LOCUS       LN831790               21032 bp    DNA     linear   BCT 17-JUN-2020
DEFINITION  Streptomyces leeuwenhoekii strain C34 (= DSM 42122 = NRRL B-24963)
            genome assembly, chromosome: chromosome.
ACCESSION   LN831790
VERSION     LN831790.1
KEYWORDS    .
SOURCE      Streptomyces leeuwenhoekii
  ORGANISM  Streptomyces leeuwenhoekii
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-02-26 04:50:55
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 5653095
            Orig. end    :: 5674127
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21032
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11032]"
                     /cutoff="20000"
                     /detection_rule="(bt1fas or ft1fas or t2fas or fabH)"
                     /neighbourhood="10000"
                     /product="fatty_acid"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11032
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(bt1fas or ft1fas or t2fas or fabH)"
                     /neighbourhood="10000"
                     /product="fatty_acid"
                     /protocluster_number="1"
     cand_cluster    1..21032
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(bt1fas or ft1fas or t2fas or fabH)"
                     /kind="single"
                     /product="fatty_acid"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21032
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="fatty_acid"
                     /region_number="36"
                     /rules="(bt1fas or ft1fas or t2fas or fabH)"
                     /tool="antismash"
     gene            87..1109
                     /gene="sle_48020"
     CDS             87..1109
                     /NRPS_PKS="Domain: PKS_ER (34-338). E-value: 6e-25. Score:
                     79.8. Matches aSDomain: nrpspksdomains_sle_48020_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VWW1"
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR020843"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="InterPro:IPR041694"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VWW1"
                     /gene="sle_48020"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 150.4; E-value: 1.1e-45)"
                     /gene_kind="biosynthetic-additional"
                     /product="Putative NADP-dependent oxidoreductase yfmJ"
                     /protein_id="CQR64260.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.7e-22, bitscore:
                     77.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADSPALPSVSREWHLLSRPVGWPKPEDFALVEAEMPVPGEGQVL
                     VRNRYLSVDPYMRGRMSAAKSYVAPFELGKVMQGGAVGEVVASNAEGLAVGDHVLHFFG
                     WREYAAVDAKHAVKVDPEAAPLSTYLGVLGMTGLTAYAGLLRTAAFKEGDAVFVSGAAG
                     AVGSQVGQIAKLKGASRVIGSAGSAEKVKLLVEEYGFDAAFNYKDGPVSEQLRAAAPDG
                     IDVYFDNVGGDHLEAAIGSLNQGGRIAVCGMISVYNNTEPAPGPKNLARLIQTRGRIEG
                     FLVGDHYDLQPQFVQEVGPWVRDGRLKYRETVVEGIENNLEAFLGVLRGDNIGKMVVKL
                     "
     aSDomain        189..1100
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sle_48020_PKS_ER.1"
                     /evalue="6.00E-25"
                     /label="sle_48020_PKS_ER.1"
                     /locus_tag="sle_48020"
                     /protein_end="338"
                     /protein_start="34"
                     /score="79.8"
                     /tool="antismash"
                     /translation="EMPVPGEGQVLVRNRYLSVDPYMRGRMSAAKSYVAPFELGKVMQG
                     GAVGEVVASNAEGLAVGDHVLHFFGWREYAAVDAKHAVKVDPEAAPLSTYLGVLGMTGL
                     TAYAGLLRTAAFKEGDAVFVSGAAGAVGSQVGQIAKLKGASRVIGSAGSAEKVKLLVEE
                     YGFDAAFNYKDGPVSEQLRAAAPDGIDVYFDNVGGDHLEAAIGSLNQGGRIAVCGMISV
                     YNNTEPAPGPKNLARLIQTRGRIEGFLVGDHYDLQPQFVQEVGPWVRDGRLKYRETVVE
                     GIENNLEAFLGVLRGDNIGKMVV"
     gene            1224..1643
                     /gene="sle_48030"
     CDS             1224..1643
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W583"
                     /db_xref="InterPro:IPR003718"
                     /db_xref="InterPro:IPR015946"
                     /db_xref="InterPro:IPR019953"
                     /db_xref="InterPro:IPR036102"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W583"
                     /gene="sle_48030"
                     /product="Organic hydroperoxide resistance protein"
                     /protein_id="CQR64261.1"
                     /transl_table=11
                     /translation="MPIQQSDVLYTAVATAENGRDGRVATDDGKLDVVVNPPKEMGGSG
                     AGTNPEQLFAAGYSACFQGALGVVARQEGVDVSGSTVTAKVGIGKNDDGFGIIVEISAN
                     IPGVDAQAAKELVEKAHQVCPYSKATRGNITVTLA"
     gene            complement(1738..2889)
                     /gene="sle_48040"
     CDS             complement(1738..2889)
                     /codon_start=1
                     /db_xref="InterPro:IPR001466"
                     /db_xref="InterPro:IPR012338"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W316"
                     /gene="sle_48040"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053:beta-lactamase (Score: 85.2; E-value: 8.1e-26)"
                     /gene_kind="biosynthetic-additional"
                     /product="Beta-Lactamase"
                     /protein_id="CQR64262.1"
                     /transl_table=11
                     /translation="MTQEIHGTVADGFEAVREEFAAFVAGERPDYEGQLCAYVHGRKVV
                     DLWAGEGADAGSLYGVYSATKGAAHLVVALLVQEGTLELDREVAYYWPQFAAEGKDALT
                     LRELLAHRAGVVGADGGFTLEEVADDRAIAERMAGQRPFWRPGTAFGYHALVIGALTGE
                     VVRRATGRTLQEVYEERVRAPFALEFHLGLPSALDARFRTAQRMAPTPEQRALIDAQPT
                     GPHTLTAIAFNRHAAHPTDLETLPNEPVVRAQGPASVGGVASARGLAGLYAAAISEVDG
                     RAPLLKRDTVAEFGQLHSAGHDLVARAHKAYGLGFQATADSAHPFLGAGTIGHSGAGGC
                     QAFADPRSGLAYGYTRRRCAFPGGAAPENNRLAAAVHRAALAR"
     gene            3008..3817
                     /gene="sle_48050"
     CDS             3008..3817
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W0B6"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W0B6"
                     /gene="sle_48050"
                     /product="Protein CysZ homolog"
                     /protein_id="CQR64263.1"
                     /transl_table=11
                     /translation="MRDLGAGFRYLLEGQRWVARHGKSYGFGLLPGLITLVLYAAALVA
                     LALWGEDAVAWATPFADDWASPWAGLFRGFLTAVLFALAMLLAVLTFTAVTLLIGQPFY
                     ESLSEQVDRDLSPDGTAPESGLPLWRELWISARDSLRIVVRAVVWGVLLFALGFVPVAG
                     QTVVPVIGFFVTGFFLTEELTAVALQRRGVELRDRLALLRSRKTLVWGFGTPLGLAFLV
                     PFVAVFLMPGAVAGATLLARDLRGEQNRDRDDDPAGALGAGGDRARP"
     gene            complement(3962..5218)
                     /gene="sle_48060"
     CDS             complement(3962..5218)
                     /codon_start=1
                     /db_xref="InterPro:IPR016125"
                     /db_xref="InterPro:IPR036440"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VUM5"
                     /gene="sle_48060"
                     /product="Uncharacterized protein PA0049"
                     /protein_id="CQR64264.1"
                     /transl_table=11
                     /translation="MSSPRVRTVVLGLVLAAGLTAPVPASAASPGAAAPSPTVEERRLD
                     RAVPQEILRRSGFGRPAAAFARSLDRARSYAEARRTVLREGSALWRRAVDRAQGRGPAG
                     GDLSRDDDRPLYWARLAMTRQVRTWEPEFGLTGPQRARLLDALERTSRGQADLRHPRGK
                     GVKRVLVTGFDPFTLDRDIRISNPSGAAALALDGTVIETADGPARVETAVFPVRWRDFT
                     DGTVERTLRARLPEADLFATVSQGRVGRFDIERTNGAWRGGFPDNDDVARTEPVPVTDP
                     GAAPQWTTTTLPYREITAADTGRFPVYDNTAVTEIPAGGGEPVVRPDGPTPGSTARAGG
                     GGDYLSNEIAYRATLLRDRLGLRRTLPGGHVHTPVLQFGAGNTTEVTDPEFVRNRLAIV
                     AQVRAIVTVALEAAQRTED"
     gene            complement(5546..6517)
                     /gene="sle_48070"
     CDS             complement(5546..6517)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VWW4"
                     /db_xref="InterPro:IPR008183"
                     /db_xref="InterPro:IPR011013"
                     /db_xref="InterPro:IPR014718"
                     /db_xref="InterPro:IPR015443"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VWW4"
                     /gene="sle_48070"
                     /product="Aldose 1-epimerase"
                     /protein_id="CQR64265.1"
                     /transl_table=11
                     /translation="MNERFGTLPDGTPVHRWTLERAGVRVRVLSYGGIVQSAEVPDRDG
                     RSADVVLGFAELDGYLAHPEPYLGALVGRYANRIAGGRFTLDGRTYPLARNNGPNCLHG
                     GERGFDKRVWDVAPVEHGVRLSRVSPDGEEGFPGRLEVSATYTLDATGALRIAYEAVTD
                     APTVVSLTNHSYFRLDGPGAAGGHQLRLAASRYTPVDADLVPTGALEDVTGTRFDFRRA
                     RPAQAGYDHNFALDKGVTDTPVGVAELYAPASGRVLTVATTEPGLQLYTADHLGEPFAP
                     GAGVALETQRFPDSPNRPEFPSAVLRPGEVFRSTTVYGFGTR"
     gene            complement(6554..7507)
                     /gene="sle_48080"
     CDS             complement(6554..7507)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W589"
                     /db_xref="InterPro:IPR013830"
                     /db_xref="InterPro:IPR038885"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W589"
                     /gene="sle_48080"
                     /product="Lipoprotein"
                     /protein_id="CQR64266.1"
                     /transl_table=11
                     /translation="MEERVRGCPTIRRGRGHGSGKGRVPGGRRRRSRAVLAVLAAAAVL
                     GAAGCDTAGGGSAAPESRRSSPAPVWDPSPGSIAAVGDSITRGFDACSVLSDCPEVSWA
                     TGGSPEVNSLAVRLLGKAKAAERSWNYAVTGARMADLPAQMARAAARKPELVTVMVGAN
                     DACRASVAAMTPVADFRAGFEEAMRTLRKTASKAQVYVASVPDLKRLWSQGRTDPLGKR
                     VWELGICPSMLADADALDAAATERRETVRRRVEDYNAVLREVCAADRLCRGDGGAVHAF
                     RFGPAQLSRWDWFHPSVNGQARLAEIAYRAVTAERP"
     gene            7735..8229
                     /gene="sle_48090"
     CDS             7735..8229
                     /codon_start=1
                     /db_xref="InterPro:IPR021491"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W320"
                     /gene="sle_48090"
                     /product="Conserved Hypothetical Protein"
                     /protein_id="CQR64267.1"
                     /transl_table=11
                     /translation="MTTRGVLYVHSAPRALCPHVEWAVAGVLGTRVSLDWIRQPAAPGT
                     LRSEFSWQGQAGTASKLASALRGWHLLRFEVTAEPSSTAEGERYSCTPDLGIFHAVTGI
                     HGDILIPEDRLRAALVRSQRGESDLEAELAKLLGKPWDDELEPFRYAGEGAPVRWLHQV
                     V"
     gene            complement(8301..9638)
                     /gene="sle_48100"
     CDS             complement(8301..9638)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (87-440). E-value:
                     2.6e-48. Score: 156.8. Matches aSDomain:
                     nrpspksdomains_sle_48100_PKS_KS.1"
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W0B9"
                     /db_xref="InterPro:IPR000794"
                     /db_xref="InterPro:IPR014030"
                     /db_xref="InterPro:IPR014031"
                     /db_xref="InterPro:IPR016039"
                     /db_xref="InterPro:IPR017568"
                     /db_xref="InterPro:IPR020841"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W0B9"
                     /gene="sle_48100"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FabF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 371.7; E-value:
                     8.4e-113)"
                     /gene_kind="biosynthetic-additional"
                     /product="3-oxoacyl-[acyl-carrier-protein] synthase 2"
                     /protein_id="CQR64268.1"
                     /sec_met_domain="FabF (E-value: 8e-200, bitscore: 662.4,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRPRHPAVAPLILVNVGERIPVSPTNRTVVVTGIGATTPLGGDA
                     ASTWEGLVAGRSGVKPLEQEWAAEQAVRIAAPVAVEPTEVIPRPQARRLDRSAQFALVA
                     AKEAWADAGFEAKAGEGADIDPDRLGAVIASGIGGVTTLLDQYDVLKEKGVRRVSPHTV
                     PMLMPNSPSANVGLAVGARAGVHTPVSACASGAEAIGYAIEMIRTGRADVVVAGGTEAA
                     IHPLPIAAFGNMMAMSKNNDDPQGASRPYDLARDGFVLGEGAGVIVLESAEHAAARGAR
                     VYAEAVGQGISADSHDIVQPEPEGRGIAHALHNLLDRTDLDPAEIVHVNAHATSTPAGD
                     IAELKALRKVFGDHADHIAVSATKSMTGHLLGGAGGVESVATVLALYHRVAPPTINVEN
                     IDPEAEANADVVRDKARKLPAEGRIAALNDSFGFGGHNVVLAFRSV"
     aSDomain        complement(8319..9377)
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sle_48100_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.60E-48"
                     /label="sle_48100_PKS_KS.1"
                     /locus_tag="sle_48100"
                     /protein_end="440"
                     /protein_start="87"
                     /score="156.8"
                     /tool="antismash"
                     /translation="RPQARRLDRSAQFALVAAKEAWADAGFEAKAGEGADIDPDRLGAV
                     IASGIGGVTTLLDQYDVLKEKGVRRVSPHTVPMLMPNSPSANVGLAVGARAGVHTPVSA
                     CASGAEAIGYAIEMIRTGRADVVVAGGTEAAIHPLPIAAFGNMMAMSKNNDDPQGASRP
                     YDLARDGFVLGEGAGVIVLESAEHAAARGARVYAEAVGQGISADSHDIVQPEPEGRGIA
                     HALHNLLDRTDLDPAEIVHVNAHATSTPAGDIAELKALRKVFGDHADHIAVSATKSMTG
                     HLLGGAGGVESVATVLALYHRVAPPTINVENIDPEAEANADVVRDKARKLPAEGRIAAL
                     NDSFGFGGHNVVL"
     gene            complement(9653..9901)
                     /gene="sle_48110"
     CDS             complement(9653..9901)
                     /NRPS_PKS="Domain: PP-binding (11-77). E-value: 1.5e-18.
                     Score: 59.0. Matches aSDomain:
                     nrpspksdomains_sle_48110_PP-binding.1"
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VUP0"
                     /db_xref="InterPro:IPR001633"
                     /db_xref="InterPro:IPR003231"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR036736"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VUP0"
                     /gene="sle_48110"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /product="Acyl carrier protein"
                     /protein_id="CQR64269.1"
                     /sec_met_domain="PP-binding (E-value: 1.8e-16, bitscore:
                     59.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAATQEEIVAGLAEIVNEIAGIPVEDVQLDKSFTDDLDVDSLSMV
                     EVVVAAEERFDVKIPDEDVKNLKTVGDATEYILKHQA"
     aSDomain        complement(9671..9868)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sle_48110_PP-binding.1"
                     /evalue="1.50E-18"
                     /label="sle_48110_PP-binding.1"
                     /locus_tag="sle_48110"
                     /protein_end="77"
                     /protein_start="11"
                     /score="59.0"
                     /tool="antismash"
                     /translation="LAEIVNEIAGIPVEDVQLDKSFTDDLDVDSLSMVEVVVAAEERFD
                     VKIPDEDVKNLKTVGDATEYI"
     gene            complement(10001..11032)
                     /gene="sle_48120"
     CDS             complement(10001..11032)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VWW7"
                     /db_xref="InterPro:IPR004655"
                     /db_xref="InterPro:IPR013747"
                     /db_xref="InterPro:IPR013751"
                     /db_xref="InterPro:IPR016039"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VWW7"
                     /gene="sle_48120"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acid: fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084:3-oxoacyl-(acyl carrier protein) synthase III
                     (Score: 326.5; E-value: 2.6e-99)"
                     /gene_kind="biosynthetic"
                     /product="3-oxoacyl-[acyl-carrier-protein] synthase 3
                     protein 1"
                     /protein_id="CQR64270.1"
                     /sec_met_domain="fabH (E-value: 8.7e-108, bitscore: 358.8,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKPSKGAPYARIIGVGGYRPTRVVPNEVILEKIDSSDEWIRS
                     RSGIETRHWASPEETVAAMSIEASGKALADAGIDATQIGAVVVSTVSHFSQTPAIATEI
                     ADKLGTDKAAAFDISAGCAGFGYGLTLAKGMIVEGSAEYVLVIGVERLSDLTDLEDRAT
                     AFLFGDGAGAVVVGPSQEPAIGPTVWGSEGDKAETIKQTVPWDRFRTGDVSELPLDAEG
                     NVKFPAITQEGQAVFRWAVFEMAKVAQQALDAAGITPDDLDVFIPHQANVRIIDSMVKT
                     LKLPEHVTVARDIRTTGNTSAASIPLAMERLLATGEAKSGDTALVIGFGAGLVYAATVV
                     TLP"
     gene            complement(11046..11993)
                     /gene="sle_48130"
     CDS             complement(11046..11993)
                     /NRPS_PKS="Domain: PKS_AT (6-285). E-value: 1e-45. Score:
                     148.2. Matches aSDomain: nrpspksdomains_sle_48130_PKS_AT.1"
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W593"
                     /db_xref="InterPro:IPR001227"
                     /db_xref="InterPro:IPR014043"
                     /db_xref="InterPro:IPR016035"
                     /db_xref="InterPro:IPR016036"
                     /db_xref="InterPro:IPR020801"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W593"
                     /gene="sle_48130"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 208.8; E-value: 2.7e-63)"
                     /gene_kind="biosynthetic-additional"
                     /product="Malonyl CoA-acyl carrier protein transacylase"
                     /protein_id="CQR64271.1"
                     /sec_met_domain="PKS_AT (E-value: 1.2e-43, bitscore: 148.2,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVLVAPGQGAQTPGFLTEWLELPGAADRVAAWSDAIGLDLAHYG
                     TKADADEIRDTAVAQPLLVAAGLLSATALGDITGFAPGAVAGHSVGEITAAAFAGVLDD
                     TTALRLVRTRGLAMAEAAAVIETGMSALLGGDPEVSVAHLEKLGLTPANVNGAGQIVAA
                     GTMEQLAALSEDKPEGVRKVVPLKVAGAFHTHHMAPAVETLSKAAAELTPADPALPYVS
                     NKDGRTVATGAEVLDRLVGQVANPVRWDLCMETFKELGVTALIEVCPGGTLTGLAKRAL
                     PGVKTLALKSPADLDAARELVAAASDPAAAAADA"
     aSDomain        complement(11139..11975)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sle_48130_PKS_AT.1"
                     /evalue="1.00E-45"
                     /label="sle_48130_PKS_AT.1"
                     /locus_tag="sle_48130"
                     /protein_end="285"
                     /protein_start="6"
                     /score="148.2"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="PGQGAQTPGFLTEWLELPGAADRVAAWSDAIGLDLAHYGTKADAD
                     EIRDTAVAQPLLVAAGLLSATALGDITGFAPGAVAGHSVGEITAAAFAGVLDDTTALRL
                     VRTRGLAMAEAAAVIETGMSALLGGDPEVSVAHLEKLGLTPANVNGAGQIVAAGTMEQL
                     AALSEDKPEGVRKVVPLKVAGAFHTHHMAPAVETLSKAAAELTPADPALPYVSNKDGRT
                     VATGAEVLDRLVGQVANPVRWDLCMETFKELGVTALIEVCPGGTLTGLAKRALPGVK"
     CDS_motif       complement(11640..11759)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sle_48130_0001"
                     /evalue="3.10E-14"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="sle_48130"
                     /protein_end="118"
                     /protein_start="78"
                     /score="45.0"
                     /tool="antismash"
                     /translation="GFAPGAVAGHSVGEITAAAFAGVLDDTTALRLVRTRGLAM"
     gene            complement(12083..13288)
                     /gene="sle_48140"
     CDS             complement(12083..13288)
                     /codon_start=1
                     /db_xref="InterPro:IPR025736"
                     /db_xref="InterPro:IPR041522"
                     /db_xref="InterPro:IPR042070"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W323"
                     /gene="sle_48140"
                     /product="Uncharacterized protein Rv2242/MT2302"
                     /protein_id="CQR64272.1"
                     /transl_table=11
                     /translation="MPEPETSRTERAAHPAHPHAATLKRLERSSGSLAAQAIARMDETL
                     PWYRAMPPENRSWIGLVAQAGIAAFTEWFRHPEAPQAISTDVFGTAPRELTRAITLRQT
                     VEMVRTTIEVMESAIDEVAAPGDESVLREALLVYAREIAFATAQVYAQAAEARGAWDAR
                     LESLVVNAVLSGEADEGAVSRAAALGWNSPEHVCVVLGTAPDGDSELTVEAIRRAARHA
                     KLQVLTGVLGDRLVVVAGGSDNPLAVAKSLIGPFAQGPVVAGPVVPDLQAATRSAQAAA
                     AGLKACSAWQDAPRPVLADDLLPERAMAGDPSAREQLVEEIYRPLEEAGAALLETLSVY
                     LEQASSLEGAARMLFVHPNTVRYRLRRVTDVTGWSPSDVRSAFTLRIALILGRLADGDT
                     QT"
     gene            13350..14000
                     /gene="sle_48150"
     CDS             13350..14000
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W0C2"
                     /db_xref="InterPro:IPR003829"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR012093"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="InterPro:IPR041602"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W0C2"
                     /gene="sle_48150"
                     /gene_functions="other (smcogs) SMCOG1208:pirin
                     domain-containing protein (Score: 118; E-value: 7.9e-36)"
                     /gene_kind="other"
                     /product="Putative quercetin 2,3-dioxygenase
                     Rv0181c/MT0190"
                     /protein_id="CQR64273.1"
                     /transl_table=11
                     /translation="MDVRRADERYPGGEREAGIETWHAFSFGPHYDPANVRFGALIACN
                     EEHLAPGAGFDEHPHRHTEIVTWVVEGELTHRDSTGRETAVRPGDVQRLSAAGGVRHVE
                     RNDGAAPLTFVQMWLAPREPDGEPSYEVVRGISDATPYAVPGAGAVLHVRRPAAGERWA
                     VPDGAYVYVHVVRGTVRLDGTELGAGDAARVTDARGVDAVAVTRAELLVWEMS"
     gene            complement(13997..14836)
                     /gene="sle_48160"
     CDS             complement(13997..14836)
                     /codon_start=1
                     /db_xref="InterPro:IPR001466"
                     /db_xref="InterPro:IPR012338"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VUP8"
                     /gene="sle_48160"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053:beta-lactamase (Score: 84.1; E-value: 1.8e-25)"
                     /gene_kind="biosynthetic-additional"
                     /product="Beta-Lactamase"
                     /protein_id="CQR64274.1"
                     /transl_table=11
                     /translation="MSLKSLALIENWPVPAAAAGAVRADGTVLGVHGPAGRRFPLASVT
                     KPLAAYAALVAYEEGAIELDEPAGPPGATVRHLLAHTSGLAFDEHRVTAPPGERRLYSN
                     AGFEQLGEHIAKATEIPFAEYLRQAVLEPLGMTSTTLEGSPAKDGVSTVEDLLRFAAEV
                     QAPRLLDPRTVADAMTVQYPGTKGVLPGYGHQNPNDWGLGFEIRDGKSPHWTGASSSPR
                     AFGHFGQSGTFLWIDPGAGAACVALTDRAFGPWATEAWPAFTDAVLAELRGLPQDIP"
     gene            complement(14856..15326)
                     /gene="sle_48170"
     CDS             complement(14856..15326)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VWX2"
                     /db_xref="InterPro:IPR000182"
                     /db_xref="InterPro:IPR016181"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VWX2"
                     /gene="sle_48170"
                     /product="Acetyltransferase"
                     /protein_id="CQR64275.1"
                     /transl_table=11
                     /translation="MSLVRRAVPGDAGEVLRLRQVMIDSMAAAPGSTEWQAASLPILRE
                     KLADADGDFAAFVVDHPRRPGALAALVAGTLEYRIGRAGNPRGLIGYVFSVATDPGARR
                     RGHARACMAELLEWFRERGAGHVMLTASADAEPLYRSLGFTRDSDPSMRLYL"
     gene            15424..15888
                     /gene="sle_48180"
     CDS             15424..15888
                     /codon_start=1
                     /db_xref="GOA:A0A0F7W597"
                     /db_xref="InterPro:IPR000551"
                     /db_xref="InterPro:IPR009061"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W597"
                     /gene="sle_48180"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1171:transcriptional regulator, MerR family (Score:
                     84.3; E-value: 2.3e-25)"
                     /gene_kind="regulatory"
                     /product="Uncharacterized HTH-type transcriptional
                     regulator HI_0186"
                     /protein_id="CQR64276.1"
                     /transl_table=11
                     /translation="MTVTETTTTRAGGCAGPPQGSRRPDGQDRYTISEVAALTGLTAHT
                     LRWYERIGLMPHIDRSHTGQRRYRNRDLDWLDLVGKLRLTGMPVADMVRYAELVREGDH
                     TYAERFALLKATREDVLARITELQGTLAVLDRKINFYADAGRALASERSR"
     gene            15885..16901
                     /gene="sle_48190"
     CDS             15885..16901
                     /codon_start=1
                     /db_xref="InterPro:IPR023210"
                     /db_xref="InterPro:IPR036812"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W327"
                     /gene="sle_48190"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     307.9; E-value: 1.1e-93)"
                     /gene_kind="biosynthetic-additional"
                     /product="Uncharacterized oxidoreductase YccK"
                     /protein_id="CQR64277.1"
                     /transl_table=11
                     /translation="MTDGTITKVELGTDGPEVGVQGLGCMGMSFAYGPADAGTSRATLE
                     RALELGVTLYDTADAYGAGENERFLAPFFQAHRDEIVIATKFALSIPPDDPTRRIVRND
                     PPYIRQAVEASLERLGVEVIDLYYMHRRDVNVPIEETVGTMAELVREGKVKHLGLSEVT
                     ADELRAAHAVHPIAAVQSEWSLFSRDIEAKVVPAARELGVALVPYSPLGRGFLTGSFVH
                     ADKELTAGDFRRQQPRFTGANAAANAALLEPVRTVAEAHGATLGQIALAWAQQRAAVHG
                     LPVVPIPGTRRPERVAENAAATRIVLTEDQLALLEPIAGQVAGDRYADMAFTSAGRE"
     gene            complement(16950..17849)
                     /gene="sle_48200"
     CDS             complement(16950..17849)
                     /codon_start=1
                     /db_xref="InterPro:IPR018649"
                     /db_xref="InterPro:IPR027860"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7W0C5"
                     /gene="sle_48200"
                     /product="Conserved Hypothetical Protein"
                     /protein_id="CQR64278.1"
                     /transl_table=11
                     /translation="MRGEGTKKLVPHTMSRMGDVLAGFHATWEFESDSVLIRYERGIRT
                     PKLLQVLGERRIPLRALADVTLTPGRRGTVVLRAEPRPGADPLMEAAAGQLKEACDPYR
                     LVLPAERETLAEYYADELRARLTEEGPAERHLVAAPEPPRQFKAYDGKASFDGTSVFFR
                     WFWTGASSAKWKAGDQTFAVTDLIGVEWRSPEVFEGHLRLLRRDGAASSAQADQDPAAV
                     VFGLGYGPVHESLPFAAAVLAAVRERGPVAAVPVAAVSRRDPADIAERIRHLGELHQAG
                     LVTDEEFSAKKAELLAEL"
     gene            complement(17868..19106)
                     /gene="sle_48210"
     CDS             complement(17868..19106)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VUQ3"
                     /db_xref="InterPro:IPR010427"
                     /db_xref="InterPro:IPR029058"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VUQ3"
                     /gene="sle_48210"
                     /product="Secreted Protein"
                     /protein_id="CQR64279.1"
                     /transl_table=11
                     /translation="MTSFDTSPQLFETSPGLNVWRALLALAVVFVMLATTGWTALRTQR
                     AATPLAASVGAWERGRIDGRRLPDARTAPARLARFFASLTEGQRAYLARRYPLAVGNMN
                     GAPVELRYRANRLALGQARRAELERMRDSRLSPAGQREAGRRVHRLESLLTPGRHILAF
                     DPDGSGRVAEVFGDLDRADRVSVVVPGVDTDLLTFQRSARRYAAPAGMAEALYAAERRA
                     SPSTRTAVIAWADYTAPSGLGMDAATAMRADAGAVRLNALVRALPGQAPVSLFCHSYGS
                     VVCGRAARALPARVTDITVAGSPGMRAARASQLRTSARVWAMRDADDWIQDVPYLEVGG
                     LGHGADPVSAAFGARVLSARGAEGHSGYFVPGTESLANFAEIGVGSYRSVACAHESGTC
                     HAGLSAATSAGRA"
     gene            complement(19172..19900)
                     /gene="sle_48220"
     CDS             complement(19172..19900)
                     /codon_start=1
                     /db_xref="GOA:A0A0F7VWX8"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR041347"
                     /db_xref="UniProtKB/TrEMBL:A0A0F7VWX8"
                     /gene="sle_48220"
                     /gene_functions="regulatory (smcogs) SMCOG1215:TetR family
                     transcriptional regulator (Score: 194.5; E-value: 3.5e-59)"
                     /gene_kind="regulatory"
                     /product="HTH-type transcriptional regulator tcmR"
                     /protein_id="CQR64280.1"
                     /transl_table=11
                     /translation="MKAAEAAQPAGAARPAGTAQPAGAAHPAPRPGLRERKKRRTRDAL
                     LRAALELFTARGYERTTVDDIAEAADVSQRTFFRYFASKEEAAFFVSRLAEARFVDAVR
                     ARPAGEPPLEALRQSLAESWASIGEAIEQLVPLELHMRFCQVIETTPALLAAHLRRATE
                     LEEEIARVIAEREGLDVDTDPRPRVVVAVFGAVMRVTERIWSARGEATLGALRDLTAAY
                     LDQVEPALTGNWRRGRPPSA"
     misc_feature    20395..20409
                     /note="TFBS match to ZuR, Zinc-responsive repressor,
                     confidence: weak, score: 16.3"
                     /tool="antismash"
ORIGIN
        1 gggtacccag ttgtttgaca agctgaaatg ttcaggcgca tggttgtttc aggtagtgaa
       61 gtaattcgac gaggaaggtg cgccccatgg ccgactcccc cgctctcccc tccgtcagcc
      121 gcgagtggca tctgctgagc cggccggtcg gctggcccaa gcccgaggac ttcgccctgg
      181 tcgaggcgga gatgccggta ccgggcgagg ggcaggtgct ggtccgcaac cggtatctgt
      241 cggtcgaccc gtacatgcgc ggccgcatga gcgccgccaa gtcctacgtc gcccccttcg
      301 agctgggcaa ggtgatgcag ggcggcgcgg tcggcgaggt cgtcgcctcc aacgccgagg
      361 gcctggccgt cggcgaccac gtcctgcact tcttcggctg gcgcgagtac gcggccgtgg
      421 acgccaagca cgccgtcaag gtggaccccg aggccgcgcc gctgtccacg tacctcggcg
      481 tgctgggcat gaccgggctg accgcctacg cgggcctgct gcgcaccgcc gccttcaagg
      541 agggcgacgc ggtgttcgtg tccggcgccg cgggggccgt gggcagccag gtcgggcaga
      601 tcgccaagct caagggcgcc tcccgggtga tcggctccgc cggttcggcg gagaaggtca
      661 agctcctggt cgaggagtac gggttcgacg ccgcgttcaa ctacaaggac gggccggtga
      721 gcgagcagct ccgggccgcc gccccggacg gcatcgacgt ctacttcgac aacgtgggcg
      781 gtgaccacct ggaggccgcc atcggatcgc tcaaccaggg cggccgcatc gccgtctgcg
      841 ggatgatctc cgtctacaac aacaccgagc ccgccccggg gccgaagaac ctcgcgcggc
      901 tcatccagac ccggggccgg atcgagggct tcctcgtcgg cgaccactac gacctccagc
      961 cgcagttcgt gcaggaggtc ggcccgtggg tccgggacgg gcggctgaag taccgcgaga
     1021 ccgtcgtcga gggcatcgag aacaacctgg aggcgttcct cggcgtcctg cgcggcgaca
     1081 acatcgggaa gatggtcgtc aagctctgac ggccgtccgc tccgaccggc cttcaccctg
     1141 tttccggcat gcggtaactt ctttccataa tcagtcgcga tcgtgggcgc gagtcgcggc
     1201 ggaccgagga ggaagacaac cgcatgccga ttcagcagtc cgacgtcctg tacaccgccg
     1261 tcgccaccgc cgagaacggc cgtgacggcc gggtggccac cgatgacggc aagctcgacg
     1321 tggtcgtgaa cccgcccaag gagatgggcg gcagcggcgc cggcaccaac ccggagcagc
     1381 tcttcgccgc cgggtacagc gcctgcttcc agggcgcgct cggcgtggtc gcccgccagg
     1441 agggcgtcga cgtgtccggc tcgaccgtca ccgcgaaggt cgggatcggc aagaacgacg
     1501 acgggttcgg catcatcgtc gagatctccg cgaacatccc gggcgtggac gcccaggccg
     1561 ccaaggagct cgtcgagaag gcccaccagg tgtgcccgta ctcgaaggcc acccgcggca
     1621 acatcaccgt gacgctcgcc tgaccacggt cgttggccac ggcagaggcc gcacccttgg
     1681 acgtggggtg cggcctccgc tccgttctcg gccgttcccg gtcgttcccg gccgttctca
     1741 gcgggccagc gcggcccggt gcaccgcggc cgcgaggcgg ttgttctccg gggcggcccc
     1801 gcccgggaag gcgcaccggc gccgggtgta gccgtaggcg agtccgctgc gcgggtcggc
     1861 gaacgcctgg cagccgcccg cgccgctgtg cccgatcgtc ccggcgccga ggaacgggtg
     1921 cgcgctgtcg gccgtcgcct ggaaaccgag gccgtacgcc ttgtgggcac gggccaccag
     1981 atcgtggccg gccgagtgga gctgaccgaa ctccgccacc gtgtcccgct tcagcagcgg
     2041 tgccctgccg tccacctcgc tgatggccgc cgcgtacagc ccggccagcc cccgcgccga
     2101 cgccacgccg cccaccgacg ccggtccctg ggcgcgcacc acgggctcgt tggggagggt
     2161 ctccaggtcg gtcgggtggg ccgcgtggcg gttgaaggcg atcgccgtca gggtgtgcgg
     2221 cccggtcggc tgggcgtcga tcagcgcccg ctgctccggg gtgggcgcca tgcgctgcgc
     2281 ggtgcggaag cgggcgtcca gggcggacgg caggcccaga tggaactcca gggcgaacgg
     2341 ggcgcggacg cgctcctcgt agacctcctg gagcgtgcgg ccggtggcgc ggcgcaccac
     2401 ctcgcccgtc agggcgccga tcaccagggc gtggtagccg aaggccgtgc cggggcgcca
     2461 gaaggggcgc tggcctgcca tccgttcggc gatcgcccgg tcgtcggcca cctcctccag
     2521 ggtgaagccg ccgtccgcgc cgaccacccc cgcgcggtgc gccagcagct cgcgcagggt
     2581 cagcgcgtcc ttgccctcgg ccgcgaactg cggccagtag taggcgacct cacggtccag
     2641 ctccagcgtg ccctcctgca ccagcagcgc gaccaccaga tgggcggcgc ccttggtggc
     2701 ggagtacacg ccgtacaggg aaccggcgtc cgcaccctcc ccggcccaca ggtcgacgac
     2761 cttgcggccg tgcacgtagg cgcacaactg gccctcgtaa tcgggccgtt caccggccac
     2821 gaacgcggcg aactcctccc gcaccgcctc gaagccgtcg gcgacggtgc cgtggatctc
     2881 ctgcgtcatc cgcttccctc cccagtctcc ggacttccgc agatcgtacg gcgcaccgac
     2941 acctgttcga ccggtcgtca cgggagccgg aatccgcgag ggccgccgcg gccgatagag
     3001 tgccgccatg cgcgatcttg gggcggggtt ccggtacctc ctggagggcc agcgctgggt
     3061 ggcccggcac ggcaagagct acggcttcgg gctgctcccg ggcctgatca ccctggtgct
     3121 gtacgcggcg gcgctggtgg cgctggcgct gtggggcgag gacgcggtgg cctgggcgac
     3181 ccccttcgcc gacgactggg cgagcccctg ggccgggctg ttccgcggct tcctcaccgc
     3241 cgtgctgttc gcgctcgcga tgctgctggc cgtcctgacc ttcaccgcgg tcaccctgct
     3301 gatcggccag cccttctacg agagcctctc cgagcaggtc gaccgcgacc tctccccgga
     3361 cggcaccgcc cccgagtcgg gcctgccgct ctggcgcgag ctgtggatct ccgcccggga
     3421 cagcctgcgg atcgtggtgc gggccgtggt gtggggcgtg ctgctgttcg ccctcgggtt
     3481 cgtaccggtg gcgggccaga ccgtcgtacc ggtgatcggg ttcttcgtca ccggcttctt
     3541 cctcaccgag gagctcaccg ccgtcgccct ccagcgccgc ggggtcgagc tgcgcgaccg
     3601 gctcgccctg ctccgctccc gcaagacgct ggtctggggc ttcggcacgc ccctcggcct
     3661 ggccttcctc gtcccgttcg tcgcggtgtt cctgatgccg ggcgcggtcg ccggtgcgac
     3721 tctcctcgcc cgtgacctgc gcggcgagca gaaccgcgac cgcgacgacg accccgccgg
     3781 cgcgctcggg gcgggaggcg accgcgcccg gccgtgaccg ggacgctcgc cgaagccgaa
     3841 gccgaagccg aagccggacc cggacccgaa gccggagccg gagccgaagc cggagccgga
     3901 gccgaagccg gagccggacc cgaagcctga cccggtgtca ccgtcccggc ctggcgcggc
     3961 gtcagtcctc cgtccgctgc gccgcctcca gtgccacggt cacgatcgcg cgcacctgcg
     4021 cgacgatggc gagccggttg cgcacgaact ccgggtcggt gacctcggtg gtgttcccgg
     4081 cgccgaactg gagcaccggt gtgtgcacat gcccgcccgg cagcgtccgc cgcagcccca
     4141 gccggtcccg cagcagcgtc gcccggtagg cgatctcgtt ggacaggtag tccccgccgc
     4201 ccccggcccg ggccgtcgat ccgggggtcg gcccgtccgg ccgcaccacg ggctcgccgc
     4261 cccccgccgg gatctcggtg acggccgtgt tgtcgtacac cgggaagcgc ccggtgtccg
     4321 ccgccgtgat ctcccggtac ggcagggtgg tcgtcgtcca ctgcggcgcg gcgccgggat
     4381 cggtgaccgg gaccggctcc gtgcgcgcga cgtcgtcgtt gtccgggaaa ccgccccgcc
     4441 aggccccgtt ggtccgctcg atgtcgaacc gcccgacacg gccctggctc accgtcgcga
     4501 acaggtcggc ctccggcagg cgcgcccgca gcgtccgttc caccgtgccg tccgtgaagt
     4561 cccgccagcg caccgggaac acggccgtct ccacccgcgc ggggccatcc gccgtctcga
     4621 tcaccgtgcc gtccagggcg agcgcggcgg caccggaggg gttggagatg cggatgtccc
     4681 ggtccagggt gaacgggtcg aaaccggtga ccaggacgcg cttgacgccc ttgccgcggg
     4741 gatgacgcag gtcggcctgg ccgcgcgagg tgcgctccag cgcgtccagg agccgggccc
     4801 gctgcggccc ggtgagcccg aactccggct cccaggtgcg cacctgacgg gtcatggcca
     4861 gccgcgccca gtacagcggc cggtcgtcgt cccggctgag gtcgccgccc gccgggcccc
     4921 gcccctgcgc ccggtccacg gcccgccgcc acagcgccga gccctcgcgc agcaccgtcc
     4981 gccgggcctc ggcgtaggac cgcgcccggt ccagcgaccg ggcgaaggcg gccgccggac
     5041 ggccgaatcc ggagcgccgc aggatctcct ggggcacggc ccggtccagc cgccgctcct
     5101 cgacggtggg ggacggggcg gcggccccgg gagaggccgc cgacgccggt accggggccg
     5161 tcagccccgc cgcgaggacg agaccgagga cgactgtgcg gacacgtggg gaggacaagg
     5221 cggtcggggt cctttccgtc gccgtggggt gcagccggac cgcggcagta tcgcgtgacg
     5281 gaagcggcgg gcgccatggt gcgtggccca cgggaccggc ggcgggcgca ggccggccac
     5341 aggggagtac ggggaagggg agaggggacg accggttcgt gggcgtgtgt gaaggcttcg
     5401 tacggactcc gggcgggccg ggcgatccgg ggccgcggac cggccgtggc ggctaacgtc
     5461 tgacccggga cccccctccc cccacgccgg cggccccggc ccgggacctg acggccgggc
     5521 cggggcccac ggtgtcttac gggcgtcagc gggtgccgaa gccgtacacc gtcgtggagc
     5581 ggaacacctc gcccggccgc agcaccgcgc tcgggaactc cggccggttc ggcgagtcgg
     5641 ggaagcgctg cgtctccagc gcgacgccgg cgccgggcgc gaacggctcg cccagatggt
     5701 ccgccgtgta gagctggagc cccggttcgg tggtcgccac ggtcagcacc cgcccggagg
     5761 ccggggcgta cagctcggcc acccccacgg gcgtgtccgt cacccccttg tccagcgcga
     5821 agttgtggtc gtagcctgcc tgggccgggc gcgcccggcg gaagtcgaaa cgggtcccgg
     5881 tgacgtcctc cagcgccccg gtcgggacga ggtccgcgtc gaccggggtg taccgggagg
     5941 ccgccagccg cagttggtgg ccgcccgcgg cgccgggccc gtccagccgg aagtagctgt
     6001 ggttggtcag gctcaccacg gtcggcgcgt cggtgaccgc ctcataggcg atccgcagcg
     6061 cgccggtggc gtcgagcgtg tacgtcgccg acacctccag gcgccccggg aagccctcct
     6121 cgccgtccgg gctgacccgg gacaggcgga cgccgtgctc gaccggagcg acgtcccaca
     6181 cccgcttgtc gaagccgcgt tccccgccgt gcaggcagtt cggcccgttg ttccgcgcga
     6241 gcggatacgt ccgcccgtcc agggtgaacc ggccgcccgc gatccggttg gcgtaccggc
     6301 cgaccagcgc gcccaagtac ggctccgggt gcgccagata gccgtccagc tccgcgaatc
     6361 ccagcaccac gtcggcactc cgcccgtcgc ggtccggcac ctcggccgac tgcacgatcc
     6421 cgccgtacga caggacgcgg acccggacgc ccgcgcgttc cagggtccag cggtggacag
     6481 gggtgccgtc gggaagtgtg ccgaaacgtt cgttcatgcg cggaactcta gtgccggggc
     6541 ggatgggtgc tggtcacggc cgctcggccg tgaccgcccg gtaagcgatc tccgccagcc
     6601 gggcctggcc gttcacgctc ggatggaacc agtcccaccg gctcaactgc gcggggccga
     6661 agcggaacgc gtgcaccgcc ccgccgtcgc cgcggcacaa ccggtccgcg gcacagacct
     6721 cccgcaggac cgcgttgtag tcctccaccc gccgccgcac cgtctcccgg cgttcggtcg
     6781 ccgccgcgtc cagggcgtcc gcgtccgcca gcatcgaggg gcagatcccc agctcccaca
     6841 cccgcttgcc cagcgggtcg gtgcgcccct gcgaccacag ccgcttcaga tcgggaacgc
     6901 tcgccacgta cacctgagcc ttggaagcgg tcttgcgcaa cgtgcgcatc gcctcctcga
     6961 acccggcccg gaagtcggcc accggggtca tcgccgccac cgaggcccgg caggcgtcgt
     7021 tcgcccccac catgaccgtc accagctccg gcttgcgcgc cgccgcccgg gccatctgcg
     7081 cgggcagatc cgccatgcgc gccccggtga ccgcgtagtt ccagctccgc tcggccgcct
     7141 tcgccttccc cagcagccgt acggcgagac tgttcacctc cgggctgccg cccgtcgccc
     7201 aggacacctc cgggcagtcc gacaggaccg agcaggcgtc gaagccgcgg gtgatggagt
     7261 cgcccaccgc tgcgatcgaa ccggggctcg ggtcccagac cggggccggg ctgctccgcc
     7321 gcgactcggg ggcggcggac ccgcccccgg ccgtgtcaca gcccgcggcg cccagcacgg
     7381 ccgccgcggc cagcacggcg agaacggccc gcgaacggcg gcgtcggccg cccggcaccc
     7441 ggcccttccc ggagccgtgc ccccggcccc tgcggatcgt cggacagccc ctgactcgtt
     7501 cctccatgcc cgcacaaccg atgaaagacc gtcagggttc ccggtggcgg ccatgcgacg
     7561 gctcacaccc gcacaagcgt cctaccgggt gaataaccga tgattcccgg caccgggacc
     7621 gacggtacgt cacactcctt gcgtcgccgc acggtagcct cgccctcaac gtgaccctcc
     7681 cggtcacggc cgttccgccc gttccgagat gtcccgctct gcccggaggt tccggtgacg
     7741 acacgtggag ttctgtacgt gcactccgcg ccgcgcgcgc tctgcccgca cgtcgagtgg
     7801 gccgtcgccg gtgtgctcgg cacccgggtc agcctggact ggatccggca gcccgcagcc
     7861 cccggcacct tgcgttcgga gttctcctgg cagggccagg cgggcaccgc ctccaagctg
     7921 gcctccgcgc tgcgcggctg gcacctgctg cgcttcgagg tgaccgccga gcccagctcc
     7981 accgccgagg gcgaacgtta cagctgtaca cccgatctgg ggatcttcca cgccgtcacc
     8041 ggcatccacg gcgacatcct gatcccggag gaccggctgc gcgccgccct ggtccgctcg
     8101 cagcgcggcg agagcgacct ggaggccgag ctggccaagc tgctcggcaa gccgtgggac
     8161 gacgagctgg agccgttccg gtacgcgggc gagggcgcgc cggtgcgctg gctgcaccag
     8221 gtggtgtgat ccggcgcctg gacacacgtg aggggccccc accggcggtg ggggcccctc
     8281 acgtacgcgc ggaggcgtga tcagaccgag cggaaggcca gcaccacgtt gtgcccgccg
     8341 aagccgaacg agtcgttcag cgcggcgata cggccctcgg cgggcagctt gcgcgccttg
     8401 tcgcggacga cgtcggcgtt ggcctcggcc tccgggtcga tgttctcgac gttgatggtc
     8461 ggcggggcca cccggtggta cagggcgagc accgtcgcga cggactccac gccgcccgcg
     8521 ccgccgagca gatgaccggt catcgacttg gtcgcggaga ccgcgatgtg gtcggcgtgg
     8581 tcgccgaaga ccttgcgcag cgccttcagc tcggcgatgt caccggccgg ggtcgaggtg
     8641 gcgtgcgcgt tgacgtgcac gatctcggcc gggtccaggt cggtgcggtc cagcaggttg
     8701 tgcagggcgt gcgcgatgcc gcggccctcc ggctccggct gcacgatgtc gtggctgtcg
     8761 gcggagatgc cctggccgac cgcctccgcg tagacgcggg cgccgcgcgc ggcggcgtgc
     8821 tcggcggact ccaggacgat cacgcccgcg ccctcgccga ggacgaaacc gtcgcgggcg
     8881 aggtcgtagg ggcgcgaggc gccctgcggg tcgtcgttgt tcttggacat cgccatcatg
     8941 ttgccgaacg cggcgatggg cagcgggtgg atcgccgcct ccgtaccacc ggccacgacg
     9001 acgtcggcgc ggccggtgcg gatcatctcg atggcgtagc cgatggcctc ggcacccgac
     9061 gcgcaggcgg agaccggggt gtgcacgccc gcccgggcac ccacggccaa ccccacgttg
     9121 gccgacgggc tgttgggcat cagcatcgga acggtgtgcg gggagacgcg gcggacgccc
     9181 ttctccttca gcacgtcgta ctggtccagc agggtcgtca cgccgccgat gccggaggcg
     9241 atgaccgcgc cgagccggtc ggggtcgatg tcggcaccct cgccggcctt cgcctcgaaa
     9301 ccggcgtcgg cccaggcttc cttggccgcg accagcgcga actgtgccga acggtccaga
     9361 cggcgggcct gcggacgcgg gatgacctcg gtcggctcca cggcgaccgg ggccgcgatg
     9421 cggaccgcct gctcggcggc ccactcctgc tccaggggct tgacaccgga acgaccggcg
     9481 accaggccct cccaggtgga ggctgcgtcg ccacccagcg gtgtggttgc gccgataccg
     9541 gtgacgacca cggtgcgatt ggtcggactc acgggaattc tttctccaac gttgacgagg
     9601 atcagcggcg ccaccgccgg gtggcggggc cggggcaccg gcccaggcag gctcaggcct
     9661 ggtgcttgag gatgtactcg gtcgcgtcgc cgaccgtctt gaggttcttg acgtcctcgt
     9721 ccgggatctt gacgtcgaag cgctcttcgg cggcgacgac gacctcgacc atggacagcg
     9781 agtcgacgtc caggtcgtcg gtgaaggact tgtccagctg gacgtcctca accgggatgc
     9841 cggcgatctc gttcacgatc tccgcgagac cggcgacgat ctcttcctga gtggcggcca
     9901 tggtggcgct ccttcgttgt gttcagaggt tgtggcgccc gccgcgtggg cggcaggggg
     9961 cgcttgcccg taccggacgc tcgatccggt acggaagtgc ctaggggagg gtaacgaccg
    10021 tcgcggcgta gacgagaccc gccccgaagc cgatgacgag cgcggtgtcg ccgctcttcg
    10081 cctcgccggt cgccaggagc cgctccatcg cgagcgggat cgaggcggcc gaggtgttgc
    10141 cggtggtgcg gatgtcacgg gcgaccgtga cgtgctccgg cagcttgagt gtcttcacca
    10201 tcgagtcgat gatccgcaca ttggcctggt gcgggatgaa gacgtccagg tcgtccgggg
    10261 tgattccggc cgcgtccagc gcctgctggg cgaccttcgc catctcgaac acggcccagc
    10321 ggaagaccgc ctggccctcc tgcgtgatcg caggaaactt gacgttgccc tcggcgtcga
    10381 ggggcagttc ggagacgtcg ccggtccgga accggtccca cggcaccgtc tgcttgatcg
    10441 tttcggcttt gtcgccctcc gagccccaga cggtcgggcc gatggccggc tcctgcgagg
    10501 ggccgaccac gaccgcgccg gcgccgtcgc cgaagaggaa ggccgtcgcc cggtcctcca
    10561 ggtcggtgag gtcggagagc cgctccacgc cgatgacgag gacgtactcc gccgagccct
    10621 cgacgatcat gcccttggcc agggtgaggc cgtagccgaa gccggcgcag cccgccgaga
    10681 tgtcgaaggc ggcggccttg tcggtgccga gcttgtcggc gatctccgtg gcgatggccg
    10741 gggtctggct gaagtgcgac acggtggaga cgaccacggc gccgatctgc gtggcgtcga
    10801 tcccggcgtc cgccagggcc ttgcccgatg cctcgatgga catcgccgcg acggtctcct
    10861 ccggcgacgc ccagtggcgc gtctcgatgc cggagcggga gcggatccac tcgtcggagg
    10921 agtcgatctt ctccaggatc acctcgttcg gcaccacccg ggtcgggcgg tagccgccga
    10981 cgccgatgat gcgcgcgtac ggggcgccct tgctgggctt gatcttcgcc aatggaggct
    11041 ccttgtcagg cgtccgccgc ggcagcggca ggatcggacg cggcggcgac gagctcgcgg
    11101 gccgcgtcga ggtcggcggg ggacttcagg gccagcgtct tcacgccggg cagcgcccgc
    11161 ttggccagcc cggtgagcgt gccgccgggg cacacctcga tcagggcggt gacgccgagc
    11221 tccttgaagg tctccatgca caggtcccag cggaccgggt tggcgacctg gccgaccagg
    11281 cggtcgagca cctcggcgcc ggtggcgacg gtccggccgt ccttgttgga gacgtagggg
    11341 agcgccgggt ccgcgggcgt gagctccgcg gcggccttgg agagcgtctc cacggcgggg
    11401 gccatgtggt gcgtgtggaa ggcgccggcg accttcagcg ggacgacctt gcggacgccc
    11461 tcgggcttgt cctcgctcag cgcggcgagc tgctccatcg tgccggccgc gacgatctgg
    11521 ccggcgccgt tgacgttggc cggggtcagg ccgagcttct ccaggtgggc gacgctcacc
    11581 tcggggtcgc cgccgagcag ggccgacatg ccggtctcga tgaccgcggc ggcctcggcc
    11641 atcgccaggc cccgggtgcg caccagacgc agggcggtcg tgtcgtcgag gacgcccgcg
    11701 aaggcggcgg ccgtgatctc gccgacgctg tggcccgcga cggcgcccgg cgcgaacccg
    11761 gtgatgtcac cgagtgccgt ggccgacagg agcccggcgg cgaccagcag cggctgggcg
    11821 acggcggtgt cgcggatctc gtccgcgtcg gccttcgtgc cgtagtgggc gaggtcgagt
    11881 ccgatggcgt ccgaccaggc ggcgacgcgg tcggcggcgc cgggcagttc gagccattca
    11941 gtcaggaagc cgggcgtctg ggcgccctgg ccgggagcga cgagtacgag cactctcaca
    12001 ctctctcttg gggacgggca caaccgcccg tggggacagg gacgaagaac acggaggggt
    12061 tttgtggggc tccgacaaaa gactaggttt gcgtatcccc atcggccagg cgccccagga
    12121 tcagcgcgat ccgcagcgtg aacgccgagc gtacatcgga gggcgaccat ccggtgacgt
    12181 cagtcacacg tcggagccgg tagcgcacgg tgttggggtg aacgaagagc atccgcgcgg
    12241 ccccctccag actgctcgcc tgctccagat agacactgag cgtctccagg agcgcggccc
    12301 cggcctcctc gagcggtctg tagatctcct ccaccagctg ctcgcgcgcc gacgggtctc
    12361 cggccatggc gcgctccggc agcagatcgt ccgcaagcac cgggcgcggc gcgtcctgcc
    12421 aggccgagca cgccttgagc ccggccgcgg cggcctgcgc ggaccgggtc gcggcctgca
    12481 ggtccggcac gacggggccg gcgacgaccg gtccctgcgc gaacggcccg atcagcgact
    12541 tggcgaccgc cagcggattg tcgctgccgc ccgccacgac caccagccgg tccccgagca
    12601 cccccgtcag cacctggagc ttggcgtgcc gggcggcccg ccggatcgcc tccacggtca
    12661 gctccgagtc gccgtcgggt gccgtgccca gcaccacgca cacatgctcc ggggagttcc
    12721 agcccagcgc ggcggcccgg gacaccgcgc cctcgtcggc ctccccgctc agcaccgcgt
    12781 tcaccaccag ggactccagc cgcgcgtccc aggcaccgcg tgcctcggcg gcctgggcgt
    12841 acacctgcgc ggtggcgaag gcgatctcgc gggcgtacac gagcagcgcc tcgcgcagca
    12901 ccgactcgtc ccccggcgcg gccacctcgt cgatcgcgga ttccatgacc tcgatcgtgg
    12961 tccgcaccat ctccacggtc tgccgcagcg tgatggcccg ggtcagctcc cgcggcgcgg
    13021 tcccgaagac gtcggtggag atggcctgcg gggcctcggg gtgccggaac cactcggtga
    13081 aggcggcgat gcccgcctgg gcgaccagcc cgatccagga acggttctcc ggaggcatgg
    13141 cccggtacca gggcagcgtc tcgtccatcc gcgcgatggc ctgcgcggcg agggatccgg
    13201 aggaccgctc cagccgcttc agggtggcgg cgtgcggatg ggcggggtgc gcggcgcgtt
    13261 cggtcctgct ggtttcgggt tcgggcacgg gacaagactg ccttatccgg acggcggggc
    13321 gtgccgccgg gtctacggtg gacgccgtga tggacgtacg ccgcgccgac gagcgctacc
    13381 cgggaggcga gcgggaagcc ggcatcgaga cctggcacgc cttctccttc ggcccccact
    13441 acgaccccgc caacgtgcgc ttcggcgccc tgatcgcctg caacgaggag catctggcgc
    13501 ccggcgccgg cttcgacgag cacccgcacc gccacaccga gatcgtcacc tgggtggtcg
    13561 agggggagct gacccaccgg gacagcaccg ggcgcgagac ggccgtgcgc cccggggacg
    13621 tgcagcggct cagcgcggcg ggcggtgtgc ggcacgtcga acgcaacgac ggggccgcgc
    13681 ccctgacgtt cgtgcagatg tggctggccc cccgggagcc ggacggcgag ccgtcctacg
    13741 aggtcgtccg cggcatctcc gacgccaccc cgtacgccgt ccccggagcc ggggcggtcc
    13801 tgcacgtgcg ccggccggcc gcgggggagc ggtgggcggt gccggacggg gcgtacgtgt
    13861 acgtgcacgt ggtgcgcggc acggtccggc tggacggcac ggagctgggc gcgggcgacg
    13921 cggcccgcgt cacggacgcc cggggcgtgg acgcggtcgc ggtgacgcgg gccgaactgc
    13981 tggtgtggga gatgtcttag gggatgtcct ggggcaggcc ccggagttcg gcgaggaccg
    14041 cgtcggtgaa cgccggccac gcctcggtcg cccaggggcc gaacgcacgg tcggtgaggg
    14101 ccacgcaggc cgccccggcg ccggggtcga tccacaggaa cgtacccgac tgcccgaaat
    14161 gcccgaacgc gcggggcgag gacgacgcac ccgtccagtg cggggacttg ccgtcgcgga
    14221 tctcgaagcc gaggccccag tcgttggggt tctggtggcc gtagccgggc agcacgccct
    14281 tggtgcccgg gtactgcacc gtcatcgcgt cggcgaccgt gcgcgggtcg agcaggcgcg
    14341 gcgcctgcac ctcggccgcg aaccgcagca ggtcctccac cgtggagacc ccgtccttgg
    14401 cgggggagcc ctccagtgtg gtggaggtca tacccagcgg ctccagcacc gcctgccgca
    14461 ggtactcggc gaacgggatc tccgtcgcct tcgcgatgtg ttcgccgagc tgctcgaaac
    14521 cggcgttgga gtacagccgc cgctccccgg gcggggcggt gaccctgtgc tcgtcgaagg
    14581 cgagaccgga ggtgtgggcg agcaggtgcc ggaccgtcgc gccgggcggc ccggcgggct
    14641 cgtccagctc gatcgcgccc tcctcgtagg cgaccagggc cgcgtacgcg gcgagcggct
    14701 tggtgaccga ggccagcggg aaccgccgtc cggccgggcc gtgcaccccc aggaccgtgc
    14761 cgtccgcccg tacggcaccc gccgcggcgg cgggaaccgg ccagttctcg atcaacgcga
    14821 ggctcttcaa ggacatgcct gtgagcctaa gcggctcaca ggtacagccg catcgagggg
    14881 tcggagtccc gggtgaaacc cagcgaccgg tacagcggct cggcgtcggc ggaggcggtc
    14941 agcatcacgt gcccggcgcc ccgctcgcgg aaccactcca ggagctccgc catgcaggcc
    15001 cgggcgtggc cgcgccgccg cgccccgggg tcggtcgcga cgctgaagac gtacccgatc
    15061 agcccgcgcg ggttgcccgc ccggccgatc cggtactcca gcgtcccggc cacgagtgcc
    15121 gccagcgccc cgggccgccg cggatggtcc acgacgaacg cggcgaagtc cccgtccgcg
    15181 tcggccagtt tctcccgcag gattggcagg gaggcagcct gccactcggt ggacccgggc
    15241 gcggccgcca tggagtcgat catcacctgg cgcagacgca ggacttcccc ggcgtccccg
    15301 ggcacggcac ggcgtacgag actcatggcc ccgcacgcta gccagtgccg gcatcgctcg
    15361 tccgcccatt ttccgccgcc cgtccttgct tggagcgcac tccagggttc tagcgtggtg
    15421 gccatgacgg tgacggagac cacgaccacc cgggccggcg gctgcgccgg gccgccccag
    15481 gggagccggc gtccggacgg gcaggacagg tacacgatca gtgaggtcgc cgccctcacc
    15541 ggcctgacgg cgcacaccct gcgctggtac gagcggatcg gcctgatgcc gcacatcgac
    15601 cggtcgcaca ccggtcagcg ccgctaccgc aaccgcgacc tcgactggct cgacctcgtc
    15661 ggcaagctgc ggctgaccgg gatgccggtc gcggacatgg tgcggtacgc ggaactggtg
    15721 cgcgagggcg accacaccta cgccgagcgc ttcgcgctgc tgaaggcgac cagggaggac
    15781 gtcctggcca ggatcaccga actccagggc acgctcgccg tgctcgaccg gaagatcaat
    15841 ttctacgcgg acgccgggcg ggccctggcg tcggagaggt cccgatgacg gacggcacga
    15901 tcacgaaggt ggagctgggc acggacggtc ccgaggtggg cgtccagggc ctgggctgca
    15961 tgggcatgag cttcgcctac ggaccggcgg acgccggcac atcccgggcg accctggagc
    16021 gggcgctcga actcggtgtc accctgtacg acacggcgga cgcctacggg gcgggggaga
    16081 acgagcggtt cctcgccccg ttcttccagg cgcaccgcga cgagatcgtc atcgccacca
    16141 agttcgccct gtcgatcccg ccggacgacc cgacccggcg catcgtccgc aacgacccgc
    16201 cgtacatccg ccaggccgtc gaggccagcc tcgagcgcct cggcgtcgag gtgatcgacc
    16261 tctactacat gcaccggcgg gacgtgaacg tcccgatcga ggagaccgtc ggcaccatgg
    16321 cggagctggt gcgcgagggc aaggtcaagc acctggggct cagcgaggtc accgccgacg
    16381 agctgcgggc cgcgcacgcc gtgcacccga tcgccgccgt gcagtcggag tggtcgctgt
    16441 tcagccggga catcgaggcg aaggtggtgc cggccgcccg cgagctgggc gtggccctcg
    16501 tgccgtactc gcccctcggc cggggctttc tgaccgggtc cttcgtccac gccgacaagg
    16561 agctgacggc cggtgacttc cgccgccagc agccccgctt caccggtgcc aacgccgccg
    16621 ccaacgcggc gctgctggag ccggtgcgca ccgtggccga ggcccacggc gccaccctcg
    16681 ggcagatagc gctggcctgg gcgcagcagc gggcggcggt gcacggcctg ccggtggtgc
    16741 cgatcccggg cacccgcagg ccggagcggg tggcggagaa cgcggcggcc acccgcatcg
    16801 tcctgacgga ggatcagctc gcgctgctgg agccgatcgc cggccaggtg gccggggacc
    16861 ggtacgcgga catggccttc acctcggcgg ggcgggagtg agctgacccc tccggcgcgc
    16921 cgggcgggcg cgcggccggg gccgggcggt cacagctcgg ccagcagctc ggccttcttg
    16981 gcggagaact cctcgtccgt caccagcccc gcctggtgca gctcaccgag gtgacggatg
    17041 cgctcggcga tgtcggcggg gtcacggcgg gagaccgccg ccaccgggac cgcggccacc
    17101 gggccgcgct cccggaccgc cgccagcacg gcggcggcga acggcagcga ctcgtgcacc
    17161 ggcccgtagc cgagcccgaa caccacggcc gccggatcct ggtcggcctg cgcggacgag
    17221 gcggccccgt cacgccgcag cagccgcaga tgcccctcga acacctccgg ggaccgccac
    17281 tccaccccga tcaggtcggt gaccgcgaac gtctggtcac cggccttcca cttcgccgac
    17341 gaggcgcccg tccagaacca gcggaagaac accgacgtac cgtcgaagga cgccttcccg
    17401 tcgtacgcct tgaactgccg cggcggctcc ggggcggcca ccaggtgacg ctcggccggg
    17461 ccctcctcgg tgagccgcgc ccgcagctcg tcggcgtagt actcggcgag cgtctcccgc
    17521 tcggccggca gcaccagccg gtaggggtcg cacgcctcct tcagctgtcc cgccgccgcc
    17581 tccatcagtg ggtcggcgcc gggtcgcggc tcggcgcgca gcaccacggt gccgcgcctg
    17641 ccgggcgtca gcgtgacgtc cgcgagcgcc cgcaggggga ttcggcgttc ccccagcacc
    17701 tgcagcagct tcggtgtccg tatcccccgt tcgtaacgga tgagcacgga gtcggactcg
    17761 aactcccagg tggcatgaaa tccggccagt acgtcaccca tgcggctcat cgtatgcggc
    17821 acgagcttct tcgtcccctc cccgcgcaca ccgcagtttc tccgcagcta cgcgcgtccg
    17881 gccgaggtcg cggcggacaa accggcatgg catgtgccgg attcatgggc gcaggccacc
    17941 gaacggtatg agccgacgcc gatctcggcg aagttggcca ggctctccgt ccccgggacg
    18001 aagtagccgc tgtgcccctc ggcgccgcgc gccgacagca cccgcgcccc gaaggccgcc
    18061 gacaccgggt cggcgccgtg gcccagcccg ccgacttcca gatacggcac gtcctggatc
    18121 cagtcgtcgg cgtcccgcat cgcccacacc cgggccgagg tgcgcaactg ggacgcccgc
    18181 gcggcgcgca tgccggggct gccggccacc gtgatgtcgg tgacccgggc gggcagcgcc
    18241 cgggcggccc ggccgcacac caccgagccg tagctgtggc agaacagcga gacgggcgcc
    18301 tgccccggca gggcgcgcac cagcgcgttc agccggacgg ccccggcgtc ggcgcgcatc
    18361 gcggtggccg cgtccatgcc cagcccgctg ggcgcggtgt agtcggccca ggcgatcacg
    18421 gccgtacggg tcgaggggct cgcccggcgc tcggccgcgt acagcgcctc ggccatgccg
    18481 gcgggcgccg cgtaccggcg cgcggagcgc tggaaggtga gcaggtcggt gtcgacaccg
    18541 gggacgacca cggacacgcg gtcggcgcgg tcgaggtcgc cgaagacctc cgcgacgcgg
    18601 ccggagccat cggggtcgaa ggcgaggatg tgccggcccg gcgtcagcag cgactccagg
    18661 cggtgcacgc ggcggcccgc ctcccgctgc ccggccgggc tgagccggct gtcacgcatc
    18721 cgctccagct cggcccggcg ggcctggccg agcgcgaggc ggttggcgcg gtagcgcagc
    18781 tcgacggggg cgccgttcat gttgccgacc gcgagcggat agcggcgggc gaggtaggcc
    18841 cgctgcccct cggtgagcga ggcgaagaac cgcgccagcc gggccggggc cgtccgcgcg
    18901 tccggcagcc ggcggccgtc gatccggccg cgctcccagg cgccgaccga ggcggccagc
    18961 ggcgtggccg cccgctgggt gcgcagggcg gtccagccgg tggtcgccag catcacgaac
    19021 acgaccgcca gggcgagcag cgcacgccac acgttcagcc cgggggaggt ctcgaacagt
    19081 tgcggggagg tgtcgaagga agtcactggg aggacacact aggagaacga gacggtctcg
    19141 cgtgagccaa gtgactggtc tcacgtttgg gtcacgccga agggggtcgg cccctccgcc
    19201 agttcccggt cagcgcgggt tccacctggt cgagataggc cgccgtcaga tcgcgcaggg
    19261 ccccgagggt ggcctcgccc ctcgcggacc agatccgttc ggtgacccgc atcaccgcgc
    19321 cgaagacggc caccaccacg cgcggacgcg ggtcggtgtc cacgtccagg ccctcccgtt
    19381 cggcgatcac ccgcgcgatc tcctcctcca gctccgtcgc gcgccgcaga tgggcggcga
    19441 gcagggcggg cgtcgtctcg atcacctgac agaagcgcat gtgcagctcc agcggcacga
    19501 gctgctcgat ggcctctccg atcgaggccc agctctcggc cagggactgc cgcagcgcct
    19561 ccaggggcgg ttcgcccgcg gggcgggcgc gcaccgcgtc gacgaagcgc gcctccgcga
    19621 gccgcgacac gaagaacgcg gcctcctcct tgctggcgaa atagcggaag aaggtgcgct
    19681 gcgagacgtc ggcggcctcg gcgatgtcgt cgacggtcgt ccgctcgtac ccccgcgcgg
    19741 tgaacagctc cagagcggcc cgcagcagcg cgtcccgggt gcgccgcttc ttgcgttcgc
    19801 gcaggccggg ccggggcgcc gggtgtgcgg cgcccgcggg ctgcgcggtg cctgcgggcc
    19861 gcgcggcgcc tgccggctgt gccgcttctg ctgccttcaa cggacctcgg gcctctcgga
    19921 cgaactgttc tcccagttca ggctataggg gagtgtcctg tcagttaccg acttgtgaat
    19981 tggtttgtca attgtcagtg gctgtcacta gcctcgaatg tatgactagt cagaccacca
    20041 ttgacacgac ggggccgggg gaccaggcac caactgcccc gtcgggcaag acgccggcca
    20101 aggggctgcg cggccatccg tggttcaccc tcatcaccgt cgcggtcggg gtgatgatgg
    20161 tggccctcga cggcaccatc gtcgccatcg ccaacccggc catcgccagc gacctcggcg
    20221 ccaccttcgc cgaggtgcag tggatcacca acgcctactt cctcgccctc gcggtctccc
    20281 tgatcaccgc gggcaagctc ggtgaccgct tcggccaccg gcagaccttc ctcataggcg
    20341 tcgtcggctt cgccgccgcc tccggggcca tcgggatgtc cgacagcatc gcgctggtca
    20401 tcgtcttccg tgtcctccag ggcctgttcg gcgcgctgct gatgccggcc gcgctcggcc
    20461 tgctgcgggc caccttctcc gccgacaagc tgaacatggc catcggcatc tggggcatgg
    20521 tcatcggggc ctccaccgcg ggcggcccca tcctcggcgg cgtgctggtc gagcacgtca
    20581 actggcagtc ggtgttcttc atcaacgtgc cggtcggtgt cctcgccgtc gtcctcggtg
    20641 tcatgatcct gctcgaccac cgggccgaga acgctccgcg ctccttcgac atcctcggca
    20701 tcgcgctgct gtcggccgcg atgttctgcc tggtctgggc cctgatcaag gccccggagt
    20761 ggggctgggg caacggcacg acgtggacct tcgtcctcgc ctccgtggtg ggcttcgcgc
    20821 tcttcgccct ctgggagacg aaggtgaagg agccgctgat cccgctcgcg ctgttccgct
    20881 ccgtgccgct gtcggcgggt gtggtgctga tggtcctgat ggccatcgcc ttcctgggcg
    20941 gtctgttctt cgtcaccttc tatctgcaga acgtgcacgg catgagcccg gtcgacgccg
    21001 gtctccatct gctgccgctc accggcatga tg
//
