LOCUS       k141_497                1705 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  k141_497 flag=1 multi=123.0000 len=1705.
ACCESSION   k141_497
VERSION     k141_497
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2022-10-05 22:35:42
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 1705
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..348
                     /locus_tag="ctg345_1"
                     /transl_table=11
                     /translation="IDAIHRMGVSLSIDDFGTGYSSLSHLHRLPISELKLDMSFVRDLE
                     HSESARALTTSILRIGESLSLKVVAEGVENAAQRAVLASLNCDLLQGYYVSRPLSPHSL
                     ERWVSLQPPAE"
     protocluster    1..1705
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1208:1703](-)"
                     /cutoff="5000"
                     /detection_rule="Trp_halogenase"
                     /neighbourhood="10000"
                     /product="halogenated"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(1209..1703)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="Trp_halogenase"
                     /neighbourhood="10000"
                     /product="halogenated"
                     /protocluster_number="1"
     cand_cluster    1..1705
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="Trp_halogenase"
                     /kind="single"
                     /product="halogenated"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..1705
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="halogenated"
                     /region_number="1"
                     /rules="Trp_halogenase"
                     /tool="antismash"
     PFAM_domain     4..294
                     /aSDomain="EAL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00563.22"
                     /description="EAL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg345_1_0001"
                     /evalue="2.10E-33"
                     /label="ctg345_1"
                     /locus_tag="ctg345_1"
                     /protein_end="98"
                     /protein_start="1"
                     /score="115.8"
                     /tool="antismash"
                     /translation="DAIHRMGVSLSIDDFGTGYSSLSHLHRLPISELKLDMSFVRDLEH
                     SESARALTTSILRIGESLSLKVVAEGVENAAQRAVLASLNCDLLQGYYVSRP"
     CDS             complement(323..1192)
                     /locus_tag="ctg345_2"
                     /transl_table=11
                     /translation="MAYAAGMIDTRLEDFVSAHRRLFVLTGAGCSTASGIPDYRDEQGA
                     WKRTPPVTYQAFVGDRATRQRYWARSLLGWPRVAAARPNAAHVALAALEAKGGCEVLLT
                     QNVDGLHQAAGSVSVIDLHGRLGGVVCLGCAAVSGRAQLQQRLAQANPAWLSLDAGTAP
                     DGDADLEGRDFGTFEVPACEACGGLLKPDVVFFGENVPRLRVETAMTHLGHADAMLVVG
                     SSLMVYSGLRFVHAAVRLGLPVAAVGLGRTRADDLLQFRLAAPCGEALDFLLDDAGSPA
                     LTRPAVAG"
     PFAM_domain     complement(506..1114)
                     /aSDomain="SIR2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02146.19"
                     /db_xref="GO:0070403"
                     /description="Sir2 family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg345_2_0002"
                     /evalue="2.20E-43"
                     /gene_ontologies="GO:0070403: NAD+ binding"
                     /label="ctg345_2"
                     /locus_tag="ctg345_2"
                     /protein_end="229"
                     /protein_start="26"
                     /score="148.4"
                     /tool="antismash"
                     /translation="GAGCSTASGIPDYRDEQGAWKRTPPVTYQAFVGDRATRQRYWARS
                     LLGWPRVAAARPNAAHVALAALEAKGGCEVLLTQNVDGLHQAAGSVSVIDLHGRLGGVV
                     CLGCAAVSGRAQLQQRLAQANPAWLSLDAGTAPDGDADLEGRDFGTFEVPACEACGGLL
                     KPDVVFFGENVPRLRVETAMTHLGHADAMLVVGSSLMVYS"
     CDS             complement(1209..1703)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     halogenated: Trp_halogenase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg345_3"
                     /sec_met_domain="Trp_halogenase (E-value: 9.4e-47,
                     bitscore: 147.4, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="FIEPLESTTIHLIQRGIVRLLQTFPHTITQPAIDEYNARLDEELQ
                     HVRDFVIMHYKVSDRRDSPYWREIAEMEIPSTLRHRIDLFRETGTVFHVPGELFGENSW
                     IQVMMGQGIVPKRYHPTADVMSPADLQRFLDDIRRNVLDTARQMPAHMDYLRSYCPAPK
                     P"
     PFAM_domain     complement(1326..1703)
                     /aSDomain="Trp_halogenase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04820.16"
                     /description="Tryptophan halogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg345_3_0003"
                     /evalue="6.00E-43"
                     /label="ctg345_3"
                     /locus_tag="ctg345_3"
                     /protein_end="126"
                     /protein_start="0"
                     /score="147.4"
                     /tool="antismash"
                     /translation="FIEPLESTTIHLIQRGIVRLLQTFPHTITQPAIDEYNARLDEELQ
                     HVRDFVIMHYKVSDRRDSPYWREIAEMEIPSTLRHRIDLFRETGTVFHVPGELFGENSW
                     IQVMMGQGIVPKRYHPTADVMS"
ORIGIN
        1 atcgatgcga tccaccggat gggcgtcagc ctgtcgatcg acgatttcgg caccggctac
       61 tccagcctga gccatctgca ccgcctgccg atcagcgaac tgaagctgga catgagcttc
      121 gtccgcgacc tggagcacag cgagtccgcg cgcgcactga ccacctcgat cctgcgcatc
      181 ggcgagagcc tgtccctgaa agtggtggcg gagggcgtgg agaacgccgc ccagcgcgcc
      241 gtgctggctt cgctcaactg cgacctgctg cagggctact acgtctcccg tccgctctcg
      301 ccgcactcgc tggagcgctg ggtcagcctg caaccgccgg ccgagtgagg gccgggcttc
      361 ctgcatcgtc cagcaggaag tcgagcgctt cgccgcacgg ggccgccagc cggaactgca
      421 gcagatcatc ggcgcgcgtg cgacccaggc ctaccgccgc caccggcagc cccaggcgga
      481 cagccgcgtg cacaaagcgc agccccgaat agaccatcag cgacgaaccg acgaccagca
      541 tggcgtcggc gtgcccgagg tgcgtcatcg cggtctcgac acgcagccgc ggcacgttct
      601 cgccgaagaa caccacgtcc ggcttgagca gtccgccgca ggcctcgcag gcgggcacct
      661 cgaacgtgcc gaagtcccgg ccctccagat cggcgtcgcc gtccggcgcc gtacccgcgt
      721 ccagcgacag ccacgccgga ttggcctgcg ccagccgctg ttgcagctgc gcacggcctg
      781 ataccgcagc gcagcccagg cagacgaccc cgccgagccg cccgtgcagg tcgatcaccg
      841 acacgctgcc ggcggcctgg tgcaggccgt ccacgttctg ggtcagcagc acttcgcaac
      901 cgcccttggc ttccagcgcc gccagggcga catgcgccgc attcggccgc gccgcggcga
      961 cgcgcggcca tccgagcagg ctgcgcgccc agtagcgctg gcgtgtggcg cgatcgccga
     1021 cgaaggcctg gtaggtcacc ggcggcgtgc gcttccaggc gccctgctcg tcccggtagt
     1081 cggggatgcc ggacgcggta ctgcagccgg cgccggtcag cacgaacagg cgccggtgcg
     1141 ccgaaacgaa gtcttccagt cgcgtgtcga tcatgccggc agcataggcc atgccgcgcc
     1201 ggcgtggctc agggcttcgg cgcgggacag tagctgcgca ggtagtccat gtgggccggc
     1261 atctgcctgg ccgtgtccag gacattgcgg cggatgtcgt cgaggaaacg ttgcaggtcc
     1321 gccggcgaca tcacgtccgc agtcgggtgg tagcgcttcg gcacgatgcc ctggcccatc
     1381 atcacctgga tccaggaatt ctcgccgaac agttcgccgg gaacatggaa cacggtgccg
     1441 gtctcgcgga acaggtcgat gcgatgccgc agcgtggacg ggatttccat ctcggcgatc
     1501 tcgcgccagt acggcgagtc gcgccggtcg ctgaccttgt agtgcatgat cacgaagtcg
     1561 cggacatgct gcagctcttc gtccagacgc gcgttgtact cgtcgatcgc cggctgggtg
     1621 atggtgtgcg gaaacgtctg cagcaggcgc acgatgccgc gctggatcag gtggatggtg
     1681 gtcgattcca gcggctcgat gaaac
//
