LOCUS       k141_374               10897 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  k141_374 flag=1 multi=125.0000 len=34781.
ACCESSION   k141_374
VERSION     k141_374
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2022-10-05 22:35:42
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 5828
            Orig. end    :: 16725
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10897
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10828:11725](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5897)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10897
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10897
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     PFAM_domain     377..601
                     /aSDomain="DUF2789"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10982.10"
                     /description="Protein of unknown function (DUF2789)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg101_7_0001"
                     /evalue="1.50E-31"
                     /label="ctg101_7"
                     /locus_tag="ctg101_7"
                     /protein_end="75"
                     /protein_start="0"
                     /score="108.5"
                     /tool="antismash"
                     /translation="MESTVHPFSDLFAQLGLPDDNTSIQQFIAAHSPLPNDMRLEEAPF
                     WSPAQAQLLREERLDDADWAMVVDRLNVAL"
     CDS             377..622
                     /locus_tag="ctg101_7"
                     /transl_table=11
                     /translation="MESTVHPFSDLFAQLGLPDDNTSIQQFIAAHSPLPNDMRLEEAPF
                     WSPAQAQLLREERLDDADWAMVVDRLNVALHASPNP"
     CDS             717..1205
                     /locus_tag="ctg101_8"
                     /transl_table=11
                     /translation="MGIHAEKRGGDDVVGQRLAMRAPENPYQPPSAVIEAGSPRPAQPV
                     GRRPYSLWVVLACYVIYNLLEAVSWLAVLPRDDDLTGVVGSAFYSLGIAICLWRGVNWV
                     RWWVVLTTLLTLLLLMFMVTRGIADNNRVVVIACLLRITVAFLLFLPSVRRWFVPRGA"
     CDS             complement(1230..1442)
                     /locus_tag="ctg101_9"
                     /transl_table=11
                     /translation="MAVCVWPPMPARGERCREWITGVKDGRVYFPWRVLYSTRSRRGQS
                     ASVRRSASIYICGSRLTRTLAGRAQ"
     CDS             complement(1485..1721)
                     /locus_tag="ctg101_10"
                     /transl_table=11
                     /translation="MSVKTITEDGRQLTVQTLQKVDPLGVTYWQGRAMFRIADGRARAD
                     VVTRTRYATRESAENAAIALARANGWVDDATST"
     CDS             1903..2292
                     /locus_tag="ctg101_11"
                     /transl_table=11
                     /translation="MRLFLIAAAALSLSMPLQATSLDGAWVVDLSTQPDTPYTQPMRLT
                     LNADGTVTGSFYNSVIEAGRWKESRGRLCASFRTTDGVGPYHTAVCLTGDTASGQTWAE
                     HRDFLFNWNATRAPVASEPGSTPGR"
     CDS             complement(2341..3003)
                     /locus_tag="ctg101_12"
                     /transl_table=11
                     /translation="MTDTRRLIDQLAARAEPVRPLSSPLRRTAVWVALATLLIAMIASV
                     YGLRTGLRADLAQAPLMLEWIASVLTGLLAAYAVFQISVPGRSPHWMWLPLPALLLWLA
                     GLGWGCLRDYVRMGADAFLMEAVSSECAVAITMTSVPLGLLMLVMVRHAGVVRPAPTAM
                     LVALSAAALSAAGVSLYHGGETALMVLLWHLGAVVVLSLLCLLFGRPLFAWIGYAKR"
     PFAM_domain     complement(2362..2973)
                     /aSDomain="NrsF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06532.13"
                     /description="Negative regulator of sigma F"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg101_12_0002"
                     /evalue="4.20E-34"
                     /label="ctg101_12"
                     /locus_tag="ctg101_12"
                     /protein_end="214"
                     /protein_start="10"
                     /score="118.2"
                     /tool="antismash"
                     /translation="LAARAEPVRPLSSPLRRTAVWVALATLLIAMIASVYGLRTGLRAD
                     LAQAPLMLEWIASVLTGLLAAYAVFQISVPGRSPHWMWLPLPALLLWLAGLGWGCLRDY
                     VRMGADAFLMEAVSSECAVAITMTSVPLGLLMLVMVRHAGVVRPAPTAMLVALSAAALS
                     AAGVSLYHGGETALMVLLWHLGAVVVLSLLCLLFGRPLFAW"
     CDS             complement(2996..3652)
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 117;
                     E-value: 1.2e-35)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg101_13"
                     /transl_table=11
                     /translation="MATLLAFPSPVVVEPQRTDAMPADALQTPAGDDDAWSAWMGRAQG
                     GDNAAYHALLNAIAPYLRAIARRYLGNREDAEDAVQDILIIVHGVRHTYEPGRPFKPWL
                     ATIATRRCIDVLRRRARRVEHEVLAEEPFDRIDEDSPGPEDALARGQAAQHVRRAVADL
                     TPRQQQAIELVHLKDLSLNEASSESRQSVSALKVACHRALKSLRHALGKEDVPHD"
     aSDomain        complement(3023..3505)
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg101_13_0001"
                     /evalue="6.40E-26"
                     /identifier="TIGR02937"
                     /label="ctg101_13"
                     /locus_tag="ctg101_13"
                     /protein_end="210"
                     /protein_start="49"
                     /score="88.9"
                     /tool="antismash"
                     /translation="AYHALLNAIAPYLRAIARRYLGNREDAEDAVQDILIIVHGVRHTY
                     EPGRPFKPWLATIATRRCIDVLRRRARRVEHEVLAEEPFDRIDEDSPGPEDALARGQAA
                     QHVRRAVADLTPRQQQAIELVHLKDLSLNEASSESRQSVSALKVACHRALKSLRHAL"
     PFAM_domain     complement(3035..3187)
                     /aSDomain="Sigma70_r4_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08281.14"
                     /db_xref="GO:0003677"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006352"
                     /db_xref="GO:0006355"
                     /db_xref="GO:0016987"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg101_13_0004"
                     /evalue="1.00E-06"
                     /gene_ontologies="GO:0003677: DNA binding"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006352: DNA-templated transcription,
                     initiation"
                     /gene_ontologies="GO:0006355: regulation of transcription,
                     DNA-templated"
                     /gene_ontologies="GO:0016987: sigma factor activity"
                     /label="ctg101_13"
                     /locus_tag="ctg101_13"
                     /protein_end="206"
                     /protein_start="155"
                     /score="28.4"
                     /tool="antismash"
                     /translation="VRRAVADLTPRQQQAIELVHLKDLSLNEASSESRQSVSALKVACH
                     RALKSL"
     PFAM_domain     complement(3287..3490)
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04542.16"
                     /db_xref="GO:0003700"
                     /db_xref="GO:0006352"
                     /db_xref="GO:0006355"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg101_13_0003"
                     /evalue="5.70E-17"
                     /gene_ontologies="GO:0003700: DNA-binding transcription
                     factor activity"
                     /gene_ontologies="GO:0006352: DNA-templated transcription,
                     initiation"
                     /gene_ontologies="GO:0006355: regulation of transcription,
                     DNA-templated"
                     /label="ctg101_13"
                     /locus_tag="ctg101_13"
                     /protein_end="122"
                     /protein_start="54"
                     /score="61.4"
                     /tool="antismash"
                     /translation="LNAIAPYLRAIARRYLGNREDAEDAVQDILIIVHGVRHTYEPGRP
                     FKPWLATIATRRCIDVLRRRARR"
     CDS             complement(3681..4214)
                     /locus_tag="ctg101_14"
                     /transl_table=11
                     /translation="VSTLDTSPMTAQPRRGAGQRLADALAHVARIPHSLIALLARVSVA
                     VTFWLSGQTKIEGLVLDPLGGTVQLGWPRLSENAIELFRSEYALPLLPPELATYLAAVA
                     EHVFPLLLVIGLASRLSALALLAMTLVIQVFVYPAAFATHGLWAVSLLYVMARGPGVLS
                     LDALIARRYGVSAR"
     PFAM_domain     complement(3804..4106)
                     /aSDomain="DoxX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07681.14"
                     /description="DoxX"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg101_14_0005"
                     /evalue="2.60E-20"
                     /label="ctg101_14"
                     /locus_tag="ctg101_14"
                     /protein_end="137"
                     /protein_start="36"
                     /score="72.9"
                     /tool="antismash"
                     /translation="ALLARVSVAVTFWLSGQTKIEGLVLDPLGGTVQLGWPRLSENAIE
                     LFRSEYALPLLPPELATYLAAVAEHVFPLLLVIGLASRLSALALLAMTLVIQVFVY"
     CDS             complement(4216..5004)
                     /locus_tag="ctg101_15"
                     /transl_table=11
                     /translation="MSAAATLHGAFATALRHAETALPASVAGERAARRLAIHRNTFVVS
                     LVDALAASFPVTQALVGETFFRAMACERVLADPPRSPVLTDYASDFPDFIAGFAPAAAV
                     AGLADVARIEALRIRAYHAADAVPLPDAAYHALLQAPTRLPGTRVVLHPACAWFRASHA
                     ALTVWQAHQGLSDPADARLDGIDTTVPDDVLVARPRLDVRVTALPIGALAWLEALAAGR
                     TLGDAFALAHASSPHTDDGALFALLLAHGLAIAFDLPPES"
     PFAM_domain     complement(4720..4980)
                     /aSDomain="DUF2063"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09836.11"
                     /description="Putative DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg101_15_0006"
                     /evalue="1.60E-21"
                     /label="ctg101_15"
                     /locus_tag="ctg101_15"
                     /protein_end="95"
                     /protein_start="8"
                     /score="76.4"
                     /tool="antismash"
                     /translation="GAFATALRHAETALPASVAGERAARRLAIHRNTFVVSLVDALAAS
                     FPVTQALVGETFFRAMACERVLADPPRSPVLTDYASDFPDFI"
     CDS             complement(5001..5897)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg101_16"
                     /sec_met_domain="DUF692 (E-value: 3.1e-91, bitscore: 296.4,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTRATLPRGTDCLPVDAGLPAQAGIGFKPAHFDGLIADPQPPGFI
                     EVHAENYLGAGGPPHAQLSALCERLPLSVHGVGLSLGGEAPLDTVHLARVQALLARYRP
                     AVFSEHLAWSTHDGRFFNDLLPLRYDAACLARVCRHIEQVQEQLGLQLLLENPSTYFPI
                     AGSTYSEPELLAAIVQRTGCALLLDVNNVHVSCHNQGHDPLAYLAALPLHAVCEIHLAG
                     HARDVDAAGETVLIDDHGAPVDDTVWALYRHVLDRTGPLPTLIEWDTHVPDYATLRAQA
                     RQAQAWLDDAATRRAAA"
     PFAM_domain     complement(5037..5831)
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg101_16_0007"
                     /evalue="2.90E-98"
                     /label="ctg101_16"
                     /locus_tag="ctg101_16"
                     /protein_end="287"
                     /protein_start="22"
                     /score="328.4"
                     /tool="antismash"
                     /translation="AGIGFKPAHFDGLIADPQPPGFIEVHAENYLGAGGPPHAQLSALC
                     ERLPLSVHGVGLSLGGEAPLDTVHLARVQALLARYRPAVFSEHLAWSTHDGRFFNDLLP
                     LRYDAACLARVCRHIEQVQEQLGLQLLLENPSTYFPIAGSTYSEPELLAAIVQRTGCAL
                     LLDVNNVHVSCHNQGHDPLAYLAALPLHAVCEIHLAGHARDVDAAGETVLIDDHGAPVD
                     DTVWALYRHVLDRTGPLPTLIEWDTHVPDYATLRAQARQAQAW"
     CDS             complement(5920..6240)
                     /locus_tag="ctg101_17"
                     /transl_table=11
                     /translation="MSSPFTTAVPAFALAAALGSALAMGATPASAADKAAKERCYGVAM
                     AGKNDCAAGPGTTCAGTSKTDYQANAWKYVPAGTCTKMASKTSPTGFGQLAAFTPKPAK
                     AG"
     PFAM_domain     complement(5986..6132)
                     /aSDomain="DUF2282"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10048.11"
                     /description="Predicted integral membrane protein
                     (DUF2282)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg101_17_0008"
                     /evalue="3.10E-26"
                     /label="ctg101_17"
                     /locus_tag="ctg101_17"
                     /protein_end="85"
                     /protein_start="36"
                     /score="91.3"
                     /tool="antismash"
                     /translation="KERCYGVAMAGKNDCAAGPGTTCAGTSKTDYQANAWKYVPAGTCT
                     KMAS"
     CDS             complement(6358..9216)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg101_18"
                     /sec_met_domain="Pkinase (E-value: 4.3e-35, bitscore:
                     112.4, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSASAARALALFDDYITLTPARRAAALATLAQDDPAAHQLLARLL
                     ASDQALDAGHQSDLLDELPGTLSDLQTASEPGEDARLQQRLGAWRIERLISEGGMGSVY
                     EAQRADGQYQQRVALKCIRRELSSPALIDGFLREREALAALDHPGIATLIDGGVDGDGH
                     PWFAMRYVQGDHIEDWCDARGADLRRRVALLVQACDALAYAHDHGVLHQDIKPSNLMVS
                     DDGQVQLLDFGLTASLAAPGSLPRLAASFGYTAPEAMAGAPPRVTGDVWSMGRLMHVLL
                     AGVLPRSPSVLASVGGQDAAAEPMSALAALQPVGTATARACRTPAVLARQLSGDLDAIV
                     QRATAPSPAARYASITALRADLQAWLELRPVQARDGGMAYRLGRAIARHRTVAAVSAGC
                     ALLLVAGAGVAVWHSLRLAHEAAESQALSQVFEQTVGTATLSGLGATPMSSQQLLADAE
                     RRMRALDLQDHPNVQARGLAMLARNYMAIGDYGRATALAREAGTLQRDDPTRNAATLAA
                     LLNLQGKPAEAGRVAQQALAVADKDTAVAVTLQLLTEQARSQWHRVQHADAYRTLRQAL
                     ALAERTGDTTAQAELRTLRGEWALRQVRFADADADLHAAIRLSGDGAPLVAQAARLLSA
                     HTLMAQGRMEEGQAATRQVLAEYRRLLGDQHPLVGRSWRLLAHGDCVLGRFAPCLAAVE
                     RAEAIVRRDFGEQHPEYADVLRVRALASMFDPASTVDGTALLRRADAILRTAYPPDHTD
                     VLRVESMLARRLLTLPAPTPAARRQQLEDVIGRLDATLAQSRRSGLPVPASHRITLVEA
                     LRERDRPGDLAQARRLLEENRILLRAYTPDFGWRLLNEQLDASLALRDGDLDHADARLS
                     DLLATLPTPPATAAQHRMRGQALVMRAHLALRRGDRVKARAWLDQALAHTQATAGAAHA
                     DTAAMRATLATFERSGRIALPE"
     PFAM_domain     complement(8353..8946)
                     /aSDomain="Pkinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00069.27"
                     /db_xref="GO:0004672"
                     /db_xref="GO:0005524"
                     /db_xref="GO:0006468"
                     /description="Protein kinase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg101_18_0009"
                     /evalue="1.50E-32"
                     /gene_ontologies="GO:0004672: protein kinase activity"
                     /gene_ontologies="GO:0005524: ATP binding"
                     /gene_ontologies="GO:0006468: protein phosphorylation"
                     /label="ctg101_18"
                     /locus_tag="ctg101_18"
                     /protein_end="288"
                     /protein_start="90"
                     /score="113.1"
                     /tool="antismash"
                     /translation="IERLISEGGMGSVYEAQRADGQYQQRVALKCIRRELSSPALIDGF
                     LREREALAALDHPGIATLIDGGVDGDGHPWFAMRYVQGDHIEDWCDARGADLRRRVALL
                     VQACDALAYAHDHGVLHQDIKPSNLMVSDDGQVQLLDFGLTASLAAPGSLPRLAASFGY
                     TAPEAMAGAPPRVTGDVWSMGRLMHVLLAGVLPRS"
     CDS             9544..10263
                     /locus_tag="ctg101_19"
                     /transl_table=11
                     /translation="MLAQAQAADAWTFRLTPYVWGSSTEGSFAHARLPVTVYTSKSFRD
                     SLEELDAGAMGAFEARRGRHGLLLDGQFAKLSTTVQVPVAGAALPVRLKTRTTSGLLAW
                     RYGLVERDATHLDLIAGVRVWSARVRLAYAVPVPTPPPVPQQYSGEQSHRWVDAQVGVK
                     GRHGFGNGVFVGGWVLAGTGESDLSTDLMLLAGYDINERFAVIAGYRRLSTDFETGGGF
                     RFDTTMQGPGLGLEYRF"
ORIGIN
        1 ctcgctttgc tgctggccta catggcctgc atcgtcctct cgcgcagcat cgcctgcccg
       61 cgctgccgga gcgcggtcgg cggctatacc agttggctca acctgcgccc gaatgcagtt
      121 gcccggcgca tcaacttctg cgcgcactgc ggggtggatt tcgacgcgcc tgtcgcgcgc
      181 gcctgatcag catgccgcac gctgatccgc gctctgtcgg ctgcgtagcc cggtccgcgc
      241 agcgaacccg ggatggcttg ccacggaagc cgtccgagtc cgcgggtgcg gccgttggcc
      301 gtacccgggc tacgtgtcag tcactcgctt cacgcatacc cggataggct ggaaccctct
      361 cccacgaggc accgccatgg aatccaccgt ccaccccttc tccgacctgt tcgcccagct
      421 cggcctgccc gacgacaaca ccagcatcca gcagttcatc gccgcccatt ccccgctgcc
      481 caacgacatg cggctggagg aagccccgtt ctggtcgccc gcgcaggcgc agttgctgcg
      541 cgaagagcgg ctggacgatg ccgactgggc gatggtggtg gatcgtttga acgtggcgct
      601 gcacgccagc ccgaacccct agggcgggct caagcccgcc atcgcggacg atcaaatgca
      661 acacggtggc ctagcgccca ccttgcgtct cagtcgcgcg tggcatagtt cggcgcatgg
      721 gaatacatgc cgaaaaacgc ggtggcgatg atgtcgtagg acaacgtctc gccatgcgag
      781 cgcccgagaa tccgtaccag ccgccttctg cggtgatcga agctgggtcc ccgcgtcccg
      841 cacagcccgt tggtcgccgg ccgtattccc tgtgggtggt gctcgcgtgc tacgtaatct
      901 acaacctgct tgaagcagtc tcgtggctgg cggtcctgcc gcgggacgac gacctcaccg
      961 gcgtggtggg gagtgccttc tattcgcttg gcatcgcaat ctgcctgtgg cggggcgtga
     1021 actgggtgcg atggtgggtc gtgctcacca cgctgctgac tctgctcttg ttgatgttca
     1081 tggtcacgcg cggcatcgca gacaacaacc gcgttgtggt gatcgcgtgt ctcctgcgca
     1141 tcaccgtagc cttcctgttg ttcctgccgt cagtgcgccg atggttcgta cctcgcggcg
     1201 cctgagtccg tagggcgagc tcaagcccgt cattgcgcgc gccctgctag cgtccgcgtg
     1261 agcctgctgc cgcaaatgta aatggacgcg gacctccgca ccgacgcaga ctgcccgcgt
     1321 cgggagcgtg tggaatacaa caccctccac gggaaataca cacgaccgtc cttgactccg
     1381 gtgatccact cccgacacct ctcgccgcgc gccggcatcg gcggccagac gcagaccgcc
     1441 atcttcattc cgatgcgatc acgcgcggtg ggccaaggcc caccctacgt ggaggtggcg
     1501 tcgtccaccc agccgttcgc gcgggccagg gcgatggcgg cgttctcggc ggattcgcgc
     1561 gtggcgtagc gcgtgcgcgt gaccacgtcg gcgcgggcgc ggccatcggc gatgcggaac
     1621 atggcgcggc cctgccagta ggtgacgccg agcggatcga ctttctgcag cgtctgcacg
     1681 gtcagctggc ggccgtcttc ggtgatcgtc ttgacgctca tgccacgacc ttacctccaa
     1741 acgcgggcag ttgtcgccac ggccgcggga ggcgcgcgac ggcggccgca tcgggggagg
     1801 gaaggcacat gcccccgcag gcacaccgtc gtcgtggtcg cgcatccgtt ctacctgcgt
     1861 gacgcgtagc gctggagcct cccgccgaaa aacggaatcc cgatgcgcct gtttctgatc
     1921 gccgccgccg cgctgtcctt gtccatgccc ctgcaggcca cgtcgctgga cggggcctgg
     1981 gtggtggacc tgtccaccca gccggacacg ccctatacgc agcccatgcg actcacgctc
     2041 aacgccgacg gcacggtgac gggcagcttc tacaacagcg tcatcgaggc cggccggtgg
     2101 aaggaaagcc gcggccgcct gtgcgccagt ttccgcacta ccgatggcgt ggggccgtac
     2161 cacaccgcgg tctgcctgac cggcgacacc gccagtggac agacctgggc cgagcaccgc
     2221 gacttcctgt tcaactggaa cgccacgcgt gcgccggtcg ccagcgagcc tggatccacg
     2281 cccgggcgtt gaccgcgccg cacgttgtcg acaggcggcg catcgtccgt gcgtgacgta
     2341 tcagcgcttg gcgtagccga tccacgcgaa cagcgggcgg ccgaacagca ggcacagcag
     2401 cgacagcacg accaccgcgc ccaggtgcca cagcagcacc atcagcgcgg tctcgccgcc
     2461 gtggtacagg ctgacgccgg cggcggacag cgcggccgcg ctcagcgcca ccagcatcgc
     2521 cgtcggcgcg ggccgcacca cgccggcgtg gcgcaccatc accagcatca gcaggcccag
     2581 cggcacgctg gtcatggtga tggccacggc gcattccgaa ctgaccgctt ccatcaggaa
     2641 ggcatccgcg cccatgcgca cgtagtcgcg caggcagccc cagcccagcc cggccagcca
     2701 cagcagcagc gccggcagcg gcagccacat ccagtgcggt gagcgccccg gtacgctgat
     2761 ctggaacacc gcgtacgccg ccagcagccc ggtcagcaca ctggcgatcc attccagcat
     2821 cagcggcgcc tgcgccaggt ccgccctcag gccggtgcgc aggccgtaga ccgaggcgat
     2881 catcgcgatc agtagcgtgg ccagcgccac ccacaccgcg gtgcggcgca gcggcgagga
     2941 cagcgggcgc accggttcgg cacgcgcggc caactggtcg atcaggcggc gggtatcagt
     3001 catgggggac gtcctctttg cccagggcgt gccggagcga tttcagcgcg cggtggcagg
     3061 ccaccttcag cgcgctgacg ctctgtcggc tttccgacga ggcttcattc aacgacaggt
     3121 ctttcaggtg caccagttcg atggcctgct gctggcgcgg cgtcaggtcc gccactgcgc
     3181 ggcgcacgtg ctgcgcggcc tggccgcggg cgagggcgtc ctcgggcccg gggctgtcct
     3241 cgtcgatgcg gtcgaacggt tcctcggcca gcacttcgtg ctccacgcgc cgcgcgcgcc
     3301 ggcgcagcac gtcgatgcag cggcgcgtgg cgatggtggc cagccagggc ttgaacgggc
     3361 gtccgggttc gtaggtgtgg cgcacgccgt gcacgatgat gaggatgtcc tgcacggcgt
     3421 cttcggcgtc ctcgcggttg cccaggtagc ggcgcgcgat ggcgcgcagg tacggcgcga
     3481 tggcgttgag cagggcgtgg tacgccgcgt tgtcgccgcc ctgcgcgcgc cccatccacg
     3541 cgctccacgc gtcgtcgtcg cccgcaggcg tctgcagggc gtcggcaggc atcgcatcgg
     3601 tgcgctgcgg ctcgaccacg acgggtgacg ggaaagcgag gagggtggcc atcatgcggc
     3661 tcgcgtcggt ggctgccaag tcaacgcgcg gacacgccgt agcggcgtgc gatcagggcg
     3721 tccagcgaca gcacgcccgg tccgcgcgcc atgacgtaca gcagcgacac cgcccacagg
     3781 ccgtgcgtcg cgaacgcggc cggatatacg aagacctgga tcaccagcgt catcgccagc
     3841 agcgccagcg ccgacagccg gctggccagg ccgatcacca gcagcagcgg gaacacatgc
     3901 tcggcgacgg ccgcgagata cgtggccagc tcgggcggca gcagcggcag cgcgtactcg
     3961 ctgcggaaca gttcgatcgc gttctccgat aggcgcggcc atcccagctg caccgtgcca
     4021 ccgagcgggt ccagcaccag cccttcgatc ttggtctgcc ccgacagcca gaacgtcacc
     4081 gccaccgaca cgcgcgccag caatgcgatc aggctgtgcg ggatgcgcgc gacgtgcgcc
     4141 agcgcgtcgg ccaggcgctg cccggcgccg cgacgcggtt gtgcggtcat gggagaggta
     4201 tcgagggtgc tcacatcagg actccggtgg aaggtcgaag gcaatggcca ggccatgcgc
     4261 cagcagcagg gcgaacagcg cgccgtcatc ggtgtgcggc gaggacgcat gcgccagggc
     4321 gaaggcgtcg ccgagcgtgc ggccggcagc gagtgcctcg agccaggcga gggcgccgat
     4381 gggcagtgcg gtcacgcgga cgtccaagcg cgggcgtgcg accaggacgt cgtcgggcac
     4441 ggtggtgtcg atgccatcca gtcgcgcgtc ggccggatcg gacagtccct ggtgcgcctg
     4501 ccatacggtc agcgcggcat gtgacgcgcg gaaccacgcg caagccggat gcagcacgac
     4561 gcgcgtgccg ggcaggcgcg tcggtgcctg cagcagggcg tggtaggcgg cgtcgggcag
     4621 cggcacggca tcggcggcgt ggtaggcgcg gatgcgcagc gcttcgatgc gcgccacgtc
     4681 ggccaggccg gcgaccgcgg cggccggcgc gaagccggcg atgaaatcgg ggaagtccga
     4741 cgcatagtcg gtcagcaccg gtgatcgcgg cggatccgcc agcacacgct cgcacgccat
     4801 cgcgcggaag aacgtctcgc ccaccagcgc ctgcgtcacc ggaaacgagg cagccagcgc
     4861 atcgaccagg ctgacgacga aggtgttgcg atggatcgcc aggcggcgtg cggcgcgctc
     4921 gccggcgacg ctggcaggca aggcggtctc cgcatgccgc agcgcggtcg cgaaggcgcc
     4981 gtgcagggtg gctgcggcgc tcatgccgcg gcgcgccggg tggccgcgtc gtccagccac
     5041 gcctgcgcct gccgcgcctg cgcgcgcagg gtggcgtagt cgggcacgtg cgtgtcccat
     5101 tcgatcagtg tgggcagcgg cccggtgcgg tccaggacgt gccggtacag cgcccagacc
     5161 gtgtcatcga ccggcgcgcc gtggtcgtcg atcagcaccg tctcgccggc ggcatcgaca
     5221 tcgcgcgcat ggccggccag gtggatctcg cacactgcgt gcagcggcag tgcggcgaga
     5281 tacgcgagcg gatcgtggcc ctggttgtgg caggacacgt gcacgttgtt gacgtccagc
     5341 agcagtgcgc agccggtgcg ctgcacgatg gccgccagca gctcgggctc gctgtaggtg
     5401 ctgccggcga tggggaaata ggtgctggga ttttccagca gcagttgcag gcccagctgt
     5461 tcctgcacct gttcgatatg ccggcagacg cgggccaggc aggcggcgtc atagcgcagc
     5521 ggcagaaggt cgttgaagaa gcggccgtcg tgcgtggacc acgccaggtg ttcggagaac
     5581 acggccggcc ggtagcgcgc gagcaatgcc tgcacgcggg caagatggac ggtgtcgagt
     5641 ggcgcttcgc cgcccaggga caggccgacg ccatgcacgg agagcggcag ccgttcgcac
     5701 agcgcggaca gctgcgcatg cggagggcca cccgcaccga gatagttttc cgcatgcact
     5761 tcgatgaagc cgggcggctg cgggtcggcg atcagcccat cgaagtgcgc gggcttgaaa
     5821 ccgatgccgg cctgcgcggg caggccggca tcgaccggga gacagtcggt gccacgggga
     5881 agggtcgcac gggtcaccgt cgcatctcca gcgttgcgat caaccggcct tggcaggctt
     5941 gggcgtgaac gccgctagct ggccgaagcc ggtcggcgag gtcttcgacg ccatcttggt
     6001 gcaggtgccg gccggcacgt acttccacgc gttggcctgg taatcggtct tcgaggtacc
     6061 ggcgcaggtg gtgcccggac cggcggcgca gtcgttcttg ccggccatgg ccacgccgta
     6121 gcagcgttcc ttggcggcct tgtcggcggc ggaggcgggc gtggcgccca tggccagggc
     6181 cgaaccgagg gcggcggcga gggcgaaggc ggggacggcg gtggtgaagg ggctggacat
     6241 cgggaagtct cctgtaggtg gaccggaggg gccggcaccg tgccggatgt ccctctcgca
     6301 ggaagacttc gtaccgggag cggaaaaggt tacgtccgcc gttgcgcgga cacgcgctca
     6361 ctcgggcagg gcgatgcggc cgctgcgctc gaaggtggcc agcgtggcgc gcatcgcggc
     6421 ggtgtcggca tgcgccgcgc cggcggtggc ctgcgtgtgc gccagcgcct ggtccagcca
     6481 ggcgcgtgcc tttacgcggt cgccgcggcg cagggccagg tgggcgcgca tcaccagcgc
     6541 ctgtccgcgc atcctgtgtt gcgccgccgt agccggtggc gtcggcagcg tggcgagcag
     6601 gtcggacagg cgggcgtcgg cgtggtccag gtcgccgtcg cgcagcgcca gcgaggcgtc
     6661 cagttgctcg ttgagcaggc gccagccgaa gtcgggcgtg taggcgcgca gcagtatccg
     6721 gttttcctcc agcaggcgtc gcgcctgggc gaggtcgccg ggacggtcgc gctccctcag
     6781 ggcctcgacc agggtgatgc ggtgcgaggc cggcaccggc agcccactac gccggctctg
     6841 cgccagggtc gcgtcgagcc ggccgatgac gtcttccagt tgctgcctgc gggccgcggg
     6901 ggtcggcgcc gggagggtca gcaggcgccg cgccagcatc gattccaccc gcagcacgtc
     6961 ggtgtggtcc ggtggatagg ccgtgcgcag aatggcatcg gcgcggcgca gcagggcggt
     7021 gccgtcgacc gtgctggccg ggtcgaacat cgacgccagc gcgcgcacgc gcagcacgtc
     7081 ggcgtattcc ggatgctgct cgccgaagtc gcggcggacg atggcctcgg cgcgctccac
     7141 ggcggcgagg cagggagcga agcggcccag cacgcagtcg ccgtgcgcca gcaggcgcca
     7201 gctgcggccc accagcggat gctgatcgcc cagcaggcga cggtactcgg ccagcacctg
     7261 gcgggtggcg gcctggcctt cctccatccg gccctgcgcc atcagcgtgt gggcggacag
     7321 caggcgggcc gcctgcgcca ccagcggcgc gccatcgccg gacaggcgga tggcggcgtg
     7381 caggtcggcg tcggcatcgg cgaagcgcac ctgccgcagc gcccactcgc cgcgtagcgt
     7441 gcgcagttcg gcctgcgcgg tggtgtcgcc ggtgcgctcg gccagcgcca gcgcctgccg
     7501 cagcgtgcgg taggcgtcgg cgtgctgcac gcggtgccac tggctgcgtg cctgttcggt
     7561 cagcagctgc agcgtcacgg cgacggcggt gtccttgtcc gcgacggcca gcgcctgctg
     7621 cgccacgcgg ccggcctcgg ctggcttgcc ctgcaggttg agcagggcgg ccagcgtggc
     7681 ggcgttgcgg gtgggatcgt cgcgctgcag ggtgccggcc tcgcgggcca gggcggtggc
     7741 gcggccgtag tcgccgatgg ccatgtagtt gcgcgccagc atcgccagcc cgcgggcctg
     7801 cacgttggga tggtcctgca ggtcgagcgc gcgcatgcgc cgttcggcgt cggcgagcag
     7861 ctgctgcgag gacatcggcg tggcgcccag ccccgacagc gtagcggtgc cgacggtctg
     7921 ctcgaacacc tgcgacagcg cctgcgattc ggccgcctcg tgcgccagcc gcaggctgtg
     7981 ccagaccgcc acgccggcgc cggcgaccag cagcagcgcg cagccggccg acaccgcggc
     8041 caccgtgcga tggcgggcga tcgcgcggcc caggcgatag gccatgccgc cgtcgcgggc
     8101 ttgcacgggg cgcagctcca gccaggcctg caggtcggcg cgcagcgccg tgatggaggc
     8161 gtagcgcgcg gcgggcgagg gtgccgtggc gcgttgcacg atggcgtcca ggtcgccgga
     8221 caactgccgc gccagtaccg ccggcgtgcg acaggcgcgc gccgtggcgg tgcccacggg
     8281 ttgcagcgcg gccagcgcgg acatcggctc ggcagcggcg tcctggccgc cgacggaggc
     8341 cagcacggac gggctgcgcg gcagcacacc ggccagcagc acatgcatca gccggcccat
     8401 cgaccagaca tcgccggtca cccgcggcgg cgcgccggcc atcgcctccg gcgcggtata
     8461 gccgaacgac gcggcaagcc gcggcaggct gcccggcgcg gcgagcgagg cggtcaggcc
     8521 gaagtcgagc agctgcacct ggccgtcgtc gctgaccatc aggttggacg gcttgatgtc
     8581 ctggtgcagc acgccgtggt cgtgcgcgta cgccagcgcg tcgcaggcct gcaccagcag
     8641 cgccacgcgc cggcgcaggt cggcgccgcg cgcgtcgcac cagtcctcga tgtggtcgcc
     8701 ctgcacgtaa cgcatcgcga accagggatg gccgtcgcca tccacgccgc catcgatcag
     8761 ggtggcgatg ccgggatggt ccagcgcggc cagcgcctcg cgctcgcgca ggaagccgtc
     8821 gatcagtgcg ggcgaggaga gctcgcgacg gatgcacttc agcgccaccc gttgctggta
     8881 ctggccgtcg gcgcgttgcg cctcgtagac gctgcccatg ccgccttcgc tgatcaggcg
     8941 ctcgatccgc cacgctccca gccgctgctg caggcgcgcg tcctcgccgg gttcggatgc
     9001 ggtctgcagg tccgacaggg tgccgggcaa ttcgtccagc aggtcggact ggtggcccgc
     9061 atccagcgcc tggtcggagg ccagcagccg ggccagcagc tggtgcgcgg ccgggtcgtc
     9121 ctgcgccagc gtcgccagcg cggcggcacg ccgcgccggc gtgagcgtga tgtagtcgtc
     9181 gaacagcgcc agtgcgcgcg cggcggaggc actcatgtcc gcgcctgcgt cgcgcgcgga
     9241 cggcgtcggg aacctggcgt gcgccgcagc ggcggacggg aaggggagac ctgcatcgcg
     9301 agtgccctgg gcccggggag tgcgggcggt gtcatgtgag gtgatcgggc cgtcgcggcc
     9361 ggagaggacg cgggaccgat ggcagtcgac tcacattggt gctacacagg cggccgcggg
     9421 gagcgcggca aggcagcggt tccgccgccc gtcgcggggc aggggcgacg gccaccacga
     9481 gggaacggca tggcgatcac atggcgtgtc agggtgttgg cggggctggt gtgcagcgca
     9541 ccgatgctgg cgcaggcaca ggccgcggat gcgtggacgt tccggctgac gccgtatgtc
     9601 tggggctcgt cgaccgaggg ctcgttcgcc cacgcgcggc tgccggtgac ggtatatacc
     9661 tccaagagct tccgcgactc gctggaggaa ctggacgccg gcgcgatggg cgcgttcgag
     9721 gcgcgcaggg gccgccacgg cctgctgctg gacggccagt tcgccaagct ctccaccacc
     9781 gtgcaggtgc cggtcgccgg cgccgcgttg ccggtgcggt tgaagacgcg caccaccagc
     9841 ggtctgctcg cctggcgcta cggcctggtc gaacgcgacg ccacccacct ggacctgata
     9901 gccggcgtgc gcgtgtggtc ggcgcgcgtg cgcctggcgt acgccgtgcc cgtgccgaca
     9961 ccgccgccgg tgccacagca gtattcgggc gagcagtcgc accgctgggt cgatgcgcag
    10021 gtcggcgtga agggacggca cggcttcggc aacggcgtgt tcgtcggcgg ctgggtgctg
    10081 gccggcaccg gcgaatccga cctctccacc gacctgatgc tgctggccgg ctatgacatc
    10141 aacgaacgct tcgcggtgat cgccggctac cggcggttgt cgaccgactt cgagaccggc
    10201 ggcggcttcc gcttcgacac cacgatgcag ggccccggcc tggggctgga ataccggttc
    10261 tgatcgcccc cacgcacagg agtgacgcca tggagatcgc acgtaccgcg ttgcacaccg
    10321 ccgtgttgct gctggccacc gccagtgtcg gcgcgcaggc ttgggccgcg caggccgaca
    10381 cggcgctgcg tgacgccgcc acgcaggcgc agccggcggt gatcgaaacg ctgcgcgaac
    10441 tggtgacgac cgaatccggt tccaccgacc acgaaggcgt cgccacgctg atgacgtacc
    10501 tcggtacgcg gctgcgcgcg ctggatgcga aggtcgaccg catgccctct gcgaccggcg
    10561 gcccggacct ggtgcgcggc gtgttcagtg gcaacggcgc gctgaaggtg atgctgatcg
    10621 cccacgccga caccgtgtac gaccgcggca tcctggcgcg cgagccgtac cagcaaaaag
    10681 gcagcctgct gtacggcccc ggcatcgccg acgacaaggg cggcattgcg gtgatcctgc
    10741 atgccatggc gttgttgaag gcgcgcgcct ggaacgatta cgccacggtc acggtgctgt
    10801 tcaatccgga cgaggaaatc ggctcgcccg gttccggcga gaccatcgcc acgctcgccg
    10861 ccgcgcacga cgtggtgctg tcgttcgagc cctcgcc
//
