LOCUS       k141_1093               2201 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  k141_1093 flag=1 multi=118.0000 len=2201.
ACCESSION   k141_1093
VERSION     k141_1093
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2022-10-05 22:35:42
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2201
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     PFAM_domain     1..99
                     /aSDomain="ACP_syn_III"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08545.12"
                     /db_xref="GO:0004315"
                     /db_xref="GO:0006633"
                     /description="3-Oxoacyl-[acyl-carrier-protein (ACP)]
                     synthase III"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1079_1_0001"
                     /evalue="4.80E-09"
                     /gene_ontologies="GO:0004315:
                     3-oxoacyl-[acyl-carrier-protein] synthase activity"
                     /gene_ontologies="GO:0006633: fatty acid biosynthetic
                     process"
                     /label="ctg1079_1"
                     /locus_tag="ctg1079_1"
                     /protein_end="33"
                     /protein_start="0"
                     /score="36.0"
                     /tool="antismash"
                     /translation="RTTCVLFGDGAGAAVLKADSETGILSTHLHADG"
     CDS             1..519
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acid: fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084:3-oxoacyl-(acyl carrier protein) synthase III
                     (Score: 165.8; E-value: 2.1e-50)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1079_1"
                     /sec_met_domain="fabH (E-value: 8.7e-69, bitscore: 219.7,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="RTTCVLFGDGAGAAVLKADSETGILSTHLHADGSKKELLWNPVGV
                     SKGFNPDEPNNGIRIHMKGNDVFKYAVKALDSVVDETLDANGLDKHDLDWLIPHQANLR
                     IIEATAKRLDMSMDQVIVTVDKHGNTSSGSVPLALDTAVRSGRVERGQLLLLEAFGGGF
                     TWGSVLLRY"
     protocluster    1..2201
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[0:519](+)"
                     /cutoff="20000"
                     /detection_rule="(bt1fas or ft1fas or t2fas or fabH)"
                     /neighbourhood="10000"
                     /product="fatty_acid"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..519
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(bt1fas or ft1fas or t2fas or fabH)"
                     /neighbourhood="10000"
                     /product="fatty_acid"
                     /protocluster_number="1"
     cand_cluster    1..2201
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(bt1fas or ft1fas or t2fas or fabH)"
                     /kind="single"
                     /product="fatty_acid"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..2201
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="fatty_acid"
                     /region_number="1"
                     /rules="(bt1fas or ft1fas or t2fas or fabH)"
                     /tool="antismash"
     PFAM_domain     247..516
                     /aSDomain="ACP_syn_III_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08541.12"
                     /description="3-Oxoacyl-[acyl-carrier-protein (ACP)]
                     synthase III C terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1079_1_0002"
                     /evalue="3.00E-36"
                     /label="ctg1079_1"
                     /locus_tag="ctg1079_1"
                     /protein_end="172"
                     /protein_start="82"
                     /score="123.5"
                     /tool="antismash"
                     /translation="LDANGLDKHDLDWLIPHQANLRIIEATAKRLDMSMDQVIVTVDKH
                     GNTSSGSVPLALDTAVRSGRVERGQLLLLEAFGGGFTWGSVLLRY"
     CDS             699..1658
                     /NRPS_PKS="Domain: PKS_AT (13-297). E-value: 8.8e-64.
                     Score: 207.5. Matches aSDomain:
                     nrpspksdomains_ctg1079_2_PKS_AT.1"
                     /NRPS_PKS="type: PKS/NRPS-like protein"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 301.8; E-value: 1.9e-91)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1079_2"
                     /sec_met_domain="PKS_AT (E-value: 4.8e-65, bitscore: 207.5,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQGVRVTSTQLAFVFPGQGSQSVGMLAELSELHPLVRETFAEASE
                     GAGVDLWALSQGGPEEMLNRTEYTQPALLAAGIAVWRAWQQQGGAQPSQLAGHSLGEYT
                     ALVAAGALSLKDGAHLVRLRGQLMQDAAPAGVGAMAAVLGAEDAMVAEVCAQASDSKVV
                     VPANYNSPGQIVIGGDADAVDRAVAMLTERGIRKVVKLAVSVPSHTPLMREAANRLAEV
                     MAGLSWHAPSLPVVQNVDAKVHDGVDAIRDALVRQLYLPVRWTDCVQVLASNGATRIAE
                     CGPGKVLAGLAKRIDKGLDARAIGGVGDFQGALADWQA"
     aSDomain        726..1589
                     /aSDomain="TIGR00128"
                     /aSTool="tigrfam"
                     /description="fabD: malonyl CoA-acyl carrier protein
                     transacylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1079_2_0001"
                     /evalue="5.60E-103"
                     /identifier="TIGR00128"
                     /label="ctg1079_2"
                     /locus_tag="ctg1079_2"
                     /protein_end="297"
                     /protein_start="9"
                     /score="342.3"
                     /tool="antismash"
                     /translation="QLAFVFPGQGSQSVGMLAELSELHPLVRETFAEASEGAGVDLWAL
                     SQGGPEEMLNRTEYTQPALLAAGIAVWRAWQQQGGAQPSQLAGHSLGEYTALVAAGALS
                     LKDGAHLVRLRGQLMQDAAPAGVGAMAAVLGAEDAMVAEVCAQASDSKVVVPANYNSPG
                     QIVIGGDADAVDRAVAMLTERGIRKVVKLAVSVPSHTPLMREAANRLAEVMAGLSWHAP
                     SLPVVQNVDAKVHDGVDAIRDALVRQLYLPVRWTDCVQVLASNGATRIAECGPGKVLAG
                     LAKRIDK"
     CDS_motif       735..785
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1079_2_0001"
                     /evalue="1.10E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ctg1079_2"
                     /protein_end="29"
                     /protein_start="12"
                     /score="20.8"
                     /tool="antismash"
                     /translation="FVFPGQGSQSVGMLAEL"
     PFAM_domain     735..1508
                     /aSDomain="Acyl_transf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00698.23"
                     /description="Acyl transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1079_2_0003"
                     /evalue="1.70E-38"
                     /label="ctg1079_2"
                     /locus_tag="ctg1079_2"
                     /protein_end="270"
                     /protein_start="12"
                     /score="133.1"
                     /tool="antismash"
                     /translation="FVFPGQGSQSVGMLAELSELHPLVRETFAEASEGAGVDLWALSQG
                     GPEEMLNRTEYTQPALLAAGIAVWRAWQQQGGAQPSQLAGHSLGEYTALVAAGALSLKD
                     GAHLVRLRGQLMQDAAPAGVGAMAAVLGAEDAMVAEVCAQASDSKVVVPANYNSPGQIV
                     IGGDADAVDRAVAMLTERGIRKVVKLAVSVPSHTPLMREAANRLAEVMAGLSWHAPSLP
                     VVQNVDAKVHDGVDAIRDALVRQLYLPVRWTDCVQV"
     aSDomain        738..1589
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1079_2_PKS_AT.1"
                     /evalue="8.80E-64"
                     /label="ctg1079_2_PKS_AT.1"
                     /locus_tag="ctg1079_2"
                     /protein_end="297"
                     /protein_start="13"
                     /score="207.5"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VFPGQGSQSVGMLAELSELHPLVRETFAEASEGAGVDLWALSQGG
                     PEEMLNRTEYTQPALLAAGIAVWRAWQQQGGAQPSQLAGHSLGEYTALVAAGALSLKDG
                     AHLVRLRGQLMQDAAPAGVGAMAAVLGAEDAMVAEVCAQASDSKVVVPANYNSPGQIVI
                     GGDADAVDRAVAMLTERGIRKVVKLAVSVPSHTPLMREAANRLAEVMAGLSWHAPSLPV
                     VQNVDAKVHDGVDAIRDALVRQLYLPVRWTDCVQVLASNGATRIAECGPGKVLAGLAKR
                     IDK"
     CDS_motif       963..1085
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1079_2_0002"
                     /evalue="7.80E-18"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg1079_2"
                     /protein_end="129"
                     /protein_start="88"
                     /score="56.6"
                     /tool="antismash"
                     /translation="GAQPSQLAGHSLGEYTALVAAGALSLKDGAHLVRLRGQLMQ"
     CDS             1723..2199
                     /NRPS_PKS="Domain: PKS_KR (9-159). E-value: 3e-16. Score:
                     51.7. Matches aSDomain: nrpspksdomains_ctg1079_3_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     147.2; E-value: 9.7e-45)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1079_3"
                     /sec_met_domain="adh_short (E-value: 3.7e-37, bitscore:
                     115.7, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKPLQGEIALVTGASRGIGAAIADALAAQGATVIGTATSASGAQ
                     AIGERLAATGGHGRELNVTDSAAVDALIDGIAKEFGAISILVNNAGITRDNLLMRMKDE
                     DWQAILDTNLTSVYRTSKAVMRGMMKARKGRIINIASVIGVTGNAGQANYAAAKA"
     PFAM_domain     1747..2199
                     /aSDomain="adh_short"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00106.27"
                     /db_xref="GO:0055114"
                     /description="short chain dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1079_3_0004"
                     /evalue="1.60E-41"
                     /gene_ontologies="GO:0055114: oxidation-reduction process"
                     /label="ctg1079_3"
                     /locus_tag="ctg1079_3"
                     /protein_end="159"
                     /protein_start="8"
                     /score="142.1"
                     /tool="antismash"
                     /translation="IALVTGASRGIGAAIADALAAQGATVIGTATSASGAQAIGERLAA
                     TGGHGRELNVTDSAAVDALIDGIAKEFGAISILVNNAGITRDNLLMRMKDEDWQAILDT
                     NLTSVYRTSKAVMRGMMKARKGRIINIASVIGVTGNAGQANYAAAKA"
     aSDomain        1750..2199
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1079_3_PKS_KR.1"
                     /evalue="3.00E-16"
                     /label="ctg1079_3_PKS_KR.1"
                     /locus_tag="ctg1079_3"
                     /protein_end="159"
                     /protein_start="9"
                     /score="51.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGASRGIGAAIADALAAQGATVIGTATSASGAQAIGERLAAT
                     GGHGRELNVTDSAAVDALIDGIAKEFGAISILVNNAGITRDNLLMRMKDEDWQAILDTN
                     LTSVYRTSKAVMRGMMKARKGRIINIASVIGVTGNAGQANYAAAKA"
     CDS_motif       1753..1884
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1079_3_0001"
                     /evalue="6.80E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg1079_3"
                     /protein_end="54"
                     /protein_start="10"
                     /score="18.7"
                     /tool="antismash"
                     /translation="LVTGASRGIGAAIADALAAQGATVIGTATSASGAQAIGERLAAT"
ORIGIN
        1 cgcaccacct gcgtgctgtt cggcgacggc gccggtgcgg ccgtgctcaa ggccgacagc
       61 gagaccggca tcctcagcac ccatctgcac gccgacggca gcaagaagga actgctgtgg
      121 aatcccgtcg gcgtgtccaa ggggttcaac ccggacgagc cgaacaacgg catccgcatc
      181 cacatgaaag gcaacgacgt cttcaagtac gccgtgaaag ccctcgacag cgtggtcgac
      241 gagacgctcg acgccaatgg cctggacaag cacgatctgg actggctgat tccgcaccag
      301 gccaaccttc gcatcatcga agccaccgcc aagcgactgg acatgtcgat ggaccaggtc
      361 atcgtgaccg tcgacaagca tggcaacacc tcgtccggct ccgtgccgct ggcgttggat
      421 acggccgtgc gctccggccg cgtggagcgt ggccagttgc tgctgctgga agccttcggt
      481 ggcggattca cgtggggctc ggtgctgctg cgctactgag ttccgcgtgg cggaaccgac
      541 agaaggcgat gctgcgaagc atcgccttct tcgtttcggg cctcgtgctt cgataccgcg
      601 agaatccacg tgcatgtgcc cgcgacatcg cgtcgcaggg catacgcccc ggtacagaca
      661 atccggcggg ttcgcccgta tcatcgccgc ctgatttcat gcagggtgtc cgagtgactt
      721 ccacgcaact cgctttcgtt ttcccgggcc aggggtcgca gtccgtcggt atgctggccg
      781 agctgtccga actgcatccg ctcgtgcgcg agacgttcgc cgaagcctcc gaaggtgctg
      841 gcgtcgacct gtgggcgctg tcgcagggcg ggcccgaaga aatgctcaac cgcaccgaat
      901 acacgcagcc cgcgctgctc gcggccggca tcgccgtgtg gcgcgcatgg caacagcagg
      961 gcggcgcgca gccttcgcag ctggccggcc atagtctggg tgagtacacc gcgctggtcg
     1021 ccgccggtgc gctgtcgctc aaggacggcg cgcatctcgt gcgtctgcgc gggcagctga
     1081 tgcaggacgc tgcgcccgca ggtgtcggtg cgatggcggc cgtgctgggc gccgaggatg
     1141 cgatggtggc ggaggtctgc gcgcaggcat ccgacagcaa ggtcgtcgtg cccgccaact
     1201 acaactcgcc gggccagatc gtgatcggcg gcgacgccga cgcggttgat cgcgcggtcg
     1261 cgatgctgac cgagcgcggc atccgcaagg tggtgaaact ggcggtcagc gtgccgtcgc
     1321 acacgccgct gatgcgcgaa gccgccaatc ggctggcgga ggtcatggcc ggtctgtcgt
     1381 ggcatgcacc gtcgctgccg gtggtgcaga acgtcgacgc caaggtgcac gacggcgtgg
     1441 atgcgatccg cgacgccctg gtgcgccagc tgtacctgcc cgtgcgctgg accgactgcg
     1501 tgcaggtact ggcatcgaac ggcgccacgc gcatcgccga atgcggcccc ggcaaggtgc
     1561 tggccggtct ggcgaagcgc atcgacaagg gcttggatgc acgcgccatc ggtggcgtgg
     1621 gcgatttcca gggcgcactc gcggactggc aggcttgacg cacgctgcgt cccttcgctt
     1681 atcctgatcc gctgcatgcc gaaccgtttc gaggacatca tcatgagcaa gcccctgcag
     1741 ggtgaaatcg cactggtcac cggcgccagc cgcggcattg gcgccgccat cgccgacgca
     1801 ctggccgcgc agggcgcgac ggtgatcggt accgcgacca gcgcttccgg cgcacaggcc
     1861 atcggcgagc ggcttgccgc cacaggcggc cacggtcgcg agctgaatgt cacggattcg
     1921 gccgcggtcg atgcgctgat cgatggcatc gcgaaggagt tcggtgccat ctcgatcctg
     1981 gtcaacaacg ccggcatcac ccgcgacaac ctgctgatgc ggatgaagga cgaggactgg
     2041 caggccatcc tcgacaccaa cctcaccagc gtctaccgca cgtccaaggc ggtcatgcgc
     2101 ggcatgatga aggcgcgcaa gggccgcatc atcaacatcg cctcggtgat cggcgtcacc
     2161 ggcaatgcgg ggcaggccaa ctacgccgcc gccaaggccg g
//
