHAVTGVVHIAAKKQVGESVEQPLRYYRENVTGLRTLLEVM
                     TDAGVGKLVFSSSAAVYGMPDVELVTEDTPCAPMSPYGETKLVGEWLIAATARAHGIRA
                     ASLRYFNVAGAAEPALADAGVFNLIPMVFERLEAGEAPRIFGDDYATPDGTCVRDYIHV
                     EDIASAHLAAARRLGEAAEGTNLVLNIGRGEGSSVREMVDRILKITGHEHLTPAVAERR
                     PGDPARVVASADRIRRELDWSAHHDLDDMIRSAWQGWRHLRG"
     CDS_motif       18305..18385
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sle_46460_0001"
                     /evalue="1.90E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="sle_46460"
                     /protein_end="28"
                     /protein_start="1"
                     /score="17.3"
                     /tool="antismash"
                     /translation="SWLVTGGAGYIGAHVVRAMAAGGERVV"
     aSDomain        18497..18928
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sle_46460_NAD_binding_4.1"
                     /evalue="4.80E-10"
                     /label="sle_46460_NAD_binding_4.1"
                     /locus_tag="sle_46460"
                     /protein_end="209"
                     /protein_start="65"
                     /score="30.8"
                     /tool="antismash"
                     /translation="AVTGVVHIAAKKQVGESVEQPLRYYRENVTGLRTLLEVMTDAGVG
                     KLVFSSSAAVYGMPDVELVTEDTPCAPMSPYGETKLVGEWLIAATARAHGIRAASLRYF
                     NVAGAAEPALADAGVFNLIPMVFERLEAGEAPRIFGDDYA"
     gene            19437..20543
                     /gene="sle_46470"
     CDS             19437..20543
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VWE7"
                     /db_xref="InterPro:IPR001048"
                     /db_xref="InterPro:IPR001057"
                     /db_xref="InterPro:IPR002478"
                     /db_xref="InterPro:IPR005715"
                     /db_xref="InterPro:IPR011529"
                     /db_xref="InterPro:IPR015947"
                     /db_xref="InterPro:IPR019797"
                     /db_xref="InterPro:IPR036393"
                     /db_xref="InterPro:IPR036974"
                     /db_xref="InterPro:IPR041739"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VWE7"
                     /gene="sle_46470"
                     /product="Glutamate 5-kinase"
                     /protein_id="CQR64105.1"
                     /transl_table=11
                     /translation="MGEARRIVVKVGSSSLTTAEGGLDADRVDALVDVLAKVRSGGERE
                     IVLVSSGAIAAGLAPLGLRRRPRDLARQQAAASVGQGLLVARYTASFARYGVRVGQVLL
                     TSDDMSRRAHHRNASRTLDKLLAMGAFPIVNENDTVATDEIRFGDNDRLAALVAHLVHA
                     DLLVLLSDVDGVYDGDPGRPGTARIAEVRRPEDLAHVEIGSAGKAGVGTGGMVTKVEAA
                     RIAAAAGIPVVLTSAVHAADALTGQDTGTYFHPTGKRSADRLLWLQHASTPQGALTLDD
                     GAVRAVVEGRKSLLPAGIAAVEGEFVAGDPVELRDGEGRAVARGLVSFDAKEIPRLIGR
                     STRELARELGPAYEREVVHRDDLVILHP"
     gene            20703..21170
                     /gene="sle_46480"
     CDS             20703..21170
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W501"
                     /gene="sle_46480"
                     /product="Conserved Hypothetical Protein"
                     /protein_id="CQR64106.1"
                     /transl_table=11
                     /translation="MRRVRPGAATSRGGAASRAAGEERALTSVAAGERHEREGPADAPR
                     LWHVTLSVSGARAPLPEVRRALEQLAHDHPFLLTSRYADDHAEIRYWEEARDLHDAAAV
                     ALRLWGEHRQTAGLPPWEIVGLEVIDRATYHQRIAAGYGPAPATPVGVHPF"
     gene            21232..22518
                     /gene="sle_46490"
     CDS             21232..22518
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W2N5"
                     /db_xref="InterPro:IPR000965"
                     /db_xref="InterPro:IPR012134"
                     /db_xref="InterPro:IPR015590"
                     /db_xref="InterPro:IPR016161"
                     /db_xref="InterPro:IPR016162"
                     /db_xref="InterPro:IPR016163"
                     /db_xref="InterPro:IPR020593"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W2N5"
                     /gene="sle_46490"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 68.9; E-value:
                     4.8e-21)"
                     /gene_kind="biosynthetic-additional"
                     /product="Gamma-glutamyl phosphate reductase"
                     /protein_id="CQR64107.1"
                     /sec_met_domain="Aldedh (E-value: 3.8e-22, bitscore: 77.1,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTLSPYDSMTPVTQAAYRAKAAAADLAPLPRAVKDDALLAIADA
                     LEVRTSEIVEANAQDVAKAREAGTSEAIVDRLTLTPERVRAIASDVRDVVALPDPVGEV
                     VRGSTLPNGIDLRQVRVPLGVVGIIYEGRPNVTVDAAALCLKSGNAVLLRGSSSAYRSN
                     TALVRVIRDAVGGAGLPADAVQLVPGESRESVRELMRARGLVDVLIPRGGASLINTVVQ
                     ESVVPVIETGTGNCHVYVDAAADLDTAIDILINSKAQRVSVCNAAETLLVHQDIAPEFL
                     PRALDALADAGVTVHADERVMAYAKDSRATVVEATAEDWETEYLSYDIAAAVVDSLDKA
                     VEHIRLWTSGHTEAIVTTSQQAARRFTQRVDSTTVAVNASTRFTDGGQFGFGAEIGIST
                     QKLHARGPMGLPELTSTKYIVTGDGHIRR"
     gene            22622..23350
                     /gene="sle_46500"
     CDS             22622..23350
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VZT9"
                     /gene="sle_46500"
                     /product="Conserved Hypothetical Protein"
                     /protein_id="CQR64108.1"
                     /transl_table=11
                     /translation="MRGWRDRGRRLAVVSGLFAVLVAPATAPAAAVPAGHPVGRSAARA
                     GAGPDEPDVAVVVTAGTGRTEAWRAGELAFDRLRGLLDPAYSGTERVPEEWAEGRYPRV
                     RFTVLWGLTGVGGWPQTRRAPGGDVAMLRQDQLFLAPDGTPWVRTDPAPDLPDDDIRWH
                     RVPRGEYDRLAGVGFMGLGGAQPAVGEAGAGEGGAREGVWWAAGGLALGVAGTLLTRRA
                     AARRGARPPRDEPRQELIDG"
     gene            23517..24263
                     /gene="sle_46510"
     CDS             23517..24263
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VUA0"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VUA0"
                     /gene="sle_46510"
                     /product="Conserved Hypothetical Protein"
                     /protein_id="CQR64109.1"
                     /transl_table=11
                     /translation="MLTTVGLRAGRGSRGRLLLVATEPRPRPRRATAGPAPSRPPDEFP
                     YRLPKLTPPVYSGTVPEDVGGTPFPDGWDGREPDSDPDRGAWDEEFASVVFDEAFVRAA
                     AVHEPTAVERLLAAAQARAEAAETEARRTHPAGERYDDGYGGFGHAPGLDALDDDGLDG
                     PGDPAGPYGRPLRWHRPVAWVLALVMGVGMVALAFAAVYRGGSSGGGERTPPPASTSPE
                     QGGATSPSVSAGHSRPAAVPVIPHSP"
     gene            24362..25432
                     /gene="sle_46520"
     CDS             24362..25432
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VWF8"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VWF8"
                     /gene="sle_46520"
                     /product="Conserved Hypothetical Protein"
                     /protein_id="CQR64110.1"
                     /transl_table=11
                     /translation="MGGPGDPPEGTPEGIPSGGEDEYRSVVFDESFVRAARLQEYSAQE
                     RMADHAPAVRRRPPLRRVRLPRQALVLVVLIAIAFGAAVFMGLRPPYQTPGGQEPAEPL
                     RMTVVPLAPQGRVPGTAETAHLFERSPAAEFRMGAEGVPLPAARRTAHFSDDQVLSALT
                     TAKDYIVRSGLDPEVLGGGPVRSVRVLVDPEQLGQFDASFKRPAADGRHAPTGWLVRFD
                     PSRVELADPGIRTNGTLRVAEADSATLEVTADHTFVYALRPAGQDRAEASLFTVRRELH
                     FRFDRDDLRLHQAQLVLSTLQAGPLSCAEDSANHLRPLLAGQTAKDGPPAGTDPYVTGR
                     ATALCGTLAAGAQPKV"
     gene            complement(25496..26680)
                     /gene="sle_46530"
     CDS             complement(25496..26680)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W505"
                     /db_xref="InterPro:IPR001915"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W505"
                     /gene="sle_46530"
                     /product="Peptidase"
                     /protein_id="CQR64111.1"
                     /transl_table=11
                     /translation="MSDGHQHSGPEKVPGRQRRRFPEISSRAYEHPADRSALVALRKLS
                     GFDTAFKALSGLLPERSLRLLFLSDSVRVSDRQFSHLNDMLRDACYILDLEKVPPMYVN
                     QDPTPNAMCIGLDEPIIVVTTGLVELLDEEEMRAVVGHEVGHALSGHAVYRTVLLFLTS
                     LAVRVAWIPLGNVAIMAVVTALREWFRKSELSADRAGLLAGQDLQASMRGLMKIAGGNH
                     LHEMNVDAFLEQADEYEAGGDLRDSVLKILNVLPRSHPFTTVRAAELKKWAASRDYQRL
                     MDGHYPRRGEDGDTSVRDSFRESASSYATQVRTSKDPLMKLVNDLAGGAGDLGERMRRG
                     FGGFTGSQPRPPKSPGGPGDAAGPEAPGGGGTPGGGETPGGGGTPGGRPPREED"
     gene            26806..26970
                     /gene="sle_46540"
     CDS             26806..26970
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W2P0"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W2P0"
                     /gene="sle_46540"
                     /product="Hypothetical Protein sle_46540"
                     /protein_id="CQR64112.1"
                     /transl_table=11
                     /translation="MEHTPRTAWLAEAARTAAEPQGTGNLLRIILIVMVVGCVLTAWFL
                     LRGYKRKDD"
     gene            27138..27302
                     /gene="sle_46550"
     CDS             27138..27302
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VZU4"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VZU4"
                     /gene="sle_46550"
                     /product="Hypothetical Protein SAV"
                     /protein_id="CQR64113.1"
                     /transl_table=11
                     /translation="MSFHSTAAQLVTLAAEGQEHGGNHESLNPYLTGGGAFVILMLLLW
                     ITTRFNRDR"
     gene            27424..28107
                     /gene="sle_46560"
     CDS             27424..28107
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VUA4"
                     /db_xref="InterPro:IPR004821"
                     /db_xref="InterPro:IPR005248"
                     /db_xref="InterPro:IPR014729"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VUA4"
                     /gene="sle_46560"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /product="Probable nicotinate-nucleotide
                     adenylyltransferase"
                     /protein_id="CQR64114.1"
                     /sec_met_domain="CTP_transf_like (E-value: 3.2e-30,
                     bitscore: 103.8, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTGPAHDTVSGAQESPAPGRAAGPGNGPWRTGKRRLGVMGGTFD
                     PIHHGHLVAASEVAAQFHLDEVVFVPTGQPWQKSHRKVSAAEDRYLMTVIATAENPQFS
                     VSRIDIDRGGPTYTVDTLRDLRALNPDTDLFFITGADALAQILTWRDSEELFSLAHFIG
                     VTRPGHHLTDAGLPEGGVSLVEVPALAISSTDCRARVAKGDPVWYLVPDGVVRYIDKRQ
                     LYRGD"
ORIGIN
        1 aggcggtcga ggcccggacc tccgggctcg ccgaccggct gacggcctcc gtgtgggagc
       61 tgcggctgga cggggtggag cccgcggagg ccgcgcgcgc cgtggaggcg ttcaacgcgg
      121 ccggggccgt ggaggtccag cgcctcacca agaacggcgt ccgcaccttc gacgcccgcc
      181 cggccgtcgc gagtctggag agcgtggaaa cgcacggttc gccggctgat aggccgagcg
      241 accggccctg tgcgatactg cggctggttg ttcggcacgt gacgcctgcc gtacgacccg
      301 acgacgtcct gtccggtctc cgcgccgtgg ccgacctggc gccgccggtc cccgcagcgg
      361 tgaccaggct ggcgcagggg ctgttcgatg aagagaccgg cacggtgacc gacccgctcg
      421 cgcccgaccg cgaggcagca gcgaacgagc cccagacggc cgacgcgact gccgccgcga
      481 aggcgccggc gtaaggaagg tcccgcgcag ggacgtacgt cgaagcgccg ccctcgaact
      541 cgggagccac ctgggtcggg cagcgcaccg accagaagac tttcgccagg ccgtgcacaa
      601 aaaggggtac ggaaccggcg agacaggaca cagagagctt ccgagcggcg cccgcgcccc
      661 ggacggcggc atccgcgcag cgcgcgagcc gcggacgtca acggtgatcg acgtgatcga
      721 cgccggacca ggcgcggcgc ccgggagcct gacgggagat acgcccgcat gctcgaaccg
      781 accgagccca ctcagggttc cgaaccgaac actccgagcg acagcctgcc gccgcgtcgt
      841 cggcgccggg ccgcttcccg gccggcgggt ccgccggtcg cctcctccga cacgccggtg
      901 gagacggtga cgccggccat accggccgcc gggagcgacg cactcgccca ggcccaggtc
      961 accgcggacg ccgacgccgt cggtgacgaa gaggagtccg cggcgcagga agccgtggcc
     1021 cagcaggccg cggcccccga cgccgaagag cccgcgcccg cgggacggcg ccgccgccgt
     1081 gtcgtacggc gtgcctccgc gcccgccggg gcccccgcgt cggcggagac ggccgagacc
     1141 gtcctccccg cggcccccgc cgccgaggcc gcacctgccg ccgtcaccgg ggcccccgaa
     1201 gccgccgagg cggtccaggc gcccgaggcg gccgagagtg ccgctccgcg ccgcacccgg
     1261 cgccgtgcca cgcgcacggt gacctcgccc tccgcgaccg ggcagccggc ccagtccgcc
     1321 gatgccgccc agtccgccga ggccgccccg gccgtggagc cggcgcccgc cgccgcaccg
     1381 gccggaaccg ccgacgagac ccctgacacg ccgggcaccc ctgacactgc cgggacgccg
     1441 gccgccgaga gcgccggcga ggaggccgcg gctccgcgcc ggacccggcg ccgcgccacg
     1501 cgccgggtgt ccgcgcccgc cggggcgccc gagacggccg cgtcgtccgc cgaggccccc
     1561 gcgcaggccc ctgtgcaggc ggaggccccg gcgcaggacg aggcccccgc gcaggcggag
     1621 gccgccgcac cggcccggac ccgccgcggc cgcaaggaca ccgccgtgac ccaggccccc
     1681 gaggcccccg ccgccgaggc tcccgagcag gccgcccagg ccgagcaggc cgaccaggcg
     1741 gcccaggccg cgccggccga agagcccgct ccgcgccgca cccggcgccg gaccgtccgc
     1801 aaggcggcca ccggtttcgc cgagcccgcc cggcccgccg gggcctccga ctcggaggcc
     1861 gacgcgccgc ggcgcccggc gcgtcccgcc gtcgccgtgt tccagccgcc ggtgttcgcc
     1921 gagccgaagt tccagacccc ggagcgggcc gccgccgagg cggctgccgt ggccgccgga
     1981 gccgagcgcg tcgaggagac cgaggacacc gaggcggccg aggcgaccga ggagttcacg
     2041 caggagcagg ccaccggctc gcgccgtcgt cgccgtcgcc gcggtgcggc cgccgacgag
     2101 cgcccggagc ccgtggccga cgaggagccc gaggcccccg aggcccggga gaccgaagcg
     2161 ccggaggagc ccgaggccga ggagccggag gagtccgagg acgaggacgc cgagggcgcc
     2221 gagggcgccg agggcgccga ggagggcggc tcgcgccgcc gtcgccgccg gggcggccgt
     2281 cgtcgccgcc ggggcgagtc cggcgagggc gcggacgccg actccgagga gctcgccgcc
     2341 gagcaggccg cccaggacgc cgaggacacc gccgagcagg tggaggagga caccgaggag
     2401 ggtacggacg aggacggggc cgacgagcac gctttcgccg gcaacggcac cagcagcagc
     2461 cgtcgccgcc gtcgccgtcg ccgtcgcgcc ggggacacct ccgccgacac cgagccctcc
     2521 gccgacgacc ccgagcgcac cgtcgtcaag gtccgcgagc cgcgcaagcc cgccgagccg
     2581 tccgacgagg tgcagtccat caagggctcg acccgcctgg aggcgaagaa gcagcgccgc
     2641 cgcgagggcc gcgagcaggg ccgccgccgg gtgccgatca tcaccgaggc cgagttcctg
     2701 gcccgccgcg aggccgtcga gcgggtcatg gtcgtccgcc agcacggcga ccgcacccag
     2761 atcggcgtcc tggaggacgg cgtgctcgtc gagcactacg tcaacaagga gcagtcgacc
     2821 tcgtacgtcg gcaacgtcta cctcggcaag gtgcagaacg tgctgccgtc gatggaggcc
     2881 gccttcatcg acatcggcaa gggccgcaac gccgtgctct acgccggcga ggtcaacttc
     2941 gaggcgctcg gcatgtcggg cgggccgcgc cgtatcgagt ccgccctgaa gtccgggcag
     3001 tccgtgctcg tccaggtgac gaaggacccc atcggccaca agggcgcccg cctcaccagc
     3061 caggtctccc tgcccggccg gtacctggtc tacgtgcccg agggctccat gaccggcatc
     3121 agccgcaagc tgcccgacac cgagcgggcc cggctgaaga ccatcctcaa gaagatcgtc
     3181 cccgaggacg cgggcgtcat cgtgcgcacc gccgccgagg gcgcgagcga ggacgagctg
     3241 cgccgtgacg tcgagcgtct ccaggcgcag tgggaggaga tccagaagaa ggccaagaac
     3301 ggcaacgccc cgacgctgct gtacggcgag ccggacatga cggtccgggt cgtgcgcgac
     3361 atcttcaacg aggacttctc caaggtcatc gtcagcggcg acgacgcgtg gcagaccatc
     3421 cacggctacg tctcgcacgt cgcgccggac ctcgccgagc ggctccagag gtggacctcc
     3481 gaggtcgacg tcttcgccac gtaccggatc gacgagcagc tcgccaaggc cctggaccgc
     3541 aaggtctggc tgcccagcgg cggttcgctg gtgatcgacc ggaccgaggc gatggtcgtc
     3601 atcgacgtca acaccggcaa gttcaccggc cagggcggca acctggagga gacggtcacc
     3661 aggaacaacc tggaggcggc cgaggagatc gtgcgccagc tccggctgcg cgacctcggc
     3721 ggcatcatcg tcatcgactt catcgacatg gtgctggagt ccaaccggga tctggtgctg
     3781 cgccgcctgc tggagtgcct gggccgcgac cgtacgaagc accaggtcgc cgaggtgacc
     3841 tcgctggggc tcgtgcagat gacccgcaag cgggtcggcc agggcctgct ggagtcgttc
     3901 tcggagacct gcgtccactg caacgggcgc ggcgtcatcg tccacctgga ccagccgtcc
     3961 gccgccgcgg gcggcggcaa gcgccgcaag cgggcccggg ccggtgccgg cgagcagccg
     4021 cacgagcacg aggccgtggc cgtcgagacc gccgagacgg cggagcagga ggcggaggcc
     4081 gagtccgagg ccgaggtggc cgccgaggcc gccgagccgg ccgccctccc ggcgcccgac
     4141 ttcgcgccgg acgaggagct gtacagcagc atcgccgagg cggaggccgc ggcgggtcgc
     4201 ggacgcaccc ggcgccggac gagccggcgg gcgtcggctc cggcgggtgc gccccgcggc
     4261 gaggccgcac cggccggcaa gggccgggcg gagaagccgc ggaaggccgc tgccgagcag
     4321 ccgcaggacg agaaggccgt cgtggcggcg tcggcggagc agggcgcggg ggcggaggtg
     4381 cccacggccc aggacgtcac ggccgagcag gaggccgcgc gtccggtgcg ccaggagtcg
     4441 gccgccgagg cgctggccga gcccgccgcc gtcgaggacg ccgtcgtcgc ggcgccggcc
     4501 cccgaggctc cggccgccga ggcagcggtc accgaggagg aggccgcgcc caagggccgc
     4561 acccgtcgcc gggcgacccg ccgggcgtcc gcgcccgccg ggtccccggc cggggcggag
     4621 gcggccgtgg tgacggtccc cgagtccgca ccggcggcgc ccgaggcggc gccgcaggcc
     4681 gaggaggccg ccccggcggc ttcggcggag cagccggaga ccgccgccga gccggccgcg
     4741 ccggcccgtc cgcggcgccg cgccgtgcgg aaggccgccg cgccgaccgc gcccgcggag
     4801 gccgccgtcg tggtcctccc ggccgccacc gagccggccg ccgagccgga agccccggcc
     4861 caggaggctc cggttcagga ggccgcggct tcggaggctc ccgccgccga gccggccgcc
     4921 gagggcccgg aagcagccga ggccgcggct tcggaggctc ccgccgccga gccggccgcc
     4981 gagggcccgg aagcagccga ggccgccgaa gaggccgtcg cggccaagaa gacggcgcgc
     5041 aagacggcca agaaggccac ggcgaagaag gcggccacga agaagaccgc ggccaccaag
     5101 aagaccgcgg ccaccaaggc ggcgacggcc aagaagacgg ccgcgaagaa gacgaccgcc
     5161 aagaaggcgg cggccaagaa gaccgccacc aagacggcgg ccaggaagac ggccgccaag
     5221 aagaccgcgg cggccgagca gacggctccg tccgtctcgg cctccaccga cgaggtctga
     5281 cccgaccagg gtccaccgac gtggggtcct gcccggaggc gggcagggcc ccacgtcgtc
     5341 tcgtccgccc cggtgttccg acgcccggaa cgccgctgac ggcccgcaag caaggagaga
     5401 aacacgatga ttggcctcat actcgcggcc ggtgccggac ggcgcctgcg cccctacacc
     5461 gacaccctgc ccaaggcgct ggtgccggtg gggcccgagg gcgccgagga cagcctgacc
     5521 gtgctcgacc tgacgctcgg caacttcgcg gaggtcgggt tgaccgaggc cgcgatcatc
     5581 gtcggttacc gcaaggaggc ggtgtacgcg cgcaaggagg cgctggaggc gaagtacggc
     5641 ctgaagctca ccctgatcga caacgacaag gccgaggagt ggaacaacgc ctactccctg
     5701 tggtgcggcc gggaggcgct gaaggacggc gtgatcctcg ccaacggcga cacggtgcac
     5761 ccggtgtcgg tggagaagac gctgctggcc gcccgcggtg acggcaagaa gatcatcctg
     5821 gcgctggaca cggtgaagca gctcgccgag gaggagatga aggtcgtcgt cgacccggcc
     5881 aagggggtgc ggcggatcac caagctgatg gacccggcgg aggcgaccgg tgagtacatc
     5941 ggtgtgacgc tgatcgaggg ggaggccgcc gccgagctgg ccgacgccct gaaggcgacc
     6001 ttcgagcggg acccgcagct ctactacgag gacggctacc aggagctggt cgaccgcggc
     6061 ttcacggtgg acgtggcgcc gatcggcgat gtgcggtggg tcgagatcga caaccacgac
     6121 gacctcgcca agggccggga gatcgcgtgc cgctactgac ccggctcatc ccggcgccgg
     6181 tcgtcgtcga catccgcgcg ggcgccctcg acgacctgac gagcgtcctc gccgaccagc
     6241 ggatctccca gtcgggacgg ctcgccgtcg cggtcagcgg gggttcgggg gcgcggctgc
     6301 gcgagcggct ggcgccggcc ctgccggggg ccgagtggtt cgaggtcggc ggcgggacca
     6361 tcgacgacgc ggtgcggctg gccgacgcga tgaagggcgg ccgctacgac gcggtcgtcg
     6421 ggctcggcgg cggcaaggtc atcgactgcg ccaagtactc cgcggcgcgc gtgggcctgc
     6481 ccatggtcgc cgtggccacc aacctctccc acgacggcat ctgctcgccg gtgtcgatcc
     6541 tggacaacga cgccggccgc ggttcgtacg gcgtgcccac gcccatcgcg atcctggtcg
     6601 acctcgcggt gatccgcgag gcgccgatcc gcttcgtgcg gtccggcatc ggcgacgccg
     6661 tctccaacat ctccgccgtc gccgactggg agctggcgca ccgggtcaac ggcgagaagg
     6721 tcgacggcct ggccgccgcg atggcccggc aggccggcga ggccgtgctg cgccaccccg
     6781 gcggctgcgg cgacgacggg ttcctgaccg tgctgaccga gggcctggtg ctgtcgggca
     6841 tcgccatgtc gatcgcgggg cacacccgcc cctcgtccgg ggcctgccac gagatcagcc
     6901 acgcgctcga cctgctctac cccaggcggg cggcgagcca cggcgagcag gtggggctcg
     6961 gcgccgcctt cgcgatgcat ctgcggggcg accacgaggg ctcccggctg atggccggcg
     7021 tgctgcggcg gcacggcctg ccggtcctcg ccgaggagat cggcttcgac gacgacgagt
     7081 tcgtccgggc cgtggagttc gccccgcaga cccgtccggg ccggtacacc atcctggagc
     7141 acctggagct gtcgccggcg cgcatccgcg aggcgtacgc cgactacgcc gcgtcggtcg
     7201 acgactgagc cgcgcgggcc cggtttgacc cctgtgggga gggccccgta accttgaccg
     7261 tcggcgtgtc cactgacatg ccacatcccc gtaaacctct tcctcccgga cacagggctg
     7321 gccgggagag gccgtccgtc aagccggacg gctggcctgc gggggtgccg ttccccgagc
     7381 gtagagagtg agttccgcgt gtacgcgatc gtgcgcagcg gtggtcgtca gcacaaggtt
     7441 gctgtcggcg acatcgtcga ggttgacaag atttccaccg ccaaggtcgg cgacacggtc
     7501 gagctctcga ccctgctcgt tgtcgacggc gactccgtga ccagcgaccc gtgggtgctg
     7561 gccggtatca aggtccaggc cgaggtcgtg gaccaccaca agggccagaa gatcgacatt
     7621 ctgcgctaca agaacaagac cggctaccgt cgtcgtcagg gccaccgcca gcagtacacg
     7681 gcgatcaagg tcactgagat ccccacggct gcgaagtaag ggactgagaa cagatggcac
     7741 acaagaaggg cgcatcgtcc acccggaacg gtcgcgactc caacgcccag cggctcggcg
     7801 tgaagcgctt cggcggtcag gtcgtcaacg cgggtgagat cctggtccgc cagcgtggca
     7861 cgcacttcca cccgggctcc ggcgtcggcc gtggcggcga cgacacgctg ttcgccctgc
     7921 aggccggttc ggtgcagttc ggcacccacc gtggccgcaa ggtcgtgaac atcgtcccgg
     7981 tcgcctgaat cgcctgacgg gcgtttcgac cgagcgtttc gagaggcgga cctcacttcc
     8041 cgtacgggaa gcgggtccgc ctttcgcgcg tttcacctac gcaccgcttt tcacgcgcac
     8101 cacagcgata cgcgcaccac actgaagaga ctttcccgca cttcccccgg ttccggccgg
     8161 ggcaccccca ggaggcaccc caccatgacc accttcgtgg accgcgtcga actccatgtc
     8221 gccgcgggta acggaggcca cggctgtgcc tccgtccacc gtgagaagtt caagccgctg
     8281 ggcggcccgg acggcggcaa cggcggccgc ggcggcgatg tgatcctcac cgtcgaccag
     8341 tcggtgacga cgctgctgga gtaccaccac tccccgcacc gcaaggccac caacggcaag
     8401 cccggcgagg gcggccaccg ctccggcaag gacggccagg acctcgttct ggcggtcccg
     8461 gacggcaccg tggtcctcga caaggcgggc aacgtcctcg ccgacctggt cggccacggc
     8521 acctcgtacg tcgccgcgca gggcggccgg ggcggcctgg gcaacgcggc gctggcctcc
     8581 gcgcggcgca aggcgcccgg cttcgcgctg ctcggcgagc ccggcgacgt gtgcgagatc
     8641 gtgctggagc tgaagaccgt cgccgacgtg gcgctggtgg gctacccgag cgccggcaag
     8701 tcgtcgctga tctccgtgct cagcgccgcc aagccgaaga tcgccgacta tccgttcacg
     8761 accctggtgc cgaacctggg cgtggtgacg gccggctcga ccgtctacac gatcgccgac
     8821 gtccccggcc tcatccccgg cgccagccag ggcaaaggcc tgggcctgga gttcctgcgg
     8881 cacgtggagc ggtgcagcgt gctggtgcac gtgctggaca cggccacgct ggagtccgac
     8941 cgggaccccg tctccgacct cgacgtgatc gaggaggagc tgcggcagta cggcggcctc
     9001 gacaaccgcc cgcggctcgt cgtcctgaac aagatcgacg taccggacgg ccgggacctg
     9061 gccgagatgg tgcgcccgga cctccaggcg cgcgggtacc gcgtcttcga ggtgtcggcg
     9121 gtcgcgcaca ccggcctgaa ggagctctcc ttcgcgctgg ccgagctggt ggccgccgcg
     9181 cgtgccgccc ggccgaagga agaggcgacc cggatcgtga tccggcccaa ggcggtcgac
     9241 gacgcgggct tcaccgtcac gcgcgaggag gacggcctgt tccgggtgcg cggcgagaag
     9301 ccggagcgct gggtgcggca gaccgacttc aacaacgacg aggccgtggg ctacctcgcc
     9361 gaccggctca accgcctcgg tgtcgaggag gagctgatga aggccggcgc ccgcgccggc
     9421 gacggcgtcg ccatcggccc cgaggagaac gcggtcgtct tcgactggga gccgtcggtg
     9481 atggcgggtg ccgagatgct cggccggcgc ggcgaggacc accgtctgga ggctccccgc
     9541 ccggccgccc agcgacgccg ggaccggcag gccgaacggg acgacgcgca gcgggagttc
     9601 gacgacttcg agccgttcta ggcgagggcg gttcccgccc cgcgcccgtc cgggcgccgt
     9661 ccgcgccgtc cgcgcggggc gggtgccggg cacaggctgt tcgccgtacg tccggccggt
     9721 ggccggacgt acggcgtccg ggccgtggtc gcgcgggacg ggcccgggtg ccgcggccgg
     9781 tgaccgctgt ggctcgcgcg tgtctcaatc gtgaccgctc ggtgaacaac gttgtgcggt
     9841 ccgtccacgt ctaatgtgcg gggccgctcc ctgcccggcc gggacacgtt ccgccggtgc
     9901 ggtggggaac ccgggacaca ggccggccgg cacgacgacc ggtgctcgga ccacggccaa
     9961 ggacggcgtc cgcacgcggc gccctggatg gggactcact gtgaagattg cattcctggt
    10021 ccgcgacctc tgccacatgg ggggcgtggt gagcgcgacc cagaatctcg ccggcgcgct
    10081 cgccgaccgg cacgaggtgg agatcgtggc gttgcgcaag gtgcgcgacg agtcgtactt
    10141 ccccctcgac cccagggttt cggtacgggt gctcagcgat ctgcgcccgc actcgccggt
    10201 ctccgacctg gacgacccgc tggtggagaa gtggccgctg gtctacccgc ccaacaccgg
    10261 tgcgaagaag ccggtcgtca gccgtctggc cgagcgccgg ctgctggagt acctggcgac
    10321 caccgacgcc gacgtcgtgg tcagctccag cccgcgcaac accatcatgc tggctcaggc
    10381 cccgggcacc tacctcaagg tcgcccagga gcactccatg ccgtccatct acgccaagga
    10441 catcaaggag cggctcttcc cggcctatct gtccctggac gccctgacgg cgctcacccc
    10501 cgaggaggtc gagagcatcg ggcggcaggt gccggcggtg cgggaccggc tggcggtcat
    10561 gccgaactgc gtgcccgcct ccccgatccg ctccaagggc accaacaagg tcgtcgtctg
    10621 cgccggccac ctcaccgaca acaagaacca cgccctgctg gtcgaggcgt tcgccaaggt
    10681 gcacgcccag gcgcccgact ggacgctgcg gatctacggc agcggcgccg agaaggcccg
    10741 gctgcgggcc cgtatcgagg aactgggcct gtccaacagc atcctgctga tggggcagac
    10801 cgccccggtc acgccggagt tcggcaaggg gtcgatcttc gtcctgccgt ccaagcggga
    10861 ggcgttcggg aacgtcatcg tggaggccat ggcggccggg ctgcccgtgg tcagcaccga
    10921 cgccgaccac ggcccgcgca acatcctgac ccccggcgag gacggactgc tcgtcccgcg
    10981 cggtgacgtg gaggagatgg cccgggcgat cctgcggctg gtccaggacg acgagctgcg
    11041 gcagaagatg gccgccaacg ccgtgcgcgg cgccgagcgc ttccacgaga ccgccagccg
    11101 ggagcggttc gaggcgatcc tggagcgggc gctcgcccgc aaggcgctgc cccggcacgc
    11161 caccgcccgg gtcgacgacc ggggcagcgt gcacatcgag gtcggcccgc tgcccgagcg
    11221 ggcccggggc gccgagctgg tgctgcgccg cagcggcaag aacggcgagg agcaccgctt
    11281 cccgctctcc gactccggcg aggcgctcgt cgcctgggac gccgggctgc cgcacggcac
    11341 ctgggaggcg gcgctggcct cgccctcggg cggggaggtg ccgctgacca ccgacggcta
    11401 cggctgcgac acccgtgacc tgctcgccgt ggagctgccc cggccgcacg gccacccgct
    11461 cgcgctgctg ctgccgcacc ggcacgacga cggccggctg cgggtgcgca gcgccctgcg
    11521 cgcggtgcac gccgaggtcg gcccggtccg cgtggacgac caggccgtcc ggctgcgggc
    11581 ggagctgtgg ggcgcgacgc tgggccgggg cgcggtggtg gaggccgtgc accggcgcga
    11641 caaggagcgg gtgctcacct tcgaggcgcg cgacgccggg gacggcgcct tcgaggcggt
    11701 cgtcgactgc gcggccctcg cgcgggagca cggcgaggag gacggcaagg aggccatctg
    11761 ggacttctgg atccgtccgg aggaaggggc gccgcgcgcc gcgctggcga agctggccac
    11821 cgacgtgctc aagccgatcg acgtgttcac cttcccccgc ccggtgctca ccagcggcgc
    11881 cgtggcacgg ccgtcggtgg tgcgccgcgc cgcccgccgg gcccggcgca gcctgggcgc
    11941 gacgccggcc gccctgccgc ggccggtccg gaccgagctg cggccgtact acacggcgct
    12001 gagccagttc gcggtgaaga ccgtacggct gtgacccacc gccgcggcgc ggacggcgcc
    12061 gcggcacccc acgacgacgg gccgggcccc ggaggaaacc tcctccgggg cccggcccgt
    12121 tccgttcagc gccgcggggc ggtcacagct cccggctctg ctccagcatc cggtccacga
    12181 cccgcgtcga ggcgttgccg tcgtccaggt cgcagaacag gtggtggaag cgctcgaagc
    12241 gctcctggta ctcggccgac acctggtcga tgtcgcgcag cgcgtcgacc agttccttgg
    12301 acgtggcgat cagcgggccg ggcgagtcct gctcgaagtc gaagtagaac ccgcgcagcg
    12361 tgtcccggta gtgctccagg tcgtaggtga agaacagcat cggccgccgc aggtgggcgt
    12421 agtcgaacat gaccgacgag tagtccgtga tcatgacgtc ggcggcgagg tagaggtccg
    12481 cgatgtccgg gtactccgac acgtcccaca cgaagccgtt gccggcgccg ggcaccgcgt
    12541 cgaccacgtt ggagtggcgg cggatgagca gcacgtggtc gtcgccgagc cgccgctgcg
    12601 cgtcctccag gtcgatccgc agatcgaaca ggtactggcc ggcgctgtgc gacaggtcgt
    12661 cccgccaggt cggcgcgtac aggacgacct tcttcccctc gggcaggccg agctgcttct
    12721 tcacccgctc ggcgatgcgg tccttgtcgg gggagtacag gtagtcgttg cgcgggtagc
    12781 ccgcctccag gatctcgccg tcgtaggaga aggcgcgctt gaggatgggc gtgctgaagc
    12841 ggttggagga gaccaccagg ctccactgct tcgcctccag cgccagcttc tcctggtagc
    12901 ggcggtcgaa gtgcagcgtg tcgatgtcgt ggccgatctt cttcagcatc gtgccgtgcc
    12961 aggtctgcac gatgacctgg cccgggcgcc gctcgatcca gtccggcagg tggccgttgg
    13021 tgacgatgta gcggctggtg gcgagcgcct cgtaccactc ggtgccccac atccgcaccg
    13081 gctcgacgcc ctcgggcagg atgacctgcc cgtcgcggac cgcccacagg tgcttgaggt
    13141 ccgagccgcg gcggaccagc tcctggtaca tcgccttcgg gctgtcggag aactgcttgc
    13201 cgttgtagct gaggtagaag acctggtcgc gcaagggctg ccggcgcagg ggctggtaca
    13261 gatcgcggcg gagctgcttc tgccggaacg ggccgcgctc caggtcgctc agctccgagc
    13321 ggcagttgag ctgcgggaag tcggcccagc ggttctccag ccagtagcgt cgcccgttca
    13381 gttcggcgcg cagcgggaac tggtccgccg ccagccggtc ggtgacgaag ggcacgtcgg
    13441 gcgcgccgtc ctccgggcgc agccacaggt tccagcggcc cgcgcgcagc ggcacgttgc
    13501 ccccgccgcc gagggtcgac gggtcgaagg cgacctcgaa gcggccgtcc tcggaccagc
    13561 gggcctcgac gaagcgctcc tcgaagcggt tgcgcggctt gagcaggaac cgggcgccgg
    13621 tgagccgcgg gtcggtgtgc gcggcgatgg tgatgcggcc gtcctcgacg ccgacccggt
    13681 cgatcgtggc gcggcgggtg cggccggcga acttcaggta gccggtgtgg cccgcgacga
    13741 tggccagctc gcacagctcg gcccgctcgc ccagcgaggc gggcaggttg aagcgggcgt
    13801 cgggcaggcc ctcctggagc acggtgctga actggcgctc ggcgccctgc gggtcccggg
    13861 cgatcagcgc ggtggaccag gtgcggttct ccggctgcgc cttggcgtcg acgccgtcgt
    13921 ggaacaccag cgccacgtcg gccaccggga cctccaccga gaaccggtgg gtgccgccct
    13981 cgtcggtcac ggtcaccggg tactcgtgga cgtcggcgcc cttctggttg cgcacccgca
    14041 gcaccacgtt ctcgccggcg gcgaggggca cccgtatctc accggtgacc acgatccggt
    14101 cgccctccac ggtgcgcccg gtgatcagcg cccggacccg ctcgatgcgg atcttgagcg
    14161 cgccgcgctc gacggagggc agcagccgga agtcggggct cagccagtgg tacggcggga
    14221 agttgcaggc ggcgccgccg ctggactgca cggcggcgcg gcgcaccagg ccggaggcgt
    14281 acaggccgag gcccacgtgc cacaggccct cctgccactc gccgcccttg cgcagccgcg
    14341 ccgggtcgat ggtgacctcc cagccggccc agtcgtagtt gtagcggtcc tggccggagt
    14401 tggtggtgca ctcgggacgg tggatgttgc gggcgggcag caggatgcgg cggcgggact
    14461 tgtccttgcg cagctgcagg accttcaccg aggagtgctt cgaggccagg tcgatcttgt
    14521 cgatccaggc gttgccggac agtacgagct tgccctcgga ccaggtcacc tcctggagcg
    14581 gggcgcgcat ccgcaggtcc tggtcgatgc gcagcgcctt gcgcgggaag tccaggtcgg
    14641 cgtcggccag cgaggggaag gaggcgtact tgcggaccag gccgctgacc tcgacggcct
    14701 ccttgcgccg ctggccggcg agcagggtga tcagctcgtc cagcttgtgc ttgcgcacca
    14761 gcagccactg cacgcgaagc tgggcgggga gcgccatgac gaccttgggg tcgatgcggt
    14821 ccaggaagcg gttggccgag cgcaggaact cggcgcggta ctcctcgtcg ccgtcgggca
    14881 ccacgttgag gaacagccgc aggtcgtcct tgaggacgcg ggtgtcgtac tcctccttga
    14941 gccgggcgaa catctcgccg ggctgctcgg ccaggaaggc gctgatctcc agcacggagg
    15001 tgacacggtc gcggacaccg gccgggtcgg tgcggcgctg ggtgatggag ggagcggact
    15061 cgccctcgcg cagccgccag tagtagcagg gctcggagat gacgtcgacg gcgtcggcga
    15121 ggtagtgggc ccgcatcgtg acgggcgtgt cctcgtacag gcggccctcg gggaaggcga
    15181 agccgtgctt ctcccagaag gtgcggcgga agaccttgtt gcaggcgatc cggtcggcga
    15241 cgagcttgcc gtagcgggag atgtgggtgg cgcggcgggc ctcgccggcg agcatcctca
    15301 gcaggggcac ctgccaggtc ttctcgccct tgaggtggaa gacgttgccg gtggcgaagt
    15361 ccgagccgga ctcgtccagg ctgctcacca tcagccggta ggcgtccggc gggatcaggt
    15421 cgtcgctgtc gacgaaggtg acgtactccg cctgcgggga catgtgggcg atgcccgtgt
    15481 tgcgggcggc gcccagaccg ccgttctcct tgcgtatcag tttgaagcgc gggtcgcgct
    15541 cggcgtacgc ggcggctatg gaggcggagt cgtcgggtga accgtcgtcc accatcagga
    15601 cctcgaagtc gcggaaggtc tgggctgcca gcgagtccag gcaggccggc agatagcgct
    15661 ccacgtcgta gatggggacg atgacactga gccgaggggc catggcttgg tggtctcctt
    15721 tcggggtcag gcccgctcga ccggttcgag cgcctgggcg ggggtcgggg cgtgggagcg
    15781 ttcgtcgaag gggacgaacg gcagcggggt ctggtcaccg aggaagacgc gccgaacgac
    15841 gcgttcggct gcgtgcccgt cgtcgaattc gcagaaacgc ctgcggaagg cgtcccgccg
    15901 cccggccgcg tcccggctgt cgtagtcacc cgacccgagc agcctgatca gctccgcctg
    15961 cgaggtggcc accgcgccgg gcggctcctg aaggaggtcg aagtaggtgc cgcgcacggc
    16021 ggagtagatg tcccagtcgg gcgcgtagac gatgatcggg cggtccagga cggcgtagtc
    16081 gaacatcgcc gaggagtagt cggtgatcag cgcgtcggcg gcgaggtaga gctcctccac
    16141 gcgcgggtgc ccggagacgt cgacgatccg gccgctgcgg cgcagttcgg cgatgtgcgg
    16201 ggagctgccg tagaagtagt ggccgcgcag cagcagggtg acgtcgggcc cgagttcctc
    16261 ggccagccgg gccaggtcca ggctcggggt gaagccgggc tggtactcgc ggtgggtcgg
    16321 catgtacagg aaggccttgg cgccgtcggc gagcccgagg gccgcacggg cccggcgcac
    16381 ctcctcggcg ccggcgttga ccaggacgtc gttgcgcggg tagccggtct ccagcgagac
    16441 gtaggagcag gggtagaccc gctcccatat cgcggtcgag aagcggttgg agctgatgct
    16501 gtagtcccac cggtcgcacc gctcgagcag cttctcgaag ttcatgtcgg tggaggccgg
    16561 gtacttctgc tggtccaggc ccatcgtctt cagcggcgtg ccgtggtggg tctgcagatg
    16621 tatctgcccc tcgcgcttga ccacggcgtc ggcgaagttg acgttgttga ccaggtactt
    16681 ggcgcgggcc agggccgtcc agtacgcgcg tgagcccacg cggacgtact ccacgccctt
    16741 gggcacctgg tccaccgcgt cggggcggat ggcccacacg cggcgcaggt gcggggcgag
    16801 gcgggccagt tcggcgtcga tggccgcggg gttgcaggag acgctgcggc tccagtaggc
    16861 ggagaacagc accaggttct cgtccagcgg cagccggagc tgcgactggt agtggacgcc
    16921 catcgcgctg cgcttggagc ggttgagggc gtcgcgggtg cgcttcctga ccgtccggcg
    16981 cagcttcacc gcggtggagg cgctcatcat ggccgcgtac gcgtcgcgct ccagcatcgc
    17041 gtacttgtgg ccgcgcccgc cggccggctt ctggaagccc ttgggcagcc gggcccggta
    17101 gtcggcggag gcgcggtgga agaactcggc gcgcgcctcc cgcggcaggc ggccggggcg
    17161 ctccagcacg gtgaggtagt ggtcgaccat cttgcggaac aacgggccgc gccaccggtc
    17221 gagttcctcg tgcgcgtcga ggaagtcgaa gacgcggcgg tactggtcga agacgtcgaa
    17281 gtgcttgcgg ctgaccgtct tgaggatgtt gccgccctcg cggcgctggc ggtacaggac
    17341 gcagacgcgg tccagtacgg cgatccgctc ggcgctgatc agcgagcaga acgtccaggg
    17401 ggcgtcctcg tagtacccgg gcgggaaggt gaggccggtg cgggtgatga agtcgcggcg
    17461 gtacgccttg ttccagacga tctggagcag gtccagcagt tgcgggcgct cggcgaggcg
    17521 gaacacctcc ggcccgtcgc tcttgagcag gtccgcccgc tggttggggc ggacctggcc
    17581 gtcccagtag gtgcgggcgt agtcgaagac gagtatctcg gggtcgccgg tggccgccag
    17641 gcgctcggat atcgcggtca gggcgccgtc ggacagcgtg tcgtcgctgt ccaggaacag
    17701 cacgtattca ccctgggcct tttccagtcc cgcgtttctc gcccgtccca gcccgacgtt
    17761 ctccgtgagg tgaatcacat gaatccgcgc gtcccgccgc gcgtactcgt cgagaatggc
    17821 ccctgacccg tccggcgagc agtcgtcgac ggcgatgatc tcgaagtccg tgtagtcctg
    17881 gccgagcacg gagtcaaggc actcgggcag gtagccctgc accttgtaca cagggacgac
    17941 gagagagagt ttgggcatcc ttacaacctg ttccgagaac tgaccacggg gcgctggctg
    18001 gggccggaac gcgctccgag cgcggtggac cgggagcgcg ccgccgcatc agcgtaaagg
    18061 attcacatga agtttccgtg ggcacggtag cgggtccgcc acgggccgga tgtgaccgga
    18121 acacccggaa aaaacccgga aatacgtgag tgaatgagcc gctccgcagg gagtggagaa
    18181 cttgctcacg ttgagtcagt aacatcccgc tttaatggct tttgtcccat ctgtccgact
    18241 cgattttccg gagcccacgg acgagtctgc acccagtgac aacgacctgg gaggcatgag
    18301 gatgagctgg ctggtcacgg gcggagccgg gtacatcggc gcacacgtgg tgcgtgccat
    18361 ggcggcgggc ggtgaacgcg tggtcgtcta cgacgacctg tccaccggca gcgccgaccg
    18421 ggtgcccgac ggcgtgccgc tggtcgtcgg cagcgtcctg gacgcctccc tcctggcgcg
    18481 ggcgattcgt gaccatgctg tgacaggcgt ggtccacatc gccgccaaga agcaggtggg
    18541 ggagtccgtg gagcagccgc tccgctatta ccgggagaat gtcaccggtc tgcggaccct
    18601 gctcgaggtc atgacggacg cgggcgtcgg caagctcgtc ttctcctcct ccgccgcggt
    18661 gtacggcatg cccgatgtgg agctcgtcac ggaggacacc ccctgtgcgc cgatgagccc
    18721 ctacggcgag accaagctgg tcggcgagtg gctgatcgcc gccaccgccc gggcccacgg
    18781 catccgggcc gcctcgctgc gctacttcaa cgtggcgggc gccgccgaac ccgcgctggc
    18841 cgacgccggt gtcttcaacc tcatccccat ggtcttcgag cgcctggagg cgggcgaggc
    18901 cccccgcatc ttcggtgacg actacgccac ccccgacggt acctgcgtcc gcgactacat
    18961 ccacgtcgag gacatcgcct ccgcccacct cgcggcggcc cggcgtctgg gcgaggccgc
    19021 cgagggcacc aacctcgtcc tcaacatcgg gcgcggcgag ggcagttccg tccgcgagat
    19081 ggtcgaccgc attctcaaga tcaccggcca tgagcacctc accccggcgg tggcggagcg
    19141 caggcccggc gacccggcgc gggtggtcgc ctccgccgac cgcatccggc gcgagctcga
    19201 ctggtcggcc caccacgacc tggacgacat gatccggtcg gcctggcagg gctggcgcca
    19261 cctgcgcggc tgagccggac cggccgtagc gccgcccggc cgccccgccg gcgtccggca
    19321 cctgaaacgg gcgcgcggcc cgccgcccgc ctcgcgtaga ttgcgagacg ggcgacagga
    19381 ccgccgacga ccgtggacga ggggaaagag cacaggtggc aggggcaagg caggctgtgg
    19441 gcgaggcccg caggatcgtc gtcaaggtcg ggtcctcctc gctgaccacc gccgagggcg
    19501 ggctcgacgc cgaccgggtc gacgcgctcg tcgacgtact ggcgaaggtg cgcagcgggg
    19561 gagagcggga gatcgtcctc gtctcctccg gcgccatcgc cgccggcctc gccccgctgg
    19621 gcctgcgccg ccgcccccgg gacctggccc gccagcaggc cgccgccagc gtcggccagg
    19681 gcctgctcgt ggcccgctac accgcctcct tcgcccgcta cggcgtccgg gtcggccagg
    19741 tgctgctcac cagcgacgac atgagccgcc gcgcgcacca ccgcaacgcc tcgcgcaccc
    19801 tggacaagct gctcgccatg ggcgccttcc cgatcgtcaa cgagaacgac accgtcgcca
    19861 ccgacgagat ccgcttcggg gacaacgacc gcctcgccgc cctcgtcgcc cacctggtcc
    19921 acgccgacct gctggtgctg ctctccgacg tggacggcgt ctacgacggc gaccccggca
    19981 ggccgggcac cgcccggatc gccgaggtgc ggcggcccga ggacctcgcg cacgtcgaga
    20041 tcggcagcgc cggcaaggcc ggggtcggca ccggcggcat ggtcaccaag gtcgaggcgg
    20101 cccgcatcgc cgccgccgcc ggcatccccg tggtgctgac cagcgcggtc cacgcggccg
    20161 acgccctgac cggccaggac accggcacct acttccaccc caccggcaag cggtccgccg
    20221 accggttgct gtggctccag cacgcctcca ccccgcaggg cgccctcacc ctcgacgacg
    20281 gggcggtgcg cgcggtcgtc gagggccgca aatcgctgct gccggcgggc atcgcggcgg
    20341 tggagggcga gttcgtcgcc ggggaccccg tggagctgcg ggacggcgag gggcgcgcgg
    20401 tggcgcgggg gctggtcagc ttcgacgcca aggagatccc ccggctgatc ggccgctcga
    20461 cgcgggagct ggcccgggaa ctcggacccg cgtacgaacg tgaggtcgta cacagggacg
    20521 atttggtgat tctgcacccg taatgggtcg aaacttcccc gcaccggtgg tggacgttcc
    20581 gcaaaaccgc cccgcgatca tgcgccgcct gctcaacttt gttccggggg cgggtccgcg
    20641 cggctccgtc ccggcaacca gcccgtgacc ctcgggtcgc cctgtgcacg aaggaggccg
    20701 tcgtgagacg agtgcgcccg ggggcggcga cgtcccgcgg tggtgctgcc tcccgcgcgg
    20761 ccggggagga gcgcgccctg accagcgtgg cggcggggga gcggcacgag cgcgaggggc
    20821 ccgccgacgc cccgcgcctg tggcacgtca ccctgagcgt ctccggcgca cgcgccccgc
    20881 tgccggaggt gcggcgcgcc ctggaacagc tcgcgcacga ccatcccttc ctcctgacca
    20941 gcagatacgc cgacgaccac gccgagatcc gctactggga ggaggcccgc gacctgcacg
    21001 acgcggccgc cgtcgcgctg cgcctgtggg gcgagcaccg ccagaccgcg ggcctgccgc
    21061 cctgggagat cgtcggcctg gaggtcatcg accgcgccac ctaccaccag cgcatcgccg
    21121 cggggtacgg gccggccccg gcgacccctg tcggggttca ccccttttga ggccgtctcg
    21181 cgctgtggga cgaccgctgg acgggcccgg cgcgcgcact acgcttccct catgaccacg
    21241 ctctcgccgt acgactcgat gaccccggtc acccaggccg cctaccgtgc caaggccgcc
    21301 gccgccgacc tcgccccgct gccgcgggcc gtgaaggacg acgcgctgct cgccatcgcg
    21361 gacgcgctgg aggtccgcac gagcgagatc gtcgaggcca acgcccagga cgtggccaag
    21421 gcccgcgagg ccggcaccag cgaggccatc gtcgaccggc tcaccctgac cccggagcgg
    21481 gtgcgggcca tcgcctccga cgtgcgggac gtcgtcgcgc tgcccgaccc ggtcggcgag
    21541 gtcgtccgcg gctcgaccct gcccaacggc atcgacctgc gccaggtccg cgtcccgctc
    21601 ggcgtggtcg gcatcatcta cgaggggcgg cccaacgtca cggtggacgc cgccgccctg
    21661 tgcctgaagt ccggcaacgc cgtcctgctg cgcggctcct cctcggcgta ccggtcgaac
    21721 accgccctgg tccgggtgat ccgcgacgcc gtgggcgggg ccggcctgcc cgccgacgcc
    21781 gtgcagctcg tccccggcga gagccgggag agcgtccgcg agctgatgcg cgcccgcggc
    21841 ctggtcgacg tgctcatccc gcgcggcggc gcctcactga tcaacaccgt cgtccaggag
    21901 tccgtcgtcc ccgtcatcga gaccggcacc ggcaactgcc acgtctacgt cgacgcggcg
    21961 gccgacctcg acaccgcgat cgacatcctg atcaactcca aggcccagcg ggtcagcgtg
    22021 tgcaacgccg ccgagaccct cctcgtccac caggacatcg cccccgagtt cctgccccgc
    22081 gccctggacg ccctggccga cgccggggtc accgtgcacg ccgacgagcg cgtgatggcg
    22141 tacgccaagg actcccgggc gacggtggtc gaggccaccg cggaggactg ggagacggag
    22201 tacctgtcgt acgacatcgc cgccgcggtc gtcgactccc tcgacaaggc cgtcgagcac
    22261 atccggctgt ggacctccgg gcacaccgag gcgatcgtca ccacctccca gcaggccgcc
    22321 cgccgcttca cccagcgggt cgactccacc accgtcgccg tgaacgcctc cacccgcttc
    22381 accgacggcg gccagttcgg cttcggcgcc gagatcggca tctccaccca gaagctgcac
    22441 gcccgcgggc cgatgggcct gccggagctg accagcacca agtacatcgt caccggcgac
    22501 gggcacatcc ggcgctgagc ggcggccggc ggggcggcgt tccctctcac ccggcgtcgg
    22561 tgcgcggaga cggagacggg cgggtggcag agcctccgcc tgtgaggaga cgggggacgc
    22621 gatgcgaggg tggcgggacc gcggtcggcg gctggcggtg gtctccgggc tgttcgcggt
    22681 gctggtcgcg ccggcaacgg ctccggcggc ggcggtgccg gcggggcacc ccgtggggcg
    22741 atccgcggcg cgggccggtg ccgggccgga cgagcccgac gtcgccgtgg tcgtcaccgc
    22801 cggcaccggg cgtaccgagg cgtggcgtgc cggggaactc gccttcgacc ggctgcgcgg
    22861 tctgctcgac ccggcgtaca gcggtacgga gcgggtgccc gaggagtggg ccgaggggcg
    22921 gtatccgcgg gtgcggttca ccgtgctctg ggggctgacc ggcgtcgggg gctggccgca
    22981 gacgcggcgg gcacccggcg gggacgtggc gatgctgcgc caggaccagt tgttcctggc
    23041 accggacggc accccgtggg tgcggaccga tccggcgccg gacctgcccg acgacgacat
    23101 ccgctggcac cgcgtgccac gcggggagta cgaccggctg gcgggcgtgg gcttcatggg
    23161 gctcggcggc gcacaacccg ccgtgggcga ggccggtgcg ggggagggcg gggcgcggga
    23221 gggcgtgtgg tgggcggccg gggggctcgc cctcggggtc gccgggacgc tgctgacacg
    23281 tcgcgcggcg gcccggcgcg gtgcccggcc gccgcgggac gagcctcgtc aggagctgat
    23341 cgacgggtga gcgcccggct gggccggccc ggtctgtcac ggatacgggg aaagccggcc
    23401 ggcgtccggg acgtgcgcgg tttcgcaggg gagccggact cggtggtgcc gggctcggcg
    23461 gccgtccgga cgtgcccggc ccggtctcct gccggtcgca ggaggcgggt cgggcggtgc
    23521 tcacgaccgt tggtctccgc gcgggccgcg gatcacgggg ccggctcctg ctggtggcca
    23581 ccgagccacg cccgcgcccc cggcgggcga ccgccgggcc ggcgccgtct cgccctccgg
    23641 acgaatttcc ataccgtctg cccaaattga cccctccggt ctactctgga acggtgccgg
    23701 aggacgtggg gggcacgccg ttccctgacg gctgggacgg ccgggagccc gacagcgacc
    23761 ctgaccgcgg agcgtgggac gaagagttcg cctccgtggt cttcgacgag gcgttcgtac
    23821 gggcggccgc ggtgcacgag ccgaccgccg tcgaacgcct cctggccgcc gcccaggcga
    23881 gagccgaggc cgcggagacg gaggcccgcc ggacccaccc cgcaggcgag cggtacgacg
    23941 acggatacgg cggcttcggc cacgcacccg ggctcgacgc cctggacgac gacggcctcg
    24001 acggccccgg tgatcccgcg gggccgtacg gcaggccgct gcgctggcac cgccccgtcg
    24061 cctgggtgct cgccctcgtc atgggcgtcg gcatggtggc gctggccttc gcggcggtct
    24121 accggggcgg gtcctcgggc ggtggcgagc ggaccccgcc gcccgcctcg accagcccgg
    24181 agcagggcgg tgcgacgagc ccctcggtct ccgccggcca ctcccggccg gccgccgtcc
    24241 cggtgatccc gcacagcccc tgacgggcct cactgaccac ccggcggtat ggcacccagg
    24301 tggccgaact tctcgcccgg cagggcgttt accggggctc gcgcagacct accctgaagg
    24361 tatgggaggg cctggagacc cgcctgaggg gacacccgag ggcatcccct caggtggcga
    24421 ggacgagtac cggtccgtcg tcttcgacga gtccttcgtc cgtgctgccc gcctccagga
    24481 gtactccgcc caggagcgca tggccgacca cgcgcccgcc gtgcggcgcc gcccgcccct
    24541 gcgccgggtg cggctgcccc ggcaggccct cgtcctcgtc gtgctgatcg cgatcgcctt
    24601 cggcgccgcc gtcttcatgg gcctgcgccc cccgtaccag acgcccggcg gacaggagcc
    24661 cgccgagccg ctgcgcatga ccgtcgtccc gctcgccccg caggggcggg tgcccggcac
    24721 cgccgagacc gcccacctgt tcgagcgcag ccccgccgcg gaattccgca tgggcgccga
    24781 gggcgtcccg ctgccggccg cgcggcgcac cgcgcacttc tccgacgatc aggtgctcag
    24841 cgccctgacc accgccaagg actacatcgt gcgctccggg ctcgaccccg aggtgctcgg
    24901 cggcggcccg gtccgctccg tgcgggtcct ggtcgacccc gagcagctcg gccagttcga
    24961 cgcgagcttc aagaggcccg ccgccgacgg ccggcacgcg cccaccggat ggctggtgcg
    25021 gttcgacccc tcccgcgtcg agctcgccga ccccgggatc cggacgaatg gcacgctgcg
    25081 ggtggccgag gccgactccg ccaccctgga ggtcaccgcc gaccacacct tcgtctacgc
    25141 gctgcggccc gccggacagg accgggccga ggcgtccctg ttcaccgtcc gccgcgagct
    25201 gcacttccgc ttcgaccggg acgacctgcg tctccaccag gcccagctcg tcctgtccac
    25261 cctccaggcc gggccgctgt cctgcgccga ggactccgcg aaccatctgc gcccgctgct
    25321 cgcgggccag accgccaagg acggcccccc ggccggcacc gacccgtacg tcacgggccg
    25381 ggccacggcc ctgtgcggaa cgctggcggc cggcgcccag ccgaaggtgt gacgcgcggg
    25441 ggcgccgcgg cgggccgtgc cgcgcccacc gcggtcagcc cccgtctcgc cgcggtcagt
    25501 cctcctcgcg cggcggccgg ccgcccggag tcccgccacc gcccggggtc tcgccaccac
    25561 ccggggtccc gccaccgccc ggtgcctccg gacccgcggc gtcccccggt ccgcccgggg
    25621 acttcggcgg gcgcggctgg gagcccgtga agccgccgaa gccgcgccgc atccgctcac
    25681 cgaggtcacc ggcgccgccg gcgaggtcgt tcaccagctt catcagcggg tccttggagg
    25741 tgcgcacctg cgtggcgtag ctggacgccg actcccggaa ggagtcccgg accgaggtgt
    25801 ccccgtcctc gccgcgccgc gggtagtggc cgtccatcag ccgctggtag tcgcgggagg
    25861 cggcccactt cttcagctcg gcggcccgca cggtggtgaa cgggtgcgag cgcggcagca
    25921 cgttgaggat cttcaggacg gagtcgcgca gatcgccgcc ggcctcgtac tcgtcggcct
    25981 gctccaggaa ggcgtcgacg ttcatctcgt gcaggtggtt gccgcccgcg atcttcatca
    26041 ggccgcgcat ggacgcctgg aggtcctggc cggccaggag acccgcgcgg tcggcggaca
    26101 gctccgactt gcggaaccac tcccgcagcg cggtcacgac ggccatgatc gccacgttgc
    26161 ccagcgggat ccaggcgacc cggaccgcga ggctggtgag gaagagcagg acggtccggt
    26221 acacggcgtg gccggacagc gcgtgtccga cctcgtggcc cacgaccgcg cgcatctcct
    26281 cctcgtcgag cagctccacc agcccggtgg tgacgacgat gatcggctcg tccaggccga
    26341 tgcacatcgc gttcggggtc gggtcctggt tgacgtacat cggcgggacc ttctccaggt
    26401 ccaggatgta gcaggcgtcc cgcagcatgt cgttcaggtg ggagaactgc cggtccgaga
    26461 cccgtacgga gtcggacagg aacagcagcc gcaggctccg ctccggcagc aggccgctga
    26521 gcgccttgaa ggccgtgtcg aaaccgctca gcttgcgcag cgccaccagg gcactgcggt
    26581 cggccgggtg ctcgtacgca cgcgaggaga tctccgggaa gcgcctgcgc tgccggcccg
    26641 gcaccttctc cggcccgctg tgctggtggc cgtcggacat gtcttccccc atgcgtgtgt
    26701 gtggggtcct ttacggaccc ttgtgcggcc ctttgtaccc ccgagacaag gcccagccta
    26761 ggcggagata ccgtggacgg gcagtacagc gaaggagacc gcgtcatgga gcacaccccc
    26821 cgcaccgcct ggctcgccga ggccgcgcgc acggccgccg agccgcaggg aacgggaaac
    26881 ctgctccgga tcatcctgat cgtgatggtg gtgggctgtg tgctgaccgc gtggttcctg
    26941 ctgcggggct acaagcgcaa ggacgactga ggcggccgga aggttccccg gcccccgggg
    27001 cggccgggaa ggggcgcggg cgtggccgga gcggacggac gtccccaacg gcggagtcgg
    27061 cgtgatcgcc cgcacggctc ccgcatacga tgagccgacg tctttatccc gcccacacct
    27121 gataggtcct gccgaagatg agcttccaca gcaccgctgc ccagctggtc accctcgccg
    27181 ccgagggcca ggagcacggc ggcaaccacg agagcctcaa cccctacctc accggtggcg
    27241 gcgccttcgt catcctgatg ctgctgctgt ggatcaccac gcgtttcaac cgcgaccgct
    27301 aggggcgtcc cccggggcgg ccctggacca ccccgcgccc ggcccctgga cgccggggag
    27361 cccgggggag gcaggagccc tcggaccggg ccggtagggt ctgcacgcat gggagagcag
    27421 gacatgccta ccggtccggc gcacgacacg gtgagcggcg cacaggagag cccggcgccc
    27481 ggccgcgccg ccggccccgg caacggcccg tggcgcacgg gcaagcgccg cctcggcgtc
    27541 atgggcggca ctttcgaccc gatccaccac gggcacctgg tggcggccag cgaggtcgcc
    27601 gcgcagttcc acctcgacga ggtggtgttc gtccccaccg gccagccgtg gcagaagagc
    27661 caccgcaagg tctccgccgc cgaggaccgc tatctgatga cggtcatcgc gaccgccgag
    27721 aacccgcagt tctcggtgag ccgcatcgac atcgaccgcg gcggccccac ctacaccgtg
    27781 gacaccctgc gcgacctgcg cgccctcaac cccgacacgg acctgttctt catcaccggc
    27841 gccgacgcgc tggcgcagat cctgacctgg cgcgacagcg aggagctgtt ctccctcgcg
    27901 cacttcatcg gcgtcacccg ccccggccac cacctgaccg acgccgggct ccccgagggc
    27961 ggcgtctccc tcgtcgaggt ccccgccctc gccatctcct ccacggactg ccgtgcgaga
    28021 gtcgccaagg gggaccccgt ctggtatctg gtgcccgacg gagtcgtgcg ctacatcgac
    28081 aagcgccagc tgtaccgcgg cgactgagcc gagaggggca ccggtgaacg accgatacga
    28141 cgcggggtac aggaccgacg ggcccgcccc gtacgagctc gtcggctacg acgagtacgg
    28201 ccagcccgtg taccgccagg ccccggtgcg gcaggacacg caccagcagc cgtacgaccc
    28261 gtacgacccc tacaccgcct acgggcagca ggggcagcag gggcagcaga gccacgccta
    28321 cgacccctac gccccggacg ggccgcagac cgccccggcg tacggcaccc cggccgccgg
    28381 cgccgcccag gacccgggac cgcagccccc cgtctccccg tacggcacct cctacgaccc
    28441 gtacgaccct tatgccgccg ccgcccacca gggcgccggg agcgaccggg cgtacgaccc
    28501 ctacgggcag cccgcggccg ggggcgcgca ggcgcgcgtc accgagcaga ccgcctccat
    28561 cccgcagcag gccggcccgc ccgacgagcc ggcgcccgcc gccgggagcg aaggggagta
    28621 ccgcaccgag cagttcgcct tcgtcgagga gccggacggc gactccgagg acgtcatcga
    28681 ctggctgaag ttcaccgaga accgcaccga gcgccgcgag gaggcccgcc gccgcgcacg
    28741 cgcgcgcctg atcgcgctcg ccgtcgtgct ggcgctggtc gcggtcggcg gcgtgggctg
    28801 gctctggtac gccgggaagc tgcccgggct gtcgtcctcg gacaccggga ccggcaccac
    28861 ggcgacgggc gcccagaagc gcgacgtgat cgtcgtccac ctgcacgaca ccaagcaggg
    28921 cggcaccacc acggcgctgc tcgtcgacaa cgccaccgcc gggcagggca ccaccgtcct
    28981 gctgcccaac tccctcacgc tgaccggtga cgacggcacc accaccacgc tcgcccactc
    29041 cgtcgaggac gccggcgccg acggcaccca ggacgcgctc gactcggtcc tcggcacctc
    29101 catccacggc acctggcggc tggacactcc ctacctgcag aacctcgtcg acctggtcgg
    29161 caacatcgac gtcgacaccg acgccgaggt gcccgacccg gactccggga agaaggaccg
    29221 ggcgccgctg gtccacaagg gcacggacca gaccctcagc gggaagatgg cgg
//
